• The majority of each stakeholder group considered validated electronic methods moderately or extremely useful to re-consent previously enrolled research participants upon study amendments or to obtain consent from COVID-19 patients. (frontiersin.org)
  • This study provides data on the comparison of the two most clinically relevant body composition methods in pediatric obese patients. (biomedcentral.com)
  • Most of these methods either expose the patient to radiation, are time consuming, inconvenient and expensive. (biomedcentral.com)
  • Patients declining randomization will be asked to enroll into an observational cohort with same outcomes and post-treatment regimes. (researchsquare.com)
  • Empowering patients to participate in nutrition care during hospitalisation may improve their dietary intakes and associated outcomes. (mdpi.com)
  • Additionally, the study will provide information on long-term adherence, changes in motor symptoms, cognitive functions and patient-reported outcomes after the rehabilitation program. (frontiersin.org)
  • Findings to date Detailed clinical and laboratory data in high granularity as well as patient-reported outcomes from transplant recipients and activities in Switzerland are available in the last decade. (bmj.com)
  • Secondary outcomes include the percentage of severe flare, the percentage of mild-to-moderate flare, time to first disease flare, changes in prednisone dose, SELENA-SLEDAI, as well as BILAG score, the percentage of patients achieving prednisone free and safety analysis. (bmj.com)
  • Critical inhaler handling errors are associated with an increased risk of adverse outcomes in patients with chronic obstructive pulmonary disease (COPD). (dovepress.com)
  • modify the patient's beliefs and consider patient's characteristics (21/25 statements) to influence patient outcomes during chronic LBP rehabilitation. (biomedcentral.com)
  • All five CF domains were perceived as capable of influencing patient outcomes, with the patient-practitioner relationship being perceived as the most important CF during routine clinical practice. (biomedcentral.com)
  • Although open-label observations report a positive effect of cannabinoids on non-motor symptoms (NMS) in Parkinson's disease (PD) patients, these effects remain to be investigated in a controlled trial for a broader use in NMS in PD patients. (springer.com)
  • This study will advance our understanding of ventricular remodelling in MR, its impact on patient symptoms and ventricular response following surgery. (biomedcentral.com)
  • In particular, loss of appetite and reduced interest in food are common complaints amongst depressed patients, although such symptoms are often overlooked or undermined in clinical assessments due to insufficient testing regimes 15 . (nature.com)
  • To evaluate the efficacy and tolerability of α-galactosidase in the treatment of gas-related symptoms in pediatric patients. (biomedcentral.com)
  • Fifty-two pediatric patients (32 female, age range 4-17) with chronic or recurrent gas-related symptoms were randomized to receive placebo (n = 25) or α-galactosidase (n = 27). (biomedcentral.com)
  • In thinking about the individual patient as located within a social matrix, an enriched understanding and formulation of symptoms and strengths may be reached. (bmj.com)
  • For patients with mild to moderate symptoms, instant access to digital mental health programmes allows them to feel they are making progress. (silvercloudhealth.com)
  • Interocclusal appliances are often used to treat patients with TMD with the aim of stabilizing the unstable occlusion, rearranging the function of chewing muscles, of TMJ, relieving the painful symptoms experienced by these patients 3 . (bvsalud.org)
  • There is no gold standard in body composition measurement in pediatric patients with obesity. (biomedcentral.com)
  • At clinical routine due to its feasibility, safety, and efficiency, bioelectrical impedance analysis is appropriate for obese pediatric patients. (biomedcentral.com)
  • There is a lack of knowledge of body composition in pediatric patients with obesity. (biomedcentral.com)
  • Delayed cerebral ischemia (DCI) is a common secondary complication and an important cause of disability and mortality among patients who survive aneurysmal subarachnoid hemorrhage (aSAH). (biomedcentral.com)
  • reported a lower mortality rate in septic patients who received total parenteral nutrition containing 100 ml (ml) n3-PUFAs daily for 4 weeks. (biomedcentral.com)
  • The secondary endpoints include quality of life measured by EQ-5D, mortality, complications, intracranial pressure and cerebral perfusion pressure control and incidence of salvage craniectomy in craniotomy patients at each investigation time point. (biomedcentral.com)
  • A number of TB control programmes have found high rates of initial patient default as a result, with high mortality recorded in several resource-limited settings. (bvsalud.org)
