MultilocularisTapewormCystsCestodeAlveolar echinococcosis in humansEpidemiology2018AbstractGranulosus sensuHepatic alveolar echinococcosisElisa echinococcosisSpeciesForms of echinococcosisNeotropical echinococcosisCystic diseaseDiagnosisClinicalPolycystic echinococcosisHumansParasiteAlbendazoleTaeniidaeEndemicHelminthicParasitic diseaseParasitesEpidemiologicalCanineOligarthrusFoxesSeroprevalenceInfection causedHumanSerumLiverEggsAdultImmunologyDiseaseZoonosisAfricaInsulinTurkeyTherapeuticDescribe
Multilocularis25
- We describe the spatial distribution of Echinococcus multilocularis in its main definitive host, the red fox, and the distribution of human cases of alveolar echinococcosis (AE) within a highly endemic focus in southern Germany (13.7-19.9/100,000 in 1992-2018). (biomedcentral.com)
- Echinococcus multilocularis is highly prevalent in foxes in all the studied areas. (biomedcentral.com)
- Currently, four species are recognized within the genus Echinococcus: E. granulosus (which causes cystic disease), E. multilocularis (which causes alveolar disease), E. vogeli (which causes polycystic disease), and E. oligarthrus (which causes polycystic disease). (med-chem.com)
- According to the directive 2003/99/ECC, a first survey for the presence in foxes of Echinococcus multilocularis and Toxocara canis was conducted in Brussels from 2001 to 2004. (nih.gov)
- Echinococcosis is an infection caused by either the Echinococcus granulosus or Echinococcus multilocularis tapeworm. (medlineplus.gov)
- Adult Echinococcus multilocularis superimposed on a Canadian dime. (avma.org)
- Alveolar echinococcosis (AE), caused by Echinococcus multilocularis, is a zoonotic helminthic disease that can mimic malignancy. (ajtmh.org)
- The insulin receptor ortholog EmIR of the fox-tapeworm Echinococcus multilocularis displays significant structural homology to the human insulin receptor (HIR) and has been suggested to be involved in insulin sensing mechanisms of the parasite's metacestode larval stage. (uni-wuerzburg.de)
- Der orthologe Insulinrezeptor EmIR des Fuchsbandwurmes Echinococcus multilocularis weist signifikante strukturelle Homologie zum humanen Insulinrezeptor (HIR) auf. (uni-wuerzburg.de)
- In dieser Arbeit wurden die Effekte von Wirtsinsulin auf Echinococcus Metacestoden-Vesikel und die vermutete Interaktion zwischen EmIR und Insulin von Säugern mittels biochemischer und zellbiologischer Der orthologe Insulinrezeptor EmIR des Fuchsbandwurmes Echinococcus multilocularis weist signifikante strukturelle Homologie zum humanen Insulinrezeptor (HIR) auf. (uni-wuerzburg.de)
- Echinococcus multilocularis (causative agent of AE) is widely distributed in the northern hemisphere where it is typically maintained in a wild animal cycle including canids as definitive hosts and rodents as intermediate hosts. (uzh.ch)
- Az előbbit az Echinococcus granulosus , az ut bbit az Echinococcus multilocularis nevű galandf reg l rv i okozz k. (oek.hu)
- A m sik galandf reg, az Echinococcus multilocularis fejlőd smenete ehhez hasonl , de itt a felnőtt galandf rgek ltal ban a r k k bel ben lősk dnek, a pet k a r k k r l k vel jutnak a szabadba, onnan a kisr gcs l kba (pl. vizipocok, eg r, cick ny), ritk n az emberbe is, s benn k fejlődnek ki a l rv k. (oek.hu)
- Growing fox populations have led to increasing concern about human alveolar echinococcosis, which is caused by the fox tapeworm Echinococcus multilocularis . (biomedcentral.com)
- Human alveolar echinococcosis (AE), caused by larval stages of the fox tapeworm Echinococcus multilocularis (EM), is a serious helminthic zoonosis [ 4 ]. (biomedcentral.com)
- In order to plan effective information campaigns, public knowledge about E. multilocularis , human alveolar echinococcosis and possible control measures were assessed by means of telephone interviews in four European Countries. (biomedcentral.com)
- Alveolar echinococcosis (AE), brought on by the larval stage of the cestode Echinococcus multilocularis, is a deadly illness in people. (ncbcs.org)
- Echinococcus multilocularis is a small tapeworm affecting wild and domestic carnivores and voles in a typical prey-predator life cycle. (biomedcentral.com)
