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These were imputed alongside published data to obtain diploid genotypes from more than 1,600 ancient humans. (lu.se)
Given visually complex social relationships, humans presumably have always observed and speculated about the physical differences among individuals and groups. (daynal.org)

372 donors were genotyped using a custom precision medicine single nucleotide polymorphism (SNP) microarray. (nature.com)
After attributing a regional and/or continental ancestry to each individual using genome-wide polymorphism data, we are able to capture the effect of different environmental exposures on gene expression and health-related traits, while simultaneously controlling for genetic relatedness and migration. (nature.com)
ADH1C genotyping was performed by PCR-based restriction fragment length polymorphism (PCR-RFLP) analysis from whole blood. (uni-luebeck.de)
METHODS: The PADI4_94 (rs2240340) single nucleotide polymorphism (SNP) was directly genotyped in a cohort of unrelated UK Caucasian patients with RA (n=3732) and population controls (n=3039). (ox.ac.uk)
Genotypes included genome-wide single-nucleotide polymorphism (SNP) data utilizing the Affymetrix 6.0 array with imputation to 2.5 million HapMap SNPs and candidate gene SNP data utilizing a 50K cardiovascular gene-centric array (ITMAT-Broad-CARe [IBC] array). (ox.ac.uk)
The polymorphism was present as an insertion in cells derived from a group of Japanese individuals, but was completely absent (a deletion) in others, albeit with a lower frequency (hence called the minor allele). (fatsoflife.com)
METHODOLOGY: Lead single nucleotide polymorphism (SNPs) at 37 T2D-risk loci attaining genome-wide significance in Europeans were genotyped in 878 T2D cases and 1523 normoglycaemic controls from Sri Lanka. (ox.ac.uk)
As amplified fragment length polymorphism (AFLP) markers are discovered and genotyped as the samples are assayed, this type of marker is free of ascertainment bias. (biomedcentral.com)
The CYP19 tetranucleotide TTTA repeat polymorphism was genotyped with a protocol of PCR and fluorescent capillary electrophoresis. (nel.edu)
The most common allele of the tetranucleotide TTTA repeat polymorphism in the forth intron of CYP19 gene in Han Chinese women is 11R, which was different with the previous study in European Caucasians. (nel.edu)
Here we obtained a well-resolved polymorphism type of intergenic spacer (IGS) sequence phylogeny of B. burgdorferi sensu stricto clonal complexes (corresponding to the ospC- A and -B groups) is associated by using multilocus sequence typing at housekeeping loci with hematogenous dissemination in patients with early as well as loci under adaptive evolution. (cdc.gov)

We report a genome-wide association study meta-analysis of ∼2.5 million directly genotyped or imputed SNPs with alcohol consumption (gram per day per kilogram body weight) among 12 population-based samples of European ancestry, comprising 26,316 individuals, with replication genotyping in an additional 21,185 individuals. (ox.ac.uk)
The 93 SNP AIM subset had substantially larger intercontinental paired Fst values than the random SNPs for any of the pairs of population groups from the sub-Saharan African, Amerindian, East Asian, Oceana and European (excluding the South Asian populations) continental groups (Table 1). (familytreedna.com)
A small number of candidate gene SNPs reveal continental ancestry in African Americans. (icompbio.net)
Using genetic data from an obesity candidate gene study of self-reported African Americans and European Americans, we investigated the number of Ancestry Informative Markers (AIMs) and candidate gene SNPs necessary to infer continental ancestry. (icompbio.net)
We detail the development of the ancestry informative single nucleotide polymorphisms (SNPs) panel forming part of the VISAGE Basic Tool (BT), which combines 41 appearance predictive SNPs and 112 ancestry predictive SNPs (three SNPs shared between sets) in one massively parallel sequencing (MPS) multiplex, whereas blood-based age analysis using methylation markers is run in a parallel MPS analysis pipeline. (gmi.tirol)
The selection of SNPs for the BT ancestry panel focused on established forensic markers that already have a proven track record of good sequencing performance in MPS, and the overall SNP multiplex scale closely matched that of existing forensic MPS assays. (gmi.tirol)
SNPs were chosen to differentiate individuals from the five main continental population groups of Africa, Europe, East Asia, America, and Oceania, extended to include differentiation of individuals from South Asia. (gmi.tirol)
The differentiation power of the component ancestry SNPs of BT was balanced as far as possible to avoid bias in the estimation of co-ancestry proportions in individuals with admixed backgrounds. (gmi.tirol)
Comparisons were made of the African, European, and Native American estimated co-ancestry proportions in the six admixed 1000 Genomes populations, using the BT ancestry panel SNPs and 572,000 Affymetrix Human Origins array SNPs. (gmi.tirol)
Very similar co-ancestry proportions were observed down to a minimum value of 10%, below which, low-level co-ancestry was not always reliably detected by BT SNPs. (gmi.tirol)
We report a meta-analysis of four large genome-wide association studies of CAD, with ∼575,000 genotyped SNPs in a discovery dataset comprising 15,420 individuals with CAD (cases) (8,424 Europeans and 6,996 South Asians) and 15,062 controls. (ox.ac.uk)
To demonstrate its capabilities, we compared the FST distributions of GenoChip SNPs to those of two commercial arrays for three continental populations. (blogspot.com)

