Fredrickson, hyperlipidemias. Medical search. FAQ

dyslipidemia
Reduce elevated total cholesterol (total-C), low-density lipoprotein cholesterol (LDL-C), apolipoprotein B (Apo B), and triglycerides (TG), and to increase high-density lipoprotein cholesterol (HDL-C) in patients with primary hyperlipidemia (Fredrickson type IIa, heterozygous familial and nonfamilial) or mixed dyslipidemia (Fredrickson type IIb). (drugs.com)
Reduce elevated total-C, LDL-C, Apo B, TG and increase HDL-C in patients with primary hyperlipidemia (heterozygous familial and nonfamilial) and mixed dyslipidemia. (nih.gov)
Adjunctive therapy to diet for the reduction of low-density lipoprotein cholesterol (LDL-C), total cholesterol (total-C), triglycerides, and apolipoprotein B (apo B), and to increase high-density lipoprotein cholesterol (HDL-C) in adults with primary hypercholesterolemia or mixed dyslipidemia (Fredrickson types IIa and IIb). (drugs.com)
The primary uses of atorvastatin is for the treatment of dyslipidemia and the prevention of cardiovascular disease: Hypercholesterolemia (heterozygous familial and nonfamilial) and mixed dyslipidemia (Fredrickson types IIa and IIb) to reduce total cholesterol, LDL-C, apo-B, triglycerides levels, and CRP as well as increase HDL levels. (wikipedia.org)

hypertriglyceridemia
Reduce elevated TG in patients with hypertriglyceridemia (Fredrickson type IV hyperlipidemia). (drugs.com)
Adjunctive therapy to diet for treatment of adult patients with severe hypertriglyceridemia (Fredrickson types IV and V hyperlipidemia). (drugs.com)
Hyperlipidemias are also classified according to which types of lipids are elevated, that is hypercholesterolemia, hypertriglyceridemia or both in combined hyperlipidemia. (wikipedia.org)
Heterozygous familial hypercholesterolemia in pediatric patients Homozygous familial hypercholesterolemia Hypertriglyceridemia (Fredrickson Type IV) Primary dysbetalipoproteinemia (Fredrickson Type III) Combined hyperlipidemia Primary prevention of heart attack, stroke, and need for revascularization procedures in patients who have risk factors such as age, smoking, high blood pressure, low HDL-C, and a family history of early heart disease, but have not yet developed clinically evident coronary heart disease. (wikipedia.org)

Classification
15 In 1967, The New England Journal of Medicine published "Fat transport in lipoproteins-an integrated approach to mechanisms and disorders," a 5-part description of the system that came to be known as the Fredrickson Classification of the Hyperlipidemias. (ahajournals.org)
Familial hyperlipidemias are classified according to the Fredrickson classification, which is based on the pattern of lipoproteins on electrophoresis or ultracentrifugation. (wikipedia.org)
Fredrickson Classification: Testing the general population under the age of 40 without symptoms is of unclear benefit. (wikipedia.org)
A pattern compatible with hyperlipoproteinemia type IIa on the Fredrickson classification is typically found: raised level of total cholesterol, markedly raised level of low-density lipoprotein (LDL), normal level of high-density lipoprotein (HDL), and normal level of triglycerides. (wikipedia.org)

dyslipidemias
WELCHOL has not been studied in Fredrickson Type I, III, IV, and V dyslipidemias. (nih.gov)
Atorvastatin calcium tablets have not been studied in Fredrickson Types I and V dyslipidemias. (nih.gov)

lipoprotein cholesterol
reduce elevated low-density lipoprotein cholesterol (LDL-C) in adults with primary hyperlipidemia as monotherapy or in combination with a hydroxymethyl-glutaryl-coenzyme A (HMG CoA) reductase inhibitor (statin) ( 1.1 ). (nih.gov)

adults with primary
WELCHOL is indicated as an adjunct to diet and exercise to reduce elevated low-density lipoproteincholesterol ( LDL - C ) in adults with primary hyperlipidemia ( Fredrickson Type IIa) as monotherapy or in combination with a hydroxymethyl-glutaryl- coenzyme A (HMG CoA) reductase inhibitor (statin). (rxlist.com)

primary
Reduce elevated TG and VLDL-C in patients with primary dysbetalipoproteinemia (Fredrickson type III hyperlipidemia). (drugs.com)
Hyperlipidemias are divided into primary and secondary subtypes. (wikipedia.org)
Primary hyperlipidemia is usually due to genetic causes (such as a mutation in a receptor protein), while secondary hyperlipidemia arises due to other underlying causes such as diabetes. (wikipedia.org)
Hyperlipidemias may basically be classified as either familial (also called primary) caused by specific genetic abnormalities, or acquired (also called secondary) when resulting from another underlying disorder that leads to alterations in plasma lipid and lipoprotein metabolism. (wikipedia.org)

elevation
Flolipid has not been studied in conditions where the major abnormality is elevation of chylomicrons (i.e., hyperlipidemia Fredrickson types I and V). (drugs.com)

type
Clinical observations of Xuezhikang for treatment of mixed type of hyperlipidemia. (etok.info)
Two follow-up studies were carried out to determine whether lower birthweight is related to the occurrence of syndrome X - Type 2 (non-insulin-dependent) diabetes mellitus, hypertension and hyperlipidaemia. (springer.com)
Type III hyperlipidemia may be associated with xanthomata of the palms, knees and elbows. (wikipedia.org)

lipids
Hyperlipidemia is abnormally elevated levels of any or all lipids or lipoproteins in the blood. (wikipedia.org)

National Heart Ins
During his 2 decades as a clinical and basic research scientist at the National Heart Institute, Don Fredrickson was part of a remarkable team that helped transform our understanding of the pathophysiology of cardiovascular disease. (ahajournals.org)

patients
While these drugs are useful for patients with hyperlipidemia, Tangier's disease patients do not benefit from these pharmaceutical interventions. (wikipedia.org)

treatment
Cong B. Observations on the therapeutic effects of Zhibituo for treatment of hyperlipidemia. (etok.info)
Xuezhikang capusule in the treatment of hyperlipidemia. (etok.info)