• Antibodies to ribosomal P2 protein were rarely detected, ransmission routes of human parvovirus 4 (PARV4), except in patients with systemic lupus erythematosus ( 5 ). (cdc.gov)
  • Therapeutic proteins (e.g., antibodies, vaccines, enzymes, cytokines, and growth factors) account for almost half of this market, followed by industrial proteins (e.g., technical enzymes) and research reagents (e.g., antibodies for protein detection and purification) ( Markets and Markets, 2017 ). (frontiersin.org)
  • From monoclonal antibodies and recombinant proteins to the most advanced cell and gene therapies, our comprehensive set of products and services will accelerate your workflows, reduce risk, and get you to the finish line faster. (sigmaaldrich.com)
  • Explore our vast selection of primary, secondary, and recombinant monoclonal antibodies for ELISA, Western blot, and immunohistochemistry (IHC). (sigmaaldrich.com)
  • The Western blot is a technique used to identify candidate hybrids, clones, subclones and monoclonal antibodies of interest that recognize and bind to one or more specific molecular weight proteins of interest. (mayo.edu)
  • Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. (abcam.com)
  • While some researchers have fused the IL2 moiety at the C-terminal extremity of the heavy chain or of the light chain of antibodies in full IgG format, these Oncotarget authors have preferred to use antibody fragments, as they may exhibit more favorable tumor: organ ratios and as those products may clear more rapidly from circulation, thus avoiding prolonged cytokine-related toxicity. (oncotarget.com)
  • Chimeric, Human and Humanized Anti-CSAP Monoclonal Antibodies - The present invention provides humanized, chimeric and human anti-CSAp antibodies and anti-CSAp antibody fusion proteins that are useful for the treatment and diagnosis of various cancers, including colon cancer. (patentsencyclopedia.com)
  • Disclosed herein are neutralizing monoclonal antibodies (MAbs) specific for the surface hemagglutinin (HA) protein of the influenza H5N1 strain. (justia.com)
  • A solution-phase binding assay (analyzed by size exclusion high performance liquid chromatography) between the intact mAbs and recombinant soluble ICAM-1 further established that the binding constants involving the Fab arms of the two antibodies were equivalent. (ox.ac.uk)
  • Antibodies are purified by protein A and peptide affinity chromatography. (cellsignal.com)
  • We show that 20-85% of these sera contain significant titers of antibodies against at least one of five frequently mutated and/or overexpressed tumor-associated proteins. (biomedcentral.com)
  • This assay should be generally useful for analyzing sera for antibodies recognizing any protein or its post-translational modifications. (biomedcentral.com)
  • Tests employing bacterial-produced proteins can produce high backgrounds because it is difficult to completely eliminate or block serum antibodies reactive with trace amounts of bacterial contaminants present in most antigen preparations, even in pharmaceutical grade preparations [ 3 ]. (biomedcentral.com)
  • In this dissertation, the goal was to enhance our knowledge on how new recombinant antibodies might be tailored to optimize localization to experimental tumors in mice. (projectsparadise.com)
  • Both single-chain variable fragments (scFv) antibodies or divalent tandem monospecific scFv [sc(Fv)2] antibodies with properties suitable for targeting were produced. (projectsparadise.com)
  • Bevacizumab and ranibizumab are closely-related recombinant humanized monoclonal antibodies that bind to VEGF. (baxkyardgardener.com)
  • A technology platform for the fast production of monoclonal recombinant antibodies against plant proteins and peptides. (stanford.edu)
  • The application of recombinant antibodies in plant biology research is limited because plant researchers have minimal access to high-quality phage display libraries. (stanford.edu)
  • We are convinced that this antibody platform will further stimulate applications of recombinant antibodies such as the diagnostic detection or immunomodulation of specific antigens in plants. (stanford.edu)
  • We have developed a comprehensive array of ELISAs to study poxvirus-induced antibodies, utilising 24 MPXV and 3 Vaccinia virus (VACV) recombinant antigens. (cdc.gov)
  • Methods and Compositions for F-18 Labeling of Proteins, Peptides and Other Molecules - The present application discloses compositions and methods of synthesis and use of F-18 labeled molecules of use, for example, in PET imaging techniques. (patentsencyclopedia.com)