Among people of European descent, GWASs have identified genetic variants at 13 loci that are associated with blood pressure. (ox.ac.uk)
Interactions of dietary whole-grain intake with fasting glucose- and insulin-related genetic loci in individuals of European descent: a meta-analysis of 14 cohort studies. (ox.ac.uk)
RESEARCH DESIGN AND METHODS: Via meta-analysis of data from 14 cohorts comprising ∼ 48,000 participants of European descent, we studied interactions of whole-grain intake with loci previously associated in GWAS with fasting glucose (16 loci) and/or insulin (2 loci) concentrations. (ox.ac.uk)
Therefore, we tested whether the aggregate effect of these loci is diminished in adults of European ancestry reporting high levels of physical activity. (lu.se)
Twelve obesity-susceptibility loci were genotyped or imputed in 111,421 participants. (lu.se)
Owing to the region's extreme gene density, the multiplicity of disease-associated alleles, strong associations between alleles, limited genotyping capability, and inadequate statistical approaches and sample sizes, which, and how many, loci within the MHC determine susceptibility remains unclear. (ox.ac.uk)
In stage 2, the top 85 loci from stage 1 were genotyped in 1,264 cases and 1,222 controls. (ox.ac.uk)
To resolve phylogenetic relationships among ries of bacterial clonal complexes by using concatenated isolates, we sequenced 68 isolates from Europe and North sequences of housekeeping genes when within-loci and America at 1 chromosomal locus (16S-23S ribosomal RNA between-loci recombinations are infrequent ( 5 ). (cdc.gov)
A genome-wide association study in Europeans and South Asians identifies five new loci for coronary artery disease. (ox.ac.uk)

