• Scientists believe that the study of genes that encode the proteins for molecular motors will help solve the mysteries of evolution. (icr.org)
  • Researchers had hoped to find that matters would be clarified by myosin proteins derived from the DNA sequences of different single-celled eukaryotes, such as flagellated protozoa (protozoa with a whip-like tail), amoeboid protozoa, and algae. (icr.org)
  • Cytosine C5 methylation is an important epigenetic control mechanism in a wide array of eukaryotic organisms and generally carried out by proteins of the C-5 DNA methyltransferase family (DNMTs). (mdpi.com)
  • More than half of all human genes are alternatively spliced, so it is expected that alternative pre- mRNA splicing will be responsible for the identification of more than 90 percent of all human proteins. (genomicglossaries.com)
  • retained genes for the last three steps of the pathway, allowing The most abundant group of heme proteins are cytochromes them to synthesize heme from their host-derived precursors (20). (medicinelakex1.com)
  • Genes vary in size, depending on the sizes of the proteins or RNA for which they code. (msdmanuals.com)
  • Microbiologists often rely on molecular biology tools such as DNA sequence based identification, example 16s rRNA gene sequence used for bacteria identification. (labroots.com)
  • The human body shelters a zoo of microbes - thousands of bacteria, viruses, fungi, and protozoa. (harvard.edu)
  • Meyerson then realized that the DNA must be from bacteria present in the human cells he was studying. (harvard.edu)
  • To test the idea further, Meyerson and his colleagues checked libraries of human DNA and discovered that some of the DNA sequences came from bacteria, viruses, and fungi present in people who contributed tissue samples to the genome project. (harvard.edu)
  • The microbes included viruses associated with hepatitis, liver cancer, and cervical cancer, a virus involved with skin tumors in AIDS patients, and a menagerie of other bacteria, fungi, and protozoa. (harvard.edu)
  • In the Human Microbiome Project, researchers plan to characterize the vast numbers of bacteria, fungi, protozoa and viruses in our body by sequencing their genes. (popsci.com)
  • Herbivores rely on digestive tract lignocellulolytic microorganisms, including bacteria, fungi and protozoa, to derive energy and carbon from plant cell wall polysaccharides. (concordia.ca)
  • Our 2.0 DNA Analysis identifies and quantifies nearly all bacteria and archaea that are important in anaerobic digestion using 16S rRNA amplicon sequencing and qPCR. (microbedetectives.com)
  • Until the 1970s, diagnostic techniques for infectious diarrhea were limited to bacteria and protozoa, and an etiologic agent could be identified in a limited proportion of cases. (cdc.gov)
  • AIM2 inflammasome plays a crucial role in the defense against viral infection as genetic material from DNA viruses that enter the cytoplasm can be recognized. (wikipedia.org)
  • However, AIM2 does not respond to all DNA viruses. (wikipedia.org)
  • In contrast, chromosomes in the MAC genome undergo extensive DNA fragmentation, elimination and amplification, followed by telomere addition ( Prescott 1994 ), resulting in many small acentric chromosomes. (pomona.edu)
  • 27nt-RNAs guide histone variant deposition via 'RNA-induced DNA replication interference' and thus transmit parental genome partitioning in Stylonychia. (uni-bielefeld.de)
  • The Human Genome Project is close to completing an inventory of all human genes. (harvard.edu)
  • He found three such fragments of DNA, and checked them against sequences mapped by the Human Genome Project. (harvard.edu)
  • Now, advances in DNA sequencing-the very same that made it possible for the Human Genome Project to decode the three billion base pairs of our own genome quickly-have provided the technology to make a comprehensive Human Microbiome Project possible. (popsci.com)
  • Its individual sections are called genes, and the set of these genes in any given organism is called the genome. (avcr.cz)
  • To simplify and paint an illustrative analogy (see Figure 1 below), a gene can be thought of as a single sentence beginning with a capital letter and ending with a full stop, whereas the genome is the book itself telling the whole story. (avcr.cz)
