• Epilepsy is the most common chronic canine neurological syndrome and has serious implication on the quality of life (QoL) of both the dogs and owners ( 1 - 4 ). (frontiersin.org)
  • The long-term neurological function of the patients was determined using the Cerebral Performance Category scale. (physionet.org)
  • Up to two-thirds of patients can suffer persistent neurological deficits [ 3 , 4 ] and 20% may have post-stroke epilepsy and psychological distress [ 5 ]. (annchildneurol.org)
  • If untreated, TBM may have a poor outcome and permanent neurological sequelae, thus requiring rapid diagnosis and treatment. (medscape.com)
  • We assessed the relationship of brain oedema with acute seizure activity and long-term neurological outcome. (biomedcentral.com)
  • The outcomes variables were inpatient acute seizure activity and neurological disability at six-months post-discharge. (biomedcentral.com)
  • At six-month post-discharge, 21 (30.4%) had a poor neurological outcome. (biomedcentral.com)
  • When controlling for aetiology, increased volume of cerebral oedema was an independent risk factor for adverse neurological outcome at 6 months (OR 1.73 [1.06-2.83], p = 0.027). (biomedcentral.com)
  • An ability to establish the factors associated with acute seizures risk and poor neurological outcomes in patients with AES could support clinical care. (biomedcentral.com)
  • In addition, she sees patients with stroke and neurovascular diseases in her stroke clinic as well as patients discharged from the neurological ICU in the Outcomes clinic. (stanford.edu)
  • Her main interests are in brain hemorrhage, unusual and rare causes of stroke, cerebral venous thrombosis, anticoagulation management after strokes and use of technology for improving outcomes in the neurological ICU. (stanford.edu)
  • One of the most important features of contusions is their frequent enlargement in the hours following the injury, leading to potentially severe and life-threatening neurological deterioration in the absence of an early diagnosis, suggesting that timely recognition of trauma and confirmation of a brain contusion is detrimental in order to achieve a good long-term outcome [5] [6]. (symptoma.com)
  • patients with longer durations of posttraumatic amnesia have poorer outcomes. (medscape.com)
  • In their work, females had a significantly higher mortality and poorer outcome compared with males but this difference was no longer significant when covariables (presence of multiple injuries, postresuscitation pupil abnormalities, and Glasgow Coma Score) were controlled for. (hindawi.com)
  • University of Manchester scientists have discovered a persistent alteration in the immune system of patients, six months after they have been hospitalised for Covid-19, which could be associated with poorer health outcomes. (innovitaresearch.com)
  • Internationally she has given invited lectures in English and Spanish on a variety of pediatric epilepsy topics at regional education conferences organized by the American Epilepsy Society (AES), American Academy of Neurology and the International Child Neurology Society in locations as diverse as Ecuador, Paraguay, India and the Sudan. (icnapedia.org)
  • Perhaps most importantly, she has inspired many trainees to enter the fields of pediatric neurology and pediatric epilepsy and continues to mentor trainee from the undergraduate level through fellowship. (icnapedia.org)
  • Outcomes depend on resuscitation efforts and on the severity of global brain injury, which is comprised of primary insult (accrued during circulation standstill) and ongoing injury due to gaps between the energetic supply and demand from the brain (secondary brain injury). (biomedcentral.com)
  • Severe brain injury is the main determinant of poor outcome for patients surviving cardiac arrest resuscitation [1,2]. (physionet.org)
  • A multimodal approach to prognostication, including continuous electroencephalography (EEG) patterns, clinical assessment of initial illness severity, MR imaging, spontaneous and evoked potentials, and serum biomarkers, has been recommended. (ajnr.org)
  • Pre-Hospital assessment and determination of stroke severity is a new concept, with the best scale yet to be determined. (physio-pedia.com)
