• Cyclin B Export to the Cytoplasm via the Nup62 Subcomplex and Subsequent Rapid Nuclear Import Are Required for the Initiation of Drosophila Male Meiosis. (nih.gov)
  • second, we show that expression of C-terminally tagged Gorab disrupts Golgi functions in cytokinesis of male meiosis, a dominant phenotype overcome by mutations preventing Golgi targeting. (uni-koeln.de)
  • However it is possible for sexually antagonistic variation, in combination with the very limited recombination observed in frog male meiosis, to select for the maintenance of such a sex-ratio distorting, sex-determining allele. (parisveltsos.com)
  • In Drosophila , the BX-C cluster contains the three most posterior Hox genes, where their collinear activation incorporates progressive replacement of histone modifications, reorganization of 3D chromatin architecture and sequential activation of boundary elements and cis -regulatory regions. (biorxiv.org)
  • In Drosophila males, meiotic prophase lasts 3.5 days, during which spermatocytes upregulate of over 1800 genes and grow 25-fold. (stanford.edu)
  • We identified >500 Drosophila genes that express mRNA isoforms with a long 3' UTR in proliferating spermatogonia but a short 3' UTR in differentiating spermatocytes due to APA. (stanford.edu)
  • Two principal classes of genes were identified: (i) genes primarily involved in meiosis, namely in synaptonemal complex formation, asymmetric division and oocyte maturation and (ii) genes safeguarding cell maintenance (piRNA and DNA repair pathways). (unimi.it)
  • Independent assortment of genes is also based on recombination of chromosomes during meiosis which results in a further assortment of genes or characters. (microbenotes.com)
  • During meiosis, the chromosomes are separated so that only half the genes are transported to the gametes. (microbenotes.com)
  • The Long-Term Public Health Implications for the analysis of differentially expressed genes in Drosophila. (kameshwarmahadev.com)
  • It seems probable that the scheme outlined in this paper will apply for the case of inversions that do not include the locus of the spindle attachment and for other chromosome aberrations in which crossing-over gives rise to chromatids with two spindle attachments, and where the conditions of meiosis are such that (a) the meiotic spindles are oriented so that the reduced nuclei lie approximately on a single straight line, and (b) only one of the terminal nuclei functions in further development. (caltech.edu)
  • Sciara has several unique biological properties that make it an excellent model, particularly their monopolar spindle in meiosis and chromosome movement, including non-disjunction during meiosis and chromosome elimination in the early embryo. (newswise.com)
  • Oocyte meiosis, important to all animal life cycles yet unlike all other instances of animal cell division, occurs completely without the aid of spindle -coordinating centrosomes . (wikipedia.org)
  • A requirement for the Abnormal Spindle protein to organise microtubules of the central spindle for cytokinesis in Drosophila. (unisi.it)
  • His research in Establishment of sister chromatid cohesion intersects with topics in Meiosis II, Spindle apparatus and Kinetochore. (research.com)
  • Tseng BS, Tan L, Kapoor TM, Funabiki H. Spc105 recruits PP1 to bind Spc105KNL1 and silence the spindle checkpoint is less persistent in meiosis I has a more robust to confounding (Fig 3B), allowing larger p values approximate the SDE estimator and result in bending. (kameshwarmahadev.com)
  • DksA-DnaJ redox interactions provide a theoretical explanation for why spindle checkpoint activity with direct comparisons between meiosis and mitosis in cells containing the gene of interest were used to generate cDNA using 100 U M-MLV reverse transcriptase (Promega). (kameshwarmahadev.com)
  • Since Rcd-1 is a regulator of differentiation in other species, it suggests that Rcd-1r may serve a similar role during spermatogonial differentiation in Drosophila . (plos.org)
  • I will be discussing our work on the regulation of proliferation and differentiation in the Drosophila male germ line adult stem cell lineage and the surprising contributions of cell type specific alternative mRNA processing to cell state changes. (genetics-gsa.org)
  • Achiasmate Meiosis refers to meiosis without chiasmata, which are structures that are necessary for recombination to occur and that usually aid in the segregation of non-sister homologs. (wikipedia.org)
  • CSN5, a subunit of eight protein COP9 signalosome complex (CSN) plays significant role in the repair of recombination-induced DSB during Drosophila oogenesis. (dpmb.ac.in)
  • Programmed DNA double-strand breaks (DSBs) made during meiosis are repaired by recombination with the homologous chromosome to generate, at selected sites, reciprocal crossovers that are critical for the proper separation of homologs in the first meiotic division. (bvsalud.org)
  • Drosophila repleta Wollaston and D. neorepketa Patterson and Wheeler are closely similar species, the former widely distributed and the latter known from Guatemala. (caltech.edu)
  • There is now in progress in several laboratories a comparative study of the genetics of the species of Drosophila. (caltech.edu)
  • It is theorized that this failure during the meiotic cycle is what creates the diploid eggs and that likely sister chromatids are separated during meiosis instead of the homologs in this species. (wikipedia.org)
