Receptor, Endothelin AReceptors, EndothelinReceptor, Endothelin BEndothelinsEndothelin-1Endothelin-3Endothelin-2Amino Acid SequencePeptides, CyclicMolecular Sequence DataViper VenomsPhenylpropionatesKineticsBase SequenceSulfonamidesCattleVasoconstrictionPyrrolidinesBinding SitesCloning, MolecularAspartic Acid EndopeptidasesPeptide FragmentsCalciumChromatography, High Pressure LiquidRNA, MessengerHydrogen-Ion ConcentrationMolecular WeightAzepinesEscherichia coliPeptidesElectrophoresis, Polyacrylamide GelSequence Homology, Amino AcidProtein ConformationOxidation-ReductionRabbitsIndansOligopeptidesRats, Inbred StrainsVasoconstrictor AgentsMitochondria, LiverLiverPiperidinesMacromolecular SubstancesRats, WistarMetalloendopeptidasesChemistryAmino AcidsChemical PhenomenaRecombinant ProteinsEnzyme ActivationAdenosine TriphosphatePhotosynthetic Reaction Center Complex ProteinsBlood PressureSwineCytochrome b GroupProton-Translocating ATPasesBinding, CompetitiveProtonsRats, Sprague-DawleyCell MembraneElectron Spin Resonance SpectroscopyAntihypertensive AgentsEndothelium, VascularDNAHemeMagnetic Resonance SpectroscopyCells, CulturedDNA, ComplementaryHydrolysisMutagenesis, Site-DirectedCalmodulinLight-Harvesting Protein ComplexesUncoupling AgentsSubstrate SpecificityProtein Kinase CChlorophyllPlantsMutationPhotosystem II Protein ComplexRod Cell Outer SegmentProtein BindingMuscle, Smooth, VascularCytosolSpectrophotometryStructure-Activity RelationshipPhosphorylationCysteineTrypsinElectron Transport Complex IVHypertension, PulmonaryModels, MolecularProtein PrecursorsOxidoreductasesBlotting, NorthernIsoenzymesTime FactorsSequence Homology, Nucleic AcidDose-Response Relationship, DrugElectron TransportHemodynamics