  • W. Mitochondria1 genome range and also the advancement of mitochondrial DNA. (realprowa.com)
  • The genotype (or genome) is a person's unique combination of genes or genetic makeup. (msdmanuals.com)
  • Gene expression profiling of Leishmania (Leishmania). (cambridge.org)
  • In several protozoans, the status of this mechanism remains elusive, such as in Leishmania , the causative agent of the disease leishmaniasis in humans and a wide array of vertebrate animals. (mdpi.com)
  • The MCA gene of Leishmania major (LmjMCA) is expressed in actively replicating amastigotes and procyclic promastigotes, but at a lower level in metacyclic promastigotes. (strath.ac.uk)
  • However, these results have been underestimated because genes for the two key enzymes of the cycle, isocitrate lyase (ICL) and malate synthase (MS), are not annotated in Leishmania genomes. (degruyter.com)
  • We have cloned and characterized the Dictyostelium discoideum repE gene, a homolog of the human xeroderma pigmentosum (XP) group E gene which encodes a UV-damaged DNA binding protein. (nih.gov)
  • Subsequent genomic sequence analysis of multiple genes including elongation factor 3, a component of fungi protein synthesis not found in protozoa, further supported this notion. (medscape.com)
  • Interferon-inducible protein AIM2 also known as absent in melanoma 2 or simply AIM2 is a protein that in humans is encoded by the AIM2 gene. (wikipedia.org)
  • The PYD domain mediates homotypic protein-protein interaction, while the HIN domain binds to DNA with its two tandem oligonucleotide/oligosaccharide binding (OB) folds. (wikipedia.org)
  • Reprinted from Cell 81, Collins, Kathleen, et al, "Purification of Tetrahymena Telomerase and Cloning of Genes Encoding the Two Protein Components of the Enzyme", pg. (jhu.edu)
  • The delta-endotoxins are encoded by cry (crystal protein) genes. (justia.com)
  • Each gene contains within it the recipe for making one protein, composed of different combinations of twenty basic amino acids in a process called protein synthesis. (avcr.cz)
  • Because alternative RNA splicing allows different types of mRNA molecules to be created from a single gene, it generates the diversity of protein function and structure that is essential to complex organisms. (genomicglossaries.com)
  • Highly specific and effective gene silencing of any disease can be achieved by an accurate knowledge of the target mRNA sequence and rational design of its complementary antisense agents for the downregulation of its protein message. (genomicglossaries.com)
  • This origin is activated by the R6K specific initiator protein π, encoded by the pir gene [1]. (invivogen.com)
  • 2010) Cellulosilyticum ruminicola, a newly described rumen bacterium that possesses redundant fibrolytic-protein-encoding genes and degrades lignocellulose with multiple carbohydrate- borne fibrolytic enzymes. (concordia.ca)
  • They display considerable versatility in binding modes, even between members of the same class (e.g. some bind DNA, others protein), suggesting that Znf motifs are stable scaffolds that have evolved specialised functions. (embl.de)
  • on the basis of nuclear protein-coding genes. (obihiro.ac.jp)
  • Genes are segments of deoxyribonucleic acid (DNA) that contain the code for a specific protein that functions in one or more types of cells in the body or the code for functional ribonucleic acid (RNA) molecules. (msdmanuals.com)
  • Protein synthesis is controlled by genes, which are contained on chromosomes. (msdmanuals.com)
  • DNA contains the code, or blueprint, used to synthesize a protein or a ribonucleic acid (RNA) molecule. (msdmanuals.com)
  • A gene is a segment of DNA that provides the code to construct a protein or RNA molecule. (msdmanuals.com)
  • The eukaryotic microbes include the protists (protozoa), the fungi and at least the unicellular algae. (libretexts.org)
  • When Professor Dag Klaveness of MERG wants to catch the protozoan, he sticks a pipe down into the lakebed, removes a column of sludge and pours a bile green algae mixture over it. (sciencenorway.no)
  • The algae are such tempting morsels for the small protozoa that they swim up. (sciencenorway.no)
  • We also identify and quantify eukaryotic organisms such as Protists (Protozoa, Amoeba, Algae) and Fungi for anaerobic digestion systems requiring diagnostics on higher life forms. (microbedetectives.com)
