Symptoms: Diffuse joint and bone pain (especially of spine, pelvis, and legs) Muscle weakness Difficulty walking, often with a waddling gait Hypocalcemia (positive Chvostek sign) Compressed vertebrae and diminished stature Pelvic flattening Weak, soft bones Easy fracturing Bending of bones Osteomalacia in adults starts insidiously as aches and pains in the lumbar (lower back) region and thighs before spreading to the arms and ribs. (wikipedia.org)
Sensitivity1
The pain is symmetrical, non-radiating and accompanied by sensitivity in the involved bones. (wikipedia.org)
Body1
Signs and symptoms can include diffuse body pains, muscle weakness, and fragility of the bones. (wikipedia.org)
Disease3
Osteomalacia is a disease characterized by the softening of the bones caused by impaired bone metabolism primarily due to inadequate levels of available phosphate, calcium, and vitamin D, or because of resorption of calcium. (wikipedia.org)
Many of the effects of the disease overlap with the more common osteoporosis, but the two diseases are significantly different. (wikipedia.org)
Clinical definitions of the various myeloma subtypes have been updated, as have the imaging definitions of what constitutes bone marrow disease and individual bony involvement. (medscape.com)