• Chemokine mRNA expression in gastric mucosa is associated with Helicobacter pylori cagA positivity and severity of gastritis. (bmj.com)
  • AIM: To investigate the association between the quantity of gastric chemokine mRNA expression, severity of gastritis, and cagA positivity in Helicobacter pylori associated gastritis. (bmj.com)
  • Warren JR, Marshall B. Unidentified curved bacilli on gastric epithelium in active chronic gastritis. (medscape.com)
  • Analysis of whole genomic expression profiles of Helicobacter pylori related chronic atrophic gastritis with IL-1B-31CC/-511TT genotypes. (medscape.com)
  • Based on gastric and duodenal endoscopy as well as on histopathologic and immunomorphologic examination of biopsy specimens we assessed the incidence of gastritis in children with collagenosis. (medscimonit.com)
  • We also studied the role of, the local immune system of gastric mucosa in the pathogenesis of gastritis. (medscimonit.com)
  • Large amount of CD lymphocytes (CD 3+ CD 4+ CD 8+) and increased marker expression of CD 11a, CD 45 RO, HLA-DR and, to a lesser degree, CD 15 suggest immune system involvement in the pathogenesis of gastritis in children with collagenosis. (medscimonit.com)
  • Shh expression is reported-ly to be reduced in Helicobacter pylori-associated gastritis. (elsevierpure.com)
  • Adamsson J, Ottsjo LS, Lundin SB, Svennerholm AM, Raghavan S. Gastric expression of IL-17A and IFNγ in Helicobacter pylori infected individuals is related to symptoms. (medscape.com)
  • Here we demonstrated that an inflammasome molecule, absent in melanoma 2 (Aim2), was upregulated in patients with gastric cancer and in spasmolytic polypeptide-expressing metaplasia of chronically Helicobacter felis-infected stomachs in mice. (jci.org)
  • In recent studies, a unique seaweed extract showed promise for the treatment of Helicobacter pylori (H. pylori)-related diseases and gastric cancer, while palm tocotrienol complex demonstrated gastroprotective effects. (naturalproductsinsider.com)
  • A unique seaweed extract showed promise for the treatment of Helicobacter pylori (H. pylori)-related diseases and gastric cancer, according to new research undertaken at the University of Western Australia. (naturalproductsinsider.com)
  • In the present work, effects in the gastric mucosa of mice treated with Pteridium aquilinum were evaluated, as well as molecular mechanisms underlying the synergistic role with Helicobacter pylori infection. (pasteur.fr)
  • Infection with cagA positive H pylori induces greater gastric chemokine mRNA expression in the antral mucosa, which may be relevant to the increased mucosal damage associated with cagA positive H pylori infection. (bmj.com)
  • The aim of the present study is to evaluate the expression of tryptophan hydroxylase (TpH-1) in gastric mucosa of patients with symptomatic and asymptomatic H. pylori infection in relation to the intensity of bacterial colonization and severity of dyspeptic symptoms. (archivesofmedicalscience.com)
  • Conclusions: Suppressed Shh expression in the gastric mucosa by H. pylori infection was significantly restored following eradication of the infection. (elsevierpure.com)
  • METHODS: Cases of normal oesophageal squamous mucosa (11 fresh endoscopic biopsies and 10 formalin fixed, paraffin embedded tissue blocks), BM (11 biopsies and 11 tissue blocks), and normal gastric body mucosa (five biopsies and five tissue blocks) were analysed using reverse transcriptase PCR, Western blotting, and immunohistochemistry for EpCAM, and reverse transcriptase PCR for gpA33. (ox.ac.uk)
  • Scattered EpCAM expressing cells were found in the gland bases of normal gastric body mucosa. (ox.ac.uk)
  • Moreover, it leads to destructive changes in the gastric and duodenal mucosa and can be the cause of asymptomatic peptic ulcers [ 17 - 19 ]. (archivesofmedicalscience.com)
  • In the index case, the disorder is characterized by abundant deposition of hemosiderin in all tissues investigated (mesenteric lymph node, liver, gastric and duodenal mucosa, and also in squamous cell carcinoma of the lung). (intrinsiclifesciences.com)
  • RESULTS: mRNA expression of all five chemokines was significantly greater in H pylori positive than in H pylori negative mucosa. (bmj.com)