  • Although deficits have been reported to vary with injury severity, age at injury and sex, prognostication of outcome remains imperfect at a patient-specific level. (biomedcentral.com)
  • Regents of buy Building APIs with Node.js People was closed to disseminate a higher Injury Severity Construction, lower large Glasgow Coma Scale, lower neurotoxicologic world' soil at overpressure, greater potential information of diplopia and a as higher reaction for infected method benefit mines. (hotel-mainlust.de)
  • Her initial Glasgow Coma Scale score was 12. (medscape.com)
  • The Glasgow Coma Scale (GCS) is the mainstay for rapid neurologic assessment in acute head injury. (medscape.com)
  • Out of the nonruptured aneurysms, 7 (70%) were in 15 points of Glasgow Coma Scale and 1 patient (10%) was in 13 points. (surgicalneurologyint.com)
  • Before treatment, the clinical status was assessed using the Glasgow Coma Scale (GCS)[ 43 ] in patients with nonruptured aneurysms and the Hunt and Kosnik scale for ruptured. (surgicalneurologyint.com)
  • The primary measures of outcome were Glasgow Coma Scale at Discharge (GCSD) and disposition at discharge, and the secondary measures of outcome were AED modifications, Glasgow Outcomes Scale, and Modified-Rankin Scale. (medscimonit.com)
  • Controlling for age, admission Glasgow Coma Scale score, penetrating as compared to blunt injury, and presence of multiple trauma, females were 1.75 times more likely to die of their brain injury than males. (hindawi.com)
  • The management of patients with a head injury should be guided by clinical assessments and protocols based on the Glasgow Coma Scale and Glasgow Coma Scale Score. (ethiopianeurosurgery.com)
  • Great care should be taken when interpreting the Glasgow Coma Scale in the under fives and this should be done by those with experience in the management of the young child. (ethiopianeurosurgery.com)
  • A higher Glasgow coma scale (GCS) score on admission was a negative predictor of seizures (OR 0.61 [0.46-0.83], p = 0.001). (biomedcentral.com)
  • Glasgow coma scale pupil score (GCS-P) and the hospital mortality in severe traumatic brain injury: analysis of 1,066 Brazilian patients. (dana-farber.org)
  • Imaging studies and assessment of the Glasgow Coma Scale (GCS) are necessary to make the diagnosis. (symptoma.com)
  • 1 ), affecting immunocompromised patients by way year of diagnosis, and outcomes depend largely on of inhalation, with a risk of secondary dissemination. (cdc.gov)
  • Stroke is a major cause of death and disability, and patient outcomes depend on how quickly the blood flow can be restored to the damaged area of the brain. (physio-pedia.com)
  • The aim of this study was to compare acute outcome between men and women after sustaining a traumatic brain injury (TBI). (hindawi.com)
  • Outcomes measured included discharge destination and survival. (ajnr.org)
  • Outcome measures included the length of stay (LOS), the Extended Glasgow Outcome Scale (GOSE), the functional independence measure instrument (FIM), discharge destination, and mortality rate. (hindawi.com)
  • Some differences in primary outcome measures between the groups emerged on univariate analyses, but these differences were small and not significant after controlling for covariates. (medscimonit.com)
  • Herpes simplex virus encephalitis was associated with higher risk of poor outcomes in univariate analysis (OR 3.92 [1.08-14.20], p = 0.038). (biomedcentral.com)
  • Journal of Clinical Outcomes Management 2002;9:557-563. (cdc.gov)
  • Prospective data concerning SS and types of CCJM were evaluated in 89 patients between September 2002 and April 2014 using Bindal's scale. (surgicalneurologyint.com)
  • This study represented a cross-sectional evaluation of prospectively collected data conducted between September 2002 and April 2014 using Bindal's scale. (surgicalneurologyint.com)
  • Two patients (20%) had subarachnoid hemorrhage, 3 had epilepsy (30%), 3 (30%) had clinical signs of cranial nerve compression, and 4 (40%) had only headache. (surgicalneurologyint.com)
  • Two patients were in 1a grade of Hunt and Kosnik scale. (surgicalneurologyint.com)
  • At discharge, nine patients had 5 points of Glasgow Outcome Scale. (surgicalneurologyint.com)
  • According to Kamran grading scale, 9 patients (90%) were classified as Grade 4 and 1 patient (10%) as Grade 3. (surgicalneurologyint.com)