Therefore, we conducted high-density genome-wide association studies for sleep duration in seven European populations (N=4251). (ox.ac.uk)
However, studies in European populations have produced conflicting results. (ox.ac.uk)
CONCLUSION: In the largest study performed to date, the PADI4 genotype was not a significant risk factor for RA in people of European ancestry, in contrast to Asian populations. (ox.ac.uk)
The population frequency of the indel (rs66698963) is remarkably different among human populations with the insertion being far more frequent in South Asians, Africans and some East Asian populations, and far less common in European and other East Asian populations. (fatsoflife.com)
They didn't claim to be able to differentiate ethnic/geographic populations within Europe. (familytreedna.com)
Finally, the ancestral information is potentially useful, since recent papers have shown that multi-100K SNP genome-wide testing can produce fine-scale ancestral inference, even in relative homogeneous populations such as Europeans. (blogspot.com)
However, as of this writing, you won't get this type of information, but rather a simple 4-group global admixture estimate, as well as a measure of your similarity to the Human Genome Diversity Panel populations. (blogspot.com)
Here, we employ forward simulation, guided by empirical deep resequencing data, to model the genetic architecture of quantitative polygenic traits in both the general European and the Finnish populations simultaneously. (ox.ac.uk)
and 167 samples of six populations from in-house genotyping of individuals from Middle East, North and East African regions complementing those of the sampling regimes of the other diversity projects. (gmi.tirol)
The term race refers to the concept of dividing people into populations or groups on the basis of various sets of characteristics and beliefs about common ancestry. (daynal.org)
The African continent is home to 1.2 billion people, 17% of the world's population, and a large proportion of human genetic diversity and yet African populations are relatively under-studied with only 3% of Genome-Wide Association Study (GWAS) samples coming from African ancestries (1), mostly African Americans. (madcapnetwork.org)
Polygenic Risk Scores for prostate cancer have been developed by European and Asian studies but they do not work as well in African populations for several reasons. (madcapnetwork.org)
For example, European and Asian studies miss many alleles that are present in African populations due to the much greater genetic diversity in Africa. (madcapnetwork.org)
Combining data from genome-wide association studies (GWAS) conducted at different locations, using genotype imputation and fixed-effects meta-analysis, has been a powerful approach for dissecting complex disease genetics in populations of European ancestry. (ox.ac.uk)
While the Argentinean and Brazilian national populations have roughly the same degree of pre-1500 European ancestry, Argentine has a White European national image while Brazil has a multiracial one. (humanvarieties.org)
Across the Americas, Amerindian and African (versus European) ancestry was found to be negatively correlated in admixed populations (e.g. (humanvarieties.org)
All of these variants have been discovered in European populations. (ox.ac.uk)

These data are publicly-available to enable genotype-specific sample requests and the study of novel genotype:phenotype associations, aiding in the mission of nPOD to enhance understanding of diabetes pathogenesis to promote the development of novel therapies. (nature.com)
Referenced article focusing on the relationship between phenotype and genotype. (cancerindex.org)

We developed a framework for inference of germline variants from tumor panel sequencing, including imputation, quality control, inference of genetic ancestry, germline polygenic risk scores, and HLA alleles. (biomedcentral.com)

The goal of this study was to analyze the effect of ethnicity and genetic ancestry on observed disease prevalence and predicted disease risk in Colombia. (frontiersin.org)
Population distributions of Colombia's three major ethnic groups - Mestizo, Afro-Colombian, and Indigenous - were compared to disease prevalence and socioeconomic indicators. (frontiersin.org)
Disease prevalence co-varies across geographic regions, consistent with the regional distribution of ethnic groups. (frontiersin.org)
Patterns of genetic ancestry and admixture for a cohort of 624 individuals from Medellín were compared to disease risk inferred via polygenic risk scores (PRS). (frontiersin.org)
African genetic ancestry is most strongly correlated with predicted disease risk, whereas European and Native American ancestry show weaker effects. (frontiersin.org)
African ancestry is mostly positively correlated with disease risk, and European ancestry is mostly negatively correlated. (frontiersin.org)
The relationships between ethnicity and disease prevalence do not show an overall correspondence with the relationships between ancestry and disease risk. (frontiersin.org)

Your family medical history and lifestyle are much more likely to affect your health than the common variants genotyped in the current generation of microarrays. (blogspot.com)
It's useful to think about whole-genome genotyping arrays as a combination of content "modules" that, together, form the total set of variants genotyped by the array. (madcapnetwork.org)

This study aims to establish whether common variants conferring T2D-risk in Europeans contribute to T2D-susceptibility in the South Asian population of Sri Lanka. (ox.ac.uk)

Further, in order to capture gene-by-environment interactions through eQTL analyses, we combine whole-transcriptome RNA-Sequencing profiles with whole-genome genotyping and extensive fine-scale environmental exposure data. (nature.com)

Our meta-analysis of 32 studies in 66,240 individuals of European ancestry was based on the custom ∼50,000 SNP genotyping array (the ITMAT-Broad-CARe array) covering ∼2,000 candidate genes. (ox.ac.uk)
The explained phenotypic variance from this approach was comparable to that from a meta-analysis of GWAS data, suggesting that a focused genotyping approach can further increase the understanding of heritability of plasma lipids. (ox.ac.uk)
Meta-analysis of previously published studies and our data confirmed no significant association between the PADI4_94 genotype and RA in people of European descent (OR 1.06, 95% CI 0.99 to 1.13, p=0.12). (ox.ac.uk)

