Differentiation carcinoma basal cell. Medical search. Frequent questions

Even though immunohistochemical comparisons of microcystic adnexal carcinoma vs infiltrative basal cell carcinoma and desmoplastic trichoepithelioma exist, they are mostly restricted to the use of a single stain. (dadospdf.com)
We found that the majority of microcystic adnexal carcinoma (92%) and desmoplastic trichoepithelioma (100%) cases expressed CK15 while the infiltrative basal cell carcinoma and squamous cell carcinoma cases were all negative. (dadospdf.com)
While the neoplastic cells were negative, luminal staining of ductal structures was noted for CK7, CD15 and CEA in some of the microcystic adnexal carcinoma, desmoplastic trichoepithelioma and squamous cell carcinoma with ductal differentiation cases. (dadospdf.com)
BerEP4 expression was noted in 38% of microcystic adnexal carcinoma, 57% of desmoplastic trichoepithelioma, 100% of infiltrative basal cell carcinoma, and 38% of squamous cell carcinoma. (dadospdf.com)
published online 7 December 2007 histopathologic perspective, the main differential diagnosis for microcystic adnexal carcinoma, a stratified, infiltrating neoplasm characterized by a superficial component of keratinous cysts and a deeper component of smaller nests and strands of cells embedded in a markedly hyalinized stroma, is sclerosing/infiltrative basal cell carcinoma and desmoplastic trichoepithelioma. (dadospdf.com)
While local recurrence is reported in 50% of cases of microcystic adnexal carcinoma with positive margins, 40-60% of patients experience one or more local recurrences anywhere from 6 months to 30 years after standard wide local excision.4,6,7,9-11 Thus, while the standard of care for microcystic adnexal carcinoma is wide local excision, no further management is mandated for a desmoplastic trichoepithelioma. (dadospdf.com)
Criteria for histologic differentiation of desmoplastic trichoepithelioma (sclerosing epithelial hamartoma) from morphea-like basal-cell carcinoma. (asocolderma.org.co)
21. Hartschuh W, Schulz T. Merkel cells are integral constituents of desmoplastic trichoepithelioma: an immunohistochemical and electron microscopic study. (asocolderma.org.co)
Does the panel of cytokeratin 20 and androgen receptor antibodies differentiate desmoplastic trichoepithelioma from morpheaform / infiltrative basal cell carcinoma? (asocolderma.org.co)
23. Thewes M, Worret WI, Engst R, Ring J. Stromelysin-3: a potent marker for histopathologic differentiation between desmoplastic trichoepithelioma and morphealike basal cell carcinoma. (asocolderma.org.co)

Sixty percent of infiltrative basal cell carcinoma, 31% of microcystic adnexal carcinoma, and 25% of squamous cell carcinoma express CD10. (dadospdf.com)
In conclusion, we found CK15 to be a useful marker in distinguishing microcystic adnexal carcinoma from infiltrative basal cell carcinoma and squamous cell carcinoma with ductal differentiation. (dadospdf.com)
Pathology and external consultation confirmed syringomatous carcinoma due to the infiltrative growth pattern of a dermal tumor. (appliedradiationoncology.com)
Histopathological examination showed low-grade minimally infiltrative multinodular tumor with biphasic differentiation comprising ductal epithelial cells and clear myoepithelial cells. (ijhnp.org)

