• The only curative treatment for acute liver failure is liver transplantation, but there are many restrictions on the application of liver transplantation. (springer.com)
  • The aims of this article are to review the current knowledge regarding therapeutic mechanisms of mesenchymal stem cells in acute liver failure, to discuss recent advancements in preclinical and clinical studies in the treatment of mesenchymal stem cells, and to summarize the methodological improvement of mesenchymal stem cell transplantation in treating liver failure. (springer.com)
  • The only curative treatment for ALF is liver transplantation, but there are many restrictions on the application of liver transplantation because of financial considerations, a shortage of donor livers, and immunosuppression-related complications [ 3 ]. (springer.com)
  • Although liver failure can be treated via hepatocyte transplantation, it also faces multiple problems comprising the shortage of high-quality hepatocytes sources, rejection of allogeneic transplants, difficulty to expand, and losing hepatic characteristics in vitro [ 7 , 8 ]. (springer.com)
  • Acetaminophen (APAP) poisoning is one of the leading causes of acute hepatic failure and liver transplantation is often the only lifesaving alternative. (mdpi.com)
  • 1 Surgical Research Laboratory and Section of Hepatobiliary Surgery and Liver Transplantation, Department of Surgery, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands. (nih.gov)
  • Wilson's disease in children: 37-year experience and revised King's score for liver transplantation. (thieme-connect.de)
  • 10. Mochida S, Nakayama N, Matsui A, Nagoshi S, Fujiwara K. Re-evaluation of the Guideline published by the Acute Liver Failure Study Group of Japan in 1996 to determine the indications of liver transplantation in patients with fulminant hepatitis. (intramed.net)
  • The faculty have a variety of clinical protocols dealing with diabetic nephropathy, bone disease, progression of kidney disease, kidney transplantation, vitamin deficiency in chronic kidney disease, end-stage renal disease, transplantation and nutrition in patients with acute kidney injury. (usc.edu)
  • Prof. Sundaram was one of the leading researchers in the field of acute-on-chronic liver failure and was actively involved in studies aiming at improving the outcomes of patients after liver transplantation. (easl.eu)
  • Dr. Maley serves as the director of the Jefferson Transplant Institute, Division of Transplantation and Live Donor Liver Transplant Program at Thomas Jefferson University Hospital. (donors1.org)
  • He is also the Nicoletti Family Professor of Transplantation Surgery at Jefferson Medical College and surgical director of the Liver Transplant Program. (donors1.org)
  • Dr. Maley has performed extensive research in the fields of liver transplantation and surgical therapy to improve patient safety and care. (donors1.org)
  • He is a member of the Alpha Omega Alpha Medical Honor Society, the American Association for the Study of Liver Diseases, the American Society of Transplantation and the American Society of Transplant Surgery. (donors1.org)
  • He has published research studies in such leading journals as Transplant Proceedings, Transplantation, Liver Transplantation and Annals of Surgery, and he has authored or co-authored eight book chapters. (donors1.org)
  • Liver Transplantation. (mssm.edu)
  • My primary research interest is in health outcomes following pediatric liver transplantation and acute liver failure. (northwestern.edu)
  • Treatment is mainly supportive, sometimes with liver transplantation and/or specific therapies (eg, N - acetylcysteine for acetaminophen toxicity). (msdmanuals.com)
  • A Swedish boy who had experienced severe ALAD deficiency porphyria (ADP) attacks refractory to treatment since birth underwent liver transplantation at age 6. (medscape.com)
  • Potentially curative treatments, such as liver transplantation, hepatic resection, or local ablative therapies, having a 5-year survival of 40-70%, can only be offered to patients with early stage HCC. (medscape.com)
  • Acute hepatitis E virus infection during pregnancy has a high fatality rate in developing countries. (cdc.gov)
  • As part of a series of studies to evaluate the therapeutic efficacy of ammonia-lowering agents, groups of rats with ALF caused by hepatic devascularization were treated with L-ornithine-L-aspartate (OA), an agent shown previously to be effective in reducing blood ammonia concentrations in both experimental and human chronic liver failure. (nih.gov)
