• The localization of antigen in lymph nodes and its relation to specific antibody-producing cells. (wikidata.org)
  • The localization of antigen in relation to specific antibody-producing cells. (wikidata.org)
  • Localization of circulating antigen-antibody complexes in vessels of guinea pigs by means of anaphylactic shock was found to be mediated by histamine that was released at the time of anaphylaxis. (silverchair.com)
  • Rat anaphylatoxin was found to cause vascular localization and symptoms of anaphylaxis identical with that brought about by antigen-antibody anaphylaxis. (silverchair.com)
  • Antibody against Forssman antigen in the vessel walls of the guinea pigs also led to deposition of circulating complexes. (silverchair.com)
  • or actively by prior immunization of the recipient with graft antigens which evoke specific antibodies and form antigen-antibody complexes which bind to the antigen receptor sites of the T-cells and block their cytotoxic activity. (lookformedical.com)
  • The stimulus for production of this antibody is likely a form of molecular mimicry in which a microorganism's antigen shares structural similarity to the P antigen on human RBCs, resulting in immunogenic cross-reactivity. (medscape.com)
  • Debate Sheep erythrocytes are ideal for searching for individual anti-Forssman antibody. (neighborhoodhousecharterschool.org)
  • In the populace (n=800) studied right here, we found one person missing the anti-Forssman antibody. (neighborhoodhousecharterschool.org)
  • The Forssman antigen is distinct from the Paul-Bunnell antigen, antibodies to which are diagnostic of glandular fever (infectious mononucleosis). (wikipedia.org)
  • Antigens stimulating the formation of, or combining with heterophile antibodies. (nih.gov)
  • The number of anti-Forssman antibodies in plasma is normally higher in females than in men. (neighborhoodhousecharterschool.org)
  • The Forssman antigen is a glycolipid heterophil protein and a type of heterogenetic antigen found in certain animals like dogs, horses, cats, turtles and sheep, and enteric organisms such as pneumococci. (wikipedia.org)
  • A new histo-blood group system was discovered, based on the identification of Forssman glycolipid antigen on human red blood cells. (ashpublications.org)
  • Cryptic promoters within transposable elements (TEs) can be transcriptionally reactivated in tumors to create new TE-chimeric transcripts, which can produce immunogenic antigens. (bvsalud.org)
  • Nevertheless, Yamamoto discovered that reversion of two inactivating missense mutations in the individual gene (c.688G>A [p.Gly230Ser] and c.887A>G [p.Gln296Arg]) fully restored glycosyltransferase activity allowing the formation of Fs antigen genes in Fs-positive types8. (neighborhoodhousecharterschool.org)
  • Anti-A(EC) has no ability to release the cellfixed anti-Forssman haemolysin and the cell-fixed blood group A-decomposing enzyme. (karger.com)
  • A newly described polymorphism in the GBGT1 gene activates the encoded enzyme to synthesize Forssman antigen. (ashpublications.org)
  • In sheep, it is found on erythrocytes but not on tissue and organs, unlike hamsters and guinea pigs whose organ cells do carry the antigen. (wikipedia.org)
  • The unexpected Fs antigen was confirmed in structural, serologic, and flow-cytometric studies. (ashpublications.org)
  • We have previously demonstrated that the C-type lectin macrophage galactose-type lectin (MGL), expressed by human antigen presenting cells, can distinguish healthy tissue from CRC through its specific recognition of Tn antigen. (oncotarget.com)
  • Elevated cell-surface expression of truncated carbohydrate structures such as Tn antigen (GalNAcα-Ser/Thr) is frequently observed during tumor progression. (oncotarget.com)
  • The Fs antigen exists in several types of individual cancer tumor, including gastric, digestive tract, and lung malignancies9,10. (neighborhoodhousecharterschool.org)
  • We performed a comprehensive screen for these TE exaptation events in 33 TCGA tumor types, 30 GTEx adult tissues and 675 cancer cell lines, and identified 1,068 TE-exapted candidates with the potential to generate shared tumor-specific TE-chimeric antigens (TS-TEAs). (bvsalud.org)