Diagnosis of TBL is challenging given its resemblance to basal cell carcinoma (BCC) but is important given possible malignant transformation and potential metastasis. (karger.com)
Therefore, the authors concluded to a probable hyperplasic status in benign or malignant neoplasic cells. (globale-dermatologie.com)
however, direct antiproliferative effects against malignant cells and modulation of host immune response may be important. (medscape.com)
Of the different tumour types arising in epithelial tissues, squamous cell carcinoma (SCC) is the most malignant and has the highest metastatic potential. (ukri.org)
Sebaceous carcinoma is a very rare, aggressive, malignant tumor arising in the adnexal epithelium of the sebaceous gland. (biomedcentral.com)
Sarcomatoid renal cell carcinoma (SRCC) is currently defined in the 2004 World Health Organization (WHO) classification of renal tumors as any histologic type of renal cell carcinoma (RCC) containing foci of high-grade malignant spindle cells. (medscape.com)
RR CC was named for its morphologic resemblance to pediatric malignant rhabdoid tumor (MRT) of the kidney, which is a highly aggressive tumor characterized by cells that resemble rhabdomyoblasts and by genetic alterations involving chromosome 22, particularly the hSNF5/INI1 gene on 22q11.2. (medscape.com)
Squamous cell carcinoma of varying degrees of differentiation is observed in 90% of patients with malignant tumors of the vulva. (med-blog.com)
The most common benign and malignant neoplasms arising in this disorder include trichilemmoma, syringocystadenoma papilliferum, keratoacanthoma, apocrine cystadenoma and basal cell carcinoma. (ijcrr.com)
Epithelial-myoepithelial carcinoma (EMC) is a rare and low-grade malignant tumor of the salivary gland. (ijhnp.org)
Epithelial myoepithelial carcinoma (EMC) is a rare malignant salivary gland tumor with biphasic pattern accounting for nearly 2% of malignant salivary gland tumors and less than 1% of all salivary gland epithelial neoplasm. (ijhnp.org)
In neoplastic myoepithelial cells, CD10 expression was found in 25.71% of benign and 32.43% of malignant neoplasms. (qxmd.com)
CK5 is expressed in the basal epithelium of the lung and its overexpression is an indicator of malignant squamous differentiation in pulmonary lesions. (roche.com)
1,3 Malignant squamous differentiation is characteristic of the squamous cell carcinoma (SCCA) subtype of non-small cell lung cancer (NSCLC). (roche.com)
In addition, CK5 is expressed in mesothelial cells of the pulmonary pleura and is overexpressed in epithelioid malignant mesothelioma (MM). 6 CK5 is consistently absent in pulmonary ADC that confounds the diagnosis of epithelioid MM. 6,7 Thus, detection of CK5 with anti-Cytokeratin 5/6 (D5/16B4) antibody can be used to aid in the differential diagnosis of epithelioid MM from lung ADC. (roche.com)
9,10 Thus, detection of CK5 in prostatic basal cells with anti-Cytokeratin 5/6 (D5/16B4) antibody may be used to aid in the differentiation of benign and malignant prostate lesions. (roche.com)
Coexisting foamy and nonfoamy adenocarcinoma with glandular differentiation devoid of basal cell lining is helpful in clarifying their malignant nature. (medscape.com)
Spindle cell tumors were the most common malignant tumors, with 87,2% of the cases. (bvsalud.org)

Bowen, 2004} detected keratinocyte proliferation by PCNA (proliferating cell nuclear antigen) marking, 13,9% of keratinocytes were stained, compared with 6,4% in normal skin. (globale-dermatologie.com)
It interferes with DNA synthesis by blocking methylation of deoxyuridylic acid and inhibiting thymidylate synthetase and, subsequently, cell proliferation. (medscape.com)
The impairment of proliferation, differentiation, and mineralization in osteoblast is the main pathophysiological mechanism of osteoporosis, which has been proven by previous studies ( 4 , 5 ). (frontiersin.org)
ZNF148 suppressed cell proliferation and migration and was transcriptionally repressed by MYC in breast cancer. (nature.com)
Depletion of ZNF148 by short hairpin RNA (shRNA) and CRISPR/Cas9 increased triple-negative breast cancer (TNBC) cell proliferation and migration. (nature.com)
There is not cured for MM. Tan II A has been reported to reduce cancer cell proliferation. (biomedcentral.com)
We sought to explore the possible mechanism by which Tan II A regulated cell proliferation through autophagy signaling pathway in A375 cells. (biomedcentral.com)
Cell proliferation was assessed by using methyl thiazol tetrazolium (MTT) assay. (biomedcentral.com)
We found that Tan IIA inhibited melanoma A375, MV3, and M14 cell proliferation in dose and time dependent manner. (biomedcentral.com)
We concluded that Tan II A reduced A375 cells proliferation by activation of autophagy production, blocked PI3K- Akt - mTOR - p70S6K1 signaling pathway, increased autophagic related gene beclin-1, LC3-II protein expressions and induced autophagocytosis. (biomedcentral.com)
In esophageal cancer, radiation therapy was found inducing autophagy in cancer cells, promoting cancer cell proliferation and causing treatment resistance [ 10 ]. (biomedcentral.com)
Other reports suggested that autophage suppressed cancer development in early stage and promoted cancer cell proliferation in later stage [ 4 ]. (biomedcentral.com)
Lipotransfection and MTT were applied for proliferation assessment in U87-MG cells. (hindawi.com)
Additionally, lumen differentiation, local clear cell-like change, collagen proliferation and sclerosis around the lower tumor tissue were observed. (oatext.com)
The Notch signaling pathway plays a key role in the proliferation and differentiation of many tissues. (molvis.org)
In vitro studies based on MCF-7 cell proliferation and induction of vitellogenin in primary culture of rainbow trout hepatocytes. (cdc.gov)