  • ACG Offers Guidelines for Acute-on-Chronic Liver Failure A conversation with the lead author behind the recently published recommendations on how to manage this major cause of mortality in patients with chronic liver disease. (medscape.com)
  • Acquired dysfunctional immunity in cirrhosis predisposes patients to frequent bacterial infections contributing to disease progression and may lead to the development of acute-on-chronic liver failure (ACLF) ( 1 ). (frontiersin.org)
  • Hemostatic changes in acute-on-chronic liver failure (ACLF) may in part reflect critical illness. (nih.gov)
  • ABSTRACT: Background Even the sickest patients with chronic liver disease (CLD), such as those with acute-on-chronic liver failure (ACLF) remain in hemostatic balance due to a concomitant decline in pro- and antihemostatic factors. (nih.gov)
  • The common end stage of liver disease is decompensated cirrhosis and the further development towards acute-on-chronic liver failure (ACLF). (ku.dk)
  • In this Review, the authors discuss the possible pathogenic, diagnostic and therapeutic role of the gut microbiota in decompensation of cirrhosis and progression to acute-on-chronic liver failure. (ku.dk)
  • Acute on Chronic Liver Failure: A New Disease Entity? (ucsd.tv)
  • WASHINGTON - Treatment with carvedilol reduced the incidence of sepsis and acute kidney injury and improved survival at 28 days but did not significantly reduce the progression of esophageal varices in patients with acute-on-chronic liver failure. (the-hospitalist.org)
  • A total of 136 patients with acute-on-chronic liver failure with small or no esophageal varices and a hepatic venous pressure gradient (HVPG) of 12 mm Hg or greater were enrolled in a single center, prospective, open-label , randomized controlled trial: 66 were randomized to carvedilol and 70 to placebo, according to Sumeet Kainth , MD, of the Institute of Liver and Biliary Sciences in New Delhi. (the-hospitalist.org)
  • Morbidity and mortality were high, as is expected with acute-on-chronic liver failure, he noted. (the-hospitalist.org)
  • Acute liver failure is the most severe type, developing over days, unlike chronic liver failure that can simmer for years because of alcohol abuse or viral hepatitis. (natap.org)
  • These nononcotic properties explain why long-term albumin administration in patients with decompensated cirrhosis may be useful in the prevention of associated complications (acute-on-chronic liver failure, infections). (ibecbarcelona.eu)
  • Acute-on-chronic liver failure is a distinct syndrome that develops in patients with acute decompensation of cirrhosis. (jptcp.com)
  • Infection and sepsis are a main cause of acute-on-chronic liver failure (ACLF). (springeropen.com)
  • Acute on chronic liver failure: prognostic models and artificial intelligence applications. (cdc.gov)
  • Of the 192 cases for which this information was available, 17 (8.9%) have received a liver transplant. (cdc.gov)
  • Intravenous N-acetylcysteine improves transplant-free survival in early stage non-acetaminophen acute liver failure. (intramed.net)
  • Another 23 experienced adverse events and 2 progressed to liver transplant. (the-hospitalist.org)
  • But it's damage that can kill or require a liver transplant, damage that frustrated liver specialists insist should be avoidable. (natap.org)
  • Over six years, researchers tracked 662 patients in acute liver failure who were treated at 22 transplant centers. (natap.org)
  • More than 900 children and teens with a wide range of liver diseases, from acute hepatitis to a chronic liver disease that may require transplant, are receiving ongoing care in our clinics. (childrensmercy.org)
  • We also coordinate with hepatology and transplant teams at the University of Kansas Medical Center to offer comprehensive care as our teenage patients transition to adulthood. (childrensmercy.org)
  • That's when his liver began to fail, eventually leading to the need for a liver transplant at Children's Mercy. (childrensmercy.org)
  • A liver transplant at Children's Mercy Kansas City has helped him get healthy and stay that way. (childrensmercy.org)
  • Marissa Ebbing has had a lot to overcome in her young life--prematurity, liver cancer, and then a liver transplant. (childrensmercy.org)
  • If you develop liver failure, you may be considered for a liver transplant . (medlineplus.gov)
  • A liver transplant is the only cure in some cases of liver failure. (medlineplus.gov)
  • Much-Needed Guidance Arrives on Drug-Induced Liver Injury Dr Nancy Reau speaks with Dr Robert Fontana, the co-author of recent guidance from the AASLD on how to diagnose and manage the harmful consequences of certain drugs and unregulated supplements. (medscape.com)