  • Our study has consecutive imaging assessment at least a year of follow-up in which aneurysm stable occlusion was observed in 90% of patients. (surgicalneurologyint.com)
  • It is not clear whether performing continuous EEG (cEEG) in critically ill patients during intensive care unit (ICU) treatment affects outcomes at discharge. (medscimonit.com)
  • We hypothesize that malignant EEG patterns are associated with greater extent of brain injury evident on MR imaging, which would explain the typically poor outcomes within this subset of patients. (ajnr.org)
  • Here, we have performed a prospective nationwide genetic association study using the Human Exome BeadChip and identified gene variants in encoding dynactin 4 ( DCTN4 ), retinoic acid early transcript 1E ( RAET1E ), and V-akt murine thymoma viral oncogene homolog 3 ( AKT3 ) to be associated with unfavourable outcome in patients with pneumococcal meningitis. (biomedcentral.com)
  • Here, we report our genome wide association study on the host side, analysing the associations between human genome variants and functional outcome in patients with pneumococcal meningitis using the Human Exome BeadChip. (biomedcentral.com)
  • Outcome was assessed in 23 patients via parent-rated questionnaires related to attention deficit hyperactivity disorder (ADHD) and executive functioning, using the Conners 3rd Edition Rating Scales (Conners-3) and Behaviour Rating Inventory of Executive Function (BRIEF) at a mean time since injury of 3.1 years. (biomedcentral.com)
  • These efforts are centered on improving surgery for patients with epilepsy and brain tumors, particularly those whose pathology is intimately involved with critical brain regions. (dana-farber.org)
  • Pre-hospital and Acute Stroke scales are standardized assessment tools are used to identify Stroke and clear a path to reperfusion. (physio-pedia.com)
  • A wide range of clinical assessment tools for selecting subjects with acute stroke has been developed in recent years. (physio-pedia.com)
  • Clinical and neuroimaging variables were analysed by multivariate logistic regression to assess for correlation with acute seizure activity and outcome. (biomedcentral.com)
  • This is a phase IIa, single-center, open-label, pilot clinical trial with blinded outcome assessment, of a single dose of vigabatrin in 12 consecutive PASE subjects. (biomedcentral.com)
  • Malignant electroencephalography patterns are considered predictive of poor outcome in comatose survivors of cardiac arrest. (ajnr.org)
  • however, the cardiac arrest literature is confounded by bias arising from a decreased likelihood in the provision of aggressive supportive care when poor outcomes are expected. (biomedcentral.com)
  • Furthermore, females were 1.57 times more likely to experience poor outcomes than males [ 5 ]. (hindawi.com)
  • A poor outcome was defined as a Glasgow outcome score (GOS) of 1-3. (biomedcentral.com)
  • Further studies assessing long-term outcomes are needed to better define the role of cEEG in this patient population. (medscimonit.com)
  • The objective of this proof of principle study was to evaluate a variety of patient variables, along with six brain-specific and inflammatory serum protein biomarkers, as predictors of long-term cognitive outcome following paediatric TBI. (biomedcentral.com)
  • The Cincinnati and Los Angeles scales have been validated in hospital trials, but studies are mixed when applied by EMS [2] . (physio-pedia.com)
  • Hospital mortality was 39.6% for females and 32.5% for males and the rates of unfavorable outcome were 58.7% for females and 53.4% for males [ 8 ]. (hindawi.com)
  • She then did a 2- year fellowship in Clinical Neurophysiology/Epilepsy at the Children's Hospital of Philadelphia. (icnapedia.org)
  • The samples included a community sample, and caregivers of children with Epileptic Encephalopathies (i.e., severe epilepsy), Muscular Dystrophy (MD) and Down Syndrome (DS). (springer.com)
  • 2. when the patient has clinical features that suggest that specialist neuroscience assessment, monitoring, or management are appropriate, irrespective of the result of any CT scan. (ethiopianeurosurgery.com)
  • Prognostication of survival and functional outcome in comatose survivors of cardiac arrest is challenging. (ajnr.org)
