• We observed CsrS-dependent regulation of 72 of the 73 genes whose expression changed in response to elevated extracellular Mg(2+) in wild-type bacteria, a result that identifies CsrS as the principal, if not exclusive, sensor for extracellular Mg(2+) in GAS. (lu.se)
  • In addition, investigators identified multiple antimicrobial resistance genes and mutations in most Campylobacter bacteria linked to this outbreak, indicating they were resistant to many first-line antibiotics used to treat Campylobacter infections. (cdc.gov)
  • Bacterial therapy is the therapeutic use of bacteria to treat diseases. (wikipedia.org)
  • Bacterial therapeutics are living medicines, and may be wild type bacteria (often in the form of probiotics) or bacteria that have been genetically engineered to possess therapeutic properties that is injected into a patient. (wikipedia.org)
  • By contrast, metagenomic sequencing was a "single diagnostic test with precise and clear quantitative detection of clinically important species and antibiotic-resistance genes of MDR bacteria relative to the abundance of all other species and antibiotic-resistance genes within the gut microbiota. (genomeweb.com)
  • XDR Shigella strains can spread antimicrobial resistance genes to other enteric bacteria. (cdc.gov)
  • The team first optimized this plasmid for bacteria-to-yeast conjugation by deleting 55 genes or small genetic regions to create four streamlined plasmids: M1-M4, with two clones each. (eurekalert.org)
  • This enhanced conjugation was further replicated with a different bacterial species- Sinorhizobium meliloti, as the pSC5-carrying donor, suggesting that this mechanism can be used with different bacteria. (eurekalert.org)
  • Bacteria acquired up to 90 percent of their genetic material from distantly related bacteria species, according to new research from The University of Arizona in Tucson. (eurekalert.org)
  • The finding has important biomedical implications because such gene-swapping, or lateral gene transfer, is the way many pathogenic bacteria pick up antibiotic resistance or become more virulent. (eurekalert.org)
  • Many scientists have argued that drawing traditional family trees does not make sense for bacteria, because their genomes represent a mix of genetic material from their parental cells and from other species of bacteria. (eurekalert.org)
  • The widespread exchange of genes does not blur the line of descent because the acquired genes get lost from the genome at a later point or, if they do persist, the bacteria then transmit them to their offspring. (eurekalert.org)
  • If you couldn't classify bacteria because they have genes from all over, doctors wouldn't be able to do this. (eurekalert.org)
  • But these are the genes that make bacteria different from each other. (eurekalert.org)
  • Most commonly, genes are transmitted by bacteriophages, viruses that specifically hijack bacteria cells. (eurekalert.org)
  • They inject their newly modified genetic load into other bacteria. (eurekalert.org)
  • It should be exciting to see whether gene transfer has been so widespread in other groups of bacteria, too. (eurekalert.org)
  • We hypothesized that there must be genes in the bacteria important for invading soft tissues and surviving under the skin. (scienceblog.com)
  • These genes would be good targets for a vaccine or treatment because the bacteria missing these genes did not flourish in the infection site. (scienceblog.com)
  • This is a prime location for gene products involved in infection because many dangerous bacteria secrete toxins or proteins through the membrane to attack the host. (scienceblog.com)
  • Like group A Streptococcus, many pathogenic bacteria have completely sequenced genomes, but we don't know what most of the genes are doing. (scienceblog.com)
  • A protein secreted by bacteria to kill other microbes has been re-engineered to tweak DNA inaccessible to other gene editors, scientists report online July 8 in Nature . (sciencenews.org)
  • When results of tests across 4 bacterial species were compared, the most inductive bacterial species was effective in much lower biofilm densities than weakly or non-inductive bacteria. (int-res.com)
  • In V. cholerae , CTXφ prophage transmits toxin genes among the bacteria that express the TCP prophage receptor. (nature.com)
  • By analyzing the genes of bacteria, University of Florida researchers have moved a step closer to pinpointing how two brain disorders common in small-breed dogs occur. (ufl.edu)
  • They found no difference between the genetic makeup of the bacteria from brain tissue and that of the bacteria from other sites. (ufl.edu)