  • Drug-Induced Liver Injury: 5 Things to Know A guide to drug-induced liver injury--difficult to predict and challenging to recognize, and often with a bewildering range of presentations. (medscape.com)
  • LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. (nih.gov)
  • Causes, clinical features, and outcomes from a prospective study of drug-induced liver injury in the United States. (intramed.net)
  • 23. Björnsson E, Olsson R. Outcome and prognostic markers in severe drug-induced liver disease. (intramed.net)
  • 11] In addition, a minority of patients with fulminant hepatic failure from various causes, such as drug-induced liver damage and hepatitis A and B, are reported to have transiently detectable levels of serum antimitochondrial antibody that disappear within one year. (medscape.com)
  • We studied the pharmacokinetics of meropenem in critically ill patients with ACLF during continuous veno-venous hemodialysis (CVVHD) and compared it to critically ill patients without concomitant liver failure (NLF). (springeropen.com)
  • Concerning hepatic insufficiency, only PK and pharmacodynamic data from patients with stable alcoholic cirrhosis are available [ 11 ], but to date, there are no available data in patients suffering from ACLF with multiorgan failure. (springeropen.com)
  • Patients were grouped according to liver function as follows: patients with ACLF and patients without ACLF ("no liver failure", NLF). (springeropen.com)
  • Dr Vlad Ratziu, professor of hepatology at the Sorbonne Université, shares his thoughts on why treatments for fatty liver disease continue to fall short, in a conversation with Dr Nancy Reau. (medscape.com)
  • Acute liver failure is the appearance of severe complications rapidly after the first signs (such as jaundice) of liver disease, and indicates that the liver has sustained severe damage (loss of function of 80-90% of liver cells). (wikipedia.org)
  • The main features of acute liver failure are rapid-onset jaundice, weakness, and eventually, changes in mental status that can begin as mild confusion but progress to coma, known as hepatic encephalopathy. (wikipedia.org)
  • Since licensure, rare case reports of serum enzyme elevations without jaundice arising within 4 weeks of starting varenicline have been published, but largely in patients with other causes of liver injury (alcoholic liver disease, hepatitis C). The injury was self-limited in course and not associated with immunoallergic or autoimmune features. (nih.gov)
  • We conducted a descriptive study from April to October 2015 in 10 tertiary care hospitals throughout Pakistan to determine maternal and fetal morbidity and mortality in HEV-positive pregnant women with acute jaundice or raised liver function tests. (who.int)
  • The few reported cases of HEV during pregnancy in industrialized countries ( 2 - 5 ) mainly relate to acute genotype 3 infection. (cdc.gov)
  • Where the data on infection among cirrhotics is scanty, this study aimed to determine the frequency, microbiological spectrum and various risk factors of infections in cirrhosis of liver. (scirp.org)
  • Infection with hepatitis A virus (HAV) occasionally leads to acute liver failure and has a higher fatality rate in patients with chronic hepatitis C virus (HCV). (unboundmedicine.com)
  • The acute and chronic consequences of hepatitis B virus (HBV) infection are major health problems in the United States. (cdc.gov)
  • Preventing HBV transmission during early childhood is important because of the high likelihood of chronic HBV infection and chronic liver disease that occurs when children less than 5 years of age become infected (3). (cdc.gov)
  • Infants who become infected by perinatal transmission have a 90% risk of chronic infection, and up to 25% will die of chronic liver disease as adults (9). (cdc.gov)
  • Hepatitis B is irritation and swelling (inflammation) of the liver due to infection with the hepatitis B virus (HBV). (medlineplus.gov)
  • Guideline] Lee WM, Stravitz RT, Larson AM. Introduction to the revised American Association for the Study of Liver Diseases Position Paper on acute liver failure 2011. (medscape.com)
  • 5 Liver-Saving Strategies for the New Year Although the holidays can wreak havoc on the liver, patients can use simple interventions to modify their risk for the most common life-threatening liver diseases. (medscape.com)
  • Essentials Liver diseases are associated with profound hemostatic changes proportional to severity of illness. (nih.gov)
  • Thus, the gut microbiome might play a major part in the development of liver diseases. (ku.dk)
  • Hemodynamic parameters also were comparable, with a mean HVPG of about 19, Dr. Kainth said at the annual meeting of the American Association for the Study of Liver Diseases. (the-hospitalist.org)
