• geographic ulcer
  • Application of steroids to a dendritic ulcer caused by HSV will result in rapid and significant worsening of the ulcer to form an 'amoeboid' or 'geographic' ulcer, so named because of the ulcer's map like shape. (wikipedia.org)
  • antiviral
  • Infectious keratitis can progress rapidly, and generally requires urgent antibacterial, antifungal, or antiviral therapy to eliminate the pathogen. (wikipedia.org)
  • clinical
  • A specific clinical diagnosis of HSV as the cause of dendritic keratitis can usually be made by ophthalmologists and optometrists based on the presence of characteristic clinical features. (wikipedia.org)
  • Diagnostic testing is seldom needed because of its classic clinical features and is not useful in stromal keratitis as there is usually no live virus. (wikipedia.org)
  • Laboratory tests are indicated in complicated cases when the clinical diagnosis is uncertain and in all cases of suspected neonatal herpes infection: Corneal smears or impression cytology specimens can be analyzed by culture, antigen detection, or fluorescent antibody testing. (wikipedia.org)
  • viruses
  • Ganciclovir is phosphorylated to a substrate, which competitively inhibits the binding of deoxyguanosine triphosphate to DNA polymerase resulting in inhibition of DNA replication by herpes simplex viruses. (drugs.com)
  • He has authored over 100 published papers and several book chapters on herpes viruses. (wikipedia.org)
  • feline
  • However, many healthy cats are subclinical carriers of feline herpes virus, so a positive test for FHV-1 does not necessarily indicate that signs of an upper respiratory tract infection are due to FVR. (wikipedia.org)
  • severe
  • The global incidence (rate of new disease) of herpes keratitis is roughly 1.5 million, including 40,000 new cases of severe monocular visual impairment or blindness each year. (wikipedia.org)
  • immune
  • Plasmacytoid dendritic cells (pDCs) represent a highly functional subset of bone marrow (BM)-derived cells and play a key role in linking the innate and adaptive immune responses. (arvojournals.org)