while only two microcystic adnexal carcinoma cases (15%) and one squamous cell carcinoma with ductal differentiation (12%) expressed CK7 in the remaining three tumor categories. (dadospdf.com)
First reported in 1982 by Goldstein et al,1 microcystic adnexal carcinoma has been referred to by a variety of names-all of which allude to the clinical behavior and histopathologic features of this lesion. (dadospdf.com)
In addition, we noticed misdiagnosis of a few cases of microcystic adnexal carcinoma as squamous cell carcinoma at our institution-most likely a consequence of the biopsy technique (superficial shave). (dadospdf.com)
The differentiation of microcystic adnexal carcinoma from any of these other entities is not merely semantic but extremely relevant to clinical management. (dadospdf.com)
Microcystic adnexal carcinoma MP Hoang et al 179 believed to account for its high recurrence rate. (dadospdf.com)
3 Histologically, the absence of keratinizing cysts and squamous differentiation (ie, islands with parakeratotic keratinization) distinguish SC from other sclerosing adnexal tumors such as microcystic adnexal carcinoma (MAC) and squamoid eccrine ductal carcinoma (SEDC), respectively. (appliedradiationoncology.com)

Salivary gland tumors with myoepithelial differentiation such as adenoid cystic carcinoma (ACC), PA, myoepithelioma, basal cell adenoma (BCA), basal cell adenocarcinoma (BCAC), and myoepithelial carcinoma are to be considered in the differential diagnoses. (ijhnp.org)
We examined 72 salivary tumors with myoepithelial differentiation using immunohistochemical technique to detect CD10. (qxmd.com)

Biopsy of the area confirmed squamous cell carcinoma (SCC), stage 1. (appliedradiationoncology.com)
Biopsy of the left nose revealed recurrent syringomatous carcinoma that extended deeply up to but not invading the level of the cartilage. (appliedradiationoncology.com)
Permanent biopsy revealed that the skin lesion was a PC with basal cells and squamous differentiation. (e-acfs.org)
Evaluation of optical coherence tomography as a means of identifying earlier stage basal cell carcinomas while reducing the use of diagnostic biopsy. (vivosight.com)
[ 4 ] This is especially the case when they occur in seemingly infiltrating nests, cords, or single cells on small biopsy specimens. (medscape.com)

Both clear cell and sclerotic basal cell carcinomas are extremely rare pathological types of basal cell carcinoma. (oatext.com)
The diagnosis should be established prior to treatment, since this method has not been proven effective in other types of basal cell carcinomas. (nih.gov)

According to the degree of differentiation of carcinoma in situ, can be divided into well differentiated (large cell carcinoma) and poor differentiation (small cell carcinoma) of the two types. (cancerlive.net)

Around 80% of all human cancers develop in the epithelium, and of the different epithelial cancer types, Squamous Cell Carcinoma (SCC) is the most deadly. (ukri.org)
Alternatively, it is possible that SCC instead initially develops from the differentiated keratin 1-positive and keratin 14-negative suprabasal layer of the epithelium, which sits above the basal layer. (ukri.org)
Fig.3) Outer layer of epithelium was lined by cuboidal cells and the inner layer by columnar cells, a few of which showed decapitation secretion. (ijcrr.com)
Poorly differentiated carcinoma in situ in the epithelium and sometimes cancer cells can appear well differentiated group, even bead keratosis. (cancerlive.net)
The inverse correlation between Notch signaling and the proliferative status of the corneal epithelium is consistent with the idea that Notch plays a role in corneal epithelial differentiation. (molvis.org)
The corneal epithelium is continually losing cells due to desquamation (primarily via the blink reflex) and thus must replace these cells to maintain homeostasis. (molvis.org)
Cells which lack ER expression at diagnosis arise from an ER compart- were harvested at 60 - 80% confluency and used as a reference in all hybrid- ment within the mammary epithelium or represent evolution from an izations. (lu.se)

African-Americans have an increased risk for esophageal squamous cell carcinoma (ESCC), the subtype that shows marked variation in geographic frequency. (biomedcentral.com)
In cases in which the histologic subtype of the RCC component is not recognizable, the tumor is designated as unclassified RCC with sarcomatoid differentiation. (medscape.com)
EFNA4 was predicted to have poor OS and RFS in breast cancers, especially in luminal B, basal-like subtype, and patients treated with adjuvant chemotherapy. (hindawi.com)

For the differentiation of BCC from BCC-imitators (such as squamous cell carcinoma, actinic and seborrheic keratosis, dermal nevus, and inflammatory conditions), the researchers analysed 303 lesions, including 173 BCC and 130 BCC-imitators. (hospitalhealthcare.com)
Differentiation of seborrheic keratosis from basal cell carcinoma, nevi and melanoma by RGB autofluorescence imaging. (unza.zm)

The most common chemotherapeutic agent used in superficial basal cell carcinoma is topical 5-fluorouracil. (medscape.com)
In the 5% strength, it is also useful in the treatment of superficial basal cell carcinomas when conventional methods are impractical, such as with multiple lesions or difficult treatment sites. (nih.gov)

