• The active ingredient in most decongestants is either pseudoephedrine or phenylephrine (the latter of which has disputed effectiveness). (wikipedia.org)
  • These coated tablets contain the decongestant ingredient phenylephrine along with the pain reliever ibuprofen. (healthline.com)
  • Phenylephrine, a popular ingredient found in many over-the-counter cold medicines, is an ineffective decongestant when taken orally and works no better than a placebo, an independent advisory committee to the U.S. Food and Drug Administration said Tuesday. (yahoo.com)
  • This comes after the 16-member panel with the FDA said that a commonly used dose of the decongestant phenylephrine doesn't work. (klfy.com)
  • Phenylephrine became the main drug in over-the-counter decongestants when medicines with an older ingredient, pseudoephedrine, were moved behind pharmacy counters. (klfy.com)
  • Some types of over-the-counter decongestants, including the popular phenylephrine and pseudoephedrine have been linked to rare, specific birth defects of the digestive tract, ear and heart. (madeformums.com)
  • An FDA panel just officially decreed that the decongestant phenylephrine found in many over-the-counter cold medications doesn't work. (wvpe.org)
  • Going back to 2015, there was a citizen's petition to remove phenylephrine from the over-the-counter drugs in the U.S. Back then, researchers had studies showing that as an oral decongestant, it's completely ineffective. (krvs.org)
  • The FDA assembled its outside advisers to take another look at phenylephrine, which became the main drug in over-the-counter decongestants when medicines with an older ingredient - pseudoephedrine - were moved behind pharmacy counters. (cp24.com)
  • Have you ever suffered from a cold or allergies, reached for medication, and well, it doesn't work?Phenylephrine, acommon ingredient in many over-the-counter decongestant medications, may not be doing anything for your stuffy nose. (kalw.org)
  • The committee's ruling could prompt the FDA to pull all oral decongestants containing phenylephrine from store shelves, leaving cold sufferers with limited options to relieve their misery. (pollen.com)
  • Medications with phenylephrine took on more prominence after the highly effective decongestant pseudoephedrine became harder to purchase in 2005, as part of legislation aimed at combatting the meth epidemic. (pollen.com)
  • Ever since pseudoephedrine went 'behind the counter' in the 2000s, phenylephrine became one of the most commonly available and widely used decongestants," said Dr. William Fox , an internal medicine doctor in Charlottesville, Va. (pollen.com)
  • Therefore, in addition to lack of efficacy, there may be no path to evaluating higher doses of oral phenylephrine as a nasal decongestant," the FDA concluded. (pollen.com)
  • In 1976, the FA evaluated the safety and effectiveness of oral decongestants including phenylpropanolamine (PPO), pseudoephedrine (PSE) and phenylephrine (PE). (blufftonicon.com)
  • The change in status for PSE and PPO resulted in phenylephrine being the only oral decongestant available for over-the-counter cold, flu, and allergy products. (blufftonicon.com)
  • An FDA panel recently declared that the over-the-counter decongestant phenylephrine does not work. (milberg.com)
  • That's the damning conclusion of a Food and Drug Administration (FDA) panel about phenylephrine decongestants, whose efficacy have been questioned since they were introduced in the early 2000s. (milberg.com)
  • Phenylephrine was approved by the FDA for over-the-counter use in 1976 and became the main ingredient in OTC decongestants in 2006. (milberg.com)
  • Fast-forward to the second phenylephrine FDA advisory committee in 2023, where a panel voted 16-0 that the oral decongestant is clinically ineffective in reducing congestion symptoms. (milberg.com)
  • Nonetheless, the complaint continues, CVS represents its PE products as "MAXIMUM STRENGTH," which is misleading to consumers because phenylephrine is ineffective, and products with effective nasal decongestants, including those containing pseudoephedrine, are available. (milberg.com)
  • The Food and Drug Administration's independent Nonprescription Drugs Advisory Committee Sept. 12 by unanimous vote declared oral phenylephrine ineffective as a decongestant. (industryintel.com)
  • FILE - Sudafed and other common nasal decongestants containing pseudoephedrine display behind the counter at a pharmacy. (komonews.com)
  • They may not like using alternative nasal sprays, or know how to obtain the decongestant pseudoephedrine, which is sold behind the counter in pharmacies due to its misuse as an ingredient to make methamphetamine. (yahoo.com)
  • Sudafed and other common nasal decongestants containing pseudoephedrine are on display behind the counter at Hospital Discount Pharmacy in Edmond, Okla., Jan. 11, 2005. (wvpe.org)
  • Each tablet contains 240 mg of pseudoephedrine HCl, a nasal decongestant for powerful 24-hour symptom relief. (sudafed.com)
  • Each tablet contains 240 mg of pseudoephedrine HCl, a nasal decongestant, and relieves symptoms for up to 24 hours. (sudafed.com)