  • In particular embodiments, the labeled molecules may be peptides or proteins, although other types of molecules including but not limited to aptamers, oligonucleotides and nucleic acids may be labeled and utilized for such imaging studies. (patentsencyclopedia.com)
  • 272-630 and aa 604-914 of ORF2, were fused to bacterial and Chien-Ching Hung small ubiquitin-like modifi er (SUMO) protein (a member of a ubiquitin-like protein family) and used as antigens in In studying the epidemiology of parvovirus 4 (PARV4) immunoblot. (cdc.gov)
  • It is the smallest antibody fragment with antigen binding activity, with small molecular weight and strong affinity and specificity for corresponding antigens, It can be mass produced through genetic engineering technology. (dia-an.com)
  • The obtainment of transgenic edible plants carrying recombinant antigens is a desired issue in search for economic alternatives viewing vaccine production. (scielo.br)
  • This method is based on fusing protein antigens to an enzyme reporter, Renilla luciferase (Ruc), and expressing these fusions in mammalian cells, where mammalian-specific post-translational modifications can be added. (biomedcentral.com)
  • Investigators must use their own laboratory assay system, which should be perfected a minimum of two weeks prior to fusion, specifically designed for their antigen and experimental application. (mayo.edu)
  • However, one of the factors that make it difficult and raise the price of production in every system consists in the purification process of the recombinant antigen. (scielo.br)
  • Thus, striking improvements in recombinant antigen were achieved by alternative polyadenylation signals and fusion proteins containing targeting signals designed to enhance integration or retention of HBsAg in the endoplasmic reticulum (ER) of plant cells [6]. (scielo.br)
  • Proliferating cell nuclear antigen (PCNA) is a member of the DNA sliding clamp family of proteins that assist in DNA replication (6). (cellsignal.com)
  • After mixing crude extracts, sera and protein A/G beads together and incubating, during which the Ruc-antigen fusion become immobilized on the A/G beads, antigen-specific antibody is quantitated by washing the beads and adding coelenterazine substrate and measuring light production. (biomedcentral.com)
  • Such proteins can be expressed recombinantly and still maintain the antigen-binding characteristics of IgG's. (proteinmods.com)
  • The scFvs selected from the library against a diverse set of plant proteins showed moderate to high antigen-binding affinity together with high specificity. (stanford.edu)
  • JR-441 is a recombinant fusion protein of antibody fragment against the human transferrin receptor and heparan N- sulfatase, the enzyme missing or malfunctioning in subjects with MPS IIIA. (qlifepro.com)
  • The Fc domain of IgG contributes several important properties to the fusion protein, including increased half-life in the bloodstream, enhanced binding to Fc receptors on immune cells, and the ability to activate complement. (wikipedia.org)
  • The agent specifically binds to IL-2 receptors on the cell surface, causing diphtheria toxin fragments that have entered cells to inhibit protein synthesis. (pipelinereview.com)
  • Type â enveloped viruses bind to cell receptors through surface glycoproteins to initiate infection or undergo receptor-mediated endocytosis and initiate membrane fusion in the acidic environment of endocytic compartments, releasing genetic material into the cell. (bvsalud.org)
  • Market growth has been supported by advances in recombinant protein production technologies, including the engineering of expression hosts, the optimization of upstream cultivation (e.g., bioreactor design, nutritional, and physical parameters), and the development of more efficient protein extraction and purification methods. (frontiersin.org)
  • In addition, DDDDK is a part of the octapeptide FLAG tag (DYKDDDDK), which can be utilized as a fusion tag for recognition by antibody, and for detection of fusion protein expression with Western blot analysis, as well as for purification of the fusion protein by Anti-FLAG affinity chromatography. (abmgood.com)
  • Moreover, to optimize an scFv as immunodetection agent, two expression systems that allow efficient production and purification of bivalent scFv-Fc and scFv-CkappaZIP fusion proteins were integrated. (stanford.edu)
  • LYMPHIR is a recombinant fusion protein that combines the interleukin-2 (IL-2) receptor binding domain with diphtheria toxin fragments. (pipelinereview.com)