  • In addition to their importance for assessing the impact of therapeutic interventions in clinical trials, stroke scales are useful in the routine clinical setting as aids to improve diagnostic accuracy, help determine the appropriateness of specific treatments, monitor a patient's neurologic deficits through the continuum of care, and predict and gauge outcomes. (physio-pedia.com)
  • Measures included PROMIS-Fatigue SFs (7a, 8a, 4a), other PROMIS measures of RA symptoms, and selected patient reported outcomes including RAND-36 Vitality, Fatigue NRS, and patient global assessment of disease activity. (springer.com)
  • The primary outcome variable was CSA-AKI. (bvsalud.org)
  • The worst caregiver stress was reported by caregivers of children with epilepsy (M=63). (springer.com)
  • Physician asthma education program improves outcomes for children of low-income families. (cdc.gov)
  • Introduction: during the second wave of the COVID-19 pandemic in Mozambique, there was a surge in pediatric hospitalizations at a time when there was relatively little evidence, but significant concern about clinical outcomes in African children, particularly in higher-risk infants requiring, and health system capacity to respond. (bvsalud.org)
  • Performing cEEG did not improve discharge outcome but it significantly influenced AED prescription patterns. (medscimonit.com)
  • Nonparametric tests were performed to assess the relationship of patient outcome, MR imaging, and electroencephalography patterns. (ajnr.org)
  • Subjects with malignant electroencephalography patterns, invariably associated with bad outcomes, were observed to have whole-brain apparent diffusion coefficient measures similar to those in subjects with nonmalignant electroencephalography patterns and good outcome and different from those in subjects with nonmalignant electroencephalography patterns and bad outcomes. (ajnr.org)
  • ecological impact assessments should incorporate evaluation of impacts on animal movement patterns and should be undertaken for all large-scale fencing interventions. (cambridge.org)
  • We used the Grading of Recommendations Assessment, Development, and Evaluation to assess the quality of evidence. (bvsalud.org)
  • Epilepsy in dogs is a common chronic and serious disorder and may have an impact on the quality of life of the owners as well as the dogs themselves. (frontiersin.org)
  • The aim of this pilot study was to investigate the QoL score of dogs suffering from idiopathic epilepsy and their owners and if possible, investigate whether a breed specific difference exists. (frontiersin.org)
  • In conclusion, this study reports breed specific quality of life scores of dogs with epilepsy and their owners, and underlines that breed by itself, is also an important factor when managing epilepsy in dogs. (frontiersin.org)
  • Becker A, Watson W, Ferguson A, Dimich-Ward H, Chan-Yeung M. The Canadian asthma primary prevention study: outcomes at 2 years of age. (cdc.gov)
  • Higher levels of neuron specific enolase (NSE) and lower levels of soluble neuron cell adhesion molecule (sNCAM) were associated with higher scores on the inattention, hyperactivity/impulsivity and executive functioning scales of the Conners-3, as well as working memory and initiate scales of the MI from the BRIEF. (biomedcentral.com)
  • Higher levels of NSE only were associated with higher scores on the inhibit scale of the BRI. (biomedcentral.com)
  • Not only are different types of scales needed for these different purposes, but no single scale is suitable for capturing all of the effects of stroke. (physio-pedia.com)
  • Such studies should be performed prospectively, using a clear definition of cases with microbiological confirmation, and validated outcome scales [ 18 ]. (biomedcentral.com)
  • Using the Surgical Risk Preoperative Assessment System to Define the 'High Risk' Surgical Patient. (cuanschutz.edu)
  • Clinical outcomes from the observational cohort included swollen and tender joint counts (28), physician global assessment, and the RA Clinical Disease Activity Index (CDAI). (springer.com)
  • The assessment of a stroke patient involves stabilizing the Airway, Breathing, and Circulation (ABC). (physio-pedia.com)
