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Pleural NeoplasmsPleural EffusionPericardial EffusionPleural Effusion, MalignantOtitis Media with EffusionExudates and TransudatesTuberculosis, PleuralLymphoma, Primary EffusionNeoplasmsPancreatic NeoplasmsPericardiocentesisCardiac TamponadePleuraNeoplasms, Cystic, Mucinous, and SerousEmpyema, PleuralSubdural EffusionPleurodesisLung NeoplasmsAscitic FluidPleural CavityDrainageSkin NeoplasmsHydrothoraxMiddle Ear VentilationParacentesisPericarditisNeoplasms, Multiple PrimaryChylothoraxHerpesvirus 8, HumanKidney NeoplasmsMesotheliomaAscitesNeoplasms, Second PrimaryTalcAdenocarcinoma, MucinousOvarian NeoplasmsPleural DiseasesPleurisyPericardiectomyThyroid NeoplasmsMyeloproliferative DisordersDNA, NeoplasmEmpyemaThoracoscopyPericarditis, TuberculousHeart NeoplasmsLymphomaImmunohistochemistryLiver NeoplasmsPericardial Window TechniquesTomography, X-Ray ComputedTumor Markers, BiologicalParotid NeoplasmsCystadenomaNeoplasms, Connective and Soft TissueNeoplasms, Plasma CellAppendiceal NeoplasmsRetrospective StudiesRadiography, ThoracicThoracostomyCystadenoma, MucinousGastrointestinal NeoplasmsNeoplasms, ExperimentalEndocrine Gland NeoplasmsNeoplasm StagingAntigens, NeoplasmFatal OutcomeAdenocarcinomaCarcinoma, Pancreatic DuctalChest TubesCystadenoma, SerousEar, MiddleNeoplasms, Vascular TissueAcoustic Impedance TestsNeoplasm ProteinsEye NeoplasmsNose NeoplasmsSalivary Gland NeoplasmsChyleNeoplasms, Radiation-InducedSarcoma, KaposiAdenocarcinoma, PapillaryCarcinoma, PapillarySensitivity and SpecificityTesticular NeoplasmsNeoplasms, Muscle TissueNeoplasms, Glandular and EpithelialTreatment OutcomeCystadenocarcinoma, MucinousPicibanilAdenomaBone NeoplasmsSoft Tissue NeoplasmsHematologic NeoplasmsMediastinal NeoplasmsUterine NeoplasmsIntestinal NeoplasmsNeoplasms, Adnexal and Skin AppendageHemangiosarcomaVascular Neoplasms

Treatment of malignant pleuralDiagnosisEtiologyPulmonaryThoracicLeft pleural effusionRight pleural effusionBiopsyPericardialMetastaticAscitesLung CancerPeritoneal effusionsMalignancyExudativeNodulesCytologyRenalTumorCytologicalPrimaryBiopsiesPatientsAsbestosChestAdenocarcinomaMicroRNAsNeoplastic cellsChemotherapyMalignant cellsCancerDiseasesCAVITYOvarian

Treatment of malignant pleural1

• BLENOXANE has also been shown to be useful in the management of: Malignant Pleural Effusion BLENOXANE is effective as a sclerosing agent for the treatment of malignant pleural effusion and prevention of recurrent pleural effusions. (cancermonthly.com)