  • The researchers are continuing to analyze the effects of bacterial infection on immune system cells known as macrophages to determine how the bacteria could breach the blood-brain barrier. (ufl.edu)
  • Bacteria sense these microenvironments and adapt by up or down regulating the expression of certain genes to influence different cell processes. (the-scientist.com)
  • As a novel antibacterial agent against foodborne pathogens, endolysins are peptidoglycan hydrolases encoded by bacteriophages that lyse bacterial cells by targeting their cell wall, notably in Gram-positive bacteria due to their naturally exposed peptidoglycan layer. (usda.gov)
  • In a new study in PNAS, researchers from the Max Planck Institute for Chemical Ecology and the University of Mainz, together with an international team, showed that these beneficial bacteria are losing genetic material that is no longer needed. (mpg.de)
  • Antibiotic-resistant strains of bacteria can develop in agricultural fields and then travel freely through the environment, transferring from one bacterial species to another. (enewspf.com)
  • This "horizontal gene transfer" means that a pool of resistant soil bacteria can then transfer the genetic material for resistance in human pathogens. (enewspf.com)
  • A strain of antibiotic-resistant soil bacteria may seem innocuous to humans, but the documented fact that its resistance can be transferred into human bacterial strains reveals that the use of antibiotics in agriculture can have disastrous and deadly consequences. (enewspf.com)
  • At least 20 RPSA gene mutations have been identified in individuals with isolated congenital asplenia. (medlineplus.gov)
  • RPSA gene mutations are thought to reduce the amount of functional ribosomal protein SA. (medlineplus.gov)
  • It is unclear why RPSA gene mutations solely affect the development of the spleen. (medlineplus.gov)
  • data are preliminary and based on broth microdilution susceptibility testing and/or presence of resistance genes and mutations found in whole genome sequences of bacterial DNA. (cdc.gov)
  • To create our novel plasmids, we built derivatives of the conjugative plasmid, pTA-Mob 2.0, using designed gene deletions and cluster mutations to improve bacterial conjugation with yeasts ," explained Dr. Bogumil J. Karas, Assistant Professor at University of Western Ontario and corresponding author of the study that was published in Volume 2022 of BioDesign Research on 1 September 2022 . (eurekalert.org)
  • The mutations that contributed to this increased efficiency were found to be in the promoter region of the conjugative gene traJ . (eurekalert.org)
  • In CRISPR, when that cutting is done, scientists can also insert a new bit of code or delete code, to, for example, fix disease-causing genetic mutations in the code before patching it up. (lifeboat.com)
  • Gene therapy has been utilized successfully to repair or inactivate mutations in animal models of monogenic human diseases 19 as well as human in vitro cells 12 . (nature.com)
  • Average child has 60 genetic mutations? (uncommondescent.com)
  • Although most of our variety comes from reshuffling of genes from our parents, new mutations are the ultimate source from which new variation is drawn. (uncommondescent.com)
  • These frameshift mutations in probably inactivated genes are indicators of an incipient genome erosion in Streptomyces philanthi . (mpg.de)
  • The RPSA gene provides instructions for making a protein called ribosomal protein SA, which is one of approximately 80 different ribosomal proteins. (medlineplus.gov)
  • Ribosomes process the cell's genetic instructions to create proteins. (medlineplus.gov)
  • Based on patterns in their DNA sequences, these genes likely encode proteins in the bacterial membrane. (scienceblog.com)
  • Using genetic engineering, scientists could make viral proteins (antigens) in the lab in bacterial or other cultures. (davidicke.com)
  • DNA wraps around proteins called histones such that some genes can be accessed easily by cell proteins that "read" the gene, increasing gene expression, while others are less accessible, decreasing gene expression. (cdc.gov)
  • It reduces the time lags that develop as a consequence of using proteins to activate or repress genes. (science20.com)
  • Once thought to be just a messenger that allows genetic information encoded in DNA to direct the formation of proteins, RNA (ribonucleic acid) is now known to be a highly versatile molecule that has multiple roles in cells. (cshlpress.com)
  • But FDA's findings are potentially trivial besides another recent discovery about gene-editing: that foreign DNA from surprising sources can routinely find its way into the genome of edited animals. (greenmedinfo.com)
  • During such an event, genes from the bacterial genome can be incorporated into the newly made phages. (eurekalert.org)