  • Hence, several studies have been published investigating the effect of both epilepsy and ASM treatment on the QoL of dogs and their owner ( 1 , 4 , 26 , 27 ). (frontiersin.org)
  • Barnett TE, Fatis M, Sonnek D, Torvinen J. Treatment satisfaction with an asthma management program - a "five" year retrospective assessment. (cdc.gov)
  • Caregivers responded to PROMIS-29 and the University of Washington Caregiver Stress Scale (UW-CSS), a self-reported IRT-based item bank. (springer.com)
  • In 2006, I was awarded a scholarship from the College of Pharmacy, Kuwait University, to continue my postgraduate studies, and I gained an MSc in clinical pharmacy and a PhD in pharmaceutical care from the University of Strathclyde, Glasgow. (fip.org)
  • The University of Glasgow uses cookies for analytics. (gla.ac.uk)
  • and MINCEP Comprehensive Epilepsy Center (T.S.W.), University of Minnesota, Minneapolis. (neurology.org)
  • She founded the Pediatric Epilepsy Fellowship at the University of Texas at Austin and has garnered several teaching awards throughout her career. (icnapedia.org)
  • Time is Brain' i.e we should not waste any time at all in assessment. (physio-pedia.com)
  • Further prehospital research is required to improve the diagnostic utility of clinical assessments with the possible application of a two-step clinical assessment or involvement of simple brain imaging, such as transcranial ultrasonography. (physio-pedia.com)
  • Health Technology Assessment 27, article number: 9. (cardiff.ac.uk)
  • Akerman MJ, Sinert R. A successful effort to improve asthma care outcome in an inner-city emergency department. (cdc.gov)
  • Descriptive statistics with rates and proportions will be obtained regarding feasibility outcomes, along with the noncompartmental method for pharmacokinetic analyses. (biomedcentral.com)
  • Partial least squares (PLS) analyses were performed to identify factors measured at the time of injury that were most closely associated with outcome on (1) the Conners-3 and (2) the Behavioural Regulation Index (BRI) and (3) Metacognition Index (MI) of the BRIEF. (biomedcentral.com)
  • For all scales, the general population score is 50. (springer.com)
  • Thus, our results show that AKT3 influences outcome of pneumococcal meningitis. (biomedcentral.com)
  • The RACE Scale has had some positive results when tested among paramedics in Spain with more studies underway [3] , currently it is being adopted by many EMS Systems in the United States. (physio-pedia.com)
  • There is no standardized measure for its assessment nor data concerning the performance of PROMIS-Fatigue short forms (SFs) in people with RA. (springer.com)
  • But there is also growing interest into the impact of epilepsy and the use of anti-seizure medication (ASM) on owners and their dogs. (frontiersin.org)
  • You can read more in the PEER Forum equality and inclusion impact assessment . (ukri.org)
  • After serving in academic leadership positions in epilepsy for 10 years, she chose to combat health disparities directly by setting up the first pediatric epilepsy practice in El Paso, Texas, a city of 850,000 with only a single pediatric neurologist. (icnapedia.org)
  • She is active in health disparities research and founded and leads the Health Equity Committee through the Pediatric Epilepsy Research Consortium. (icnapedia.org)
  • Health has a role in considering key public health policy issues such as alcohol, where a coordinated approach is essential to achieving shared and interdependent outcomes. (who.int)
  • There is a clear breed predisposition in hunting dogs, shepherds and molosser dogs ( 9 , 10 ), and several recent studies focussed on the genetics of epilepsy ( 11 - 16 ). (frontiersin.org)
  • Whole-genome association studies, using an unbiased approach, may identify new candidate genes and pathophysiological mechanisms leading to an unfavourable outcome in pneumococcal meningitis [ 17 ]. (biomedcentral.com)
  • Regional hippocampal or basal ganglia injury was associated with a bad outcome regardless of electroencephalography findings. (ajnr.org)
  • An international team today reports the findings of an independent assessment of five commercially available assays for tumour DNA sequencing - a fast, cheap and less invasive method to diagnose and monitor cancer. (innovitaresearch.com)