DiseasesChemicals and DrugsAnalytical, Diagnostic and Therapeutic Techniques and EquipmentInformation Science
Jejunoileal BypassHyperlipidemiasCholesterolCholesterol, DietaryCholesterol, HDLCholesterol, LDLCholesterol EstersCholesterol OxidaseCholesterol 7-alpha-HydroxylaseCholesterol, VLDLLipidsLipoproteinsTriglyceridesHypercholesterolemiaAnticholesteremic AgentsSterol O-AcyltransferaseLipoproteins, HDLSterolsHydroxymethylglutaryl CoA ReductasesApolipoprotein A-IBile Acids and SaltsEncyclopedias as TopicRhabdomyolysisCarbamazepineHeptanoic AcidsGemfibrozilPhenytoinPyrroles
DyslipidemiaHypertriglyceridemiaHypercholesterolemiaHeterozygousLipoproteinsDysbetalipoproteinemiaTriglycerideClassificationChylomicronsMetabolismLipidHyperlipoproteinemiaAdultsIncrease in high-density lipoprotein choPrimaryLipidsAtorvastatinHypertensionPhenotypesCardiovascular diseaseConcentrationsReduceDyslipidemiasApolipoproteinAbnormalityCoronaryBiosynthesisTotalType 2 diabetDiagnosisElevationsRisk of developing atheTriglycerides and cholesterolElevated low-density lipMorbidity and mortaDiseaseLiverTreatmentSecondaryMetabolicPatientsOccurSimvastatinReductaseIncreasesEstimation
Dyslipidemia9
  • Reduce elevated total cholesterol (total-C), low-density lipoprotein cholesterol (LDL-C), apolipoprotein B (Apo B), and triglycerides (TG), and to increase high-density lipoprotein cholesterol (HDL-C) in patients with primary hyperlipidemia (Fredrickson type IIa, heterozygous familial and nonfamilial) or mixed dyslipidemia (Fredrickson type IIb). (globalrph.com)
  • The primary uses of atorvastatin is for the treatment of dyslipidemia and the prevention of cardiovascular disease: Hypercholesterolemia (heterozygous familial and nonfamilial) and mixed dyslipidemia (Fredrickson types IIa and IIb) to reduce total cholesterol, LDL-C, apo-B, triglycerides levels, and CRP as well as increase HDL levels. (wikipedia.org)
  • familial and nonfamilial) or mixed dyslipidemia (Fredrickson type IIb). (medika.life)
  • Used as an adjunct to dietary therapy to treat primary hyperlipidemia (heterozygous familial and nonfamilial), mixed dyslipidemia and hypertriglyceridemia. (illnesshacker.com)
  • Reduce elevated total-C, LDL-C, apo B, and TG levels and increase HDL-C in adult patients with primary hyperlipidemia (heterozygous familial and nonfamilial) and mixed dyslipidemia ( 1.2 ). (nih.gov)
  • PURPOSE OF REVIEW: To provide an overview of recent advances that have defined the first putative genes behind familial combined hyperlipidemia, the most common genetic dyslipidemia and a major risk factor for early coronary heart disease . (symptoma.com)
  • The dyslipidemia commonly associated with T2DM is typified by elevated plasma triglycerides (TG), low high-density lipoprotein cholesterol (HDL-C) levels, and a preponderance of small, dense low-density lipoprotein (LDL) particles [ 3 ]. (biomedcentral.com)
  • To reduce elevated cholesterol and triglycerides in patient with mixed dyslipidemia (Fredrickson Type Ia and Ib). (com.bd)
  • Diabetic dyslipidemia is usually constituted by three concomitant plasma lipid alterations: elevation in the levels of triglycerides, a reduction in high-density lipoprotein (HDL) concentrations, and the predominance of atherogenic small dense low-density lipoproteins (LDL) [Krauss 2004]. (diabetologie-online.de)
Hypertriglyceridemia6
  • Reduce elevated TG in patients with hypertriglyceridemia (Fredrickson type lV hyperlipidemia). (globalrph.com)
  • Heterozygous familial hypercholesterolemia in children Homozygous familial hypercholesterolemia Hypertriglyceridemia (Fredrickson Type IV) Primary dysbetalipoproteinemia (Fredrickson Type III) Combined hyperlipidemia Primary prevention of heart attack, stroke, and need for revascularization procedures in people who have risk factors such as age, smoking, high blood pressure, low HDL-C, and a family history of early heart disease, but have not yet developed evidence of coronary artery disease. (wikipedia.org)