  • Transposons, also known as jumping genes, are short sequences of DNA that physically move within a genome, mutating genes by jumping into them. (scienceblog.com)
  • If the mutation causes an interesting effect, scientists can identify the mutated gene by locating the transposon, sequencing the DNA surrounding the transposon and mapping its location in the genome. (scienceblog.com)
  • The results of the genome test proved remarkably accurate: in 89 percent of the cases a viral signature showed itself to be distinct from a bacterial one, according to Zaas' Wednesday report in the Science Translational Medicine journal. (rt.com)
  • Using this new technique, we can cut a strawberry's genome at a desired location so that existing genes can be removed or added. (ufl.edu)
  • Lentiviral (LV) vectors of the Retroviridae family show interesting properties for monogenic gene therapy, since they integrate into the host genome and allow long-lasting gene expression 22 . (nature.com)
  • This process of inducing virulence in an otherwise harmless bacterium through prophage infection and integration of the prophage genome into the bacterial host genome is called lysogenic conversion 8 . (nature.com)
  • We wondered whether the long-term association with the host has resulted in changes in the symbiont's genome or shaped gene regulation and metabolic interactions between the beewolf and its bacterial partners," explains Mario Sandoval-Calderón, one of the first authors of the study, the motivation for this study. (mpg.de)
  • Using state-of-the-art gene sequencing techniques, the researchers were able to read out the complete genome of the symbiont. (mpg.de)
  • In participating UK research institutions, investigators can publish open access in Genome Research, Genes & Development, RNA, and Learning & Memory without article publication charges and all staff can read the entire renowned Cold Spring Harbor journal collection. (cshlpress.com)
  • Diagram describing the respective places of culture-, polymerase chain reaction-, serology- and histology-based approaches for the diagnosis of acute bacterial infections, according to the natural course of the disease. (cdc.gov)
  • Without this organ, affected individuals are highly susceptible to bacterial infections, which can be life-threatening. (medlineplus.gov)
  • One of the most common chronic bacterial oral infections, periodontitis, affects the supporting structures of the teeth. (medscape.com)
  • In a new study, McIver's laboratory and researchers at the University of Maryland School of Medicine identified two genes important for invasive group A Streptococcus infections in mice. (scienceblog.com)
  • The genes, subcutaneous fitness genes A (scfA) and B (scfB), may prove to be promising clinical targets in the fight against these infections, as there are no vaccines against group A Streptococcus or effective treatments for invasive infections. (scienceblog.com)
  • We're excited to have a method to interrogate all that unknown genetic material to better understand human infections. (scienceblog.com)
  • One very pressing problem is diagnosing and saving infants with serious bacterial infections in time. (rt.com)
  • Many bacterial infections are becoming resistant to most commonly prescribed antibiotics, resulting in longer-lasting infections, higher medical expenses, and the need for more expensive or hazardous medications. (enewspf.com)
  • Considering the coincidence between production of urease and possession of trh in V. parahaemolyticus , it was concluded that the presence or absence of the ure gene is completely coincident with that of the trh gene in V. parahaemolyticus strains. (microbiologyresearch.org)
  • The results showed that, in all the strains examined, ure and trh were detected on the same Not I fragment, showing that the two genes localise within a relatively small portion of the chromosome DNA. (microbiologyresearch.org)
  • These results suggest that the ure and trh genes are genetically linked in V. parahaemolyticus strains. (microbiologyresearch.org)
  • V. cholerae strains have incomplete virulence cassettes particularly due to the absence of genes ctxA e tcpA. (usp.br)
  • Dendrograms of intraspecific genetic similarity showed the genetic diversity among the isolated species and bacterial strains. (usp.br)
  • In Vibrio cholerae , infection by a bacterial virus (bacteriophage) results in the conversion of non-pathogenic strains to pathogenic strains and this can lead to cholera pandemics. (nature.com)
  • Slight differences in the genetic sequence of H. pylori can sometimes give certain strains advantages over others that allow it to grow better,' says lead author of the study Ryo Kinoshita-Daitoku. (news-medical.net)