  • As liver diseases (LDs) occur as liver damage takes place, their causes are variable and mostly caused by viruses and alcohol intake. (bvsalud.org)
  • There is a tendency towards stability in cases of mortality and hospitalization due to liver diseases in the Western Amazonia. (bvsalud.org)
  • This study was carried out to identify the mortality and hospitalization due to liver diseases, discover its possible causes, and identify health actions that influence the conditions and the improvement of quality of life of individuals in the region studied. (bvsalud.org)
  • Creating means and strategies aimed at health promotion and prevention can contribute to the awareness of professionals and the population and guarantee better results in the conditions of prognosis and treatment of patients affected by liver diseases, ensuring the quality of life and lower rates of morbidity and mortality. (bvsalud.org)
  • Méndez-Sánches (2005) 7 says that in 2050, approximately 2 million cases of chronic liver diseases (CLD) will be diagnosed, with alcohol still being the most frequent cause of these diseases, followed by non-alcoholic fatty liver diseases (NAFLD). (bvsalud.org)
  • Concerning Alcoholic Liver Diseases (ALD), for example, individuals' alcohol intake is the main factor of its cause, in addition to other environmental and genetic factors, such as age, weight, use of illicit drugs, and other concomitant infections 8 . (bvsalud.org)
  • Numerous treatment strategies for acute liver failure simply prevent complications and decelerate disease progression. (springer.com)
  • The more you understand about primary immunodeficiency (PI), the better you can live with the disease or support others in your life with PI. (primaryimmune.org)
  • Bariatric surgery is often the treatment of last resort, but considering it earlier may be just what patients with fatty liver disease need. (medscape.com)
  • She had no history of liver disease, alcohol abuse, risk factors for viral hepatitis or drug allergies. (nih.gov)
  • On examination, she was jaundiced but had no signs of chronic liver disease. (nih.gov)
  • The most potent risk factor in the development of alcoholic liver disease is alcohol consumption. (wikidoc.org)
  • 1996). "Prediction of risk of liver disease by alcohol intake, sex, and age: a prospective population study" . (wikidoc.org)
  • Molecular pathogenesis of alpha-1-antitrypsin deficiency-associated liver disease: A meeting review. (thieme-connect.de)
  • Systematic review: acute liver failure - one disease, more than 40 definitions. (intramed.net)
  • 19. Myers RP, Shaheen AAM, Li B, Dean S, Quan H. Impact of liver disease, alcohol abuse, and unintentional ingestions on the outcomes of acetaminophen overdose. (intramed.net)
  • Mean Model for End-Stage Liver Disease (MELD) scores were about 25. (the-hospitalist.org)
  • Patients with acute on chronic kidney disease fared the worst. (the-hospitalist.org)
  • Seminars in Liver Disease, 28, 26-42. (scirp.org)
  • Digestive and Liver Disease, 33, 41-48. (scirp.org)
  • The Sheila Sherlock Liver Centre, based at the Royal Free Hospital, is one of the UK's leading centres for treating liver disease and has been established for more than 50 years. (royalfree.nhs.uk)
  • Advanced Liver Disease Study Group. (jptcp.com)
  • The model for end-stage liver disease (MELD). (jptcp.com)
  • Clinical Liver Disease. (mssm.edu)
  • Primary biliary cirrhosis (PBC) is a progressive inflammatory liver disease characterized by autoimmune-mediated destruction of intrahepatic bile ducts. (medscape.com)
  • The Liver Care Center is designed to provide a medical home for children dealing with highly complex liver disease. (childrensmercy.org)
  • Our team of liver specialists is committed to providing comprehensive care by partnering with families to care for each child - not just the disease. (childrensmercy.org)
  • Development and validation of machine learning models for nonalcoholic fatty liver disease. (cdc.gov)
  • Predisposing factors for acetaminophen -induced liver failure include preexisting liver disease, chronic alcohol use, and use of drugs that induce the cytochrome P-450 enzyme system (eg, anticonvulsants). (msdmanuals.com)
  • each year approximately 4,000-5,000 of these persons die from chronic liver disease (1). (cdc.gov)
  • This document provides the rationale for a comprehensive strategy to eliminate transmission of HBV and ultimately reduce the incidence of hepatitis B and hepatitis B-associated chronic liver disease in the United States. (cdc.gov)