  • In H pylori positive patients, in the antrum C-X-C chemokine mRNA expression was significantly greater in cagA positive patients than in cagA negative patients, but there were no significant differences in C-C chemokine mRNA expression. (bmj.com)
  • In H pylori positive patients, chemokine mRNA expression in the corpus was less than in the antrum. (bmj.com)
  • In contrast to the antrum, only GRO alpha mRNA expression was significantly greater in cagA positive infection. (bmj.com)
  • Polymorphonuclear cell infiltration was correlated with C-X-C chemokine mRNA expression. (bmj.com)
  • Significant correlations were also found between bacterial density and C-X-C chemokine mRNA expression. (bmj.com)
  • The level of mRNA expression of tryptophan hydroxylase (TpH-1) was estimated in gastric mucosa with RT-PCR. (archivesofmedicalscience.com)
  • Ulceration induced the very rapid expression of first rSP and then rITF mRNA, whereas the mRNAs encoding EGF and TGF alpha increased at later times, with maxima recorded at 3 and 6 days, respectively. (nih.gov)
  • Hybridization in situ detected extensive rSP mRNA expression in the regenerative epithelia. (nih.gov)
  • Using endoscopic biopsies taken from the gastric antrum of 42 subjects infected with H. pylori and 42 uninfected subjects, mucosal CCL20 mRNA and protein levels were measured by real-time polymerase chain reaction and enzyme-linked immunosorbent assay, respectively. (nih.gov)
  • A ) RT-qPCR of Ifnb1 (IFN-β gene) mRNA expression in Aim2 -/- versus WT bone marrow-derived macrophages (BMDCs) transfected with metaplastic gastric DNA from 6-month H . felis -infected stomach, relative to untransfected controls. (jci.org)
  • B ) RT-qPCR of IFN-β gene mRNA expression in 6-month H . felis -infected Aim2 -/- versus WT stomachs, relative to uninfected controls. (jci.org)
  • D ) RT-qPCR analyses of gastric CD3 mRNA expression in 6-month H . felis -infected WT, Aim2 -/- , IFNAR1 -/- , and Aim2 -/- IFNAR1 -/- stomachs relative to uninfected controls. (jci.org)
  • Expression of the oestrogen regulated pNR-2 mRNA in human breast cancer: relation to oestrogen receptor mRNA levels and response to tamoxifen therapy. (xenbase.org)
  • RESULTS: Strong EpCAM mRNA expression was detected in all the BM cases, in contrast to weak expression in all the normal gastric mucosal samples and no expression in any of the normal oesophageal mucosal samples tested. (ox.ac.uk)
  • CONCLUSIONS: EpCAM protein and gpA33 mRNA expressions are specific and sensitive markers of BM. (ox.ac.uk)
  • In contrast, Aim2 deficiency led to an increase in gastric CD8+ T cell frequency, which exacerbated metaplasia. (jci.org)
  • Gastric cancer (GC) pathogenesis involves genetic, epigenetic and environmental factors. (oncotarget.com)
  • abstract = "Background/Aims: Sonic hedgehog (Shh) is a morphogen involved in many aspects of patterning of the gut during embryogenesis and in gastric fundic gland homeostasis in the adult. (elsevierpure.com)
  • To these aim, chromatin immunoprecipitation (ChIP) assays for the repressive trimethylation of histone 3 at lysine 9 (H3K9triMe) and its specific histone-lysine Nmethyltransferase (SUV39H1) were performed on biopsies of normal and tumor human gastric tissues. (unina.it)
  • In gastric mucosa from HD subjects, compared to control subject biopsies, a reduced expression of gastrin (a marker of G cells) was found. (cardiff.ac.uk)
  • Differential expression analysis of ileal, transverse colon, and rectal biopsies were supplemented by a comparison of transcriptomes from platelets and leukocytes subsets, including CD4+, CD8+, CD14+, CD15+, and CD19+ cells. (biomedcentral.com)
  • Loss of ARID1A expression occurred in the scales of several glands, which were morphologically characterized as authentic, pseudo-pyloric, or intestinal metaplastic glands devoid of dysplastic changes. (bvsalud.org)
  • The trefoil peptide intestinal trefoil factor (ITF) plays a critical role in the protection of colonic mucosa and is essential to restitution after epithelial damage. (embl.de)
  • The expression profiles of the intestinal mucosa have not been comprehensively investigated in asthma. (biomedcentral.com)
  • This suggests that airway mucosal pathology could co-occur with intestinal mucosa dysfunction. (biomedcentral.com)