  • We were interested in the genetic and molecular reasons behind why particular strains are more pathogenic and can live in the stomach for decades, leading to cancer development. (news-medical.net)
  • 1978. Appendix II: The bacterial mutation test. (cdc.gov)
  • DMDMH gave mainly negative results with in vitro bacterial mutation assays though one of the four available assays was positive. (europa.eu)
  • It gave positive results with in vitro cytogenetics, in vitro mammalian gene mutation and in vitro UDS assays. (europa.eu)
  • DMH gave negative results in all the in vitro studies performed (bacterial mutation, cytogenetics, mammalian gene mutation and UDS). (europa.eu)
  • Cystic fibrosis (CF) is an autosomal recessive condition caused by the mutation of the cystic fibrosis trans-membrane regulator gene (CFTR) on chromosome 7. (who.int)
  • Identification of emerging bacterial pathogens generally results from a chain of events involving microscopy, serology, molecular tools, and culture. (cdc.gov)
  • Plasmid delivery through conjugation between bacterial species has proven effective in creating novel antimicrobial agents, targeting specific genes to eliminate or suppress pathogens. (eurekalert.org)
  • Shigellosis is an acute enteric infection that is an important cause of domestically acquired and travel-associated bacterial diarrhea in the United States. (cdc.gov)
  • The researchers identified 273 scf genes as potentially involved in establishing infection under the skin, but two genes stood out: scfA and scfB. (scienceblog.com)
  • Here is the solution the Duke researchers came up with: photographing gene activity at the onset of infection. (rt.com)
  • But a viral infection is fought with a different set of genes than a bacterial one, for instance. (rt.com)
  • This checks for bacterial infection in the bloodstream that can affect the liver. (stanfordchildrens.org)
  • How can a live attenuated bacterial vaccine protect against viral infection? (cdc.gov)
  • An extremely common pathogenic bacterial infection is Helicobacter pylori ( H. pylori ) in the stomach, where it can lead to chronic inflammation (gastritis), ulcers, and even cancer. (news-medical.net)
  • For most commercial applications gene-editing's appeal is simplicity and precision: it alters genomes at precise sites and without inserting foreign DNA. (greenmedinfo.com)
  • Type I toxin-antitoxin (TA) systems are widespread genetic modules in bacterial genomes. (mdpi.com)
  • We demonstrate that bacteriophage genomes encoding toxin genes with homology to those found in pathogenic V. cholerae are integrated in V. coralliilyticus genomes. (nature.com)
  • The effect of Mg(2+) on regulation of global gene expression was evaluated using genomic microarrays in an M-type 3 strain of GAS and in an isogenic csrS mutant. (lu.se)
  • Trained immunity is mediated through epigenetics , the modification of gene expression without changing the genetic code. (cdc.gov)
  • Modifying these histones changes whether a gene is exposed or unexposed and therefore alters gene expression. (cdc.gov)
  • These observations suggest genetic variants can decrease mRNA expression levels by increasing usage of intronic PAS. (elifesciences.org)
  • Thus, our work demonstrates that APA links genetic variation to variation in gene expression, protein expression, and disease risk, and reveals uncharted modes of genetic regulation. (elifesciences.org)
  • NCBI Gene Expression Omnibus, GSE138197. (elifesciences.org)
  • It can function as an enzyme, scaffold various subcellular structures, and regulate gene expression through a variety of mechanisms, as well as act as a key component of the protein synthesis and splicing machinery. (cshlpress.com)
  • Culture has irreplaceable advantages for studying emerging bacterial diseases, as it allows antigenic studies, antibiotic susceptibility testing, experimental models, and genetic studies to be carried out, and remains the ultimate goal of pathogen identification. (cdc.gov)
  • Moreover, culture provided the basis of other supplemental tools to elucidate the causes of microbial disease and to study the clinical and biological features of emerging bacterial diseases. (cdc.gov)
  • To answer these questions, we examined the key steps that led to identification of most bacterial diseases that have been discovered during the last 20 years. (cdc.gov)
  • When the gene-editing technology CRISPR first made a splash back in 2012, it foretold a future in which curing diseases might simply involve snipping out problematic bits of genetic code. (lifeboat.com)
  • Their organization as well as their protein sequences showed high similarity to those of other type II PKS genes. (nih.gov)