  • An immune response with both cellular and humoral components, directed against an allogeneic transplant, whose tissue antigens are not compatible with those of the recipient. (lookformedical.com)
  • Antigens that exist in alternative (allelic) forms in a single species. (lookformedical.com)
  • Transplantation between genetically identical individuals, i.e., members of the same species with identical histocompatibility antigens, such as monozygotic twins, members of the same inbred strain, or members of a hybrid population produced by crossing certain inbred strains. (lookformedical.com)
  • They are cross-reacting antigens found in phylogenetically unrelated species. (nih.gov)
  • Donor and recipient pairs should be of identical ABO blood group, and in addition should be matched as closely as possible for HISTOCOMPATIBILITY ANTIGENS in order to minimize the likelihood of allograft rejection. (lookformedical.com)
  • It may be nonspecific as in the administration of immunosuppressive agents (drugs or radiation) or by lymphocyte depletion or may be specific as in desensitization or the simultaneous administration of antigen and immunosuppressive drugs. (lookformedical.com)
  • Identification of the major histocompatibility antigens of transplant DONORS and potential recipients, usually by serological tests. (lookformedical.com)
  • Both antigens are present on the red blood cells of horse and sheep but guinea pig kidney cells have only the Forssman antigen. (wikipedia.org)
  • In analogy with histo-blood group A antigen, Forssman (Fs) antigen terminates with α3- N -acetylgalactosamine and can be used by pathogens as a host receptor in many mammals. (ashpublications.org)
  • Typical isoantigens are the BLOOD GROUP ANTIGENS. (lookformedical.com)
  • Ono showed the current presence of Fs antigen in the cytoplasm of digestive tract goblet cells, Oxolamine citrate those in the so-called transitional mucosa next to carcinoma specifically, from 69 of 70 sufferers with digestive tract cancer tumor9. (neighborhoodhousecharterschool.org)
  • National data are inclusive of influenza cases diagnosed by antigen detection, nucleic acid testing, and viral isolation. (cdc.gov)
  • The results show that relative to other carbohydrate antigens examined, GalNAca1-3Gal is expressed at high levels in squamous carcinomas of the cervix. (nih.gov)
  • The Forssman antigen is a glycolipid heterophil protein and a type of heterogenetic antigen found in certain animals like dogs, horses, cats, turtles and sheep, and enteric organisms such as pneumococci. (wikipedia.org)
  • The D-L antibody is known to bind to various antigens such as I-, i-, p-, Pr-, on the RBC surface, but the glycosphingolipid P antigen is considered its primary target. (medscape.com)
  • Only monoclonal antibody known to bind the GalNAca1-3Gal antigen but no other closely related structures, including blood group A, the Forssman antigen, and the Tn antigen. (nih.gov)
  • National data are inclusive of influenza cases diagnosed by antigen detection, nucleic acid testing, and viral isolation. (cdc.gov)
  • Immunoglobulins produced in response to VIRAL ANTIGENS. (lookformedical.com)
  • They are the main antigenic components of the Wassermann-type antigen that is used in nontreponemal SYPHILIS SERODIAGNOSIS. (lookformedical.com)
  • Börjeson's syndrome , Börjeson-Forssman-Lehmann syndrome a hereditary syndrome, transmitted as an X-linked recessive trait, characterized by severe mental retardation, epilepsy, hypogonadism, hypometabolism, marked obesity, swelling of the subcutaneous tissues of the face, and large ears. (topgrowupclinic.eu)
  • Previous studies examining Tn antigen levels present in cervical cancer tumors have produced conflicting results. (nih.gov)
  • Test results for leptospiral antigen by immunohistochemistry were positive in eight cases with no direct relationship between antigen deposits in the pulmonary vascular endothelium and intensity of the lesions. (nih.gov)