  • DNA in the MIC remains organized in the form typical of most eukaryotes, with pairs of large chromosomes. (pomona.edu)
  • In ciliates belonging to the class Spirotrichea the level of DNA processing in the formation of a new MAC is extraordinary: the original zygotic chromosomes are fragmented at tens of thousands of positions, 95% of the DNA complexity is lost, and the resulting chromosomes - sometimes referred to as "nanochromosomes" - are amplified to thousands of copies each ( Prescott 1994 ). (pomona.edu)
  • Brand new HOPl gene encodes good meiosisspecific part of fungus chromosomes. (realprowa.com)
  • Chromosomes are structures within cells that contain a person's genes. (msdmanuals.com)
  • Genes are contained in chromosomes, which are in the cell nucleus. (msdmanuals.com)
  • DNA (deoxyribonucleic acid) is the cell's genetic material, contained in chromosomes within the cell nucleus and mitochondria. (msdmanuals.com)
  • This protozoan parasite evades the host immune system by antigenic variation, a periodic switching of its variant surface glycoprotein (VSG) coat. (nih.gov)
  • Studies on the protozoan parasite, Entamoeba histolytica suggest that in its proliferative phase, this organism may accumulate polyploid cells. (ias.ac.in)
  • shown to possess antimicrobial activity and are fed to cattle suffering from East Coast Fever (caused by the protozoan parasite 439.1216 [M+Na]+ (calcd. (careersfromscience.org)
  • Chagas disease, also known as American trypanosomiasis, is caused by infection with the protozoan parasite Trypanosoma cruzi . (medscape.com)
  • The repE gene is not expressed by mitotically dividing cells, and repE mRNA is first detected during the aggregation phase of development when the cells have ceased dividing and replicating genomic DNA. (nih.gov)
  • Instead, they noted that 'we provide an integrative and robust classification, useful for future genomic and functional studies on this crucial eukaryotic gene family. (icr.org)
  • However in recent years with the development of epigenesis, genomic imprinting and the horizontal transferences of the genes, Lamarck's ideas have resurfaced. (intechopen.com)
  • The Giardia lamblia vsp gene repertoire: characteristics, genomic organization, and evolution. (mbl.edu)
  • In the 1980s, biochemical analysis of the nucleic acid composition of Pneumocystis rRNA and mitochondrial DNA identified the organism as a unicellular fungus rather than a protozoan. (medscape.com)
  • Phylogenetic affiliations of mesopelagic acantharia and acantharian-like environmental 18S rRNA genes off the southern California coast. (mbl.edu)
  • The DNA extracted from each sample was subjected to polymerase chain reaction (PCR) targeting the genes 23S rRNA for the Anaplasmataceae family, 16S rRNA for Anaplasma spp. (bvsalud.org)
  • and 18S rRNA for Piroplasmid protozoans. (bvsalud.org)
  • High- fidelity mRNA amplification for gene profiling. (genomicglossaries.com)
  • Transcription from the targeted endogenous genes is normally normal, although mRNA levels dramatically decrease. (thetechnoant.info)
  • Metacaspases (MCAs) are distant orthologues of caspases and have been proposed to play a role in programmed cell death in yeast and plants, but little is known about their function in parasitic protozoa. (strath.ac.uk)
  • This parasitic protozoan does not directly attack humans, but it belongs to the Trypanosomatida group - protozoans closely related to Trypanosoma brucei , which causes the deadly disease of sleeping sickness in humans and cattle. (avcr.cz)
  • Gene Unscrambler: A program to unscramble ciliate genes. (pomona.edu)
  • A further difficulty in the study of ciliate gene rearrangements is the difficulty to annotate and retrive these genes from public databases, like GenBank. (pomona.edu)
  • High-throughput DNA sequencing of the moose rumen from different geographical locations reveals a core ruminal methanogenic archaeal diversity and a differential ciliate protozoal diversity. (sueishaqlab.org)
  • In the ciliate by microinjection at high duplicate amount (a threshold of 20C30 haploid equivalents for totally silenced phenotypes) of plasmids filled with just the coding series of the gene in to the somatic nucleus, that leads to a dramatic decrease in appearance of most endogenous homologs (39). (thetechnoant.info)