With this in mind, the MADCaP team designed a GWAS strategy to genotype the maximum number of African variants across all 6,000 available samples within the budget available. (madcapnetwork.org)

Conclusions: In a white population, MCV values were not associated with genotype polymorphisms of ADH1C. (uni-luebeck.de)
METHODS: The PvuII and XbaI polymorphisms were genotyped in 3,893 women participants of the Rotterdam Study. (ox.ac.uk)

If your family is Puerto Rican it is not at all unusual to have African ancestry, African ancestry on numerous lines, no family phenotypes that seem African in appearance, and no records identifying admixture events. (familytreedna.com)
AncestryDNA, 23andMe, FamilyTreeDNA Family Finder and Genographic2.0 all offer much more reliable ancestry admixture assays than AbDNA. (familytreedna.com)
These data provide additional support for using the 93 AIM set to efficiently identify continental subject groups for genetic studies, to identify study population outliers, and to control for admixture in association studies. (familytreedna.com)
Previously, a literature review was conducted regarding continental racial admixture and educational attainment and/or socioeconomic status. (humanvarieties.org)
Some of these predict that the ancestry-outcome association will generalize spatially, such that admixture will be correlated with outcomes across regions and nations. (humanvarieties.org)
The association between regional ancestral and cognitive related outcome variation in Mexico will first be explored, since for this county reliable regional admixture estimates, at least with regards to European and Amerindian ancestry, and outcome measures are available and also since there is a good deal of spatial variation in admixture (and outcomes). (humanvarieties.org)
2014). For the two sources, Pearson correlation was 0.94 for European admixture, -0.60 for African Admixture, and 0.94 for Amerindian admixture. (humanvarieties.org)
Regarding European and Amerindian admixture, the estimates exhibited a high reliability, thus justifying their combination. (humanvarieties.org)

Proportions of African and European ancestry were assessed with STRUCTURE (K 2), using 276 AIMs. (icompbio.net)
In unsupervised analyses, a Sardinian-specific ancestry component correlates with shared drift parameters with both the Neolithic farmers and Paleolithic hunter-gatherers, and is consistent with supervised estimates of ancestry proportions in which the Ogliastra individuals have higher Neolithic farmer and Paleolithic hunter-gatherer ancestries, while individuals from the rest of the island show an infusion of the pastoralist ancestry. (blogspot.com)
RESULTS: Baseline characteristics were similar in the Latino and non-Latino groups, although higher proportions of Latino patients were 40 years of age or younger, had a body-mass index (BMI, the weight in kilograms divided by the square of the height in meters) of more than 27 or more than 30, and had cirrhosis. (johnshopkins.edu)

Model-based clustering and ancestry informative markers analyses suggested that this is due to taurine introgression. (biomedcentral.com)
CoAIMs: A Cost-Effective Panel of Ancestry Informative Markers for Determining Continental Origins. (coriell.org)

We conducted logistic regression analyses to assess the risk of breast cancer by each of the ESR1 genotypes. (ox.ac.uk)
The logistic regression analyses showed no difference in risk for postmenopausal breast cancer in carriers of the PvuII or XbaI genotypes neither in overall, incident or prevalent cases. (ox.ac.uk)
There was little evidence for ancestry-specific associations, supporting the use of combined analyses. (ox.ac.uk)

CONCLUSION: Our data indicate that most T2D-risk variants identified in Europeans have similar effects in South Asians from Sri Lanka, and that systematic difference in common variant associations are unlikely to explain inter-ethnic differences in prevalence or presentation of T2D. (ox.ac.uk)

In this work, we assess the utility of discarded, off-target reads from tumor-only panel sequencing for the recovery of genome-wide germline genotypes through imputation. (biomedcentral.com)