  • ABSTRACT The aim of the study was to determine the prevalence of anti-hepatitis A virus (anti-HAV) antibodies among 172 children with chronic liver disease, and to calculate the cost- effectiveness of prescreening prior to hepatitis A vaccination. (who.int)
  • 101 with CLD and 71 healthy age- and sex- discussed the outcome of acute hepatitis matched brothers, sisters and contacts of the A in patients with chronic liver disease patients as a control group. (who.int)
  • Because some patients develop asymptomatic disease until liver compensation, understanding the real numbers of chronic liver disease (CLD) cases may not be reliable 3 . (bvsalud.org)
  • Age, gender, tumour characteristics, BCLC classification, Child-Pugh stage, pre-existing liver disease, treatment, survival, frequency of HCC surveillance and reasons for surveillance failures were retrospectively determined in 616 patients diagnosed with HCC at Karolinska University Hospital 2005-2012. (medscape.com)
  • Hepatitis C, alcoholic liver disease and non-alcoholic fatty liver disease (NAFLD) were the most common diagnoses. (medscape.com)
  • In 35% of cases, surveillance was missed due to doctor's failure to order surveillance or to diagnose the underlying liver disease. (medscape.com)
  • Diagnosis of NAFLD or alcoholic liver disease increased the risk of not receiving surveillance more than two-fold. (medscape.com)
  • Undiagnosed liver disease was most common in NAFLD patients. (medscape.com)
  • NAFLD and alcoholic liver disease were associated with deficient surveillance. (medscape.com)
  • Out of eleven hundred and forty-one patients with cirrhosis of liver, four hundred and ninety (42.94%) patients had infections. (scirp.org)
  • The risk factors for bacterial infections among patients with cirrhosis of liver were upper gastrointestinal bleeding (odd ratio = 4.57, p = 0.0001), use of proton pump inhibitors (odd ratio = 2.57, p = 0.0001), degree of malnutrition (odd ratio = 10.34, p = 0.0001) and severity of cirrhosis (odd ratio = 12.99, p = 0.000). (scirp.org)
  • All types of infections occurred with varying frequency in cirrhosis of liver. (scirp.org)
  • Varenicline has been associated with a low rate of serum enzyme elevations during therapy and, since approval and its widescale use, with rare instances of clinically apparent mild liver injury. (nih.gov)
  • C (probable rare cause of clinically apparent liver injury). (nih.gov)
  • The mechanism by which varenicline might cause liver injury is not known. (nih.gov)
  • Warfarin therapy is associated with rare instances of idiosyncratic, clinically apparent liver injury that are usually mild and rapidly reversible on stopping. (nih.gov)
  • Liver injury due to warfarin therapy is rare, but clinically apparent acute liver injury attributable to it has been reported. (nih.gov)
  • Liver injury is more common with other coumarin derivatives such as phenprocoumon and acenocoumarol, which are available in other countries but not in the United States. (nih.gov)
  • The typical case of acute liver injury arises within 3 to 8 weeks of starting warfarin, although rare instances of liver injury arising after months or years of therapy have been reported (and these long latencies are common with phenprocoumon hepatotoxicity). (nih.gov)
  • 24. Lescot T, Karvellas C, Beaussier M, Magder S. Acquired liver injury in the intensive care unit. (intramed.net)
  • In vivo , Pts treatment effectively protected against APAP-induced severe liver injury by decreasing the lethality rate, the serum alanine transaminase (ALT) and aspartate aminotransferase (AST) levels, liver histological injury, liver malondialdehyde (MDA) formation and myeloperoxidase (MPO) levels and by increasing liver glutathione (GSH) and superoxide dismutase (SOD) levels. (karger.com)
  • Liver Injury Caused by Drugs Many medications (eg, statins) commonly cause asymptomatic elevation of hepatic enzymes (alanine aminotransferase [ALT], aspartate aminotransferase [AST], alkaline phosphatase). (msdmanuals.com)
  • Analyses of syndromic surveillance data did not indicate recent increases in pediatric hepatitis-associated ED visits or hospitalizations, liver transplants, or adenovirus type 40 or 41 percent positivity among US children, compared with pre-COVID-19 pandemic levels. (cdc.gov)
  • reported a reduction in hospital admissions and liver transplants for acetaminophen overdose, but conflicting findings regarding the severity of poisonings, deaths, and over the counter sales following this legislation[ 11 ]. (biomedcentral.com)
  • Among recipients of liver transplants for end-stage primary biliary cirrhosis, the serum antimitochondrial antibody level can decrease slightly and elevate back to pretransplant levels in the first year posttransplant. (medscape.com)