  • CONCLUSIONS: The UACL has a unique profile of mucin gene expression. (embl.de)
  • GKN1 is down-regulated in gastric tumor tissues and derived cell lines so it has recently emerged as a potential biomarker for gastric cancer. (unina.it)
  • It has also been demonstrated that GKN1 expression induces apoptosis in gastric cancer cells thus suggesting a possible role of the protein as tumor suppressor. (unina.it)
  • The results showed that GKN1 downregulation in gastric cancer tissues is associated with high levels of H3K9triMe and with the recruitment of SUV39H1 on GKN1 promoter, suggesting the presence of an epigenetic transcriptional complex that negatively regulates GKN1 expression in gastric tumor. (unina.it)
  • It has been suggested that treatment with propofol serves a tumor‑suppressing role in human gastric cancer (GC). (spandidos-publications.com)
  • CONCLUSION: Our immunohistochemical studies might suggest that the gastrinoma-associated excessive progastrin tissue concentrations led to diminished expression of E-cadherin within the gastric mucosa and promoted tumor development of a signet-ring cell carcinoma. (tum.de)
  • We also studied RUNX3 expression by immunohistochemistry (IHC) in 40 samples, and validated differences in methylation levels between tumor, normal, and immune tissue in 14 additional samples. (oncotarget.com)
  • Gastric cancer is the fifth most common malignant tumor and the fourth leading cause of cancer-related death worldwide, after lung cancer, colorectal cancer, and liver cancer [ 1 ]. (hindawi.com)
  • Expression patterns of transforming growth factor-beta and its receptors in the gastric mucosa of patients with refractory gastric ulcer. (ntu.edu.tw)
  • Comparative antiulcer effect of bisdemethoxycurcumin and curcumin in a gastric ulcer model system. (wellnessresources.com)
  • The antiulcer effect of bisdemethoxycurcumin, a yellow pigment found mainly in rhizomes of Curcuma longa, was compared with curcumin in gastric ulcer model systems to validate its clinical application as a remedy for peptic ulcer. (wellnessresources.com)
  • twice daily for 10 days showed a significant curative efficacy in accelerating the healing of acetic acid-induced chronic gastric ulcer and promotion of mucosal regeneration in the ulcerated portion in a dose-related manner with potency equal to curcumin. (wellnessresources.com)
  • These results indicated that bisdemethoxycurcumin directly accelerates gastric ulcer healing with potency equal to curcumin. (wellnessresources.com)
  • Coordinated localisation of mucins and trefoil peptides in the ulcer associated cell lineage and the gastrointestinal mucosa. (embl.de)
  • To investigate the significance of ARID1A abnormalities in the early phase of cancer development in the stomach , we screened for ARID1A loss and p53 overexpression in glands in non-neoplastic gastric mucosa using immunohistochemistry . (bvsalud.org)
  • Immunohistochemistry and the in vitro infection assay showed that CCL20 was principally produced by the gastric epithelium. (nih.gov)
  • C ) Representative CD3 immunohistochemistry (brown) of WT, Aim2 -/- , IFNAR1 -/- , and Aim2 -/- IFNAR1 -/- 6-month H . felis -infected gastric mucosa. (jci.org)
  • METHODS: Expression of mucin genes in the UACL from small bowel tissue of patients with Crohn's disease was detected by in situ hybridisation, and localisation of the products by immunohistochemistry. (embl.de)
  • We therefore set out to study gastric mucosa of patients with HD, looking for abnormalities of mucosal cells using immunohistochemistry. (cardiff.ac.uk)
  • Immunohistochemistry showed strong EpCAM protein expression in BM and complete absence of expression in normal oesophageal squamous epithelium. (ox.ac.uk)
  • These findings indicate that epigenetic mechanisms leading to the inactivation of GKN1 play a key role in the multi-step process of gastric 2 carcinogenesis and would provide an essential starting point for the development of new therapeutic strategies based on epigenetic targets for alternatives gene. (unina.it)
  • The biological effects of exposure to this plant within the gastric carcinogenesis process are not fully understood. (pasteur.fr)
