• Endocardial fibroelastosis (EFE) refers to a pronounced, diffuse thickening of the ventricular endocardium and presents as unexplained heart failure in infants and children. (medscape.com)
  • Although the endocardium is thickened, the ventricular wall (myocardium) thickness is within the reference range. (medscape.com)
  • In this paper we present a means of visually representing information associated with the state and functionality of the myocardium in the left ventricular chamber of the heart. (actapress.com)
  • The vascular territories of the left ventricular myocardium are divided into 17 segments and illustrated by the cardiac segmentation model of the American Heart Association (AHA) 6,7 . (radiopaedia.org)
  • The myocardium is the muscle tissue comprising most of the heart. (petwellbeing.com)
  • The walls of the heart are largely made from myocardium, which is a special kind of muscle tissue. (daviddarling.info)
  • One of the most common, and perhaps the most damaging forms of tissue injury in the setting of revascularized acute MI is intramyocardial hemorrhage-a condition leading to bleeding within the heart muscle (myocardium). (nature.com)
  • The underlying pathophysiology of endocardial fibroelastosis (EFE) is believed to be deposition of acellular fibrocartilagenous tissue in the subendothelial layer of the endocardium predominantly involving the inflow tracts, apices of either left or both ventricles. (medscape.com)
  • The inner border merges with the subendocardial tissue layer, which contains collagen, elastic fibers small blood vessels and nerves as well as the Purkinje fibers and connects the extracellular matrix of the myocardium to the endocardium 4 . (radiopaedia.org)
  • Observations that favor a viral etiology include a clinical presentation similar to that of chronic myocarditis, findings of myocarditis or myocardial fibrosis in affected patients, a higher incidence following epidemics of coxsackievirus B infection, demonstration of persistent viral infection with molecular studies, and experimental production of the disease in animal models by viral infections of the myocardium. (medscape.com)
  • The myocardial failure may represent the end stage of various possible insults to the myocardium, including viral or immune-mediated inflammation, toxins or myocardial failure secondary to infarction. (vin.com)
  • More recently it has been also used for the evaluation of myocardial strain or simplified for the assessment of regional deformations of the myocardium such as thickening, shortening or lengthening. (radiopaedia.org)
  • The myocardium consists of cardiomyocytes grouped in strands also known as myofibres and the surrounding extracellular matrix with endomysial and perimysial components. (radiopaedia.org)
  • The myocardium consists of cardiac muscle , a type of muscle unlike any other muscle in the body. (wise-geek.com)
  • The endocardial thickening is believed to be caused by persistent and increased wall tension in the ventricles, possibly secondary to damaged myocardium, mitral regurgitation, or both. (medscape.com)
  • The compact portion of the atrioventricular (AV) node is a superficial structure located just beneath the RA endocardium, anterior to the ostium of the coronary sinus, and directly above the insertion of the septal leaflet of the tricuspid valve. (medscape.com)
  • The endocardium is a thin layer of epithelial cells , similar to that which lines the inside of blood vessels . (wise-geek.com)
  • The contractions of the myocardium are responsible for pumping oxygenated blood throughout the body, providing the body with the oxygen and other nutrients it needs to function properly. (wise-geek.com)
  • This form of cardiomyopathy is characterised by varying degrees of focal or diffuse fibrosis of the myocardium, sub-endocardium and endocardium. (vin.com)
  • Venous drainage of the myocardium is provided via the cardiac veins and the coronary sinus as well as the Thebesian veins 8 . (radiopaedia.org)
  • Here we show, using large animal models of reperfused MI, that intramyocardial hemorrhage - the most damaging form of reperfusion injury (evident in nearly 40% of reperfused ST-elevation MI patients) - drives delayed infarct healing and is centrally responsible for continuous fatty degeneration of the infarcted myocardium contributing to adverse remodeling of the heart. (nature.com)
  • Differences in thickness of the heart chamber walls are due to variations in the amount of myocardium present, which reflects the amount of force each chamber is required to generate. (daviddarling.info)
  • A subvalvular apparatus, comprising of 2 papillary muscles (anterolateral and posteromedial), arise from the LV myocardium and the chordae tendineae, supporting the leaflets. (nih.gov)
  • On the inside this muscle is provided with a lining of flat cells called the endocardium, which is direct contact with the blood within the heart. (daviddarling.info)
  • The flow of blood through the heart is controlled by the opening and closing of valves and the contraction and relaxation of the myocardium. (health.am)
  • Specifically, these altered forces are sensed by the endocardium through the mechanosensitive channel Trpv4 to control Klf2a transcription factor expression. (elifesciences.org)
  • Migration of Nkx2-5 -en + cells from outside the cardiac crescent towards the heart tube. (elifesciences.org)
  • While skeletal muscle fibers are arranged into regular, non-branching bundles, the muscle fibers of the myocardium branch at irregular angles, and connect to other muscle cells at junctions called intercalated discs. (wise-geek.com)