  • ANTARA is indicated as an adjunct treatment for hypercholesterolemia (high blood cholesterol) and hypertriglyceridemia (high triglycerides) in combination with diet. (salesandmarketingnetwork.com)
  • Hyperlipidemia comprises a heterogeneous group of disorders, characterized by high levels in one or more lipids and/or lipoproteins [atherogenic free fatty acids (FA), triglycerides (TG) (hypertriglyceridemia), small dense low-density lipoprotein cholesterol (LDL-C) (hypercholesterolemia), and apolipoprotein (apo) B], and/or low level in antiatherogenic high density lipoprotein cholesterol (HDL-C), in the circulation [ 1 - 3 ]. (hindawi.com)
  • Familial hypertriglyceridemia falls in the Fredrickson-Levy and Lee's (FLL) phenotypes . (mdwiki.org)
  • Familial hypertriglyceridemia separates itself from other dyslipidemias with significantly high triglycerides and low HDL levels. (mdwiki.org)
Hypercholesterolemia2
  • For example, if both hypercholesterolemia and mixed hyperlipidemia are documented in assessment then only one code should be coded, that is mixed hyperlipidemia. (rcmguide.com)
  • To reduce total and LDL-cholesterol concentrations patients with hypercholesterolemia associated with or exacerbated by diabetes mellitus or renal transplantation. (com.bd)
Heterozygous2
  • Ezetimibe and simvastatin tablets are indicated for the reduction of elevated total cholesterol (total-C), low-density lipoprotein cholesterol (LDL-C), apolipoprotein B (Apo B), triglycerides (TG), and non-high-density lipoprotein cholesterol (non-HDL-C), and to increase high-density lipoprotein cholesterol (HDL-C) in patients with primary (heterozygous familial and non-familial) hyperlipidemia or mixed hyperlipidemia. (tevapharm.com)
  • To reduce total cholesterol and LDL cholesterol in patients with heterozygous and homozygous familial hypercholesterolaemia. (com.bd)
Lipoproteins14
Dysbetalipoproteinemia1
  • Reduce elevated TG and VLDL-C in patients with primary dysbetalipoproteinemia (Fredrickson type lll hyperlipidemia). (globalrph.com)
Triglyceride9
  • Hyperlipidemia (ie, elevated plasma cholesterol or triglyceride levels or both) is present in all hyperlipoproteinemias. (medscape.com)
  • Plasma cholesterol levels are severely elevated, but plasma triglyceride levels are typically normal. (medscape.com)
  • In general if you have a high triglyceride level it is likely that your total cholesterol level will also be high, as well as your LDL cholesterol level. (noblehealthco.com)
  • People with a high triglyceride level usually have a low HDL level and are more at risk of a heart attack or stroke. (noblehealthco.com)
  • Risk factors for high triglyceride levels include obesity, smoking, alcohol consumption, physical inactivity, and a high carbohydrate diet. (noblehealthco.com)
  • In the quail group, plasma triglyceride (TG) and LDL-TG were significantly decreased, whereas the plasma cholesterol and HDL-C were unchanged. (jhsmr.org)
  • Serum Total Cholesterol (TC), Triglyceride (TG), High Density Lipoprotein Cholesterol (HDL-C) of the study subjects were measured using commercial kits and Low Density Lipoprotein Cholesterol (LDL-C) was calculated. (ijcrr.com)
  • For the treatment of patients with elevated serum triglyceride levels in hypertriglyceridaemia (Fredrickson Type IV). (com.bd)
  • But high triglyceride levels are linked with a higher risk of coronary artery disease. (cloudapp.net)
Classification5
  • Hyperlipidemia has been defined by the Fredrickson classification, which is based on beta-quantification, a process involving ultracentrifugation followed by electrophoresis. (medscape.com)
  • Indication: For the treatment of primary hyperlipidaemia types IIa, IIb, III, IV and V (Fredrickson classification) corresponding to groups I, II and III of the European Atherosclerosis Society guidelines - when diet alone or improvements in lifestyle such as increased exercise or weight reduction do not lead to an adequate response. (sdrugs.com)
  • Other classifications have been suggested, one of which is the National Cholesterol Education Program (NCEP) classification of lipoprotein disorders. (wikidoc.org)