- Echinococcus multilocularis was identified in foxes from two out of six eco-regions, in 30 fecal samples, accounting for 1.04% within the cestode positives at coproscopy. (biomedcentral.com)
- Echinococcus multilocularis is a canine tapeworm that can cause alveolar echinococcosis in humans through inadvertent ingestion of eggs shed by infected dogs. (bcmj.org)
- This characteristic was linked to a randomly selected according to landscape patterns, i.e., higher prevalence of Echinococcus multilocularis in dogs valley, valley entrance, piedmont, and flat land, were sur- and indicates that pasture type may affect E. multilocularis veyed. (cdc.gov)
- These methods are based on detect- ing surface indicators of small mammals, i.e., holes and Human alveolar echinococcosis (AE) is an infection feces, and are used to link small mammals and their habi- caused by Echinococcus multilocularis , a highly tats on large areas ( 10-12 ). (cdc.gov)
- The Echinococcosis (E. multilocularis) is an infection caused by the fox tapeworm. (arminlabs.com)
- In Europe the fox tapeworm (E. multilocularis) is the host of the alveolar Echinococcosis, a life-threatening worm infection for humans. (arminlabs.com)
- NT005 trade name] is indicated for the treatment of Echinococcus multilocularis and E. granulosus infections before or after surgery or where surgery is not suitable. (who.int)
Tapeworm3
- The echinococcoses are chronic, parasitic diseases that are acquired after ingestion of infective taeniid tapeworm eggs from certain species of the genus Echinococcus. (uzh.ch)
- The causative agent is the tapeworm Echinococcus granulosus, whose adult stage takes place in the small intestine of definitive hosts (dogs) and the development of the larval stage occurs mainly in the liver and lung of intermediate hosts such as sheep. (edu.pe)
- Hydatidosis or hydatid cyst is a prevalent zoonosis all over the world due to larval forms of the tapeworm of the genus Echinococcus. (bvsalud.org)
Cysts6
- These slow-growing masses, often called cysts, are also found in people that are infected with alveolar and polycystic echinococcosis. (wikipedia.org)
- The cysts found in those with cystic echinococcosis are usually filled with a clear fluid called hydatid fluid, are spherical, and typically consist of one compartment and are usually only found in one area of the body. (wikipedia.org)
- While the cysts found in those with alveolar and polycystic echinococcosis are similar to those found in those with cystic echinococcosis, the alveolar and polycystic echinococcosis cysts usually have multiple compartments and have infiltrative as opposed to expansive growth. (wikipedia.org)
- Most often, echinococcosis cysts do not cause symptoms and are found when an imaging test is done for another reason. (medlineplus.gov)
- Primary cysts of the brain showed a left parietal- common Echinococcus species causing are usually solitary. (who.int)
- Primary multiple temporal cystic lesion, minimally en- human infection are E. granulosus and cerebral hydatid cysts are quite unu- hanced after contrast. (who.int)
Cestode3
- These studies revealed significant differences between insulin signaling in Echinococcus and the related cestode parasite Taenia solium. (uni-wuerzburg.de)
- Echinococcus is a cestode. (who.int)
- Hydatid disease is a zoonotic infection caused by cestode species from the genus Echinococcus . (biomedcentral.com)
Alveolar echinococcosis in humans1
- Expert consensus for the diagnosis and treatment of cystic and alveolar echinococcosis in humans. (medscape.com)
Epidemiology3
- In 2020, an international effort of scientists, from 16 countries, led to a detailed consensus on terms to be used or rejected for the genetics, epidemiology, biology, immunology, and clinical aspects of echinococcosis. (wikipedia.org)
- Over the past two decades, numerous studies have addressed the epidemiology and distribution of these Echinococcus species worldwide, resulting in better-defined boundaries of the endemic areas. (uzh.ch)