  • The gene transcription alterations and the induced glycophenotypic changes observed in the gastric mucosa contribute for the understanding of the molecular mechanisms underlying the role of Pteridium aquilinum in the gastric carcinogenesis process. (pasteur.fr)
  • Characterization of E-cadherin expression in normal mucosa, dysplasia and adenocarcinoma of gastric cardia and its influence on prognosis. (wjgnet.com)
  • Cases of endocervical adenocarcinoma (n = 90), adenocarcinoma in situ (AIS) (n = 32), benign glandular lesions (n = 36), and normal endocervical mucosa (n = 5) were selected from Stony Brook Medicine and the University of Massachusetts from 2002 to 2013. (medscape.com)
  • [ 15 ] Other studies have shown K17 to be a negative prognostic indicator in gastric adenocarcinoma, bladder carcinoma, epithelial ovarian carcinoma, and triple-negative breast carcinoma. (medscape.com)
  • Thus, the goal of this study was to determine if K17 expression is a negative prognostic biomarker associated with decreased survival of patients with endocervical adenocarcinoma. (medscape.com)
  • Strong pS2 gene expression was also observed in the normal gastric mucosa and in the regenerative tissues surrounding ulcerous lesions of the gastrointestinal tract . (xenbase.org)
  • Targeted deep sequencing of gastric marginal zone lymphoma identified alterations of TRAF3 and TNFAIP3 that were mutually exclusive for MALT1 rearrangement. (cdc.gov)
  • In asymptomatic infections eradication of H. pylori is a preventive management of gastric cancer, especially in patients with a family history of this disease [ 20 - 22 ]. (archivesofmedicalscience.com)
  • We tested 230 tissue blocks of 77 patients with gastric carcinoma , and in 10% of non-neoplastic mucosa we detected ARID1A-lost and in 3.7% p53-overexpressed foci. (bvsalud.org)
  • In early gastric cancer cases (n = 46), ARID1A-lost foci were frequent in samples of patients with Epstein-Barr virus -associated gastric carcinoma (p = 0.037). (bvsalud.org)
  • The validity of these measures was compared with Campylobacter-like organism analysis (gold standard) performed on patients requiring gastric biopsy. (who.int)
  • Patients and controls a possible cause of gastric ulcers seen in This was a case-control study of H. pylori patients with CLD [ 10,11 ]. (who.int)
  • Then, the relationship between the expression level of the core genes and the prognosis of gastric cancer patients was analyzed using the Gene Expression Profiling Interactive Analysis (GEPIA) database. (hindawi.com)
  • Due to the asymptomatic and insidious nature, gastric cancer is rarely diagnosed in its early stage in China, and most patients have already advanced disease stage by the time of diagnosis and have poor prognoses [ 8 - 10 ]. (hindawi.com)
  • Pathomorphological studies of gastrointestinal mucosa of asthma patients indicated increased activity of mucus-producing cells (as in the bronchi), barrier degeneration, and hyperplasia [ 10 ]. (biomedcentral.com)
  • Fewer than 5% of patients develop a complication, such as abdominal perforation, gastric outlet obstruction, or esophageal stricture. (medscape.com)
  • Our results showed that exposure to Pteridium aquilinum induces histomorphological modifications including increased expression of acidic glycoconjugates in the gastric mucosa. (pasteur.fr)
  • Shen XZ, Koo MW, Cho CH. Sleep deprivation increase the expression of inducible heat shock protein 70 in rat gastric mucosa. (wjgnet.com)
  • Western blot analysis in ulcerated gastric mucosa showed that bisdemethoxycurcumin dose-dependently reduced the increased protein expression level of iNOS but not TNF-alpha. (wellnessresources.com)
  • Gastrokine1 (GKN1) is a highly expressed stomach protein important for maintaining the physiological function of the gastric mucosa. (unina.it)
  • Mice homozygous for a knock-out allele or allele that produces a proteolytically inactive protein exhibit increased sensitivity to ethanol-induced gastric mucosa injury. (jax.org)
  • We show that the mouse putative pS2 protein sequence and the physiological pattern of expression of the mouse pS2 gene are well conserved. (xenbase.org)
  • Expression of the pNR-2/pS2 protein in diverse human epithelial tumours. (xenbase.org)