  • In recent years, the understanding of the genetic and biochemical basis of these disorders has revealed a large and diverse group of diseases, many of which have similar clinical expressions, exposing the limitations of the Fredrickson classification system. (medscape.com)
  • Familial chylomicronemia syndrome (FCS) or type 1 hyperlipoproteinemia in the Fredrickson-Levy classification, comprises monogenetic disorders leading to significant fasting chylomicronemia. (diabetologie-online.de)
Chylomicrons3
  • ZOCOR has not been studied in conditions where the major abnormality is elevation of chylomicrons (i.e., hyperlipidemia Fredrickson types I and V). (globalrph.com)
  • Type I is a rare disorder characterized by severe elevations in chylomicrons and extremely elevated triglycerides, always reaching well above 1000 mg/dL and not infrequently rising as high as 10,000 mg/dL or more. (medscape.com)
  • Familial lipoprotein lipase deficiency is an example of a primary disorder in which a deficiency of lipoprotein lipase in tissue leads to a type I pattern of hyperlipidemia, with a massive accumulation of chylomicrons in the plasma. (medscape.com)
Metabolism5
  • Reduction of total cholesterols (TC) and LDL-C by dietary alterations and medications that affect lipid metabolism [ 14 ] is found to reduce the occurrence of atherosclerosis in animals and clinical cardiovascular events in human [ 15 ]. (hindawi.com)
  • Cholesterol Metabolism in Man. (noblehealthco.com)
  • The aim of this study was to investigate alterations in cholesterol metabolism during the perimenopausal transition that could increase the long-term risk of neurodegenerative disease in women, particularly Alzheimer's disease. (gremjournal.com)
  • Brain and serum cholesterol metabolism during chronological and endocrine aging were evaluated in rat models recapitulating the main characteristics of human perimenopause. (gremjournal.com)
  • Analysis of brain proteins involved in cholesterol metabolism showed export and clearance defects during endocrine aging and a decline in mobilization during post-menopausal chronological aging. (gremjournal.com)
Lipid13
  • Atorvastatin, sold under the brand name Lipitor among others, is a statin medication used to prevent cardiovascular disease in those at high risk and to treat abnormal lipid levels. (wikipedia.org)
  • Hyperlipidemia refers to increase in any type of lipid (fat) in blood. (rcmguide.com)
  • NCEP classifies lipid disorders according to laboratory cut off points for the levels of total cholesterol, LDL-C and HDL . (wikidoc.org)
  • Lipoprotein disorders must be initially classified broadly into hypolipidemias and hyperlipidemias corresponding to low or high lipid levels, respectively. (wikidoc.org)
  • Familial combined hyperlipidemia is an autosomal inherited lipid abnormality and one of the most common genetic dyslipidemias , whose features partly overlap with those of the metabolic syndrome . (symptoma.com)
  • Zestat (LIPID MODIFYING AGENTS) has not been studied in Fredrickson type I, III, IV, and V dyslipidemias. (pillintrip.com)
  • Hyperlipidemia, characterized by the abnormal blood lipid profiles, is one of the dominant factors of many chronic diseases such as diabetes, obesity, and cardiovascular diseases (CVD). (hindawi.com)
  • Higher serum TG levels appear to be significantly associated with DCI while other lipid parameters did not show any significant association. (surgicalneurologyint.com)
  • This may be due to their association with remnant cholesterol or free fatty acid-induced lipid peroxidation. (surgicalneurologyint.com)
  • There is also evidence of racial differences in lipid and lipoprotein levels, as black subjects have been found to have lower levels of triglycerides and higher levels of highdensity lipoprotein (HDL) cholesterol (11-21). (ijcrr.com)
  • Gemfibrozil is lipid regulating agent which decreases serum triglycerides and very low density lipoprotein (VLDL) cholesterol, and increases high density lipoprotein (HDL) cholesterol. (drugcentral.org)