  • E7777, a recombinant cytotoxic fusion proteins comprising diphtheria toxin fragments A and B and individual interleukin\2, stocks an amino acidity series with denileukin diftitox but provides improved purity and an elevated percentage of dynamic proteins monomer species. (acancerjourney.info)
  • The protein is a fusion of the extracellular domain of the CD4 receptor and the Fc domain of human immunoglobulin G (IgG), the most abundant antibody isotype in the human body. (wikipedia.org)
  • Recombinant fusion proteins containing the receptor protein fragment of interest fused to a truncated mouse Fc domain and a unique biotinylation signal are produced, biotinylated, and coupled to (strept) avidin-coated fluorescent or paramagnetic microspheres. (archive.org)
  • Aflibercept, a recombinant fusion protein that acts as a decoy receptor for VEGF, is usually another anti-VEGF therapy approved for the treatment of nAMD[9]. (baxkyardgardener.com)
  • Non-lytic: Acts as a long lasting fusion protein which only binds to the receptor. (adipogen.com)
  • Tienen un empleo potencial en el tratamiento del SIDA ya que poseen propiedades de unión a gp120 y de bloqueo del VIH de rCD4 así como una gran semivida plasmática y funcioones de unión al receptor Fc de la inmunoglobulina. (bvsalud.org)
  • If the mice are immunized by the core, no further action is needed by the investigator prior to fusion. (mayo.edu)
  • However, mice that are not immunized by the core are required to be certified as "mouse virus-free" prior to fusion. (mayo.edu)
  • Investigators who need rat or rabbit fusions performed must provide spleens or lymph nodes to the core on the day of the fusion, as the core only immunizes and houses mice. (mayo.edu)
  • A comparative quantitative biodistribution analysis in tumor-bearing mice using radioiodinated proteins revealed that the novel format exhibited the best biodistribution results. (oncotarget.com)
  • CD4 immunoadhesin is a recombinant fusion protein consisting of a combination of CD4 and the fragment crystallizable region, similarly known as immunoglobulin. (wikipedia.org)
  • Fluorescein isothiocyanate (FITC) conjugated to protein A or G binds to the fragment crystallizable region of IgG immunoglobulins, especially IgG2a. (mayo.edu)
  • The protein has also inspired the development of other immunoadhesin molecules, such as CD4-IgG2 and CD4-mimetic compounds, which are being investigated as potential therapies for HIV/AIDS. (wikipedia.org)
  • Proteins are therefore molecules of great complexity and near infinite diversity, making them suitable for many different applications. (frontiersin.org)
  • Chimeric molecules resulting from the fusion of recombinant soluble CD4 to the Fc portion of immunoglobulins. (bvsalud.org)
  • This library represents a selection of drug-like compounds aimed at modulating protein-protein interaction (PPI) of β-catenin with different proteins involved in significant physiological processes. (chemdiv.com)
  • Its product, podocin, is a new member of the stomatin family, which consists of hairpin-like integral membrane proteins with intracellular NH2- and COOH-termini. (jci.org)
  • This led us to construct recombinant DNA plasmids containing the encoding sequence of HBsAg and the same construction fused with the SEQDEL sequence responsible for ER sorting. (scielo.br)
  • That podocin interacts with CD2AP and nephrin in vivo is shown by coimmunoprecipitation of these proteins from glomerular extracts. (jci.org)
  • Dyadic has created a proprietary protein expression platform based on a genetically modified strain of fungus called C1 that may be able to produce proteins in higher amounts and at a lower cost than CHO cells. (manufacturingchemist.com)
  • Not to use synthetic biology technologies to modify hyper-productive, industrially proven cells to produce proteins that have similar characteristics, with a potentially similar safety profile and efficacies, is ignoring the incredible scientific breakthroughs and advances that are occurring faster in biopharma than Moore's Law did for tech. (manufacturingchemist.com)
  • Small or large scale: From a simple Erlenmeyer flask to our largest fermenter (70 liters) we produce proteins in quantities ranging from milligram to kilogram. (proteinmods.com)
  • Only the COOH-terminal fusion protein (C-term) was recognized by the antibody. (jci.org)
  • The protein-bound membrane is then incubated with a known or test antibody reagent, followed by a secondary antibody conjugated with a color indicator enzyme or substrate (or radiolabeled isotope). (mayo.edu)
  • Caspase-3 (CPP-32, Apoptain, Yama, SCA-1) is a critical executioner of apoptosis, as it is either partially or totally responsible for the proteolytic cleavage of many key proteins such as the nuclear enzyme poly (ADP-ribose) polymerase (PARP) (1). (cellsignal.com)