  • Meiosis during the protists, particular architectural and you will psychological aspects of meiosis within the alga, fungus, and you will protozoa.Bucferiof. (realprowa.com)
  • Direct visualisation of individual gene organisation in Trypanosoma brucei by high-resolution in situ hybridisation. (ox.ac.uk)
  • We achieved the direct visualisation of gene organisation in Trypanosoma brucei using fluorescent in situ hybridisation on extended nuclear DNA fibres. (ox.ac.uk)
  • This study provides a snapshot of eukaryotic gene expression in the muskoxen rumen, and identifies a number of candidate genes coding for potentially valuable lignocellulolytic enzymes. (concordia.ca)
  • It has also been shown that although this organism contains sequence homologs of genes which are known to control the cell cycle of most eukaryotes, these genes may be structurally altered and their equivalent function yet to be demonstrated in amoeba. (ias.ac.in)
  • Marine bacteriophages play key roles in the community structure of microorganisms, biogeochemical cycles, and the mediation of genetic diversity through horizontal gene transfer. (biomedcentral.com)
  • INTRODUCTION In microorganisms which range from protozoa to vertebrates, launch of international DNA or RNA can promote unforeseen deregulation of regular gene appearance on the post-transcriptional level (for latest reviews find 1C6). (thetechnoant.info)
  • A great conditional allele of your Succharomyces cerevisiue https://datingranking.net/tr/kasidie-inceleme/ HOPl gene is actually suppressed by overexpression away from several almost every other meiosis-certain genetics: RED1 and you will REC104. (realprowa.com)
  • however, in Oxytricha trifallax (also called Sterkiella histriomuscorum ), three of the six genes for which MIC and MAC sequences are available are scrambled. (pomona.edu)
  • After both forms of a gene are sequenced, the MDSs have to be aligned with the MAC sequences and IESs and pointer sequences must be determined based on this alignment. (pomona.edu)
  • The program automatically aligns the macronuclear and micronuclear genes and gives the coordinates of MDSs and pointer sequences. (pomona.edu)
  • One analysis of 7,000 supposedly human sequences found 44 genes from nonhumans. (harvard.edu)
  • RNA molecules which hybridize to complementary sequences in either RNA or DNA altering the function of the latter. (genomicglossaries.com)
  • AIM2 is a cytoplasmic sensor found in hematopoietic cells that recognizes the presence of double-stranded DNA (dsDNA) of microbial or host cellular origin. (wikipedia.org)
  • Karius has launched a quantitative version of its next-generation sequencing-based test that identifies microbial cell-free DNA in blood. (genomeweb.com)
  • New gene-based technologies can now be employed to examine microbial diversity through the use of small sub-unit ribosomal DNA analysis (e.g. 16S rDNA) and to understand the function of complex microbial ecosystems in the rumen through metagenomic analysis. (nhbs.com)
  • This review article explores recent microarray research studies from select protozoan and bacterial pathogens to illustrate how researchers utilize microarray technology to examine aspects of microbial infection. (innspub.net)
  • Detailed knowledge of the genes involved in the microbial infection process will lead to the discovery of disease biomarkers and potent therapeutic solutions. (innspub.net)
  • With Microbe Detectives' Anaerobic Digestion DNA Analysis, one can attain an intimate understanding of their system's microbial community, develop best practices and optimize performance. (microbedetectives.com)
  • DNA analysis) have opened a new window to the microbial world of water. (microbedetectives.com)
  • Biologists all over the world have been eagerly awaiting the results of the genetic analysis of one of the world's smallest known species, called the protozoan, from a little lake 30 kilometer south of Oslo in Norway. (sciencenorway.no)
  • When researchers from the University of Oslo compared its genes with all other known species in the world, they saw that the protozoan did not fit on any of the main branches of the tree of life. (sciencenorway.no)