  • Moderate reductions in total plasma cholesterol and low density lipoprotein cholesterol were observed for the gemfibrozil treatment group as whole, but the lipid response was heterogeneous, especially among different Fredrickson types. (drugcentral.org)
  • Instead the popular mythology is that the FHS confirmed both the Diet-Heart and Lipid Hypotheses because it found that those who ingested more dietary fat had higher blood cholesterol concentrations which in turn explained their higher rates of CHD. (thenoakesfoundation.org)
Hyperlipoproteinemia1
  • While modest decreases in total and low density lipoprotein (LDL) cholesterol may be observed with gemfibrozil therapy, treatment of patients with elevated triglycerides due to Type IV hyperlipoproteinemia often results in rise in LDL-cholesterol. (drugcentral.org)
Adults5
  • Some studies found evening dose of both short and long half-life statins was significantly superior to morning dose for lowering LDL-C. Geriatric: Plasma concentrations of atorvastatin in healthy elderly subjects are higher than those in young adults, and clinical data suggests a greater degree of LDL-lowering at any dose for people in the population as compared to young adults. (wikipedia.org)
  • Hypercholesterolaemia Atorvastatin Miklich is indicated as an adjunct to diet for reduction of elevated total cholesterol (total-C), LDL-cholesterol (LDL-C), apolipoprotein B, and triglycerides in adults, adolescents and children aged 10 years or older with primary hypercholesterolaemia including familial hypercholesterolaemia (heterozygous variant) or combined (mixed) hyperlipidaemia (Corresponding to Types IIa and IIb of the Fredrickson classification) when response to diet and other nonpharmacological measures is inadequate. (ravimiregister.ee)
  • 2013 ACC/AHA guideline on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk in adults: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. (jhsmr.org)
  • The aim of this study was to determine the predictors of diet and lifestyle-related CVD risk factors (total cholesterol, LDL, HDL, triglycerides, blood glucose and systolic and diastolic blood pressure) in adults residing in an urban district of Tehran. (who.int)
  • Atorvastatin is for prevention of cardiovascular disease in adults and hyperlipidemia. (drugs.com)
Increase in high-density lipoprotein cho1
  • In the primary prevention component of the Helsinki Heart Study, in which 4,081 male patients between the ages of 40 and 55 were studied in randomized, double-blind, placebo-controlled fashion, gemfibrozil therapy was associated with significant reductions in total plasma triglycerides and significant increase in high density lipoprotein cholesterol. (drugcentral.org)
Primary2
  • Familial LDL receptor deficiency and familial defective apoprotein B-100 are examples of primary defects that can lead to the accumulation of LDL, which corresponds to a type IIa pattern of hyperlipidemia. (medscape.com)
  • LDL-C is the primary transport carrier of cholesterol in the circulation. (biomedcentral.com)
Lipids4
Atorvastatin8
  • Like all statins, atorvastatin works by inhibiting HMG-CoA reductase, an enzyme found in the liver that plays a role in producing cholesterol. (wikipedia.org)
  • The SATURN trial which compared the effects of high-dose atorvastatin and rosuvastatin also confirmed these findings. (wikipedia.org)
  • There is evidence from systematic review and meta-analyses that statins, particularly atorvastatin, reduce both decline in kidney function (eGFR) and the severity of protein excretion in urine, with higher doses having greater effect. (wikipedia.org)
  • A meta-analysis of 21 RCTs confirmed that high dose (80 mg) atorvastatin therapy is more effective than regular dose or low dose statin therapy at preventing CI-AKI. (wikipedia.org)
  • The patient should continue on a standard cholesterol-lowering diet during treatment with atorvastatin. (biz.my)
  • Atorvastatin calcium has not been studied in Fredrickson Types I and V dyslipidemias. (nih.gov)