In vivo differentiation of common basal cell carcinoma subtypes by microvascular and structural imaging using dynamic optical coherence tomography. (vivosight.com)
Epithelial ovarian cancer is the major ovarian malignancy and comprises five histological subtypes: serous, mucinous, endometrioid, transitional and clear cell [ 3 , 4 ]. (jcancer.org)
This signature provided significant prognostic stratification in The Cancer Genome Atlas breast cancer patients (n = 1100), as well as basal-like and luminal A subtypes, and was associated with distinct immune infiltration and activities. (cdc.gov)

The term organoid nevus may be used to emphasize the admixture of epidermal cells often evident in individual lesions of epidermal nevi. (medscape.com)
The metastatic lesions that originate from the breast or colon are prone to mimic the cutaneous mucinous carcinoma 4. (constiintaortodoxa.ro)
The first clinical impression is that of a cyst, basal cell carcinoma, keratoacantoma, nevus, apocrine hidrocystoma, another location primary tumour metastasis and in certain circumstances the clinical differentiation includes vascular lesions as those found in the Kaposi sarcoma 5. (constiintaortodoxa.ro)
Carcinoma of cervix is classified as per the WHO classification into primary tumors which are predominantly epithelial tumors, mesenchymal tumors and tumor like lesions, mixed epithelial stromal tumors, melanocytic, germ cell, and lymphoid tumors. (cytojournal.com)
This study sought to identify biomarkers for selecting patients with a high potential for developing invasive carcinoma in the breast with normal histology, benign lesions, or premalignant lesions. (cdc.gov)
A set of 26-gene mRNA expression profiles were used to identify invasive ductal carcinomas from histologically normal tissue and benign lesions and to select those with a higher potential for future cancer development (ADHC) in the breast associated with atypical ductal hyperplasia (ADH). (cdc.gov)
The expression-defined model achieved an overall accuracy of 94.05% (AUC = 0.96) in classifying invasive ductal carcinomas from histologically normal tissue and benign lesions (n = 185). (cdc.gov)

Basal or squamous cell skin cancers may need to be removed with procedures such as electrodessication and curettage, surgical excision, or Mohs surgery, with possible reconstruction of the skin and surrounding tissue. (healthyskinworld.com)
risk of basal and squamous cell skin cancer. (who.int)

According to the National Comprehensive Cancer Network (NCCN), the goal of treatment for basal cell carcinoma (BCC) is elimination of the tumor with maximal preservation of function and physical appearance. (medscape.com)

Lower female genital tract tumors with adenoid cystic differentiation are rare, and data on their relationship with highrisk human papillomavirus (HPV) are limited. (elsevierpure.com)
Lower female genital tract carcinomas with adenoid cystic differentiation appear to comprise 2 pathogenetically distinct groups. (elsevierpure.com)
Cervical carcinomas with mixed differentiation, including adenoid cystic, adenoid basal, squamous, and small cell components, are etiologically related to high-risk HPV and can be identified by diffuse p16 expression. (elsevierpure.com)
Pure vulvar and cervical adenoid cystic carcinomas appear to be unrelated to high-risk HPV and are distinguished from the mixed carcinomas by nondiffuse p16 expression. (elsevierpure.com)
Surprisingly, adenoid cystic carcinomas and basal cell adenomas were negative in 100% of the cases. (qxmd.com)
The high expression of CD10 by this carcinoma can be a valuable tool to separate EMEC from the tubular variant of adenoid cystic carcinomas in small incisional biopsies, where the precise diagnosis may be impossible. (qxmd.com)

Go to Renal Cell Carcinoma and Clear Cell Renal Cell Carcinoma for more complete information on these topics. (medscape.com)

CK5 is a type II CK (high molecular weight, 62 kDa) expressed in the basal and myoepithelial cells of various epithelia and glandular structures including the bronchi, prostate and breast. (roche.com)
[ 7 ] Knowledge of preceding treatment and the finding of other therapy-related changes, such as glandular atrophy, as well as basal cell hyperplasia, should alert to this differential. (medscape.com)

Immunohistochemical comparison of cutaneous lymphadenoma, trichoblastoma, and basal cell carcinoma: support for classification of lymphadenoma as a variant of trichoblastoma. (asocolderma.org.co)
An immunohistochemical study of basal cell carcinoma and trichoepithelioma. (asocolderma.org.co)
[ 7 ] Tumors with pure sarcomatoid morphology due to overgrowth of the RCC components are classified as SRCC if evidence of epithelial differentiation can be demonstrated through immunohistochemical or ultrastructural analysis. (medscape.com)
Language": "en", "Country": "XG", "Code": "Storage Conditions (Product)" }, { "Name": "Intended Use", "Value": "Anti-Cytokeratin 5/6 (D5/16B4) Mouse Monoclonal Primary Antibody is intended for laboratory use in the qualitative immunohistochemical detection of cytokeratin 5 by light microscopy in sections of formalin-fixed, paraffin-embedded tissue stained on a BenchMark IHC/ISH instrument. (roche.com)
Tumor cells usually retain prostatic epithelial antigenicity, and immunohistochemical stains can be used for their identification. (medscape.com)