  • EGR-1 has also been found to regulate the expression of VAMP2 (a protein important for synaptic exocytosis ). (wikipedia.org)
  • Scope includes mutations and abnormal protein expression. (cancerindex.org)
  • RUNX3 showed protein silencing in cancer and normal mucosa, compared to inflammatory peritumoural infiltrate in almost all cases, showing a non-lymphocytic predominant pattern and being correlated with epigenetic silencing. (oncotarget.com)
  • Histamine and its receptors represent a complex system of immunoregulation with distinct effects mediated by four GPCRs (G protein-coupled receptors HRs 1-4) and their differential expression, which changes according to the stage of cell differentiation and microenvironmental influences. (hindawi.com)
  • Western blotting showed EpCAM protein expression in all the BM cases and in none of the normal gastric or oesophageal mucosal samples tested. (ox.ac.uk)
  • Using in situ hybridization, we show that although coexpressed in the fundus , the antrum and the antrum -pyloric regions of the stomach , the mouse pS2 and mSP genes exhibit distinct and complementary cellular patterns of expression. (xenbase.org)
  • In order to investigate possible histological differences related to gastric acid production, we evaluated the cell density of acid producing parietal cells, as well as gastrin producing cells (the endocrine cell controlling parietal cell function). (cardiff.ac.uk)
  • The symptoms of Zollinger-Ellison syndrome (ZES) are secondary to hypergastrinemia, which causes hypertrophy of the gastric mucosa, leading to increased numbers of parietal cells and increased maximal acid output. (medscape.com)
  • OBJECTIVE: In this study we investigated the histopathological and molecular findings in the gastrointestinal wall of a patient with multiple endocrine neoplasia type 1 with malignant duodenal gastrinoma and multiple gastric ECL cell tumors, who additionally developed a signet-ring cell carcinoma of the stomach. (tum.de)
  • Coordinated localisation of trefoil peptides and mucins in UACL and normal gastrointestinal epithelia suggests they may assist each others' functions in protection and repair of gastrointestinal mucosa. (embl.de)
  • We hypothesized that NSAID treatment would preserve muscle performance better than antibiotic treatment alone, by reducing infection-associated inflammation and by increasing expression of cytoprotective Hsp. (biomedcentral.com)
  • Its expression is upregulated on activated lymphocytes and endothelial cells. (bdbiosciences.com)
  • These gastric CD8+ T cells from Aim2-/- mice were found to have lost their homing receptor expression (sphingosine-1-phosphate receptor 1 [S1PR1] and CD62L), a feature of tissue-resident memory T cells. (jci.org)
  • The mouse pS2 gene is highly expressed in the stomach mucosa cells, whereas no pS2 gene expression could be detected in the mouse mammary gland, even during postnatal development processes dependent on growth factors or hormones. (xenbase.org)
  • Furthermore, reverse transcription‑quantitative PCR was used to examine the expression levels of circular RNA‑PVT1 (circ‑PVT1), micoRNA‑195‑5p (miR‑195‑5p) and ETS1 in GC tissues and cells. (spandidos-publications.com)
  • Propofol could inhibit Bcl‑2 and MMP9 expression, and increase P21 expression in GC cells. (spandidos-publications.com)
  • The expression levels of circ‑PVT1 and ETS1 were increased in GC tissues and cells, and miR‑195‑5p was decreased. (spandidos-publications.com)
  • Additionally, the treatment with propofol could lead to decreased circ‑PVT1 expression in GC cells. (spandidos-publications.com)
  • Previous studies have investigated the inhibitory effect of propofol on cancer cells in a variety of tumors, such as breast ( 2 ), lung ( 3 ) pancreatic ( 4 ), ovarian ( 5 ), hepatic ( 6 ) and gastric cancer (GC) ( 7 , 8 ). (spandidos-publications.com)
  • CONTEXT: Gastric neuroendocrine tumors are rare neoplasms that originate from gastric enterochromaffin-like (ECL) cells in the oxyntic mucosa. (tum.de)
  • RESULTS: Immunohistochemical studies of gastric ECL cell tumors showed a largely diminished E-cadherin expression in comparison to gastric surface mucosa cells and a loss of E-cadherin expression in the cells of the signet-ring carcinoma. (tum.de)