  • The polymerase chain reaction with mixed oligonucleotide primers targeted for conserved sequences of reported ure genes from other species was used to prepare a DNA probe to detect the V. parahaemolyticus ure gene. (microbiologyresearch.org)
  • Phylogenetic relationships among 4 marine-biofilm bacterial species identified by 16S rDNA sequences were not predictive of their inductive capacity. (int-res.com)
  • ③ The antitumor response of the activated CD8+ T cells is further enhanced by bacterial flagellin (a protein subunit of the bacterial flagellum) via TLR5 activation. (wikipedia.org)
  • The continuous region included the genes for the minimal PKS, consisting of ketosynthase I (aknB), ketosynthase II (aknC), and acyl carrier protein (aknD). (nih.gov)
  • This also leads to differing RNA and protein formations, otherwise known as a genetic fingerprint. (rt.com)
  • These individuals] lack a gene or have a protein that is no longer functional. (the-scientist.com)
  • One of the pathogenic factors was the bacterial protein CagA, which is known as an oncoprotein because it can promote cancer development. (news-medical.net)
  • Plasmid stabilization/stability protein-encoding genes were observed in some plasmids but were not established for participating in plasmid segregation. (frontiersin.org)
  • Investments in next generation sequencing (NGS) methods over the previous 5 years now allow scientists to identify the genetic variations among many different influenza virus particles in a single sample. (cdc.gov)
  • But until now scientists did not know which of a bacterium's genes came from lateral gene transfer and which had been inherited from its parent. (eurekalert.org)
  • Scientists report a new gene-editing tool that can target DNA in mitochondria (red). (sciencenews.org)
  • Now, scientists at UCLA have come up with a way to edit multiple genes at once. (lifeboat.com)
  • When scientists use CRISPR for genetic engineering, they are really using a system made up of several parts. (lifeboat.com)
  • An intriguing question for many scientists is what makes bacterial cooperation persist when cheaters exist in several natural and disease settings. (the-scientist.com)
  • When this RNA was completely absent, the amounts of several bacterial pathogenic factors significantly increased and the strain showed stronger colonization within the rodent stomach. (news-medical.net)
  • These novel findings provide crucial information regarding the molecular and genetic landscape of highly pathogenic H. pylori and may assist in the development of innovative therapeutics for the treatment of H. pylori related illnesses, including gastric cancer. (news-medical.net)
  • The identification of genes involved in replication, segregation, toxin-antitoxin systems and conjugation, would aid the design of drugs to prevent the survival or transmission of plasmids carrying pathogenic properties. (frontiersin.org)
  • An analysis of the results indicated that there was little overlap between the three groups, "indicating distinct species and antibiotic resistance gene composition between all groups," the authors wrote. (genomeweb.com)
  • Looking at antibiotic resistance genes, they identified 60 that best classified the samples, although there was no difference in the abundance of drug-resistance genes between groups. (genomeweb.com)
  • The inpatient and outpatient cohorts had a somewhat surprisingly similar proportion of antibiotic-resistance genes. (genomeweb.com)
  • In particular, the authors were "surprised to find a relatively high prevalence of clinically important bacterial species and antibiotic-resistance genes" in outpatient samples, despite not being on antibiotics at the time. (genomeweb.com)
  • The researchers did identify differences between the inpatient and outpatient groups when looking at specific types of antibiotic-resistance genes. (genomeweb.com)
  • Each of Recombinetics' calves possessed two antibiotic resistance genes, along with other segments of superfluous bacterial DNA. (greenmedinfo.com)
  • Additionally, genes conferring virulence and antibiotic resistance were identified amongst the plasmids. (frontiersin.org)
  • The impact is enhanced if coupled with the presence of functional genes for antibiotic resistance. (frontiersin.org)
  • 1. Bacterial resistance to beta-lactam antibiotics has risen dramatically in Escherichia coli from food animals. (who.int)
  • For instance, two inpatient samples, or 24 percent, had the vancomycin regulatory resistance gene, while none had that gene in the outpatient group. (genomeweb.com)
  • Meanwhile, more than half of the outpatient cohort had an AmpC resistance gene, while 24 percent of inpatient samples had that gene. (genomeweb.com)