  • It is not generally necessary to deactivate the EK enzyme, however to prevent further degradation of the target protein after the reaction is finished, removal of enterokinase via affinity chromatography is recommended. (abmgood.com)
  • Author Manuscript and RNA repair protein AlkB-derived enzyme mixture was first used to remove methylations at the Watson-Crick face. (cdc.gov)
  • Since 1987 two recombinant vaccines produced into Saccharomices cerevisiae cells by Sharp & Dhome and Smith Kline Beechmam have been utilized for HBV immunization. (scielo.br)
  • We applied an immunoprecipitation assay to demonstrate protein interaction between EPAC1 and LC2 in co-transfected human embryonic kidney 293 cells. (hw.ac.uk)
  • LC2 was found to interact with a glutathione-S-transferase-fusion protein of the cAMP-binding domain of EPAC1 in a pull-down assay, but not the DEP, REM (Ras exchange motif) or CAT (catalytic) domains. (hw.ac.uk)
  • In our recently developed assay based on a recombinant VACV expressing secreted Gaussia luciferase, they both exhibited high potency in inhibiting VACV replication with EC(50)s in the low nanomolar range. (cdc.gov)
  • Objective: To investigate the effects of prion protein 106-126 peptide on inducing apoptosis in differentiated PC12 cells. (researchgate.net)
  • Methods: After differentiated by nerve growth factor (NGF), the PC12 cells were infected by prion protein 106-126 peptide. (researchgate.net)
  • Conclusion: Prion protein 106-126 peptide can induce apoptosis in differentiated PC12 cells and present cellular toxicity definitely. (researchgate.net)
  • We previously identified a lipopeptide, EK1C4, by linking cholesterol to EK1, a pan-CoV fusion inhibitory peptide via a polyethylene glycol (PEG) linker, which showed potent pan-CoV fusion inhibitory activity. (bvsalud.org)
  • In the process of membrane fusion, envelope protein exposes fusion peptide, followed by an insertion into the cell membrane or endosomal membrane. (bvsalud.org)
  • The core substitution A71L impaired T immunogenicity of the target epitope within the protein, but not in the peptide, whereas the N73A substitution impaired the responses in both instances. (aber.ac.uk)
  • Monoclonal antibody is produced by immunizing animals with a recombinant Protein A-PCNA fusion protein, or with a synthetic peptide corresponding to residues surrounding Cys60 of human Survivin. (cellsignal.com)
  • Unlike other site-specific proteases that cut within the recognition sequences leaving extra amino acids in the cleaved peptide products, the EK1 cleaves after the C-terminal end of the lysine residue, and the fragment produced from the cleavage reaction does not inherit any residues from the DDDDK recognition sequence. (abmgood.com)
  • Single chain variable fragment (scFv) is a recombinant protein formed by splicing the antibody heavy chain variable region (VH) gene and light chain variable region (VL) gene through flexible linker. (dia-an.com)
  • Initially announced in January 2018, this acquisition strengthens Sanofi's position in hematology and specialty medicines by adding Bioverativ's Eloctate (recombinant fusion protein composed of human immunoglobulin[IG] G1-Fc linked cleavage factor VIII) and Alprolix (recombinant fusion protein composed of IX coagulation factor IX Fc fragment of IgG1) for the treatment of hemophilia A and hemophilia B, respectively, to Sanofi's hemophilia portfolio. (biopharminternational.com)
  • Factor IX is the treatment of choice for acute hemorrhage or presumed acute hemorrhage in patients with hemophilia B. Recombinant factor IX is the preferred source for replacement therapy. (medscape.com)
  • We report the in vivo pharmacokinetics of a broad-spectrum vaccinia virus CC chemokine binding protein (35 K) fused to human IgG1 Fc. (ox.ac.uk)
  • In current practice, bone grafting and instrumentation are often used concurrently based on the expectation that internal fixation of spine enhances the success of bone fusion while a successful bone fusion eliminates the possibility of hardware failure by reducing the chronic biomechanical stresses on the hardware construct. (medscape.com)
  • Recombinant protein fragment of Human FZR1 with N-terminal His6ABP (ABP = Albumin Binding Protein derived from Streptococcal Protein G) fusion tag. (sigmaaldrich.com)
  • Most of the amino acid exchanges between human and mouse are restricted to the NH 2 -terminal part of the protein, whereas the tm domain, the stomatin signature, and the COOH-terminal part are almost identical. (jci.org)