  • Expression is particularly high in the pancreas where it is thought to play a role in the differentiation of pancreatic beta cells. (embl.de)
  • CD15 (Lewis x), also known as stage specific embryonic antigen-1 (SSEA-1) is a trisacharide determinant (3-fucosyl-N-acetyllactosamine) expressed on several glycolipids, glycoproteins and proteoglycans of various cell types, e.g. granulocytes, mast cells, monocytes, macrophages, cells of gastric mucosa, nervous system or various tumour cells. (exbio.cz)
  • Cells with high surface expression of Le(x) antigen exhibit strong self-aggregation, based on calcium-dependent Le(x)-Le(x) interaction. (exbio.cz)
  • Benharroch D, Dima E, Levy A, Ohana-Malka O, Ariad S, Prinsloo I, Mejirovsky E, Sacks M, Gopas J: Differential expression of sialyl and non-sialyl-CD15 antigens on Hodgkin-Reed-Sternberg cells: significance in Hodgkin's disease. (exbio.cz)
  • Ileal mucosa in asthma exhibits a specific transcriptomic profile, which includes the overexpression of innate immune genes, mostly characteristic of Paneth and goblet cells, in addition to other changes that may resemble Crohn's disease. (biomedcentral.com)
  • Several studies have reported conflicting and inconclusive results concerning the clinical relevance of mucin expression in gastric carcinoma. (bmj.com)
  • This study investigated the correlations between aberrant expression of mucins in gastric carcinoma and patient clinicopathological features. (bmj.com)
  • The expression of MUC1, MUC2, MUC3, MUC5AC, and MUC6 was investigated immunohistochemically in gastric carcinoma (n = 46) in relation to patient clinicopathological features. (bmj.com)
  • Membrane bound mucins MUC1 and MUC3 appear to be associated with the development of gastric carcinoma. (bmj.com)
  • Gastric cancer (GC) is still one of the leading causes of cancer-related deaths worldwide and high mortality rate is mainly due to late-stage diagnosis. (unina.it)
  • The results demostrated that GKN1 3'UTR was a direct target of hsa-miR-544a and miR-1245b-3p and showed an increase of miR-544a expression in the gastric cancer cell lines after TSA treatment. (unina.it)
  • Development of gastric cancer is often preceded by chronic inflammation, but the immune cellular mechanisms underlying this process are unclear. (jci.org)
  • Levels of expression of breast epithelial mucin detected by monoclonal antibody BrE-3 in breast-cancer prognosis. (xenbase.org)
  • Strong association between c-myb and oestrogen-receptor expression in human breast cancer. (xenbase.org)
  • Gastric cancer (GC) has high incidence and mortality and is among the most common malignancies: in 2012 it was the second-leading cause of cancer-related deaths worldwide [ 1 ]. (oncotarget.com)
  • Gastric cancer is among the most common malignant tumors of the digestive system. (hindawi.com)
  • This study explored the molecular mechanisms and potential therapeutic targets for gastric cancer occurrence and progression using bioinformatics. (hindawi.com)
  • The gastric cancer microarray dataset was downloaded from the Gene Expression Omnibus (GEO) database. (hindawi.com)
  • This study identified new potential molecular targets closely related to gastric cancer occurrence and development via mining public data using bioinformatics analysis methods. (hindawi.com)
  • According to the statistics of 2020 Global Cancer, about 1.09 million new gastric cancer cases and 769,000 gastric cancer death cases occurred globally in 2020 [ 1 ]. (hindawi.com)
  • In China, gastric cancer is ranked third in incidence and mortality [ 2 ]. (hindawi.com)
  • Although the incidence of gastric cancer has steadily declined in many countries, a trend whereby more and more younger people are being diagnosed with gastric cancer has been observed and cannot be ignored [ 3 , 4 ]. (hindawi.com)
  • Current treatments for gastric cancer include multimodal treatment using a combination of surgery, chemotherapy, radiotherapy, and/or immunotherapy [ 5 - 7 ]. (hindawi.com)
  • Thus, the early detection and treatment of gastric cancer are crucial to improving treatment outcomes, and reducing its mortality rate is essential. (hindawi.com)
