Neurodegenerative DiseasesDisease SusceptibilityGenetic Predisposition to DiseaseGenetic LinkageChromosome MappingGenetic LociGenetic MarkersPolymorphism, Single NucleotideGenotypeHaplotypesPedigreeAllelesLod ScoreLinkage DisequilibriumNerve DegenerationAlzheimer DiseasePolymorphism, GeneticMutationGenome-Wide Association StudyGene FrequencyHuntington DiseasePhenotypeBrainGenetic Diseases, InbornAmyotrophic Lateral SclerosisNeuronsQuantitative Trait LociModels, GeneticDisease Models, Animaltau ProteinsParkinson DiseaseGenetic VariationMolecular Sequence Dataalpha-SynucleinMicrosatellite RepeatsCase-Control StudiesGenetic HeterogeneityNerve Tissue ProteinsGenome, HumanPrionsMice, TransgenicTauopathiesNeuroprotective AgentsPrion DiseasesGenes, DominantChromosomes, Human, Pair 6Mice, Inbred C57BLBase SequenceInclusion BodiesHeredodegenerative Disorders, Nervous SystemFriedreich AtaxiaTrinucleotide Repeat ExpansionProteostasis DeficienciesConsanguinityDiseaseAmino Acid SequenceMicrogliaMicrobial Sensitivity TestsGenetic Association StudiesPhysical Chromosome MappingNuclear FamilyHomozygoteChromosomes, Human, Pair 2SynucleinsCell DeathOxidative StressHeterozygoteAmyloid beta-PeptidesGenetics, PopulationPenetrancePolymerase Chain ReactionCells, CulturedSpinocerebellar AtaxiasGenes, RecessiveCrohn DiseaseGene Expression RegulationAge of OnsetFrontotemporal Lobar DegenerationSequence Analysis, DNAGenetic TestingAgingMultifactorial InheritanceMitochondriaSpinocerebellar DegenerationsHLA-DQ AntigensSignal TransductionImmunity, InnateFrontotemporal DementiaDNA Mutational AnalysisCrosses, GeneticChromosomes, Human, Pair 1Polymorphism, Restriction Fragment LengthModels, BiologicalNod2 Signaling Adaptor ProteinHLA-DRB1 ChainsX ChromosomeEpistasis, GeneticAutophagyHLA-DQ beta-ChainsMice, Knockout