  • In this study, we found that EKL1C also exhibited broad-spectrum fusion inhibitory activity against human immunodeficiency virus type 1 (HIV-1) infection by interacting with the N-terminal heptad repeat 1 (HR1) of viral gp41 to block six-helix bundle (6-HB) formation. (bvsalud.org)
  • At the time, they wanted to produce a protein that had a certain glycan structure, which looked more human, and, subsequently, the world then became embedded with and wedded to a cell line that really isn't that efficient. (manufacturingchemist.com)
  • This technology is based on our previously published studies showing that a Ruc fusion with a human protein retain the biological activities of both the reporter and the human protein and can be used to detect weak protein-protein interactions [ 4 ]. (biomedcentral.com)
  • Therefore, we constructed a library of 1.3 x 10(10) clones displaying human single-chain variable fragments (scFvs) that is available to the academic community. (stanford.edu)
  • Using EPAC1 (exchange protein directly activated by cAMP 1) as bait in two-hybrid screens of foetal and adult human brain libraries, we identified the LC2 (light chain 2) of MAP1A (microtubule-associated protein 1A) as a protein capable of interaction with EPAC1. (hw.ac.uk)
  • Over the last three decades, the expression of recombinant proteins in plants and plant cells has been promoted as an alternative cost-effective production platform. (frontiersin.org)
  • Here, we discuss the strengths of plant expression systems for specific applications, but mainly address the bottlenecks that must be overcome before plants can compete with conventional systems, enabling the future commercial utilization of plants for the production of valuable proteins. (frontiersin.org)
  • Even so, plants as an alternative expression platform offer unique advantages, particularly when target proteins are difficult to produce in conventional systems, require specific qualitative properties such as particular glycan profiles, and/or must be produced on a larger scale in response to urgent demand. (frontiersin.org)
  • The roles of b-catenin are 'classically' defined: as an adhesion protein and as a signaling protein, transducing extracellular signals to the nucleus to modify gene expression. (chemdiv.com)
  • We demonstrate that the in vivo efficacy of the protein can be interrogated using hydrodynamic gene delivery of a standard mammalian expression plasmid. (ox.ac.uk)
  • the expression levels of protein associated with apoptosis and endoplasmic reticulum stress (ERS) of SKO-007 cells in various groups were detected by Western blotting method. (researchgate.net)
  • In conclusion, immunological analysis of mutated proteins revealed functional associations between topographically distinct antigenic determinants which may account for the previously observed differences in the specificity of immune responses between immunised and infected hosts. (aber.ac.uk)
  • More than 300 protein-based medicines have been approved in the USA and Europe, and proteins account for almost a third of all pharmaceuticals in development ( Walsh, 2018 ). (frontiersin.org)
  • The function of a protein is determined by the number and sequence of amino acids, which controls the three-dimensional structure of the resulting folded polypeptide. (frontiersin.org)
  • A particle according to any one of the preceding claims, wherein heterologous polypeptide sterically hinders fusion of an enveloped viral particle with an eukaryotic cell to which it is bound. (sumobrain.com)
  • The fusion process involves fusing spleen or lymph node cells with a myeloma fusion partner cell line. (mayo.edu)
  • Some of the new approaches depend on tumor biology and aim specifically to inhibit tumor growth and metastasis by targeting the tumor microenvironment or vasculature (leaving normal cells unaffected) or focusing on specific protein or signal transduction pathways. (medscape.com)
  • Oncotarget recently published " A novel format for recombinant antibody-interleukin-2 fusion proteins exhibits superior tumor-targeting properties in vivo which reported that here, the authors describe four novel formats for the L19-IL2 fusion, featuring different arrangements of antibody and IL2. (oncotarget.com)
  • Mutations to the complement (C1q) and FcgR I binding sites of the IgGs Fc fragment render the fusion proteins incapable of antibody directed cytotoxicity (ADCC) and complement directed cytotoxicity (CDC). (adipogen.com)
  • β-Catenin is a fascinating protein with many important cellular and developmental functions. (chemdiv.com)
  • β -catenin has many binding partners that mediate a diverse set of cellular functions, and the protein probably acts as a 'hub' on which many cellular signaling networks impinge. (chemdiv.com)