18. Mahmoodi M, Asad H, Salim S, Kantor G, Minimo C. Anticytokeratin 20 staining of Merkel cells helps differentiate basaloid proliferations overlying dermatofibromas from basal cell carcinoma. (asocolderma.org.co)
It was composed of basaloid cells, arranged in a palisading pattern around, and exhibited no significant contraction gap. (oatext.com)
The etiological classification of squamous cell carcinoma of the vulva includes at least two groups: the smaller - basaloid and warty tumors induced by human papillomaviruses (HPV), and the larger - squamous cell carcinoma, the etiology of which is unknown. (med-blog.com)
The cells are small, basaloid, vacuolated with eosinophilic cytoplasm. (constiintaortodoxa.ro)

The clinical differential diagnosis included squamous cell carcinoma, basal cell carcinoma with sebaceous differentiation, and salivary gland neoplasms. (biomedcentral.com)
CD10 (Neutral Endopeptidase) Expression in Myoepithelial Cells of Salivary Neoplasms. (qxmd.com)
In salivary glands, expression of CD10 has only been used to identify neoplastic myoepithelial cells of pleomorphic adenomas and myoepithelial carcinomas. (qxmd.com)
In salivary glands, CD10 expression was not detected in myoepithelial cells. (qxmd.com)
In conclusion, salivary neoplastic myoepithelial cells gain CD10 expression in relation to their normal counterparts. (qxmd.com)

A huge majority of cutaneous squamous cell carcinoma cases result from chronic UV exposure. (healthyskinworld.com)

Indeed apoptosis is inhibited in senescent cells. (globale-dermatologie.com)
It has been shown to induce apoptosis in both colorectal adenoma- and carcinoma-derived cell lines and in skin basal cell carcinomas. (lclabs.com)
Hedgehog signalling in colorectal tumour cells: induction of apoptosis with cyclopamine treatment. (lclabs.com)
Tabs, S., and Avci, O. "Induction of the differentiation and apoptosis of tumor cells in vivo with efficiency and selectivity. (lclabs.com)

Clinical records of 39 patients were retrieved and analyzed for gender, age, site, neoplastic type and histologic differentiation. (bvsalud.org)

Squamous cell carcinoma in situ overlying dermatofibroma. (asocolderma.org.co)
Most of the early esophageal squamous cell carcinoma in situ or early invasive carcinoma, according to the endoscopic findings can be divided into 3. (cancerlive.net)
1) well differentiated carcinoma in situ. (cancerlive.net)
2) poor differentiation of carcinoma in situ. (cancerlive.net)
The degree of differentiation of carcinoma in situ, even in the same specimens can be seen in the same field of vision. (cancerlive.net)
mucosal carcinoma in situ or invasive means of most Fu cancer cells of esophageal carcinoma in situ group, a breakthrough was cord-like basement membrane or mass, down to students up to the inherent invasive membrane or muscularis mucosa but not through the muscularis mucosa. (cancerlive.net)
Carcinoma in situ of the basement membrane break down the cell population through the muscularis mucosa into the submucosa, but not involving the muscle, and no regional lymph node metastasis. (cancerlive.net)
Development from early invasive carcinoma in situ, the tumor infiltrating the basement membrane was often exceeded in many invasive growth. (cancerlive.net)
Stage 0 Also known as carcinoma in situ, this stage is not considered to be invasive. (healthyskinworld.com)

Focal spindling due to noncohesion of tumor cells is not considered to represent sarcomatoid differentiation. (medscape.com)
If prostate biopsies are performed following hormonal therapy for prostatic adenocarcinoma, the appearance of residual tumor cells can mimic xanthoma cells. (medscape.com)

Merkel cells and sclerosing epithelial neoplasms. (asocolderma.org.co)
Glial brain tumours originating from glial cells are intracranial solid neoplasms. (hindawi.com)
It seems that these intraoral sebaceous glands can rarely give rise to a variety of sebaceous neoplasms, such as sebaceous carcinoma [ 7 ]. (biomedcentral.com)
CK5 is expressed in prostatic basal cells and the loss of CK5 expression is indicative of neoplasms that have breached the basal membrane. (roche.com)

DR+ epidermal macrophage induction, and noma in young women: An evaluation of the Langerhans cell depletion. (who.int)