  • At present, gene chip technology has a vital role in diagnosing gastric cancer and evaluating related gene expression [ 13 ]. (hindawi.com)
  • In this study, a data mining strategy was used to obtain 2 microarray datasets of gastric cancer from the GEO database to identify differentially expressed genes (DEGs) associated with gastric cancer occurrence and progression. (hindawi.com)
  • Epidemiological studies have shown an association between bracken fern exposure and gastric cancer development in humans. (pasteur.fr)
  • Pharmacology of a new porcine pancreatic polypeptide with spasmolytic and gastric acid secretion inhibitory effects. (xenbase.org)
  • Mutations in the epithelial cadherin (E-cadherin) gene have been shown to be associated with the occurrence of diffuse gastric carcinomas in affected families. (tum.de)
  • showed a strong inhibitory effect on gastric acid secretion in pylorus-ligated rats whereas curcumin (5-20 mg/kg body wt. (wellnessresources.com)
  • 1, 2 Most studies of MUC1 expression in breast carcinomas have shown that increased membrane MUC1 mucin expression on the apical cell surface is associated with a better prognosis (reviewed in Rahn and colleagues 2 ), whereas circumferential staining in tumour cell cytoplasm is associated with a worse prognosis. (bmj.com)
  • The white arrows denote dysplastic gastric glands that have invaded the gastric submucosa. (jci.org)
  • These results disclose the molecular basis for the altered pattern of glycan structures observed in the mice gastric mucosa. (pasteur.fr)
  • Basal expression of Hsp27 in monocytes without heat challenge (WHC) was positively correlated with FR at baseline and significantly increased by treatment with piroxicam compared to placebo. (biomedcentral.com)
  • The mouse one P-domain ( pS2 ) and two P-domain ( mSP ) genes exhibit distinct patterns of expression. (xenbase.org)
  • The transcriptome analysis of gastric mucosa showed that upon exposure to Pteridium aquilinum several glycosyltransferase genes were differently expressed, including Galntl4, C1galt1 and St3gal2, that are mainly involved in the biosynthesis of simple mucin-type carbohydrate antigens. (pasteur.fr)
  • Curiously, the ageing process impairs expression or activity of HRs, and the enzymes HDC and DAO may contribute to the progression of allergic reactions and various neurodegenerative disorders [ 5 ]. (hindawi.com)
  • Aberrant (upregulated) expression of the MUC1 mucin has been seen in breast carcinomas and other neoplasms, such as colon and pancreatic cancers. (bmj.com)
  • A model of gastric ulceration in the rat has been used to determine the expression of four messenger RNAs (mRNAs) encoding peptides considered to play active parts in the healing response. (nih.gov)
  • Ulceration was caused under anaesthesia by brief application of a liquid nitrogen-filled cryoprobe to the gastric serosal surface and RNA expression was monitored over the next 10 days. (nih.gov)
  • Gastric ulceration: critical events at the neutrophil--endothelium interface. (medscape.com)
  • All normal gastric mucosa samples expressed MUC1, MUC5AC, and MUC6. (bmj.com)
  • Lost expression of AT-rich interaction domain 1A in the gastric mucosa-A constituent of field cancerization in the stomach. (bvsalud.org)
  • P-domain peptides expressed in Xenopus laevis stomach mucosa. (xenbase.org)
  • MUC2 and TFF3 were colocalised throughout the large and small bowel mucosa. (embl.de)
  • The results of the present study revealed that ketamine treatment induced NF‑κB p65 translocation to nuclei and activated COX‑2 expression and prostaglandin (PGE)2 production in bladder tissue, whereas COX‑2 inhibitor suppressed the inflammatory effect. (spandidos-publications.com)
  • Previous experimental observations revealed that KIC occurred in bladder mucosa and decreased bladder capacity, enhanced detrusor hyperactivity and thereafter induced interstitial fibrosis ( 1 ). (spandidos-publications.com)
  • Its antiulcer effect might be due to its properties of decreasing gastric acid secretion and enhancing the mucosal defensive mechanism through suppression of iNOS-mediated inflammation. (wellnessresources.com)
  • Effects of amphetamine on the AMPA-mediated synaptic activity and the expression of AMPA receptor subunit 2 of brain neurons. (ntu.edu.tw)