  • Pseudoephedrine was previously the oral decongestant of choice for drug manufacturers. (milberg.com)
  • Intranasal corticosteroids can also be used as decongestants and antihistamines can be used to alleviate runny nose, nasal itch, and sneezing. (wikipedia.org)
  • Topical nasal decongestants, oral decongestants, nasal steroids, and antihistamines can be used to treat ETD. (medscape.com)
  • Although combination formulas containing antihistamines, decongestants, and/or analgesics are sold over the counter in large quantities for the common cold, the evidence of effectiveness is limited. (aafp.org)
  • Tried antihistamines and decongestants with little to no avail. (healthtap.com)
  • They wrote: 'A small number of trials report contradictory results for decongestants and antihistamines on nasal symptoms and safety in children. (lincolnshirelive.co.uk)
  • Some antihistamines include decongestants, which can reduce congestion, but those medicines are not for everyone. (medlineplus.gov)
  • A decongestant, or nasal decongestant, is a type of pharmaceutical drug that is used to relieve nasal congestion in the upper respiratory tract. (wikipedia.org)
  • Decongestants are used to treat nasal congestion, for instance in allergies, infections like the common cold, influenza, and sinus infection, and nasal polyps. (wikipedia.org)
  • Decongestants help to relieve stuffy nose and ear congestion symptoms.If you are self-treating with this medication, carefully read the package instructions to be sure it is right for you before you start using this product. (webmd.com)
  • https://www.medshopexpress.com/nexafed-nasal-decongestant-30-mg-tablets-24-tab For the temporary relief of nasal congestion due to the common cold, hay fever or other upper respiratory allergies. (medshopexpress.com)
  • Maximum strength decongestant provides all-day relief from sinus congestion & pressure. (sudafed.com)
  • Is nasal congestion w/ decongestant stick a concern? (healthtap.com)
  • Patients were also warned not to take decongestants for longer than advised as long term use can actually lead to chronic nasal congestion. (lincolnshirelive.co.uk)
  • Are over-the-counter antihistamine/decongestant/analgesic combinations effective in alleviating the symptoms and reducing the duration of the common cold in adults and children? (aafp.org)
  • Combination cold medications, including antihistamine/decongestant/analgesic, antihistamine/decongestant, antihistamine/analgesic, and analgesic/decongestant formulations, provide modest symptom relief in adults and older children, but are not effective in young children. (aafp.org)
  • To assess the effectiveness of antihistamine/decongestant/ analgesic combinations in reducing the duration and alleviating the symptoms of the common cold in adults and children. (aafp.org)
  • Randomized controlled trials investigating the effectiveness of antihistamine/decongestant/analgesic combinations compared with placebo, other active treatments (excluding antibiotics), or no treatment in children and adults with the common cold. (aafp.org)
  • and five, antihistamine/decongestant/ analgesic combinations. (aafp.org)
  • I do know very conclusively that nasal spray works better than any antihistamine or oral decongestant for helping a congested nose," Prather said. (klfy.com)
  • Buckley's DM Decongestant consists of multiple generic medications. (rxwiki.com)
  • Other than over-the-counter (OTC) decongestants, he is taking no medications. (cdc.gov)
  • Something as innocent as a decongestant can be deadly in combination with other medications. (cdc.gov)
  • Ergotamine , selective serotonin reuptake inhibitors, α-sympathomimetic decongestants, and triptans are among the medications implicated in cases of the syndrome. (medscape.com)
  • The leading decongestant used by millions of Americans looking for relief from a stuffy nose is likely no better than a dummy pill, according to government experts who reviewed the latest research on the long-questioned drug ingredient. (komonews.com)
  • The risk of an endocardial cushion defect among babies whose mothers did not take decongestants is about 3 per 10,000 live births. (madeformums.com)
  • Mitchell believes there's enough evidence indicating a possible connection to birth defects that doctors should not be recommending that pregnant women take decongestants, but should evaluate each woman's need for the drugs on a case-by-case basis. (madeformums.com)
  • Decongestant nasal sprays and eye drops often contain oxymetazoline and are used for topical decongestion. (wikipedia.org)
  • Use of imidazolines (found in nasal decongestant sprays and eye drops) was tied to an approximate doubling of risk for an abnormal connection between the trachea and oesophagus. (madeformums.com)
  • Don't use decongestant nasal sprays, drops, or gels more times in one day or for more days in a row than the label says. (uofmhealth.org)
  • Decongestants can be absorbed from the nose via an inhaler and produce systemic effects, mainly central nervous system stimulation and rise in blood pressure. (wikipedia.org)