Diagnosis15

• Diagnosis and management of pleural effusions: a practical approach. (medscape.com)
• The differential diagnosis of pleural effusions. (medscape.com)
• Diagnosis and management of malignant pleural effusions. (medscape.com)
• Patients with pleural effusion at the initial diagnosis of lung adenocarcinoma usually indicate poor prognosis. (nih.gov)
• The clinical characteristics and prognostic factors of patients with EGFR mutated lung adenocarcinoma of different molecular subtypes combined with pleural effusion at initial diagnosis are still unclear. (nih.gov)
• We aimed to demonstrate the feasibility of non-invasive enumeration and immunophenotyping of EpCAM-positive cells in pleural fluid samples for the diagnosis of a MPE in NSCLC patients.Pleural fluid specimens were prospectively collected from patients with NSCLC and the CellSearch® technology was utilized for the enumeration of pleural EpCAM-positive cells (PECs) and determination of PD-L1 expression on PECs from pleural fluid samples. (nih.gov)
• 1. The cytologic diagnosis of malignant neoplasms in pleural and peritoneal effusions. (nih.gov)
• 2. The interval between the diagnosis of malignancy and the development of effusions, with reference to the role of cytologic diagnosis. (nih.gov)
• 14. Usefulness of chromosome examination in the diagnosis of malignant pleural effusions. (nih.gov)
• 20. [Cytological exam of the pleural fluid in the diagnosis of neoplastic pleuritis. (nih.gov)
• Review of recurrent pleural effusion and exophytic tumour at the sites of CTTD resulted in late diagnosis of MPE. (bvsalud.org)
• Additionally, pleural metastasis of breast cancer, which often presents as a malignant pleural effusion, typically occurs during the first few years after diagnosis but is not common after a long period of disease-free survival. (hcahealthcare.com)
• Downregulated microRNAs in the differential diagnosis of malignant pleural mesothelioma. (cdc.gov)
• Malignant pleural mesothelioma (MPM) is a rapidly fatal disease whose diagnosis, particularly through less invasive techniques such as analysis of pleural effusion, can be challenging. (cdc.gov)
• A repeat thoracentesis, along with a pleural biopsy on August 23, 2004, returned a diagnosis of epithelial mesothelioma. (worthingtoncaron.com)

Etiology1

• The most common etiology is asbestos exposure, but there are some reports without known asbestos exposure and other factors leading to malignant pleural mesothelioma (MPM). (asbestos-mesothelioma.com)

Pulmonary2

• The pulmonary specialist indicated that a number of the atypical cells identified were highly suspicious for an epithelial neoplasm, or cancer. (worthingtoncaron.com)
• Pulmonary manifestations in MM have been reported, but pleural effusion is infrequently seen. (ispub.com)

Thoracic1

• Malignant pleural effusion from various neoplasms constitutes the commonest thoracic malignancy in our tertiary hospital. (bvsalud.org)

Left pleural effusion2

• His chest radiograph showed left pleural effusion. (bvsalud.org)
• Chest X-ray revealed left pleural effusion and abnormal shadow in the right lung field. (mesothelioma-line.com)

Right pleural effusion3

• u003c/p\u003e","gb":"\u003cp\u003eLarge right pleural effusion. (radiopaedia.org)
• Large right pleural effusion. (radiopaedia.org)
• The chest X-ray revealed right pleural effusion, and chest computed tomography showed multiple large tumors from the diaphragm side with pleural effusion. (or.jp)

Biopsy7

• In only 7.1% of the 281 patients with malignant pleural effusions did biopsy reveal malignant disease when the results of cytologic study were negative for malignant disease. (nih.gov)
• Nearly half of the patients with lymphoma had lymphocytosis of the pleural fluid, but neither this finding nor the lymphocytic pleuritis noted on biopsy was diagnostic of lymphomatous involvement of the pleura. (nih.gov)
• In the patients with nonmalignant diseases, with the exception of six with tuberculous pleurisy, pleural biopsy was nondiagnostic even though the causes of pleural effusion were apparent from the clinical features. (nih.gov)
• This study shows that cytologic analysis has a higher sensitivity (P less than 0.001) than needle biopsy for diagnosing malignant pleural effusions. (nih.gov)
• The value of needle biopsy is limited in establishing the cause of pleural effusion that results from either malignant or nonmalignant disease, with the exception of tuberculous pleurisy. (nih.gov)
• Histological examination and culture of pleural biopsy were the most useful diagnostic workup for tuberculosis effusions, whereas repeated cytological examination of pleural fluid and pleural biopsy were most useful for malignant effusions. (who.int)
• Postoperatively pleural biopsy was performed by using thoracoscopy. (mesothelioma-line.com)

Pericardial3

• 5. Cytology of fluids from pleural, peritoneal and pericardial cavities in children. (nih.gov)
• 16. Malignancies in Pleural, Peritoneal, and Pericardial Effusions. (nih.gov)
• The most common sites of involvement are the pleural, pericardial, and peritoneal cavities. (nih.gov)