  • The family tree of the protozoan from Ås starts at the root of the eukaryote species. (sciencenorway.no)
  • To calculate how much our species has changed since primordial times, we have to compare its genes with its nearest relatives, amoebae and excavates,' says Shalchian-Tabrizi. (sciencenorway.no)
  • DNA microarray detection of 18 important human blood protozoan species. (innspub.net)
  • However, the DNA sequence must be at least 80 base pairs in length. (wikipedia.org)
  • Telomerase is a ribonucleoprotein DNA polymerase that catalyzes the de novo synthesis of telomeric simple sequence repeats. (jhu.edu)
  • The latter sequence contains the telomere repeat d(T4G4) from the protozoan Oxytricha no V a . (lu.se)
  • The repE gene maps to chromosome 4 and it is the first gene identified in Dictyostelium that is homologous to those involved in nucleotide excision repair and their related XP diseases in humans. (nih.gov)
  • VSG switching is thought to occur predominantly through gene conversion, a form of homologous recombination initiated by a DNA lesion that is used by other pathogens (for example, Candida albicans, Borrelia sp. (nih.gov)
  • Homology-dependent gene silencing is definitely attained in by introduction of gene coding locations in to the somatic nucleus at high duplicate number, leading to reduced expression of most homologous genes. (thetechnoant.info)
  • The parts of a gene separated by IESs are called macronuclear destined segments ( MDSs ). (pomona.edu)
  • http://oxytricha.princeton.edu/dimorphism/database.htm ), which contains all the genes in Spirotrichs for which both versions, micronuclear and macronuclear, have been sequenced, and allows the user to search for genes of interest using several parameters. (pomona.edu)
  • 2002 ) Coding properties of macronuclear DNA molecules in Sterkiella nova (Oxytricha nova). (academictree.org)
  • Experts have discovered that this newly described protozoan exhibits a completely unpredictable and distinct deviation from the genetic code that is otherwise identical in the vast majority of organisms, including humans. (avcr.cz)
  • A biological process that is crucial for gene expression in most animal life, including humans. (genomicglossaries.com)
  • Humans have about 20,000 to 23,000 genes. (msdmanuals.com)
  • Bacterial DNA is released into cytoplasm during infection of a host cell, where it is recognized by AIM2 and other cytoplasmic DNA sensors. (wikipedia.org)
  • Here we demonstrate that the introduction of a DNA double-stranded break (DSB) adjacent to the approximately 70-base-pair (bp) repeats upstream of the transcribed VSG gene increases switching in vitro approximately 250-fold, producing switched clones with a frequency and features similar to those generated early in an infection. (nih.gov)
  • An understanding of host-pathogen interactions related to the expression of essential genes during and after infection can lead to valuable information for biologists and clinicians. (innspub.net)
  • Vitamin E scaffolds of pH-responsive lipid nanoparticles as DNA vaccines in cancer and protozoan infection. (invivogen.com)
  • Infection with the protozoan Toxo- these patients [11,12]. (who.int)
  • DNA, which are released from the contents monia AND neutrophil extracellular traps, of neutrophils as a defense mechanism to respiratory tract infection AND neutrophil trap and destroy microorganisms1. (bvsalud.org)
  • We were also able to detect spontaneous DSBs within the 70-bp repeats upstream of the actively transcribed VSG gene, indicating that a DSB is a natural intermediate of VSG gene conversion and that VSG switching is the result of the resolution of this DSB by break-induced replication. (nih.gov)
  • Typically, the elements required for replication and selection of the plasmid in E. coli and gene expression in mammalian cells are rich in CpG. (invivogen.com)
  • Due to the presence of the R6K gamma origin of replication, pCpGfree plasmids can only be amplified in an E. coli mutant strain expressing a pir mutant gene. (invivogen.com)
  • LmjMCA has a punctate distribution throughout the cell in interphase cells, but becomes concentrated in the kinetoplast (mitochondrial DNA) at the time of the organelle's segregation. (strath.ac.uk)
  • Amplification of cry genes has been achieved in Bacillus subtilis. (justia.com)