  • We aim to compare two different doses of dexamethasone in patients with moderate to severe ARDS undergoing mechanical ventilation regarding efficacy and safety. (biomedcentral.com)
  • Patients with moderate-to-severe chronic obstructive pulmonary disease (COPD) experience on average, two to three exacerbation episodes per year [ 1 , 2 ]. (ersjournals.com)
  • Patients with moderate to severe nonproliferative diabetic retinopathy (NPDR) had POBF 18% higher than the control (mean OBF, 943 μL/min). (arvojournals.org)
  • The digestive enzyme decreased the number of days with moderate to severe bloating (p = 0.03) and the proportion of patients with flatulence ( p = 0.02). (biomedcentral.com)
  • REMED is a prospective, open-label, randomised controlled trial testing the superiority of dexamethasone 20 mg (dexamethasone 20 mg on days 1-5, followed by dexamethasone 10 mg on days 6-10) vs 6 mg administered once daily intravenously for 10 days in adult patients with moderate or severe ARDS due to confirmed COVID-19. (biomedcentral.com)
  • External-testing was subsequently performed on an independent dataset (221 patients) including 207 images with ODD (96 visible and 111 buried), provided by 3 centers of the Optic Disc Drusen Studies Consortium, and 214 images of papilledema (92 mild-to-moderate and 122 severe) from a previously validated study. (medrxiv.org)
  • This is a multi-centre, prospective, cross-sectional comparison of patients prior to and 9 months following surgery for chronic severe primary degenerative MR. To establish the natural history of ECV in MR, an additional cohort of patients with asymptomatic MR who do not wish to consider early repair will be followed. (biomedcentral.com)
  • In the present study, we designed a prospective, randomized, controlled trial to clarify the effect of decompressive craniectomy in severe traumatic brain injury patients with mass lesions. (biomedcentral.com)
  • In the present study, the POBF of diabetic patients with increasingly severe retinopathy was compared with that in nondiabetic control subjects. (arvojournals.org)
  • Those patients with more severe conditions can be prioritised for in-person appointments. (silvercloudhealth.com)
  • Diabetic patients with no retinopathy or mild NPDR had OBF indistinguishable from the control (785 vs. 797 μL/min). (arvojournals.org)
  • 5 Endothelin-1 activation, another potent vasoconstrictor, is also elevated in diabetic patients with retinopathy. (arvojournals.org)
  • ABSTRACT We assessed the causes of visual impairment and blindness in 694 diabetic patients attending our eye centre in Sana'a, Yemen from 2001 to 2005 by review of their medical records. (who.int)
  • Cognitive difficulties and their impact on patients' quality of life are frequently reported by patients treated for breast cancer, who ask for support to improve these difficulties. (mdpi.com)
  • The patient-practitioner relationship was rated as the most important CF, although the panel were not entirely confident in managing a range of patients' cognitive and emotional needs. (biomedcentral.com)
  • As a result, practitioners, patients, and others must be savvier and more critical consumers of medical studies and articles they see in journals, magazines, and on the Internet. (providermagazine.com)
  • Providers, health care systems, and practitioners must understand these diverse goals and be prepared to evaluate for themselves what is in patients' best interests" and realize that they may not be getting the full picture from commercially funded studies, he says. (providermagazine.com)
  • These CFs (i.e., the patient-practitioner relationship, patient's and practitioner's beliefs/characteristics, treatment characteristics, and environment) have not been widely evaluated by musculoskeletal practitioners. (biomedcentral.com)
  • Drawing on a panel of United Kingdom practitioners' expertise, this study aimed to investigate their perceptions of CFs during the management of patients presenting with chronic low back pain (LBP). (biomedcentral.com)
  • Qualified musculoskeletal practitioners in the United Kingdom providing regular treatment for patients with chronic LBP were invited to take part. (biomedcentral.com)
  • Musculoskeletal practitioners may require further training to enhance their proficiency and confidence in applying essential psychosocial skills to address the complex needs of patients with chronic LBP. (biomedcentral.com)
  • Healthcare practitioners' views regarding the recognition and modulation of contextual factors (CFs) during routine clinical practice is important and has the potential to improve the quality and effectiveness of patient care [ 1 , 2 ]. (biomedcentral.com)
  • Digital mental health solutions like those from SilverCloud, can help plug the gap by providing relief for both patients and practitioners. (silvercloudhealth.com)