  • Born with a rare liver disorder called biliary atresia, Cambree Alvarez required not one, but two liver transplants at Children's Mercy before her second birthday. (childrensmercy.org)
  • We present a case of acute impending liver failure in an adolescent male using a weight-loss product containing green tea extract. (wjgnet.com)
  • Because of the high rate of severe acute hepatitis E reported in pregnant women in developing countries, we monitored the patient for negative outcomes during gestation but found none. (cdc.gov)
  • Lee wants to copy Britain, which say a 30% drop in severe liver poisonings after restricting how much acetaminophen could be bought at once. (natap.org)
  • Acute hepatitis, unless severe, needs no treatment. (medlineplus.gov)
  • Severe liver damage or cirrhosis can be caused by hepatitis B. (medlineplus.gov)
  • Prof. Vinay Sundaram, Associate Professor of Medicine and Director of Hepatology Outcomes Research at Cedars-Sinai Medical Center, passed away on July 14, 2022. (easl.eu)
  • Heart failure (signs and symptoms, diagnosis) 4. (muni.cz)
  • Oral anticoagulation is also used to prevent arterial or venous embolization after acute myocardial infarction, atrial fibrillation and prosthetic heart value placement. (nih.gov)
  • Acute myocardial infarction and the complications 17. (muni.cz)
  • Treatment of acute myocardial infarction 18. (muni.cz)
  • 2004) Antibiotic Prophylaxis after Endoscopic Therapy Prevents Rebleeding in Acute Variceal Hemorrhage: A Randomized Trial. (scirp.org)
  • 1. Prediction of the first variceal hemorrhage in patients with cirrhosis of the liver and esophageal varices. (jptcp.com)
  • Severity of hepatotoxicity after a single acute overdose is predicted by serum. (msdmanuals.com)
  • Acetaminophen overdose typically has a good prognosis, even if hepatic failure has developed. (biomedcentral.com)
  • Use it correctly and acetaminophen, best known by the Tylenol brand, lives up to its reputation as one of the safest painkillers. (natap.org)
  • The Food and Drug Administration has long wrestled with the liver risk, warning two years ago that more than 56,000 emergency-room visits a year are due to acetaminophen overdoses and that 100 people die annually from unintentionally taking too much. (natap.org)
  • More remarkable was the steady increase: Acetaminophen was to blame for 28% of the liver poisonings in 1998, but caused 51% of cases in 2003. (natap.org)
  • While FDA runs a consumer education campaign about the liver risk, nonprescription drugs chief Dr. Charles Ganley says the new study suggests the agency may need to further target narcotic-acetaminophen combinations. (natap.org)
  • Acetaminophen metabolism occurs primarily in the liver and is illustrated in the image below. (medscape.com)
  • The Rumack-Matthew nomogram interprets the acetaminophen concentration (in micrograms per mL), in relation to time (in hours) after ingestion, and is predictive of possible hepatotoxicity after single, acute ingestions of acetaminophen. (medscape.com)
  • This often contributes towards multi organ failure. (wikipedia.org)
  • The liver, as the first organ to encounter microbial products that cross the gut epithelial barrier, is affected by the gut microbiome in many ways. (ku.dk)
  • Cody was able to save many lives through his generosity as an organ and tissue donor. (donors1.org)
  • Liver Structure and Function The liver is a metabolically complex organ. (msdmanuals.com)
  • Kidney failure is common, present in more than 50% of ALF patients, either due to original insult such as paracetamol resulting in acute tubular necrosis or from hyperdynamic circulation leading to hepatorenal syndrome or functional kidney failure. (wikipedia.org)
  • Acute liver failure is a life-threatening clinical syndrome characterized by rapid development of hepatocellular necrosis leading to high mortality and resource costs. (springer.com)
  • Acute liver failure (ALF) is a life-threatening clinical syndrome characterized by rapid hepatocellular necrosis due to various acute injuries induced by hepatotoxic drugs, immune-mediated attack, or viral infections. (springer.com)
  • Acute coronary syndrome 27. (muni.cz)
  • The pattern of liver enzyme elevations is typically cholestatic, but hepatocellular and mixed patterns have also been reported. (nih.gov)
  • Hepatocellular Carcinoma: 5 Things to Know Get up to speed on the latest data surrounding the most common form of liver cancer. (medscape.com)
  • Predictors of early re-bleeding and mortality after acute variceal haemorrhage in patients with cirrhosis. (jptcp.com)