  • This signaling contributes to the defense against bacterial and viral DNA. (wikipedia.org)
  • Ciliated protozoans (Phylum Ciliophora) are characterized by the presence of cilia - used for locomotion, and the presence of two types of nuclei: a somatic nucleus - macronucleus (MAC) - which provides templates for the transcription of all genes required for vegetative growth, and a genetic nucleus - micronucleus (MIC) - used for the exchange of meiotic products during sexual reproduction. (pomona.edu)
  • Some micronuclear genes have their MDSs present in a permuted order, compared to the functional gene in the macronucleus. (pomona.edu)
  • 2002 ) Topological organization of DNA molecules in the macronucleus of hypotrichous ciliated protozoa. (academictree.org)
  • 1 Instead of finding a pattern of evolving myosin 'motor' genes (simple to complex) as life seemingly became more advanced, they found that the highest numbers of different types of myosin genes were found in single-celled eukaryotes. (icr.org)
  • Researchers from the Institute of Parasitology of the Biology Centre of the CAS and the Institute of Microbiology of the CAS have discovered a molecular mechanism that has evolved in this protozoan to allow the reader (ribosome) to navigate through its genetic sentences as if there were no extra full stops. (avcr.cz)
  • The absence of MCAs from mammals makes the enzyme a potential drug target against protozoan parasites. (strath.ac.uk)
  • The first step in the formation of AIM2 inflammasome is DNA binding. (wikipedia.org)
  • STING-associated vasculopathy with onset in infancy (SAVI)] as well as diseases associated with gain of function mutations in inflammasome genes (e.g. (umassmed.edu)
  • Homologs of several vB_OliS_GJ44 genes have mostly been found in marine metagenomes, suggesting the prevalence of this phage genus in the oceans. (biomedcentral.com)
  • The authors stated, 'The number of myosin genes varies markedly between lineages [types of eukaryotes],' and 'holozoan genomes, as well as some amoebozoans and heterokonts, have the highest numbers of myosins of all eukaryotes. (icr.org)
  • Thus, alternation of DNA duplication (S-phase) and chromosome segregation during the M-phase are hallmarks of most well studied eukaryotes. (ias.ac.in)
  • Ehrenfeucht A, Prescott DM, Rozenberg G. ( 2007 ) A model for the origin of internal eliminated segments (IESs) and gene rearrangement in stichotrichous ciliates. (academictree.org)
  • Prescott DM, Ehrenfeucht A, Rozenberg G. ( 2003 ) Template-guided recombination for IES elimination and unscrambling of genes in stichotrichous ciliates. (academictree.org)
  • DNA microarray-based detection of nosocomial pathogenic Pseudomonas aeruginosa and Acinetobacter baumannii . (innspub.net)
  • In: Gene Variations from inside the Fungus (J. W. Bennett, L. L. Lasure, eds. (realprowa.com)
  • HOP1: a beneficial fungus meiotic pairing gene. (realprowa.com)
  • Constructs with and without promoters induce gene silencing. (thetechnoant.info)
  • In some full cases, dsRNA could possibly be made by the transgenes, by transcription from cryptic promoters or through inverted DNA repeats. (thetechnoant.info)
  • Genetic information is stored in DNA molecules. (avcr.cz)
  • Due to the interaction of these two modified molecules, the ribosome of this protozoan knows when to end a sentence correctly (regardless of the abundance of full stops) and conversely when to replace the full stops with the two original letters (E and P), which gives the story (genetic information) back its meaning. (avcr.cz)
  • These aberrantly sized RNA molecules hybridize having a plasmid probe, suggesting that they are synthesized from your microinjected DNA (39). (thetechnoant.info)
  • The study of gene scrambling in ciliates is complicated by the difficulties in sequencing and annotating micronuclear genes. (pomona.edu)
  • 2003 ) Formal systems for gene assembly in ciliates Theoretical Computer Science . (academictree.org)
  • pCpG plasmids contain two MARs, from the 5' region of the human IFN-β gene or β-globin gene that were chosen because they are naturally CpG-free. (invivogen.com)
  • Choice models claim that the forming of aberrant RNA will not need transcription of presented DNA, but outcomes from ectopic pairing with endogenous DNA that inhibits regular transcription (33,34). (thetechnoant.info)