  • When comparing the sequencing method to culture, the researchers found that the culture missed several drug-resistance genes and was "cumbersome and required additional testing given the growth of isolates not intended to be selected on all types of screening media. (genomeweb.com)
  • The researchers noted that their next step would be to develop prediction models in order to better stratify patients according to their risk of developing a multi-drug resistance bacterial based on their metagenomic sequencing profile. (genomeweb.com)
  • We anticipate that, over the next decade, CRISPR and other gene editing techniques will be used to rapidly develop elite strawberry varieties with improved disease resistance, fruit quality, and other valuable attributes. (ufl.edu)
  • For example, instead of breeding for many years to move a disease resistance gene from a wild strawberry into a modern strawberry, gene editing allows a direct introduction of the genetic information. (ufl.edu)
  • The UF/IFAS strawberry breeding program has identified several important gene regions controlling disease resistance traits that are directly relevant to Florida growers. (ufl.edu)
  • The percent of larvae that metamorphosed correlated positively with bacterial density in either natural biofilms or biofilms composed of a single bacterial species. (int-res.com)
  • 1 These public goods can take many forms in a bacterial community: exopolysaccharides to build biofilms, enzymes that degrade antibiotics, or scavenging molecules to cope with nutrient scarcity in the environment. (the-scientist.com)
  • Aim Campylobacter is the leading bacterial pathogen that causes foodborne illnesses worldwide. (usda.gov)
  • Depending on the genes it carries, it could act as a fitness factor to the host, or serve as a virulence factor by transforming the host into a pathogen. (frontiersin.org)
  • pTA-Mob 2.0 is composed of genetic elements required for plasmid maintenance and transfer, making it ideal for this study. (eurekalert.org)
  • ① Bacterial toxins from S. Typhimurium, Listeria, and Clostridium can kill tumor cells directly by inducing apoptosis or autophagy. (wikipedia.org)
  • These tools are not only antigenic and serologic assays but also in vitro and in vivo disease models for pathophysiologic studies and antimicrobial susceptibility testing, plus extensive genetic sequencing. (cdc.gov)
  • These include blood tests and other forms of testing to determine genetic susceptibility to uveitis. (bumrungrad.com)
  • When a virus invades, the bacterial immune system sends an enzyme like Cas9 to the virus and chops it up. (lifeboat.com)
  • 4, 5 Another example of an exploitable compound is a bacterial enzyme used to degrade antibiotics. (the-scientist.com)
  • While they identified over 2,000 distinct bacterial species, further analysis revealed that 79 species tended to classify samples into their respective cohorts. (genomeweb.com)
  • Understanding the presence of plasmid vectors requires an appreciation of the basics of gene-editing, which, confusingly, are considerably distinct from what the word 'editing' means in ordinary English. (greenmedinfo.com)
  • Those energy-producing organelles are inherited from a mother and have their own DNA, distinct from the genetic information - from both parents - that's stored in a cell's nucleus. (sciencenews.org)
  • The researchers then computed family trees, taking into account the acquired genes, and matched the trees to an established reference tree. (eurekalert.org)
  • Armed with this knowledge, researchers tweak bacterial genetic material to better understand cheating. (the-scientist.com)
  • Researchers have already designed a 'tool box' of small genetic components that act as intracellular switches, logic gates, counters and oscillators but wiring those components together to form larger circuits that can function as 'genetic programs' has been difficult, because of the small number of available wires. (science20.com)
  • The new coupling method is capable of reducing the signaling time delay between individual genetic circuits by more than an order of magnitude," said Jeff Hasty, a professor of biology and bioengineering at UC San Diego who headed the team of researchers and co-directs the university's BioCircuits Institute. (science20.com)
  • Plasmids are small genetic structures that are independent from the chromosomes and can replicate on their own. (eurekalert.org)
  • Examples will be chosen from prokaryotic and eukaryotic organisms and topics include: principles of heredity and variation and their application to evolution and development, phsicochemical nature of the gene, problems of recombination and gene action, selection. (sabanciuniv.edu)