  • Participants The study included 4,508 color fundus images in 2,180 patients from 30 neuro-ophthalmology centers (19 countries) participating in the Brain and Optic Nerve Study with Artificial Intelligence (BONSAI) Group. (medrxiv.org)
  • A separate cohort of 175 patients was sequenced for the top CpG sites from the discovery analysis for a replication of the EWAS findings. (biomedcentral.com)
  • Seasonality effect was calculated as the proportion of patients experiencing an exacerbation each month. (ersjournals.com)
  • For the classification of diabetic there were 17 300 patients examined at thy and diabetic eye complications is retinopathy, the modified Airlie House the centre over this period, 694 (4%) of on the rise [6]. (who.int)
  • 3 , 4 The Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2019 management cycle recommends an assessment of inhaler technique and adherence and of non-pharmacological approaches such as pulmonary rehabilitation and patient education. (dovepress.com)
  • This study should be the basis for further evaluations of long-term efficacy and safety of the use of cannabinoids in PD patients. (springer.com)
  • OBJECTIVE -To compare the efficacy and safety profile of adding inhaled human insulin (INH) (Exubera) or glibenclamide to metformin monotherapy in patients with poorly controlled type 2 diabetes. (diabetesjournals.org)
  • This study will seek to investigate the efficacy of "Microbiota modulation of the Gut-Lung Axis" combined with chemotherapy in patients with advanced NSCLC. (biomedcentral.com)
  • Based on the theoretical basis of "intestinal and lung axis microecological adjustment", combined with traditional platinum-containing two-drug chemotherapy, the efficacy of the new therapy on patients with advanced NSCLC was observed. (biomedcentral.com)
  • However, the efficacy of low-dose belimumab for prevention of disease flares in patients with SLE with low disease activity is to be explored. (bmj.com)
  • Eligible patients were stratified by smoking status and were randomised to receive placebo, 50 μg salmeterol, 500 μg fluticasone propionate or 50/500 μg salmeterol/fluticasone propionate combination via the Diskus™/Accuhaler™ inhaler (GlaxoSmithKline, London, UK) (one inhalation twice daily) for 3 yrs. (ersjournals.com)
  • Smear microscopy may, however, be costly and inconvenient for patients, who have to make multiple visits to health facilities to submit multiple sputum specimens over several days. (bvsalud.org)
  • CONCLUSIONS -In patients with type 2 diabetes poorly controlled on metformin, adding INH or glibenclamide was similarly effective in improving glycemic control, and both were well tolerated. (diabetesjournals.org)
  • However, conjugated estrogens vaginal cream is not available in Thailand, driving patients and physicians to seek alternative treatment for GSM. (biomedcentral.com)
  • A double-blind, randomized clinical trial study was conducted on 128 critically ill patients infected with COVID-19 who were randomly assigned to the intervention (fortified formula with n3-PUFA) (n = 42) and control (n = 86) groups. (biomedcentral.com)
  • The current analysis was designed to test the impact of seasonal variation on reported exacerbations in relation to other risk factors, using data from the prospective, 3-yr Towards a Revolution in COPD Health (TORCH) study involving 6,112 patients from the northern and southern regions and the tropics [ 21 ]. (ersjournals.com)
  • COPD patients were prospectively enrolled from January 2018 to November 2019. (dovepress.com)
  • Critical inhaler errors are common among patients with COPD, regardless of their preferred inhaler device. (dovepress.com)
  • Optimal device selection considering the risk factors of inhaler misusage will improve disease control in COPD patients. (dovepress.com)
  • A total of 38 patients will have 80% power to detect a probability of 0.231 that an observation in the treatment group is less than an observation in the placebo group using a Wilcoxon rank-sum test with a 0.050 two-sided significance level assuming a true difference of 2.5 points between nabilone and placebo in the primary outcome measure and a standard deviation of the change of 2.4 points. (springer.com)
  • The outcome of non-surgical treatment is generally good, but the treatment course can be long and painful with approximately a quarter of the patients acquiring a nonunion. (researchsquare.com)
  • The purpose of the study is to compare patient reported outcome after surgical and non-surgical treatment for humeral shaft fractures. (researchsquare.com)
  • Considering this demographic difference, the importance of age in terms of patient expectations, upper limb function and patient-reported outcome measures (PROM) in humeral shaft fracture treatment is not well understood. (researchsquare.com)
  • Investigations include CMR, cardiopulmonary exercise test, stress echocardiography, signal-averaged electrocardiogram, 24-h electrocardiogram monitoring, laboratory tests and patient-reported outcome measures. (biomedcentral.com)