- This chapter presents the global distribution of Echinococcus species and human AE and CE in maps and summarizes the global data on host assemblages, transmission, prevalence in animal definitive hosts, incidence in people and molecular epidemiology. (uzh.ch)
20183
- From 1992 to 2018, a total of nine human cases of alveolar echinococcosis were recorded in area I, five cases were recorded in study area III, and no cases were recorded in area II. (biomedcentral.com)
- Surgically confirmed cases of cystic echinococcosis from Baluchistan Province, Pakistan for the years 2011-2018. (medindia.net)
- A cross sectional study was conducted from January 2018 to April 2018 to determine the prevalence and associated risk factors of cystic echinococcosis in pig slaughtered at Addis Ababa abattoir enterprise, central part of Ethiopia. (ojafr.ir)
Abstract1
- ABSTRACT We performed a retrospective study to determine annual clinical incidence of human cystic echinococcosis (CE) in 14 Egyptian hospitals between January 1997 and December 1999. (who.int)
Granulosus sensu1
- Imported hepatopulmonary echinococcosis: first report of Echinococcus granulosus sensu stricto (G1) in Bolivia. (medindia.net)
Hepatic alveolar echinococcosis1
- Combined ultrasound and serologic screening for hepatic alveolar echinococcosis in central China. (ajtmh.org)
Elisa echinococcosis2
- Igg Elisa Laboratories manufactures the igg elisa echinococcosis serologic test reagents distributed by Genprice. (ayurvedandindia.com)
- The Igg Elisa Echinococcosis Serologic Test reagent is RUO (Research Use Only) to test human serum or cell culture lab samples. (ayurvedandindia.com)
Species6
- Intermediate hosts and humans may develop alveolar, cystic, or polycystic echinococcosis, depending on the parasite species involved ( 6 ). (cdc.gov)
- The global disease burden on wildlife species is unknown, as is the effect that echinococcosis may have on the overall fitness of wildlife animals and populations. (cdc.gov)
- Throughout the early decades of the 1900s, only 1 species of Echinococcus , E. granulosus , was formally recognized in North America and across the world. (cdc.gov)
- The species Echinococcus granulosus, Echinococcus ortleppi, Echinococcus canadensis and Echinococcus intermedius are the causative agents of CE with a worldwide distribution and a highly variable human disease burden in the different endemic areas depending upon human behavioural risk factors, the diversity and ecology of animal host assemblages and the genetic diversity within Echinococcus species which differ in their zoonotic potential and pathogenicity. (uzh.ch)
- Clinical manifestations and disease courses vary profoundly for the different species of Echinococcus. (uzh.ch)
- Consequently, we performed an Enzyme-linked Immunosorbent Assay (ELISA) test for Echinococcus species, which turned out to be negative. (biomedcentral.com)
Forms of echinococcosis1
- Cystic echinococcosis (CE) and alveolar echinococcosis (AE) are the key forms of echinococcosis that are of significant medical and public health concerns for humans. (medscape.com)
Neotropical echinococcosis1
- Cystic echinococcosis (CE) occurs worldwide, whereas, alveolar echinococcosis (AE) is restricted to the northern hemisphere, and neotropical echinococcosis (NE) has only been identified in Central and South America. (uzh.ch)
Cystic disease1
- Echinococcosis is a parasitic disease of tapeworms of the Echinococcus type characterized by production of unilocular or multilocular cystic disease of lung and liver. (capsulehealth.one)
Diagnosis1
- This case report aims to demonstrate the case of a patient from an Echinococcus -endemic area with highly suspected hydatid disease and an unexpected outcome with a challenging differential diagnosis. (biomedcentral.com)
Clinical4
- The current clinical therapeutic medicine against echinococcosis is albendazole, although it caused serious side effects in patients. (hindawi.com)
- Albendazole is the most common clinical drug to treat echinococcosis [ 4 ]. (hindawi.com)
- Evaluation of Cystic Echinococcosis Cases in Terms of Sociodemographic, Clinical and Hospitalization Features in Karaman Province, Turkey. (medindia.net)