  • Oral decongestants may cause more side effects than the ones used in the nose, but they can be taken for up to 7 days. (uofmhealth.org)
  • Decongestants may help shrink swollen tissues in the nose, sinuses, and throat and in the space behind the eardrum (middle ear). (uofmhealth.org)
  • Nose sprays/steam/decongestants no help. (healthtap.com)
  • The authors also issued advice for adults, saying they could try nasal decongestants for three to seven days if a blocked or runny nose, or sneezing related to a cold is bothersome. (lincolnshirelive.co.uk)
  • Decongestants may also interact with some drugs, such as certain antidepressants and high blood pressure medicines. (uofmhealth.org)
  • But he says the markets would adjust, and the good news is that there are other over-the-counter medicines that are effective as nasal decongestants, including nasal sprays, so people would have alternative options, A. (krvs.org)
  • Those original versions of Sudafed and other medicines remain available without a prescription, but they're less popular and account for about one-fifth of the $2.2 billion market for oral decongestants. (cp24.com)
  • You should not use this medicine if you have ever had an allergic reaction to a decongestant or pain medicine. (adam.com)
  • If you are pregnant or breastfeeding, check with your doctor or pharmacist before you use a decongestant. (uofmhealth.org)
  • Care Decongestant tablets contain the same ingredient that you will find in Sudafed products. (travelpharm.com)
  • The Food and Drug Administration said on Tuesday that nasal decongestants like Dayquil and Allegra don't work the way they're intended to. (kztv10.com)
  • The decongestant in your favorite OTC medication doesn't work any better than a placebo. (milberg.com)
  • In this paper , the number of treatments of different types of concomitant medication ( antibiotics , nasal decongestants and others) was used as a basis for statistical comparisons between the different test groups. (bvsalud.org)
  • Read the package carefully or ask your pharmacist or doctor to help you choose the best decongestant for you. (uofmhealth.org)
  • Decongestants (Talk to your pharmacist about the kind you should buy. (cdc.gov)
  • Xzantrol by HPI is specially formulated nasal flush and decongestant for horses that suffer from respiratory issues and performance horses. (bigdweb.com)
  • Decongestants can cause problems for people who have certain health problems, such as heart disease, high blood pressure, glaucoma, diabetes, or an overactive thyroid. (uofmhealth.org)
  • Lead plaintiff Rhonda Nitto purchased CVS PE products believing them, based on their labeling, to have the strongest decongestant and maximum acetaminophen dosage allowable without a prescription. (milberg.com)
  • Topical decongestants on topical application as dilute solution (0.05-0.1%) produce local vasoconstriction. (wikipedia.org)
  • Topical nasal or ophthalmic decongestants quickly develop tachyphylaxis (a rapid decrease in the response to a drug after repeated doses over a short period of time). (wikipedia.org)
  • Decongestant ingredients work by dilating your blood vessels to relieve pressure in your sinuses. (healthline.com)
  • Decongestants and nasal spray don't work. (healthtap.com)
  • How well did Buckley's DM Decongestant work for you? (rxwiki.com)
  • If you're having trouble breathing due to cold, flu, or allergies, sinus decongestants are designed to relieve your symptoms and help you carry on with your day. (healthline.com)
  • Only the analgesic/ decongestant formulation is associated with a statistically significant increased risk of adverse effects. (aafp.org)
  • Over-the-counter (OTC) sinus decongestants may be able to offer temporary relief from your symptoms. (healthline.com)
  • Some products that contain decongestant may improve nasal symptoms in children, but their safety, especially in young children, is unclear. (lincolnshirelive.co.uk)
  • If your child has a cold do not give them decongestants, medical experts are warning. (lincolnshirelive.co.uk)
  • However, decongestants are some of the most commonly used drugs so it's important to understand the consequences of taking them during pregnancy, said Mitchell, director of the Slone Epidemiology Center at Boston University. (madeformums.com)
  • CVS decongestant PE products are also mislabeled as "MAXIMUM STRENGTH" for a second reason, the lawsuit alleges. (milberg.com)
  • Since the absolute risks for these rare birth defects are still very small, pregnant women should not be very worried after having used these drugs,' said Marleen van Gelder, an epidemiologist at Radboud University Nijmegen Medical Center in the Netherlands who was not involved in the study but has researched birth defects and decongestants before. (madeformums.com)
  • This recipe make 17 small Decongestant Shower Melts. (hometalk.com)
  • The authors added: 'Do not prescribe decongestants to children under 12 , as evidence of their effectiveness is limited and associated risks may exist. (lincolnshirelive.co.uk)