  • A higher incidence of hemorrhagic stroke was seen in patients without CHD but with stroke or TIA within the previous 6 months in the atorvastatin calcium 80 mg group vs. placebo ( 5.5 ). (nih.gov)
  • Atorvastatin lowers plasma cholesterol and lipoprotein levels by inhibiting HMG-CoA reductase and cholesterol synthesis in the liver and increases the number of hepatic LDL receptors on the cell surface for enhanced uptake and catabolism of LDL. (com.bd)
Hypertension1
  • Questions on history of smoking, diabetes, The aim of this study was to determine hypertension and hyperlipidaemia, family whether BAC detected by mammography, history of cardiovascular disease and use of already used as a screening test, has any medications were included. (who.int)
Phenotypes2
  • Traditionally, hyperlipidemias have been classified according to 6 phenotypes described by Fredrickson. (medscape.com)
  • Despite the system's shortcomings, Fredrickson phenotypes are a useful tool for the discussion of these disorders. (medscape.com)
Cardiovascular disease5
  • Prevention of cardiovascular disease Prevention of cardiovascular events in adult patients estimated to have a high risk for a first cardiovascular event (see section 5.1), as an adjunct to correction of other risk factors. (ravimiregister.ee)
  • Rosuvastatin is a member of the drug class of statins, used in combination with exercise, diet, and weight-loss to treat high cholesterol and related conditions and to prevent cardiovascular disease. (illnesshacker.com)
  • Rosuvastatin belongs to a class of medications called statins and is used to reduce plasma cholesterol levels and prevent cardiovascular disease. (illnesshacker.com)
  • In 2018, new Blood Cholesterol Guidelines were released, by the American College of Cardiology and American Heart Association Task Force on Clinical Practice Guidelines, which aim to reduce the risk of atherosclerotic cardiovascular disease through cholesterol management (Grundy, et. (cdc.gov)
  • LDL-C, non-HDL-C and ApoB levels are inter-correlated and all predict risk of atherosclerotic cardiovascular disease (ASCVD) in patients with type 2 diabetes mellitus (T2DM) and/or high TG. (biomedcentral.com)
Concentrations2
  • Decreased hepatic cholesterol concentrations stimulate the upregulation of hepatic low density lipoprotein (LDL) receptors which increases hepatic uptake of LDL. (illnesshacker.com)
  • Like saccharin, it has a slightly bitter aftertaste, especially at high concentrations. (w8mdspa.com)
Reduce3
  • Thus, prevention and treatment of hyperlipidemia are effective approaches to reduce the incident rate of chronic diseases. (hindawi.com)
  • Anzitor is indicated as an adjunct to diet to reduce elevated total cholesterol, LDL cholesterol, apolipoprotein B (Apo-B) and triglycerides levels in following diseases when response to diet and other non-pharmacological measures is inadequate. (com.bd)
  • To reduce cardiac ischaemic events in patients with asymptomatic or mild to moderate symptomatic coronary artery disease with elevated LDL-cholesterol level. (com.bd)
Dyslipidemias1
  • Ezetimibe and simvastatin tablets have not been studied in Fredrickson type I, III, IV, and V dyslipidemias. (tevapharm.com)
Apolipoprotein1
  • Cholesterol is bound to apolipoprotein B-100 as LDL in interstitial fluid. (medscape.com)
Abnormality1
  • The distribution of HDL subclasses have shown abnormality characterized by the lower HDL 2b (324.2 mg/L) contents and the higher preβ 1 -HDL (90.4 mg/L) contents for desirable TC Chinese subjects. (biomedcentral.com)
Coronary9
  • In patients with coronary heart disease (CHD) or at high risk of CHD, ZOCOR® can be started simultaneously with diet. (globalrph.com)
  • Myocardial infarction and stroke prevention in people with type 2 diabetes A 2014 meta-analysis showed high-dose statin therapy was significantly superior compared to moderate or low-intensity statin therapy in reducing plaque volume in patients with acute coronary syndrome. (wikipedia.org)
  • This finding of a low high-density lipoprotein (HDL) cholesterol level can be useful as an independent factor in assessing coronary artery disease (CAD) risk and further management. (medscape.com)