  • Not only is intergenic DNA lost during the conversion from MIC to MAC, but genes in the MIC are interrupted by non-coding A-T rich segments called internal eliminated segments ( IESs ) that must be removed. (pomona.edu)
  • Pharmaceutical biology antisense, antisense DNA, antisense oligonucleotides. (genomicglossaries.com)
  • 16, 17 ) for B -DNA oligonucleotides. (lu.se)
  • AIM2 is a component of the innate immune system that functions as a cytoplasmic dsDNA sensor playing a role in antiviral and antibacterial defenses, as well as in autoimmune diseases involving self DNA. (wikipedia.org)
  • it can be used as a DNA vaccine carrier for antigen presentation, and as an immune-stimulative adjuvant [1]. (invivogen.com)
  • 2015. A KALA-modified lipid nanoparticle containing CpG-free plasmid DNA as a potential DNA vaccine carrier for antigen presentation and as an immune-stimulative adjuvant. (invivogen.com)
  • Appearance of most endogenous genes writing homology using the international nucleic acidity is normally silenced or decreased, in what continues to be likened to a hereditary immune system. (thetechnoant.info)
  • Endogenous antisense RNAs function as regulators of gene expression by a variety of mechanisms. (genomicglossaries.com)
  • Synthetic antisense RNAs are used to effect the functioning of specific genes for investigative or therapeutic purposes. (genomicglossaries.com)
  • presents an opportunity to manipulate gene expression within the cells to treat various diseases, and acts as a powerful tool for studying gene function utilizing antisense agents to manage the diseases by regulating the expression of the specific factor that actually causes the particular disease. (genomicglossaries.com)
  • Nevertheless, transgenes which contain 3 non-coding locations usually do not induce gene silencing, despite antisense RNA creation. (thetechnoant.info)
  • On the biological level, we demonstrate that gene expression levels fluctuate during in vitro development of both intracellular amastigotes and promastigotes. (cambridge.org)
  • Its genetic "deviation" makes the new protozoan incredibly valuable for further biological research, as it may allow researchers to manipulate the genetic code in ways previously unimagined. (avcr.cz)
  • this is particularly a delicate task for intracellular amastigotes and for specific 'sensory' genes. (cambridge.org)
  • Gene expression profiling is increasingly used in the field of infectious diseases for characterization of host, pathogen and the nature of their interaction. (cambridge.org)
  • They think that the genes in their cells, their DNA, determines whether they will get diseases like diabetes or heart disease. (wholehealthaustin.com)
  • The gene encoding AIM2 was originally isolated from human melanoma cells. (wikipedia.org)
  • The way to be sure was to subtract out all the known human DNA from the cells he was working with. (harvard.edu)
  • Babesia microti, an intraerythrocytic protozoan and the etiological agent of human babesiosis, is transmitted by the bite of the tick, Ixodes ricinus. (edu.pl)
  • We demonstrated the repetitive nature of the tubulin gene cluster, which consists of up to 19 alpha- and beta-tubulin genes arranged in tandem repeats. (ox.ac.uk)
  • Fetal toxoplasmosis, particularly in detection of circulating DNA is the anti-T. gondii antibodies early pregnancy can cause miscarriage, only clue to its reactivation [15]. (who.int)
  • In various other cases, it's been postulated MGCD0103 distributor which the introduced DNA creates aberrant RNAs that could serve as template for an RNA-dependent RNA polymerase (RdRP) to synthesize a complementary RNA (cRNA) that may hybridize with feeling RNA to create dsRNA (9,11,14,17,31,32). (thetechnoant.info)
  • Such irregular RNAs will also be found in some instances of co-suppression in vegetation (40,41) and are postulated to play a role in initiating gene silencing. (thetechnoant.info)
  • The prevalence of B. microti was studied using the PCR method with primers complementary to the gene fragment encoding nuclear small-subunit ribosomal RNA (ss-rDNA). (edu.pl)
  • The Zeocin™ resistance gene is a small gene (Furthermore, all Dam methylation sites (GATC) have been removed to prevent prokaryotic methylation. (invivogen.com)