Metastatic2

• 10. Local immunotherapy with interferon-alpha in metastatic pleural and peritoneal effusions: correlation with immunologic parameters. (nih.gov)
• Findings suggestive of primary malignant left Ovarian neoplasm with diffuse omentoperitoneal spread of disease, metastatic omental deposits and metastatic abdominal nodes with malignant ascites. (cancer.org)

Ascites1

• Large neoplasms of greater than 10cm are often associated with pleural effusion and ascites (Meig syndrome triad). (cdc.gov)

Lung Cancer3

• Measurement and immunophenotyping of pleural fluid EpCAM-positive cells and clusters for the management of non-small cell lung cancer patients. (nih.gov)
• A malignant pleural effusion (MPE) is a common complication in non-small cell lung cancer (NSCLC) with important staging and prognostic information. (nih.gov)
• Despite a rising global incidence, long-term data reveal the U.S. [ incidence rate of pleural mesothelioma ] has decreased and overall survival for patients with mesothelioma is improving, according to a study presented at the annual meeting of the European Lung Cancer Congress, held from March 29 to April 1 in Copenhagen, Denmark. (asbestos-mesothelioma.com)

Peritoneal effusions2

• 11. The metabolic behaviour of the cellular populations in the pleural or peritoneal effusions from patients with malignant diseases. (nih.gov)
• 15. Tumor type and single-cell/mesothelial-like cell pattern of breast carcinoma metastases in pleural and peritoneal effusions. (nih.gov)

Malignancy2

• 3. Positive effusion cytology as the initial presentation of malignancy. (nih.gov)
• 6. Survival of patients with malignancy-associated effusions. (nih.gov)

Exudative2

• His pleural effusion analysis was consistent with exudative pleural effusion. (bvsalud.org)
• She was found to have pleural effusion which on further work up was exudative with predominant eosinophilia. (ispub.com)

Nodules1

• Chest computed tomography (CT) showed multiple enhanced nodules in the right pleural cavity. (mesothelioma-line.com)

Cytology3

• 8. The diagnostic yield of pleural fluid cytology in malignant pleural effusions. (nih.gov)
• Pleural fluid cytology did not yield malignant cells. (bvsalud.org)
• The data obtained were demography, aetiology, total number of pleural fluid specimens for cytology and pleural biopsies submitted for histology, pleurodesis and other treatment modalities. (bvsalud.org)

Renal1

• However, renal cell carcinoma with malignant pleural mesothelioma is very rare and this is the 2nd case in the Japanese literature. (mesothelioma-line.com)

Tumor3

• pleural fluid provides direct access for the analysis of these EV-miRNAs as biomarkers and potential targets and may provide insight into the underlying pathogenesis of tumor progression. (ox.ac.uk)
• A rare neoplasm of large B-cells usually presenting as serious effusions without detectable tumor masses. (nih.gov)
• In a study published recently in the journal Clinical Cancer Research, researchers at Baylor College of Medicine found that treating patients who have resectable malignant pleural mesothelioma, meaning that their tumor can be removed with surgery, with immunotherapy ahead of surgery resulted in favorable clinical outcomes. (asbestos-mesothelioma.com)

Cytological1

• Patients with MPEs are often candidates for advanced therapies, however, the current gold standard, cytological analysis of pleural fluid samples, has limited sensitivity. (nih.gov)

Primary4

• If Pleural effusion presence means we have to code primary malignant site followed by J91.0. (aapc.com)
• Synovial sarcoma occurs most commonly as primary neoplasm of the extremities. (or.jp)
• A chest film, taken by his primary care physician, revealed a large right-sided pleural effusion. (worthingtoncaron.com)
• Primary and secondary neoplasms of the liver, lungs, kidneys. (meditalia.net)

Biopsies1

• We retrospectively studied the results from thoracenteses and needle biopsies of the pleura performed in 414 patients with pleural effusions between 1973 and 1982. (nih.gov)