From ∼ 1000 individuals of a founder population in Quebec, we reveal a substantial impact of the environment on the transcriptome and clinical endophenotypes, overpowering that of genetic ancestry. (nature.com)
Drawing from this founding population of individuals with largely French ancestry, we selected 1007 individuals to determine mechanisms by which genomes, the environment, and their interactions contribute to phenotypic variation. (nature.com)
RESEARCH DESIGN AND METHODS: We tested the association between FTO genotype and 10 metabolic traits using data from 17,037 white European individuals. (ox.ac.uk)
Gene × physical activity interactions in obesity: combined analysis of 111,421 individuals of European ancestry. (lu.se)
INTRODUCTION: Most studies seeking common variant associations with type 2 diabetes (T2D) have focused on individuals of European ancestry. (ox.ac.uk)
Yamnaya groups later admixed with individuals associated with the Globular Amphora culture before expanding into Europe. (lu.se)

METHODS: In this study, we attempted to replicate the association between rs75932628 and AD risk by directly genotyping rs75932628 in 2 independent Caucasian family cohorts consisting of 927 families (with 1,777 affected and 1,235 unaffected) and in 2 Caucasian case-control cohorts composed of 1,314 cases and 1,609 controls. (mdc-berlin.de)
In addition, we imputed genotypes in 3 independent Caucasian case-control cohorts containing 1,906 cases and 1,503 controls. (mdc-berlin.de)
PADI4 genotype is not associated with rheumatoid arthritis in a large UK Caucasian population. (ox.ac.uk)
This study explored the association of the PADI4 genotype with RA in a large UK Caucasian population. (ox.ac.uk)

In order to obtain unbiased assessments of genetic differentiation and structure in taurine and zebu cattle, we analyzed a dataset of 135 AFLP markers in 1,593 samples from 13 zebu and 58 taurine breeds, representing nine continental areas. (biomedcentral.com)
Although many commercial arrays exist for genome-wide SNP genotyping, they were designed for medical genetic studies and contain medically related markers that are not appropriate for global population genetic studies. (blogspot.com)

Germline variation at 8q24 and prostate cancer risk in men of European ancestry. (ox.ac.uk)
Here we combine genetic data across the 8q24 susceptibility region from 71,535 prostate cancer cases and 52,935 controls of European ancestry to define the overall contribution of germline variation at 8q24 to prostate cancer risk. (ox.ac.uk)

Currently, the vast majority of genomic research cohorts are made up of participants with European ancestry. (frontiersin.org)
The population frequency of the allele corresponding to the rs66698963 insertion (allele named I) or deletion (allele named D) was determined from genomic DNA extracted from human samples (blood, breast milk, and placenta) obtained from several participating institutions in the US and Canada (n=211, nearly all from Kansas City), as well as from a group of Asian Indians (n=76). (fatsoflife.com)
Dr. Joseph Lachance, of Georgia Institute of Technology, USA, is co-chair of the MADCaP Genomic Working Group. (madcapnetwork.org)
Four ospC clonal complexes dence of genetic endemism, recent migration events, and (A, B, I, and K groups) were found to be more likely than recombinant genomic types. (cdc.gov)
It has been noted that in the Americas racial identification and genomic racial ancestry frequently don't well correspond. (humanvarieties.org)
2014) found a correlation of 0.48 between self-identified European and Amerindian racial identity and genomic ancestry in a five country sample. (humanvarieties.org)
For example: To what degree are differences in national racial identification related to such and such outcomes independent of genomic ancestry? (humanvarieties.org)
these include: national genomic percents, aggregate self- identified race percents, Putterman's ancestry percents, and national skin reflectance scores. (humanvarieties.org)

The top IBC association for SBP was rs2012318 (P= 6.4 × 10(-6)) near SLC25A42 and for DBP was rs2523586 (P= 1.3 × 10(-6)) near HLA-B. None of the top variants replicated in additional AA (n = 11 882) or European-American (n = 69 899) cohorts. (ox.ac.uk)
However, a statistically significant interaction effect was only apparent in North American cohorts (n = 39,810, Pinteraction = 0.014 vs. n = 71,611, Pinteraction = 0.275 for Europeans). (lu.se)

