• CD15 (Lewis x), also known as stage specific embryonic antigen-1 (SSEA-1) is a trisacharide determinant (3-fucosyl-N-acetyllactosamine) expressed on several glycolipids, glycoproteins and proteoglycans of various cell types, e.g. granulocytes, mast cells, monocytes, macrophages, cells of gastric mucosa, nervous system or various tumour cells. (exbio.cz)
  • The stage-specific embryonic antigen 4 (SSEA4) is com- isolate the NSCs from neonatal mice and rats (Campos monly used as a cell surface marker to identify the pluri- et al. (lu.se)
  • The stage-specific embryonic antigen 4 (SSEA4) is brain. (lu.se)
  • Stage-Specific Embryonic Antigens" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (uams.edu)
  • This graph shows the total number of publications written about "Stage-Specific Embryonic Antigens" by people in UAMS Profiles by year, and whether "Stage-Specific Embryonic Antigens" was a major or minor topic of these publications. (uams.edu)
  • Below are the most recent publications written about "Stage-Specific Embryonic Antigens" by people in Profiles over the past ten years. (uams.edu)
  • Expression of the activation marker CD30 may be seen in occasional tumor cells. (webpathology.com)
  • Coexpression of CD15 and CD30 (usually associated with classical Hodgkin's lymphoma) may be seen in some PTCL, NOS. (webpathology.com)
  • Peripheral T-cell lymphoma with aberrant expression of CD30, CD15, and CD20. (cityofhope.org)
  • Overexpression of CD30 antigen in hematopoietic malignancies make the antigen clinically useful as a biological tumor marker. (lookformedical.com)
  • Efficacy was dependent on the number of CD8+ T cells able to recognize tumor antigens that infiltrated the malignant tissue. (unav.edu)
  • T cell-based immunotherapy, such as immune checkpoint blockade or adoptive T cell transfer, is limited by the ability of T cells to detect major histocompatibility complex (MHC)-presented antigen by tumor cells. (elifesciences.org)
  • Demonstration of tumor-specific antigens in human colonic carcinomata by immunological tolerance and absorption techniques. (wikidoc.org)
  • Using immunohistochemistry, we observed HOXD9 protein expression in human brain tumor tissues, including astrocytomas and glioblastomas. (123dok.net)
  • B-lymphocyte antigen CD20 or CD20 is an activated- glycosylated phosphoprotein expressed on the surface of all B-cells beginning at the pro-B phase ( CD45 R+, CD117 +) and progressively increasing in concentration until maturity. (wikidoc.org)
  • Antibody FMC7 ( F linder M edical C entre) appears to recognise a conformational variant of CD20 [10] [11] also known as the FMC7 antigen. (wikidoc.org)
  • A bivariate pseudocolor density plot showing the correlated expression of CD15 (or Ig Isotype control staining) versus side light-scatter signals (SSC-A) was derived from gated events with the forward and side light-scatter characteristics of intact human leucocytes. (bdbiosciences.com)
  • The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. (wikidoc.org)
  • 13 ] isolated mononuclear cells from human peripheral blood that were enriched for expression of the hematopoietic stem cell marker CD34 [ 13 ]. (hindawi.com)
  • Members of this nascent protein family are characterized by common structural features and similar intron / exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. (wikidoc.org)
  • While the neoplastic cells were negative, luminal staining of ductal structures was noted for CK7, CD15 and CEA in some of the microcystic adnexal carcinoma, desmoplastic trichoepithelioma and squamous cell carcinoma with ductal differentiation cases. (dadospdf.com)
  • About 30% to 40% of PTCL, NOS, express markers of cytotoxic T-cells such as T-cell intracellular antigen-1 (TIA-1). (webpathology.com)
  • CD133+), but are rarely codetected with the neural stem dents, very few human-specific NSC markers have been cell (NSC) marker CD15. (lu.se)
  • Populations positive for these markers were clearly observed in varying percentages in 30 different preparations (PDGFRand CD56 expression after two passages (totally, three passages). (phytid.org)
  • The antigens are useful markers in the identification of EMBRYONIC STEM CELLS. (uams.edu)
  • In glioma CSC (GCSC), the expression of some neural stem markers, such as SOX2 and Musa-shi-1, has been reported[6,7]. (123dok.net)
  • Cells with high surface expression of Le(x) antigen exhibit strong self-aggregation, based on calcium-dependent Le(x)-Le(x) interaction. (exbio.cz)
  • Benharroch D, Dima E, Levy A, Ohana-Malka O, Ariad S, Prinsloo I, Mejirovsky E, Sacks M, Gopas J: Differential expression of sialyl and non-sialyl-CD15 antigens on Hodgkin-Reed-Sternberg cells: significance in Hodgkin's disease. (exbio.cz)
  • A current research in contrast the activating impact that oxLDL and HSP60 have on T cells via DCs and irrespective of whether these two antigens depend upon each other for activation.112 DCs have been handled with human serum albumin (HSA) conjugated with malo. (dhfrinhibitor.com)
  • CD34 is expressed on early precursor cells of myeloid and B-cell lineages, and CD15 is expressed on immature monocytic lineage cells and highly expressed on granulocytic lineage cells.31 As diseased muscle contains many myeloid cells such as neutrophils, monocytes, and macrophages, a more specific marker for mesenchymal cells with adipogenic potential is AAF-CMK required for detailed characterization of these cells in human diseased muscle. (phytid.org)
  • d) Sorted CD56+ cells were reanalyzed for PDGFRand CD56 expression. (phytid.org)
  • Here, we demonstrate that NK cells (haNKs) engineered to express a PD-L1 chimeric antigen receptor (CAR) haNKs killed a panel of human and murine head and neck cancer cells at low effector-to-target ratios in a PD-L1-dependent fashion. (elifesciences.org)