- Echinococcosis of the heart: clinical and echocardiographic features in 12 patients. (medscape.com)
Polycystic echinococcosis1
- Less common forms include polycystic echinococcosis and unicystic echinococcosis. (wikipedia.org)
Humans4
- In humans, ingested eggs can be mainly distributed to liver and lung, leading to cystic echinococcosis (CE) and alveolar echinococcosis (AE). (hindawi.com)
- Human echinococcosis is a zoonotic infection (i.e it is a disease of animal kingdom that sometimes can be transmitted to humans). (medindia.net)
- The aim of the present study was to estimate the prevalence of AE in humans in 2 districts of south Gansu Province, China, by use of ultrasound and Echinococcus serology. (ajtmh.org)
- Echinococcus granulosus is the most frequent form of echinococcal infection in humans. (bvsalud.org)
Parasite2
- Human insulin, exogenously added to in vitro cultivated parasite larvae, (i) significantly stimulated parasite survival and growth, (ii) induced DNA de novo synthesis in Echinococcus, (iii) affected overall protein phosphorylation in the parasite, and (iv) specifically induced the phosphorylation of the parasite's Erk-like MAP kinase orthologue EmMPK1. (uni-wuerzburg.de)
- It contains clear liquid and the young form of a parasite called a dog tape worm or echinococcus. (britishlivertrust.org.uk)
Albendazole8
- In order to explore the effect and mechanism of SA treatment against echinococcosis, we established animal echinococcosis model and treated rats with albendazole alone, alkaloids alone, and combined therapy. (hindawi.com)
- Furthermore, it has been reported that Echinococcus granulosus protoscolices have developed resistance to albendazole [ 4 - 6 ]. (hindawi.com)
- Clinically, its seeds decoction is combined with albendazole to treat echinococcosis [ 9 ]. (hindawi.com)
- In the present study, we not only investigated the therapeutic effect of the combinational treatment of Sophora moorcroftiana alkaloids and albendazole against echinococcosis in an experimental rats model, but also explored the underlying molecular mechanism of this strategy by proteomics. (hindawi.com)
- Albendazole and mebendazole are the only anthelmintics effective against cystic echinococcosis. (medscape.com)
- [ 42 ] When surgery cannot be avoided, presurgical use of albendazole in echinococcus infestations reduced risk of recurrence and/or facilitated surgery by reducing intracystic pressure. (medscape.com)
- Treatment of echinococcosis for patients weighing more than 60 kg is albendazole administered PO with meals in a dose of 400 mg twice daily for 28 days. (medscape.com)
- Programme for ultrasound diagnoses and treatment with albendazole of cystic echinococcosis in asymptomatic carriers: 10 years of follow-up of cases. (medscape.com)
Taeniidae1
- Echinococcosis is the general term used to describe four disease forms caused by the larval stage of Echinococcus tapeworms, the smallest tapeworms in the Taeniidae family. (medscape.com)
Endemic1
- Echinococcosis is a worldwide anthropozoonosis which is highly endemic over large animal husbandry areas in northwestern China. (hindawi.com)
Helminthic1
- Alveolar echinococcosis (AE) and cystic echinococcosis (CE) are severe helminthic zoonoses. (uzh.ch)
Parasitic disease1
- Echinococcosis is a parasitic disease caused by tapeworms of the Echinococcus type. (wikipedia.org)
Parasites1
- Parasites - echinococcosis. (medlineplus.gov)
Epidemiological1
- To evaluate the serological, radiological and epidemiological analysis of suspected cystic echinococcosis patients, and to assess the positivity rate in the region. (org.pk)
Canine1
- Kolapo TU , Hay A , Gesy KM , Canine alveolar echinococcosis: an emerging and costly introduced problem in North America . (avma.org)
Oligarthrus1
- Caused by Echinococcus vogeli and very rarely, Echinococcus oligarthrus . (capsulehealth.one)
Foxes1
- The Echinococcus tapeworm's life cycle (see image below) involves a definitive host, usually a dog (although foxes and coyotes have also been implicated), and intermediate hosts such as sheep, goats, and swine. (medscape.com)