  • To begin addressing this gap, we used 3' Seq to study the impact of genetic variation on alternative polyadenylation (APA) in the nuclear and total mRNA fractions of 52 HapMap Yoruba human lymphoblastoid cell lines. (elifesciences.org)
  • The presence of these genetic signatures indicates virulence in V. coralliilyticus is driven by prophages and other horizontally acquired elements. (nature.com)
  • The objective of this study was to determine if serum soluble CD14 (sCD14) levels are associated with lung function among agricultur al workers and if this association is modified by genetic variants in CD14. (cdc.gov)
  • By using CRISPR technology, these genes or gene variants can be moved into desirable genetic backgrounds that can be further moved via conventional crossing in later generations. (ufl.edu)
  • Further genetic analyses provided hints that the metabolism of the bacterial symbionts is mainly directed towards the production of antibiotic substances necessary for the protection of the beewolves' offspring. (mpg.de)
  • 2021) A bacterial small RNA regulates the adaptation of Helicobacter pylori to the host environment. (news-medical.net)
  • CRISPR gene-editing systems can easily cut many pieces of DNA at once, but actually editing all those genes is a lot more time-consuming. (lifeboat.com)
  • CRISPR is a tool taken from bacterial immune systems. (lifeboat.com)
  • This approach is known as 'CRISPR' gene editing. (ufl.edu)
  • What is CRISPR gene editing? (ufl.edu)
  • CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is one form of gene editing that can be used to precisely modify a gene of interest without otherwise compromising the favorable traits of an elite variety (Rani et al. (ufl.edu)
  • Does CRISPR gene editing = transgenic technology? (ufl.edu)
  • We published another article about CRISPR gene editing in crop improvement ( https://edis.ifas.ufl.edu/publication/HS1334 ). (ufl.edu)
  • ② Upon exposure to tumor antigens and interaction with bacterial components, DCs secrete robust amounts of the proinflammatory cytokine IL-1β, which subsequently activates CD8+ T cells. (wikipedia.org)
  • 2. Nuclear transfer is a technique used to duplicate genetic material by creating an embryo through the transfer and fusion of a diploid cell in an enucleated female oocyte.2 Cloning has a broader meaning than nuclear transfer as it also involves gene replication and natural or induced embryo splitting (see Annex 1). (who.int)
  • Replication genes were not identified in some plasmids, a situation that has led to the possibility of host interaction involvement. (frontiersin.org)
  • Transgenic technology' refers to the transfer of a genetic material from one species to another. (ufl.edu)
  • A clone is an organism that is a genetic copy of an existing one. (who.int)
  • Before a person even feels the first symptoms of an illness, sets of genes are dispatched by the organism to battle it. (rt.com)
  • The book goes on to discuss the evolution of ribosomes and the functions of RNPs, before reviewing the recent work that has revolutionized our understanding of gene regulation by non-coding RNAs, including miRNAs and siRNAs. (cshlpress.com)
  • Sputum culture grew Pseudomonas aeruginosa and blood and urine cultures revealed no bacterial growth. (who.int)
  • We have cloned and sequenced polyketide synthase (PKS) genes from the aclacinomycin producer Streptomyces galilaeus ATCC 31,615. (nih.gov)
  • To maintain effective treatments and develop new antibiotics, it's important to monitor the rates and patterns of lateral gene transfer," said team member Howard Ochman, a UA professor of biochemistry and molecular biophysics and a member of UA's BIO5 Institute. (eurekalert.org)
  • Ochman's team compared the bacterial species by analyzing their genomic sequence data. (eurekalert.org)
  • Ochman and his colleagues' work shows that bacterial lineages can still be traced by considering only the "traditional" forms of genetic inheritance. (eurekalert.org)
  • Genetic analysis revealed that a specific part of the H. pylori gene, called the T-repeat region, varied in length from strain to strain. (news-medical.net)
  • This showed that the widespread mechanism of lateral gene transfer does not interfere with the traditional approach of using family trees to infer relationships. (eurekalert.org)
  • Moreover, we present strong evidence that Mg(2+) signals through CsrS to regulate an extensive and previously undefined repertoire of GAS genes. (lu.se)
  • Based on policy discussions, it is possible that the first-generation plants containing the edited genes will not require extensive regulation, and these tools will be extremely valuable in the long-term efforts of every strawberry breeding program. (ufl.edu)