  • A deeper understanding of how meiosis proceeds in these achiasmate species is still under investigation. (wikipedia.org)
  • On the other hand, pericentric inversions often lead to decreased fertility in females [ 6 , 7 ], which may also explain the preponderance of polymorphic paracentric over pericentric inversions in species like Drosophila spp. (biomedcentral.com)
  • 2013). Drosophila americana as a model species for comparative studies on the molecular basis of phenotypic variation . (up.pt)
  • 2011). A comparative study of the short term cold resistance response in distantly related Drosophila species: The role of regucalcin and Frost . (up.pt)
  • This research was inspired by frogs, but it applies to any species with achiasmatic meiosis in one sex, such as Drosophila and many fishes. (parisveltsos.com)
  • The award will be presented to Gerbi at the 58th Annual Drosophila Research Conference, March 29-April 2, 2017, San Diego, CA. To learn more about the GSA awards, and to view a list of previous recipients, please see http://www.genetics-gsa.org/awards . (newswise.com)
  • The Department of Genetics has a strong history of Drosophila research which has continued to the present day. (cam.ac.uk)
  • His study in Genetics concentrates on Establishment of sister chromatid cohesion, Meiosis, Centromere, Chromosome segregation and Origin recognition complex. (research.com)
  • We demonstrate that a Drosophila Golgi protein, Gorab, is present not only in the trans-Golgi but also in the centriole cartwheel where, complexed to Sas6, it is required for centriole duplication. (uni-koeln.de)
  • The Cell cycle study combines topics in areas such as Ploidy, Mitosis, Drosophila Protein and Cell fate determination. (research.com)
  • Race B females of Drosophila pseudoöbscura crossed to race A males produce sterile F1 hybrid males having visibly small testes. (caltech.edu)
  • In fly males, the competition for the driver X during meiosis is the Y. The driver X in flies ensures all sperm are X. In your human females, competition for the driver X! (stackexchange.com)
  • Incomplete penetrance of sex determination in frogs, and achiasmatic meiosis in males, allows for interesting possibilities in the evolution of a new sex chromosome. (parisveltsos.com)
  • We found that deletion of NUP2 delayed pairing and synapsis during meiosis, and led to decreased spore viability, similar to the ndj1Δ mutant phenotype. (biorxiv.org)
  • After this initial stage of maternal control, which lasts for 1-2 mitotic divisions in mammals and 13 mitotic divisions in Drosophila, widespread transcription begins from the zygotic nuclei ( Tadros and Lipshitz, 2009 ). (elifesciences.org)
  • Functional studies using a Drosophila model, when applicable, supported the conserved role of the MOV10 armitage and DMRT3 dmrt93B orthologues in female fertility. (unimi.it)
  • Using histone H2AvD-RFP and protamineB-eGFP expressing flies the development of isolated cysts through meiosis and the H-P switch was observed in in vivo-time-lapse fluorescence microscopy. (uni-marburg.de)
  • Meiosis arrest mutants fail to proceed to meiosis and accumulate SpC cysts. (biomedcentral.com)
  • Chromosome segregation errors during meiosis are the leading cause of birth defects and developmental delays in humans ( H assold and H unt 2001 ). (biorxiv.org)
  • The law of independent assortment, like the law of segregation , is based on meiosis cell division that occurs during sexual reproduction. (microbenotes.com)
  • Drosophila CIAPIN1 homologue is required for follicle cell proliferation and survival. (nih.gov)
  • Removal of the oocyte from the follicle causes meiosis to progress in the oocyte. (wikipedia.org)
  • S. ludwigii also creates strong connections between the tetrads produced by meiosis to promote the breeding (automixis) within the tetrad. (wikipedia.org)
  • The results of this work were used in the assembly of a working model for the molecular mechanism of the H-P switch in Drosophila. (uni-marburg.de)
  • In vertebrates as well as in Drosophila an increase in histone H4 acetylation precedes the H-P switch, while the switch is accompanied by introduction of DNA breaks. (uni-marburg.de)
  • Thus, histone H4 acetylation alone is not sufficient to be the start-signal of the H-P switch in Drosophila. (uni-marburg.de)
  • The HAT responsible for histone H4 acetylation in the H-P switch of Drosophila is not known so far. (uni-marburg.de)
  • This fact has been used, in the present experiments, to study the distribution of the fragment at meiosis. (caltech.edu)
  • Heart muscle cells die en masse after injury, yet the adult mammalian heart retains little capacity to regenerate them. (natureasia.com)
  • Aster self-organization at meiosis: a conserved mechanism in insect parthenogenesis? (unisi.it)
  • This phenomenon was first described in Drosophila (where it is called the sex ratio trait) (Gershenson, 1928), but has since been found in a wide range of taxa, including rodents, plants and numerous flies (Diptera) (Jaenike, 2001). (stackexchange.com)
  • In Xenopus, zebrafish, and Drosophila the major activation of zygotic transcription occurs as the cell cycle lengthens and gastrulation begins, a developmental period referred to as the midblastula transition. (elifesciences.org)