  • With regard to HA, the ATP III report stated, "Low HDL cholesterol is a strong independent predictor of CHD [coronary heart disease]. (medscape.com)
  • Long-term elevations of LDL cholesterol lead to a progressive accumulation of coronary atherosclerosis [ 2 ]. (biomedcentral.com)
  • NCEP ATP III defines the risk of developing coronary heart disease and other cholesterol related conditions, if under fasting, LDL-C less than 100mg/dL is the optimal goal for treatment. (noblehealthco.com)
  • Isolated Low Levels of High-Density Lipoprotein Cholesterol Are Associated With an Increased Risk of Coronary Heart Disease: An Individual Participant Data Meta-Analysis of 23 Studies in the Asia-Pacific Region. (noblehealthco.com)
  • Epidemiological studies have shown that both low HDL-cholesterol and high LDL-cholesterol are independent risk factors for coronary heart disease. (drugcentral.org)
  • The study involved subjects with serum non-HDL-cholesterol of over 200 mg/dL and no previous history of coronary heart disease. (drugcentral.org)
Biosynthesis4
  • This enzyme catalyzes the conversion of HMG-CoA to mevalonate, which is an early and rate-limiting step in the biosynthesis of cholesterol. (globalrph.com)
  • Furthermore, cholesterol biosynthesis is reduced by Zaf, which is accompanied by a stimulation of the LDL-receptor-mediated lipoprotein catabolism. (sdrugs.com)
  • HMG-CoA reductase catalyzes the conversion of HMG-CoA to mevalonic acid, the rate-limiting step in cholesterol biosynthesis. (illnesshacker.com)
  • Biosynthesis and biotransformation of cholesterol. (medmuv.com)
Total10
Type 2 diabet1
Diagnosis2
  • If the diagnosis of eruptive xanthomas is in doubt, obtaining a biopsy of the suspicious lesions will reveal accumulations of fat (not cholesterol). (medscape.com)
  • Hyperlipidemia: diagnosis and management. (jhsmr.org)
Elevations1
Risk of developing athe1
  • Heart disease and diet MEDICATIONS If lifestyle changes do not change your cholesterol levels, or you are at very high risk of developing atherosclerotic heart disease , your doctor may recommend medication. (symptoma.com)
Triglycerides and cholesterol1
Elevated low-density lip1
Morbidity and morta2
  • Strong epidemiological evidence links low levels of serum HDL cholesterol to increased CHD morbidity and mortality. (biomedcentral.com)
  • Subarachnoid hemorrhage (SAH) remains a serious disease with high morbidity and mortality, despite improvements in diagnostic modalities, better Intensive Care Unit (ICU) facilities, microsurgical, and endovascular advancements. (surgicalneurologyint.com)
Disease6
  • Lowering "bad" cholesterol and triglycerides and raising "good" cholesterol decreases the risk of heart disease and helps prevent strokes and heart attacks This drug can also lower the risk for heart attack or stroke in patients with diabetes . (medika.life)
  • This system does not take into account specific lipoprotein abnormalities (eg, low HDL-C or high LDL-C) that may contribute to disease despite normal cholesterol and TG levels. (msdmanuals.com)
  • Hyperlipidemia can occur due to food habit, secondary to any other underlying disease, genetic abnormalities or idiopathic (unknown cause). (rcmguide.com)
  • [1] [2] In this case, diabetes mellitus and metabolic syndrome would be widely considered a hyperlipidemic disease due to the array of cardiovascular and cerebrovascular sequelae that arise consequent to the chronic hyperlipidemia associated with the disease. (wikidoc.org)
  • Multivariate analysis using binary logistic regression adjusting for the effects of age, sex, systemic disease, World Federation of Neurosurgical Societies grade, Fisher grade, and clipping/coiling, revealed higher TG levels to have significant independent association with DCI ( P = 0.01). (surgicalneurologyint.com)
  • 14-15] By lowering plasma concentration of cholesterol, red yeast rice extract may help to prevent heart disease and associated complications. (noblehealthco.com)
Liver6