We present the case of a 75-year-old woman with a history of basal cell carcinoma and actinic keratoses who presented with an asymptomatic papular lesion on her forehead that had been growing progressively for several weeks and was clinically suggestive of basal cell carcinoma ( Fig. 1 A). The lesion was excised. (actasdermo.org)
[ 5 , 7 ] indicating that even small amounts of sarcomatoid differentiation may be clinically relevant and should be included in the pathology report. (medscape.com)

High molecular weight cytokeratin (1/68kD, 19/56,6 kD) was replaced by simple cytokeratin (8/52kD, 18/45kD) which is found in neoplasic cells. (globale-dermatologie.com)
Let us underline nevertheless that such cytokeratin expression is found in embryonic cell lines and that the study only concerned 10 specimens. (globale-dermatologie.com)
On immunohistochemistry (IHC), epithelial cells showed immunoreactivity to cytokeratin 7 and epithelial membrane antigen (EMA), with Ki-67 of 10%-12%, and myoepithelial cells were highlighted by S-100 and smooth muscle actin (SMA) [Figure 1]. (ijhnp.org)
Language": "en", "Country": "XG", "Code": "Intended Use" }, { "Name": "Content", "Value": "Anti-Cytokeratin 5/6 (D5/16B4) antibody contains sufficient reagent or 50 tests. (roche.com)
Anti-Cytokeratin 5/6 (D5/16B4) antibody is a monoclonal antibody produced as cell culture supernatant. (roche.com)
Language": "en", "Country": "XG", "Code": "Content" }, { "Name": "Background Information", "Value": "Anti-Cytokeratin 5/6 (D5/16B4) Mouse Monoclonal Primary Antibody (anti-Cytokeratin 5/6 (D5/16B4) antibody) is a mouse monoclonal antibody raised for the detection of cytokeratin (CK) 5. (roche.com)

Fourteen years after the diagnosis of syringomatous carcinoma, the patient presented for surgery to improve cosmesis and relieve breathing obstruction. (appliedradiationoncology.com)
Based on these findings, a diagnosis of sebaceous carcinoma of the lower lip was rendered. (biomedcentral.com)
2. Ulrich M, Braunmuehl T, Kurzen H, Dirschka T, Kellner C, Sattler EC, Berking C, Welzel J, Reinhold U. The sensitivity and specificity of optical coherence tomography for the assisted diagnosis of nonpigmented basal cell carcinoma: an observational study. (vivosight.com)
Patient-driven management using same-day noninvasive diagnosis and complete laser treatment of basal cell carcinomas: a pilot study. (vivosight.com)

It modulates keratinocyte differentiation. (medscape.com)
Analysis of enriched pathways showed a shared increase in keratinocyte differentiation, and a decrease in cell adhesion and actin organization pathways in Darier, Hailey-Hailey, and Grover diseases. (bvsalud.org)

Originally described by Headington in the 1970s, trichoblastoma (TBL) is now appreciated as a rare benign tumor that originates from the follicular germ cell line [1, 2]. (karger.com)
The slow, benign evolution theory of this tumour is correlated with mucine production which is linked to its high celular differentiation grade. (constiintaortodoxa.ro)
1,8 The detection of CK5 in basal cells is a feature of normal and benign prostatic processes and the absence of CK5 is indicative of prostate adenocarcinoma. (roche.com)
Additionally, CK5 is expressed in myoepithelial cells (MECs) in normal breast tissue and benign processes. (roche.com)
Other patterns include arrangement of the histiocytes in cords or single cells that percolate between benign prostatic glands. (medscape.com)

4] Syringocystadenoma papilliferum, formerly known as nevus syringocystadenomatous papilliferus, is a proliferating tumor with mostly apocrine differentiation but eccrine differentiation can also be seen. (ijcrr.com)

Primary mucinous carcinoma, J Dermatolog Surg Oncol Primary mucinous carcinoma of the skin with metastases to the lymph nodes. (constiintaortodoxa.ro)

Esophageal carcinoma is the third most common gastrointestinal malignancy worldwide and is largely unresponsive to therapy. (biomedcentral.com)
To begin to define genetic alterations that occur in African-American ESCC we conducted microarray expression profiling in pairs of esophageal squamous cell tumors and matched control tissues. (biomedcentral.com)
Loss of activity of drug metabolizing enzymes would confer increased sensitivity of esophageal cells to xenobiotics, such as alcohol and tobacco smoke, and may account for the high incidence and aggressiveness of ESCC in this ethnic group. (biomedcentral.com)
Adenocarcinoma of the esophagus (EAC) is mostly seen in Western countries [ 3 ] while esophageal squamous cell carcinoma (ESCC) is predominant in Eastern countries and the eastern part of Africa [ 3 ]. (biomedcentral.com)