Allelic odds ratios and risk allele frequencies in Sri Lankan subjects were not systematically different to those reported in Europeans. (ox.ac.uk)

in a fixed number of samples, however, genotyping arrays miss a substantial portion of genetic signals detected in sequencing, even in the Finnish founder population. (ox.ac.uk)

We showcase the feasibility and utility of our framework by analyzing 25,889 tumors and identifying the relationships between genetic ancestry, polygenic risk, and tumor characteristics that could not be studied with conventional on-target tumor data. (biomedcentral.com)

It is unknown if these variants confer susceptibility in people of African ancestry. (ox.ac.uk)

Here, to investigate the cross-continental effects of these migrations, we shotgun-sequenced 317 genomes-mainly from the Mesolithic and Neolithic periods-from across northern and western Eurasia. (lu.se)
From analysis of 1000 Genomes and HGDP-CEPH samples from these six population groups, the BT ancestry panel was shown to have no classification error using the Bayes likelihood calculators of the Snipper online analysis portal. (gmi.tirol)

Among African Americans, the median absolute difference from reference African ancestry values ranged from 0.01 to 0.03 for the four AIMs subsets and from 0.03 to 0.09 for the four candidate gene SNP subsets. (icompbio.net)

The boundary dissolved when Yamnaya-related ancestry spread across western Eurasia around 5,000 bp, resulting in a second major turnover that reached most parts of Europe within a 1,000-year span. (lu.se)
The genetic origin and fate of the Yamnaya have remained elusive, but we show that hunter-gatherers from the Middle Don region contributed ancestry to them. (lu.se)
In this poster he underlines the fact that the Yamnaya people from the North Caspian region did not totally vacate their homeland nor moved en masse to Western Europe, but actually left most of their descendants in the North Caspian. (blogspot.com)
OK Oleg, but almost all modern day Europeans, especially those from across Northern and Eastern Europe, do derive a lot of their ancestry from Bronze Age steppe groups closely related to the Yamnaya people of the North Caspian. (blogspot.com)
The ancient samples from the Yamnaya archaeological culture are located on this eastern branch, showing that the paternal descendants of the Yamnaya population - in contrast to the published autosomal findings - still live in the Pontic steppe and were not an important source of paternal lineages in present-day West Europeans. (blogspot.com)

Imputed data from the Wellcome Trust Case Control Consortium (WTCCC) was used to investigate the association of PADI4_94 with RA in an independent group of RA cases (n=1859) and controls (n=10 599). (ox.ac.uk)
PRACTICAL (Prostate Cancer Association Group to Investigate Cancer-Associated Alterations in the Genome) Consortium None. (ox.ac.uk)
This led the consortium to choose a genotyping microarray technology which offered high marker densities, high data quality plus the opportunity to customise the content to the study's needs. (madcapnetwork.org)

CONCLUSIONS: FTO genotype is associated with metabolic traits to an extent entirely consistent with its effect on BMI. (ox.ac.uk)

Herein describes the release of high-parameter genotyping data from this collection. (nature.com)
Data were technically validated using published algorithms to evaluate donor relatedness, ancestry, imputed HLA, and T1D genetic risk score. (nature.com)
DISCUSSION: In general, the survival analysis method used to analyze the time-to-place data as described here could be applied to a wide variety of health services and used to compare travel patterns among different groups. (cdc.gov)

By this they mean that the 93 AIM SNP panel was able to accurately separate the samples by continent - sub-Saharan African, Amerindian, East Asian, Oceana and European. (familytreedna.com)
Collecting and genotyping large samples is hampered both by strict ethics rules that publically-funded medical researchers must adhere to, and also by the actual cost of sample-collection and genotyping. (blogspot.com)

We compared the observed effect of FTO genotype on each trait to that expected given the FTO-BMI and BMI-trait associations. (ox.ac.uk)

We aimed to test whether FTO genotype is associated with variation in these metabolic traits. (ox.ac.uk)
These discoveries need to be evaluated in other major ancestral groups, to understand ethnic differences in predisposition, and establish whether these contribute to variation in T2D prevalence and presentation. (ox.ac.uk)