Patients8

• Predicting survival in patients with recurrent symptomatic malignant pleural effusions: an assessment of the prognostic values of physiologic, morphologic, and quality of life measures of extent of disease. (medscape.com)
• Malignant pleural effusion is one of the common clinical manifestations of patients with lung adenocarcinoma. (nih.gov)
• La présente étude prospective hospitalière portait sur tous les patients adultes (âgés de plus de 15 ans) atteints d'un épanchement pleural et admis dans des hôpitaux de recours pendant un an. (who.int)
• Driver mutations of young lung adenocarcinoma patients with malignant pleural effusion. (cdc.gov)
• Background: In the West African sub-region, significant morbidity and mortality are known to affect patients with malignant pleural effusion (MPE) but are highly under reported unlike USA, Europe or South Africa. (bvsalud.org)
• Background: Malignant pleural effusion (MPE) complicates many neoplasms and its incidence is expected to rise in parallel with the aging population and longer survival of cancer patients. (unimi.it)
• Conclusions: For the cohort of patients still needing indwelling pleural catheters (PC) after thoracoscopic talc poudrage, PleurX® is suggested when drain removal is unlikely due to short life expectancy or the high chance of pleurodesis failure. (unimi.it)
• Merck and the Canadian Cancer Trials Group (CCTG) have reported positive data from the Phase II/III CCTG IND.227/KEYNOTE-483 trial of Keytruda, along with chemotherapy, as first-line treatment for advanced malignant pleural mesothelioma patients. (asbestos-mesothelioma.com)

Asbestos1

• Malignant mesothelioma is a devastating neoplasm with a strong etiological relationship with asbestos exposure. (mesothelioma-line.com)

Chest2

• On August 17, 2004, after being referred to a pulmonologist, he underwent a right chest thoracentesis where two liters of blood-tinged fluid was drained from the space between the lung and the pleural lining. (worthingtoncaron.com)
• Chest X ray showed bibasilar infiltrates with bilateral pleural effusion. (ispub.com)

Adenocarcinoma2

• 13. The distinction of mesothelioma from adenocarcinoma in malignant effusions by electron microscopy. (nih.gov)
• Un estudio en Perú identificó el efecto anticancerígeno de la Annona muricata (AM), planta medicinal conocida como guanábana, en adenocarcinoma gástrico de ratón C-678 con resultados favorables, sin embargo, no se ha encontrado evidencia previa en células humanas. (bvsalud.org)

MicroRNAs1

• Extracellular Vesicles (EVs) and their contents, including microRNAs (miRNAs), can be isolated from all bodily fluids, including pleural fluid. (ox.ac.uk)

Neoplastic cells2

• 12. An immunoperoxidase study of S-100 protein in neoplastic cells in serous effusions. (nih.gov)
• Angiosarcoma is a malignant mesenchymal neoplasm in which the neoplastic cells demonstrate endothelial differentiation. (manipal.edu)

Chemotherapy2

• After 1 month of chemotherapy, he developed pleural effusion and died. (manipal.edu)
• Dr. Vallieres suggested a multi-modality regimen which included induction chemotherapy, a right-sided extra-pleural pneumonectomy (EPP) and adjuvant radiation treatments. (worthingtoncaron.com)

Malignant cells1

• Malignant pleural effusions often contain actual malignant cells. (nih.gov)

Cancer2

• Lung and breast cancer are the two most common causes of malignant pleural effusion (MPE). (ox.ac.uk)
• This is a case of breast cancer relapse after 7 years of disease-free survival with lung metastasis and malignant pleural effusion secondary to pleural metastasis and without locoregional recurrence. (hcahealthcare.com)

Diseases1

• There have been no systematic studies of diseases causing pleural effusion in Qatar. (who.int)

CAVITY1

• Presence of fluid in the PLEURAL CAVITY as a complication of malignant disease. (nih.gov)

Ovarian1

• Vidal A, Wachter C, Kohl Schwartz A, Dhakal C. A rare presentation of isolated right-sided pleural effusion in the context of ovarian hyperstimulation syndrome: A case report. (medscape.com)