  • Cholesterol, specifically, is made in the liver . (medika.life)
  • In vivo studies in animals, and in vitro studies in cultured animal and human cells have shown rosuvastatin to have a high uptake into, and selectivity for, action in the liver, the target organ for cholesterol lowering. (illnesshacker.com)
  • HDL cholesterol - These are called "good cholesterol" because it transports part of LDL from blood to liver and it will be expelled from the body. (rcmguide.com)
  • In the peripheral tissues, particularly adipose and muscle tissue, VLDL is cleaved by lipoprotein lipase (LPL), extracting most of the triglycerides and forming an IDL that contains apoproteins B-100 and E. IDL can be taken up by the liver through the LDL receptor, or it can be converted to the cholesterol-rich LDL that contains apoprotein B-100. (medscape.com)
  • The main role of HDL is to accept cholesterol and to transport it back to the liver (reverse cholesterol transport). (medscape.com)
  • Cholesterol is a waxy, fat-like substance found in foods, and produced by our liver. (noblehealthco.com)
Treatment6
  • Treatment for isolated low HDL cholesterol is provided mainly to patients with CHD and CHD risk equivalents. (medscape.com)
  • There is a growing interest in TCM treatment of hyperlipidemia. (hindawi.com)
  • In the last few decades, hundreds of Chinese herbal medicines in the form of compounds, extracts, single herbs, or formulae have been reported to be effective for the prevention and treatment of hyperlipidemia [ 16 ], especially those high-fat diet (HFD) induced cases. (hindawi.com)
  • In November 2013, the American College of Cardiology and American Heart Association (ACC/AHA) released cholesterol guidelines which did not endorse LDL-C and non-HDL-C treatment goals [ 9 ], but this deletion has been rejected by several professional national and international societies [ 10 - 12 ]. (biomedcentral.com)
  • Data on health-related quality of life accrued from digitally engaged patients identified improvements among patients reporting high adherence to study treatment, but patient numbers were small. (jmir.org)
  • For the treatment of patients with dysbetalipoproteinaemia (Fredrickson Type III). (com.bd)
Secondary2
  • For example, in familial combined hyperlipidemia, expression may occur only in the presence of significant secondary causes. (msdmanuals.com)
  • The ATP III reported, "When a low HDL cholesterol is associated with high triglycerides (200-499 mg/dL), secondary priority goes to achieving the non-HDL cholesterol goal. (medscape.com)
Metabolic1
  • A high level may be a sign of metabolic syndrome . (cloudapp.net)
Patients1
  • The body mass index of patients with BAC was significantly higher than those without BAC. (who.int)
Occur1
Simvastatin1
  • High-dose simvastatin for aneurysmal subarachnoid hemorrhage: multicenter randomized controlled double-blinded clinical trial. (druglib.com)
Reductase3
  • Rosuvastatin selectively and competitively binds to and inhibits hepatic hydroxymethyl-glutaryl-coenzyme A (HMG-CoA) reductase, the enzyme which catalyzes the conversion of HMG-CoA to mevalonate, a precursor of cholesterol. (illnesshacker.com)
  • Rosuvastatin is a selective and competitive inhibitor of HMG-CoA reductase, the rate-limiting enzyme that converts 3-hydroxy-3-methylglutaryl coenzyme A to mevalonate, a precursor of cholesterol. (illnesshacker.com)
  • It works by blocking an enzyme (HMG-CoA reductase) necessary in the formation of cholesterol and by speeding up the catabolism of LDL from the blood. (noblehealthco.com)
Increases2
  • There was a trend towards greater increases in these correlations in the higher TG subgroup, non-significant possibly due to the small number of subjects. (biomedcentral.com)
  • Gemfibrozil increases levels of high density lipoprotein (HDL) subfractions HDL and HDL 3, as well as apolipoproteins AI and AII. (drugcentral.org)
Estimation1
  • Sample size was determined using a confidence interval of 95%, power of the study was 80%, attrition rate estimation 20% and an estimated rate of 13% for hyperlipidaemia. (who.int)