  • Natural killer (NK) cell-based immunotherapy may overcome genetic mechanisms of resistance to T cell-based immunotherapy through antigen- and MHC-independent recognition of malignant cells. (elifesciences.org)
  • Here, we describe the pre-clinical in vitro and in vivo study of irradiated haNK cells engineered to express a second-generation chimeric antigen receptor (CAR) targeting programmed death-ligand 1 (PD-L1). (elifesciences.org)
  • Finally, we cultured human glioma cancer stem cells (GCSCs) from patient specimens found with high expression of HOXD9 in GCSCs compared with normal astrocyte cells and neural stem/progenitor cells (NSPCs). (123dok.net)
  • In melanocytic cells Glycophorin C gene expression may be regulated by MITF . (wikidoc.org)
  • Mouse monoclonal to CD15.DW3 reacts with CD15 (3-FAL ), a 220 kDa carbohydrate structure, also called X-hapten. (exposed-skin-care.net)
  • Transfection of mRNAs encoding the chimeric constructs achieved functional expression of the proteins able to act on their targets. (unav.edu)
  • Large amount of CD lymphocytes (CD 3+ CD 4+ CD 8+) and increased marker expression of CD 11a, CD 45 RO, HLA-DR and, to a lesser degree, CD 15 suggest immune system involvement in the pathogenesis of gastritis in children with collagenosis. (medscimonit.com)
  • Finally, we show that LIF increases the expression of the core transcription factors: Klf4, Fbx15, Nanog, Sox2 and c-Myc. (karger.com)
  • VC 2006 Wiley-Liss, Inc. a glycolipid antigen with globo-series carbohydrate core structures (Kannagi et al. (lu.se)
  • Multiparameter flow cytometric analysis of CD15 expression on human peripheral blood leucocyte populations. (bdbiosciences.com)
  • We report the case of a 12-year-old female patient with C1q deficiency presenting with intractable SLE who successfully underwent bone marrow transplantation from a human leukocyte antigen (HLA)-mismatched unrelated donor with an immunosuppressive conditioning regimen based on fludarabine, melphalan, and anti-thymocyte globulin. (bvsalud.org)
  • However, it has been difficult to obtain human mAbs, especially those directed at human antigens, for at least two reasons. (coek.info)
  • CD56 Expression Marks Human Group 2 Innate Lymphoid Cell Divergence from a Shared NK Cell and Group 3 Innate Lymphoid Cell Developmental Pathway. (smarttubeinc.com)
  • Results: In this study, we found high expression of the HOXD9 gene transcript in glioma cell lines and human glioma tissues by quantitative real-time PCR. (123dok.net)
  • CD15 is expressed on greater than 95% of granulocytes including neutrophils and eosinophils and to a varying degree on monodytes, but not on lymphocytes or basophils. (exposed-skin-care.net)
  • This goal is accomplished by tagging an antibody with a uniquely identifiable agent that is a surrogate for the level of expression of a given cellular constituent. (nature.com)
  • G-MDSC are also referred to as polymorphonuclear (PMN)-MDSC, which differ from conventional neutrophils via expression of lectin-type oxidized LDL receptor 1 (LOX-1), which inhibits T cell proliferation [ 7, 8 ]. (iospress.com)
  • The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. (wikidoc.org)
  • The protein has no known natural ligand [4] and its function is to enable optimal B-cell immune response, specifically against T-independent antigens. (wikidoc.org)
  • It catalyzes the synthesis of the non-sialylated antigen, Lewis x (CD15). (wikipedia.org)
  • CD15 antigen is important for direct carbohydrate-carbohydrate interaction and plays a role in mediating phagocytosis, bactericidal activity and chemotaxis. (exposed-skin-care.net)
  • Cell-surface molecules that exhibit lineage-restricted patterns of expression during EMBRYONIC DEVELOPMENT. (uams.edu)
  • CD10 expression is usually lacking in PTCL, NOS, except in the follicular variant. (webpathology.com)
  • of the major methods (label-free and isotope-labeling) to making protein expression measurements quantitative, especially in the context of profiling large numbers of proteins. (researchtoactionforum.org)
  • In 1972 a numerical system for the antigens in this blood group was introduced. (wikidoc.org)
  • Glycophorin A and glycophorin B carry the blood group MN and Ss antigens respectively. (wikidoc.org)
  • Glycosteroids used in the treatment of collagenosis partly reduced CD antigen expression in the gastric mucosa but did not affect HLA-DR antigen expression.The study was carried out within the framework of ST-60/AMG. (medscimonit.com)
  • Proteomics is the study of proteins on a large level, encompassing the many interests scientists and physicians have in their expression and physical properties. (researchtoactionforum.org)
  • CD3 subunits gamma, delta and epsilon are required for proper assembly, trafficking and surface expression of the TCR complex. (thermofisher.com)
  • We found no correlation between CD antigen expression and HLA-DR antigen expression and histopathological assessment of the mucosa. (medscimonit.com)
  • Aberrant T-Cell Antigen Expression in Classical Hodgkin Lymphoma is Associated with Decreased Event-Free Survival and Overall Survival. (cityofhope.org)
  • [1] The following year a new but related antigen was discovered in a Mrs Yus for whom an antigen in this system is also named. (wikidoc.org)
  • In the non erythroid cell lines, expression is lower than in the erythrocyte and the protein is differentially glycosylated . (wikidoc.org)
  • Plasmids Mammalian expression vectors pCLMSCVhyg-T7-Cdt1 pcDNA3.1-3HA-Cdt1 and pcDNA3.1-zeo-FLAG-ORC1 and bacterial expression vector pGEX-6P1-Cdt1 were described previously (5 12 The pEGFP-C1 expression vector was purchased from Clontech. (exposed-skin-care.net)