Air pollution impacts gene expression and pathways affecting cardio-metabolic and respiratory traits, when controlling for genetic ancestry. (nature.com)

The lack of the letter 'F' in the pre-1987 Tagalog alphabet (Abakada) caused the letter 'P' to be substituted for 'F' , though the alphabets and/or writing scripts of some non-Tagalog ethnic groups included the letter 'F'. Upon official adoption of the modern, 28-letter Filipino alphabet in 1987, the term Filipino was preferred over Pilipino . (everipedia.org)
We evaluated the effect of Latino ethnic background on the response to treatment with peginterferon alfa-2a and ribavirin in patients infected with HCV genotype 1 who had not been treated previously. (johnshopkins.edu)

Meltzer 1993) Drawing on Classical sources and upon their own internal interactions - for example, the hostility between the English and Irish was a powerful influence on early thinking about the differences between people (Takaki 1993) - Europeans began to sort themselves and others into groups associated with physical appearance and with deeply ingrained behaviors and capacities. (daynal.org)

Similarly, relatedness decreased in the west from the Neolithic transition onwards, whereas, east of the Urals, relatedness remained high until around 4,000 bp, consistent with the persistence of localized groups of hunter-gatherers. (lu.se)

Large-scale ancestry shifts occurred in the west as farming was introduced, including near-total replacement of hunter-gatherers in many areas, whereas no substantial ancestry shifts happened east of the zone during the same period. (lu.se)

BTW my AbDNA accorded me about 10% African ancestry that has never been confirmed by on four sibling genome-wide scans. (familytreedna.com)
I wonder if some of the reason for these results is the quality of the marker/s they are using for African ancestry? (familytreedna.com)
We found a geographical pattern of expected heterozygosity in European taurine breeds decreasing with the distance from the domestication centre, arguing against a large-scale introgression from European or African aurochs. (biomedcentral.com)
Medieval models of "race" mixed Classical ideas with the notion that humanity as a whole was descended from Shem , Ham and Japheth , the three sons of Noah , producing distinct Semitic ( Asian ), Hamitic ( African ), and Japhetic ( European ) peoples. (daynal.org)
The rise of the Atlantic slave trade , which gradually displaced an earlier trade in slaves from throughout the world, created a further incentive to categorize human groups in order to justify the subordination of African slaves. (daynal.org)
Prostate cancer is an excellent example of the research opportunity in Africa: it is the leading cause of cancer-related deaths in African men and, globally, has higher prevalence and worse outcomes in men of African ancestry. (madcapnetwork.org)
White European, Black African, and Amerindian - plus an "Other" group. (humanvarieties.org)

We also compare the relative power and efficiency of exome array genotyping to those of high-coverage exome sequencing. (ox.ac.uk)
Sometimes, a study's needs can be met by an existing genotyping array design. (madcapnetwork.org)
GenoChip, the Genographic Project's new genotyping array, was designed to resolve these issues and enable higher-resolution research into outstanding questions in genetic anthropology. (blogspot.com)

Anatomy1

Diseases1

Chemicals and Drugs2

Analytical, Diagnostic and Therapeutic Techniques and Equipment7

Phenomena and Processes17

Disciplines and Occupations3

Anthropology, Education, Sociology and Social Phenomena1

Humanities1

Information Science2

Named Groups10

Health Care5

Geographicals3

Humans2

Polymorphism11

SNPs12

Loci9

Populations17

Phenotype2

Alleles1

Disease7

Variants genotyped2

Common variants1

Whole-genome1

Meta-analysis3

GWAS1

Polymorphisms2

Admixture8

Proportions3

Informative markers2

Analyses3

South Asians1

Imputation1

Individuals6

Caucasian4

Markers2

Germline2

Genomic8

Cohorts2

Allelic1

Arrays1

Polygenic1

Susceptibility1

Genomes2

0.031

Yamnaya5

Consortium3

Conclusions1

Data3

Samples2

Associations1

Variation2

Traits1

Ethnic2

Interactions1

Consistent1

Hunter-gatherers1

African7

Array3