Seroprevalence1
- Seroprevalence of Echinococcus spp. (medindia.net)
Infection caused1
- Cystic echinococcosis is a zoonotic infection caused by Echinococcus granulosus . (biomedcentral.com)
Human2
- The type of disease that occurs in human patients depends on the type of Echinococcus causing the infection. (wikipedia.org)
- Human cystic echinococcosis (CE) (cystic transmission is intense in Egypt. (who.int)
Serum1
- Description: Enzyme-linked immunosorbent assay kit for quantification of Dog echinococcus antibody (IgG) in samples from serum, plasma, tissue homogenates and other biological fluids. (ayurvedandindia.com)
Liver2
- In all, we consider that the combinational treatment displayed better therapeutic effects against liver echinococcosis as well as alleviated liver injury, which could be considered as an effective strategy to treat echinococcosis clinically. (hindawi.com)
- There was no clear relationship between the cystic tumor and the liver, which led to the assumption of primary extrahepatic cystic echinococcosis. (biomedcentral.com)
Eggs1
- Echinococcus eggs deposited in soil can remain viable for a year. (medscape.com)
Adult1
- The adult Echinococcus granulosus (3 to 6 mm long) [1] resides in the small bowel of the definitive hosts (dogs or other carnivores). (capsulehealth.one)
Immunology1
- Immunology of echinococcus infections. (medindia.net)
Disease4
- The two main types of the disease are cystic echinococcosis and alveolar echinococcosis. (wikipedia.org)
- In people who are infected with E. granulosus and therefore have cystic echinococcosis, the disease develops as a slow-growing mass in the body. (wikipedia.org)
- Diagram of the Echinococcus life cycle, provided by the Centers for Disease Control and Prevention. (medscape.com)
- Although echinococcosis is a preventable and treatable disease, echinococcosis continues to be a major public health problem in many countries [ 4 ]. (biomedcentral.com)
Zoonosis2
- La equinococosis quística representa una grave zoonosis parasitaria en nuestro país y otros países en desarrollo dedicados a la ganadería. (edu.pe)
- Cystic echinococcosis is a serious parasitic zoonosis in our country and other developing countries dedicated to livestock. (edu.pe)
Africa2
- Cystic echinococcosis is also widely found throughout the region comprising Arab North Africa and the Middle East. (med-chem.com)
- Alveolar and cystic echinococcosis are emerging and reemerging in Europe, Africa, and Asia. (cdc.gov)
Insulin4
- In the present work, the effects of host insulin on Echinococcus metacestode vesicles and the proposed interaction between EmIR and mammalian insulin have been studied using biochemical and cell-biological approaches. (uni-wuerzburg.de)
- These results clearly indicated that Echinococcus metacestode vesicles are able to sense exogenous host insulin which induces a mitogenic response. (uni-wuerzburg.de)
- These results indicated the capability of EmIR to sense and to transmit host insulin signals to the Echinococcus signaling machinery. (uni-wuerzburg.de)
- In dieser Arbeit wurden die Effekte von Wirtsinsulin auf Echinococcus Metacestoden-Vesikel und die vermutete Interaktion zwischen EmIR und Insulin von Säugern mittels biochemischer und zellbiologischer experimenteller Ansätze untersucht. (uni-wuerzburg.de)
Turkey4
- The retrospective study was conducted at Bursa Uludag University Hospital, Bursa, Turkey, and comprised data from January 2009 to December 2017 related to patients of either gender with suspected cystic echinococcosis who underwent indirect haemagglutination testing. (org.pk)
- Cystic echinococcosis was found to be a public health problem South Marmara region of Turkey. (org.pk)
- Cystic echinococcosis is one of the most important zoonotic diseases in Turkey. (bezmialem.edu.tr)
- The aim of this study was for the molecular analysis of Echinococcus granulosus isolates from different regions of Turkey. (bezmialem.edu.tr)
Therapeutic1
- Thus, it is urgent to develop new therapeutic strategies against echinococcosis. (hindawi.com)
Describe1
- We describe the context of Echinococcus spp. (cdc.gov)