  • fms-related tyrosine kinase 4, encoding VEGFR3, and gap junction proteins gamma-2, encoding connexin-47, CX47, respectively) code for proteins localized on the cellular BAY 63-2521 distributor membrane. (acancerjourney.info)
  • It might be a perfect model to study the cellular toxicity of prion protein. (researchgate.net)
  • In some instances, the desired protein comprised 50% of total cellular protein. (proteinmods.com)
  • Further conformational changes ensue in which the type 1 envelope protein forms a typical six-helix bundle structure, shortening the distance between viral and cell membranes so that fusion can occur. (bvsalud.org)
  • HBsAg is the abundantly expressed envelope protein as a dimmer of two identical polypeptides encoded by the same gene. (scielo.br)
  • Enzymatic deamidation is a promising approach in enhancing the solubility of myofibrillar proteins (MPs) in water paving the way of tailor manufacturing muscle protein-based beverages. (bvsalud.org)
  • In another embodiment, the neutralizing antibody is a monoclonal antibody such as a mouse antibody, a humanized antibody, a chimeric antibody, or a fragment thereof. (justia.com)
  • a recombinant protein synthesized from in vitro methods may also be used. (mayo.edu)
  • For example, the fusion protein has been shown to induce the production of cytokines, such as interleukin-2 (IL-2) and interferon-gamma (IFN-γ), which are important for the activation and proliferation of immune cells. (wikipedia.org)
  • CD4 immunoadhesin is a bifunctional protein that has the ability to block HIV infection, inhibit autoreactive T-cell activation, and potentially modulate immune responses. (wikipedia.org)
  • The BdCBF proteins possess transcriptional activation activity and bind directly to the promoters of the target genes. (biomedcentral.com)
  • Activation of caspase-3 requires proteolytic processing of its inactive zymogen into activated p17 and p12 fragments (2). (cellsignal.com)
  • It is highly specific for cleaving fusion proteins with the recognition sequence, Asp-Asp-Asp-Asp-Lys (DDDDK). (abmgood.com)
  • Therefore, the application can be extremely advantageous for producing a 100% native protein sequence and structure from recombinant fusion protein, which has the desired product immediately after the enterokinase recognition sequence, DDDDK. (abmgood.com)
  • The Enterokinase will also be able to cleave the tag if it is placed at the c-terminus, however please be aware that this will result in the recogition sequence being left intact on your protein of interest, even after the his tag has been removed. (abmgood.com)
  • We will sequence promising clones to validate protein sequence. (proteinmods.com)
  • We also offer the use of degenerate primers and microscale production if you wish to optimize your protein sequence. (proteinmods.com)
  • Hyperimmune mouse serum raised against purified, recombinant OmpP4 did not promote bactericidal killing of 35000HP or phagocytosis by J774A.1 mouse macrophages in serum bactericidal and phagocytosis assays, respectively. (biomedcentral.com)
  • The protein is transferred to a nitrocellulose or polyvinylidene difluoride absorbing membrane sheet. (mayo.edu)
  • encodes a putative lipoprotein, designated outer membrane protein P4 (OmpP4). (biomedcentral.com)
  • This review focuses on entry inhibitors that target the six-helical bundle core against highly pathogenic enveloped viruses with class I fusion proteins, including retroviruses, coronaviruses, influenza A viruses, paramyxoviruses, and filoviruses. (bvsalud.org)
  • These results suggest that HR1 is a common target for the development of broad-spectrum viral fusion inhibitors and EKL1C has potential clinical application as a candidate therapeutic or preventive agent against infection by coronavirus, HIV-1, and possibly other class I enveloped viruses. (bvsalud.org)
  • We employ a proprietary E.coli strain designed specifically for protein production. (proteinmods.com)
  • Hydrodynamic Gene Delivery of CC Chemokine Binding Fc Fusion Proteins to Target Acute Vascular Inflammation In Vivo. (ox.ac.uk)
  • High plasma levels of the 35 K-Fc protein are maintained for at least 14 days post gene transfer, with the protein still detectable at 5 weeks. (ox.ac.uk)
  • A fusion of light and heavy chain immunoglobulin components is called a single-chain antibody, or single-chain variable fragment. (proteinmods.com)
  • Each antibody in the SignalStain ® Proliferation/Apoptosis IHC Sampler Kit detects endogenous levels of its target protein and does not cross-react with any related proteins. (cellsignal.com)