A number of skin tumors show differentiation toward hair matrix components, including Gardner syndrome cysts, basal cell carcinoma, purely matrical tumors (pilomatricoma, matricoma, melanocytic matricoma, and pilomatrix carcinoma), and even some mixed tumors. (actasdermo.org)

Photodynamic therapy (PDT) for basal cell carcinomas is the process of using specific wavelengths of light to photoexcite porphyrins that have been applied to neoplastic and preneoplastic cells. (medscape.com)
Neoplastic cells showed a range of sebaceous differentiation with finely vacuolated rather than clear cytoplasm. (biomedcentral.com)
Neoplastic cells were positive for S-100 protein and epithelial membrane antigen, but negative for carcinoembryonic antigen. (biomedcentral.com)
CD10 is a cell surface peptidase expressed in a wide variety of normal and neoplastic tissues, including breast myoepithelial cells. (qxmd.com)

An MC3T3-E1-based microarray dataset (accessioned as GSE46400) downloaded from the Gene Expression Omnibus included MC3T3-E1 cells with or without 14-day osteoblast differentiation osteoblast induction. (frontiersin.org)

In pilot studies, CRL evaluated the antitumor effects of immune checkpoint inhibitors (CPIs) on colon epithelial carcinoma (RKO) and basal lung cell adenocarcinoma (A549) cell lines in the HuCD34-NCG model and showed significant immunomodulatory antitumor response. (genengnews.com)
PCMC cells remain positive for CK 7 and negative for CK 20, the same occurs for the mucinous adenocarcinoma of the breast, but in the case of the mucinous colorectal adenocarcinoma CK 7 is negative and CK 20 is positive. (constiintaortodoxa.ro)

When the different groups of tumors were compared, epithelial-myoepithelial carcinomas (EMEC) showed a stark contrast with the others (83.3% of cases with CD10 expression). (qxmd.com)
However, the gain of this protein is not a sensitive marker for detecting myoepithelial cells in the majority of the tumors, except for EMEC. (qxmd.com)
13-15 Several MEC markers exist and recommendations include use of IHC studies for at least two markers to demonstrate the presence or absence of myoepithelial cells. (roche.com)

Sebaceous carcinoma (SC) is a rare neoplasm. (biomedcentral.com)

Radiation-induced syringomatous carcinoma of the left nose. (appliedradiationoncology.com)
Although radiation-induced MAC has been reported, there are no previous reports of radiation-induced syringomatous carcinoma. (appliedradiationoncology.com)
This report presents a unique case of likely radiation-induced syringomatous carcinoma in a patient previously treated with radiation for a left intranasal squamous cell carcinoma. (appliedradiationoncology.com)

Tan II A reduced CXCL12-induced A375 cell invasive ability and migration in a dose dependent manner. (biomedcentral.com)
The invasive and migratory capabilities of tumour cells were tested with the transwell and wound healing assays, respectively. (jcancer.org)

Basal cell carcinoma (BCC) is a nonmelanocytic skin cancer (ie, an epithelial tumor) that arises from basal cells (ie, small, round cells found in the lower layer of the epidermis). (medscape.com)
Basal cell carcinoma (BCC), which arises from the basal cells in the epidermis, is the most common form of skin cancer. (e-acfs.org)

To determine the precise origin of SCC, ASPP2 will be deleted in keratin 14-positive basal cells and keratin 1-positive suprabasal cells using keratin 14-Cre or keratin 1-Cre respectively. (ukri.org)
Expression of Notch1 , Jagged1 , and Hes1 was found predominantly in the basal and immediate suprabasal cells. (molvis.org)

Full-thickness epithelial cancer cells, cancer cells vary in size, or were pleomorphic, disordered polar disappear. (cancerlive.net)

Foamy gland carcinoma of the prostate features cells with abundant finely vacuolated cytoplasm and pyknotic hyperchromatic nuclei. (medscape.com)

While it is possible that SCCs initially develop in basal cells, it is unclear why such basal cells in SCCs begin to express differentiation markers. (ukri.org)
This seems not to be a problem with the THIN database itself, but attributable to the Read coding scheme being, in practice, unable to allow differentiation between SCCs of different organs. (nih.gov)

We tested the effects of Tan II A on melanoma A375, MV3, M14, and other human cell lines including Hacat and HUVEC cells in cell culture model. (biomedcentral.com)
Cell migration ability melanoma A375 was monitored by using cell scratch assay. (biomedcentral.com)
Transwell chamber experimental was performed to assess the effect of Tan II A on A375 melanoma cell invasion ability. (biomedcentral.com)

This agent is indicated for treatment of adults with metastatic basal cell carcinoma or with locally advanced basal cell carcinoma that has recurred following surgery, or those who are not candidates for surgery or radiation. (medscape.com)
The primary source of metastatic tumors is more oftentotal is squamous cell carcinoma of the cervix, then - cancer of the endometrium, bladder and urethra. (med-blog.com)

Sebaceous carcinoma in the oral cavity is extremely rare, with only 14 cases reported in literature. (biomedcentral.com)
Sebaceous carcinoma should be distinguished from other tumors full of vacuolated clear cells. (biomedcentral.com)
While several reports document sebaceous adenomas arising from sebaceous glands of the oral cavity, oral sebaceous carcinomas are extremely rare. (biomedcentral.com)

Our preliminary results show that the tumour suppressor ASPP2 is able to repress p63 expression, is highly expressed in keratin 1-positive and keratin 14-negative stratified epithelial cells, and that differentiation induces ASPP2's expression in vitro. (ukri.org)
According to classification system of the World Health Organisation (WHO) based on histological evaluation, brain tumour grade is determined by necrotic cells in the centre of the tumour, increased mitotic activity, the presence of nuclear pleomorphism, and angiogenesis. (hindawi.com)
Matrix metalloproteinase-7 (MMP-7) facilitates degradation of the extracellular matrix, promoting the invasion of tumour cells, and is associated with cancer progression and metastasis. (jcancer.org)
In previous reports, we identified a set of genes regulated by Hh signalling in ovarian tumour cells among which MMP-7 was identified as a potential Hh target gene candidate. (jcancer.org)
MMP-7 facilitated the invasion and migration of ovarian tumour cells, indicating its key function in ovarian cancer progression. (jcancer.org)

17. Cheng L, Amini SB, Tarif Zaim M. Follicular basal cell hyperplasia overlying dermatofibroma. (asocolderma.org.co)

SCC cells may instead be derived from differentiated keratin 1-positive cells in the suprabasal layer. (ukri.org)
On July 28, 2021, extended 5mm resection (depth up to subcutaneous fat layer and nasal cartilage) of nasal basal cell carcinoma and full-thickness skin graft repair (medial skin graft of the left upper arm) were performed under local anesthesia (Figure 2). (oatext.com)
Although the whole layer of epithelial cells in cancerous, but some of the more mature cells, cells large, were polygonal or round, large cytoplasm, nuclear round, small. (cancerlive.net)
Sometimes the nuclear vacuolization, the more the more obvious near-surface, while the cancer cells near the basal layer, the mostly undifferentiated basal cells. (cancerlive.net)
Layer of epithelial cells in all disorder, normal levels disappear, the cancer cells more consistent shape, cell size is small, oval or spindle-shaped nucleus often has, nuclear large and small, dark staining, mitotic common, but the basement membrane integrity. (cancerlive.net)
The abnormal cells are only in the upper layer of the epidermis, the outer skin. (healthyskinworld.com)

Carcinoma cervix is not the only cancer caused by HPV. (cytojournal.com)

While these diseases have different underlying causes, they share defects in cell-cell adhesion in the epidermis and desmosome organization. (bvsalud.org)

Porocarcinoma (PC) and basal cell carcinoma (BCC) are distinct skin cancers. (e-acfs.org)
their evolution from distinct cell lineages. (lu.se)

Anatomy33

Organisms5

Diseases72

Chemicals and Drugs65

Analytical, Diagnostic and Therapeutic Techniques and Equipment37

Phenomena and Processes41

Disciplines and Occupations2

Information Science4

Health Care7

Desmoplastic trichoepithelioma10

Infiltrative4

Malignant18

Proliferation16

Adnexal carcinoma6

Tumors with myoepithelial differentiation2

Biopsy5

Types of basal2

Small cell carc1

Epithelium7

Subtype3

Seborrheic keratosis2

Superficial basal2

Subtypes3

Lesions7

Squamous cell skin2

Treatment for basal1

Adenoid6

Renal Cell Carc1

Glandular2

Immunohistochemical5

Basaloid4

Salivary5

Cutaneous squamous1

Apoptosis4

Histologic differentiation1

Situ9

Tumor cells2

Neoplasms4

Epidermal1

Clinically2

Cytokeratin6

Diagnosis4

Keratinocyte2

Benign5

Nevus1

Surg1

Esophageal4

Cysts1

Neoplastic4

Gene Expression1

Adenocarcinoma2

Myoepithelial3

Rare neoplasm1

Radiation-induced3

Invasive2

Arises2

Suprabasal cells2

Epithelial cancer1

Finely vacuolated1

SCCs2

Melanoma3

Metastatic2

Sebaceous3

Tumour5

Hyperplasia1

Layer6

Cervix1

Epidermis1

Distinct2