  • Neveretheless, significant organizational and programme changes would be required to optimize the advantages of same- day diagnosis, to ensure that laboratory results are received back at the health facility and that patients start treatment on the same day. (bvsalud.org)
  • On the basis of these findings, WHO recommends that countries that have successfully implemented current WHO policy for a two-specimen case-finding strategy consider switching to same-day diagnosis, especially in settings where patients are likely to default from the diagnostic process. (bvsalud.org)
  • Patients with a diagnosis of was performed on the case notes of all impairment and blindness [4,5]. (who.int)
  • Virtual reality (VR) has emerged as a promising treatment approach in rehabilitation for patients with multiple sclerosis (MS) due to its potential to increase patient motivation and rehabilitation adherence. (frontiersin.org)
  • One of the key features for rehabilitation adherence is patient satisfaction with the VR rehabilitation (VRR) program, and information on user satisfaction and not only effectiveness is required to systematically include VRR in routine clinical practice. (frontiersin.org)
  • This program has been specifically designed for MS patients by a multidisciplinary team of specialists, based on an effective conventional rehabilitation (CR) program. (frontiersin.org)
  • Patients will attend twice weekly rehabilitation sessions on site during 4 weeks, and they will continue with rehabilitation at home for five additional months. (frontiersin.org)
  • The results from this study will help to gather valuable knowledge on the use of rehabilitation with a new VR tool in MS patients. (frontiersin.org)
  • In this prospective single-center 6-months follow-up study, 32 and 16 MS patients will receive VRR or CR, respectively. (frontiersin.org)
  • The proposed physicians-patients' alliance could promote policies in tune with professional ethics, prevent European policies' putting industrial concerns above suffering and death, bar care financing from the ambit of international trade treaties, and foster international cooperation policies consistent with the principles that inspire the design of healthcare policies at home and so reduce international migration. (biomedcentral.com)
  • Primary surgical treatment provides consistent high union rates, but patients are exposed to the risk of complications such as infection, iatrogenic radial nerve lesion and rotator cuff injury as well as shoulder impingement(4,5). (researchsquare.com)
  • If nonunion occurs, it is not uncommon for patients to go through a prolonged treatment course up to 8 months before an additional procedure is offered(10,11). (researchsquare.com)
  • Cytotoxic chemotherapy drugs have become the main treatment in recent decades, especially in patients with NSCLC without EGFR, ALK, and ROS gene mutations. (biomedcentral.com)
  • This study explores the combination of intestinal microecological regulation and chemotherapy to provide new treatment strategies and basis for lung cancer patients. (biomedcentral.com)
  • Patients will be randomised in a 1:1 ratio into one of the two treatment arms. (biomedcentral.com)
  • The evidence strongly supports the use of agonist therapies to reduce opioid use and to retain patients in treatment, with methadone maintenance remaining the gold standard of care. (lww.com)
  • It was postulated that there were links between all three categories in etiology and also treatment, i.e., if the patient is treated for GPPPD, there might be an improvement in FSIAD and vice versa [ 6 ]. (biomedcentral.com)
  • One in 14 HIV patients are living in a humanitarian crisis and only half of them receive treatment due to being mobile. (dihad.org)
  • The huge demand for mental health treatment means staff and services are struggling to keep up, while lengthy wait times often increase the anxiety that patients feel. (silvercloudhealth.com)
  • Studies show that patients who have a long wait before treatment are less likely to attend appointments and are more likely to drop out of treatment once it starts. (silvercloudhealth.com)
  • 51 consenting patients were selected with muscular and/or joint TMD, according to the criteria of the Research Diagnostic Criteria protocol (RDC/TMD) and needing the use of an interocclusal device as part of a conservative treatment at the São Leopoldo Mandic Dental Research Center in Campinas, São Paulo, Brazil. (bvsalud.org)
  • The patients' concerns are care accessibility, quality, and price. (biomedcentral.com)
  • Secondarily, discomfort with VRR will be evaluated, and therapy adherence and changes in a variety of domains typically affected by MS will be compared between patients receiving VRR and patients receiving CR. (frontiersin.org)
  • Mental health patients are typically highly motivated when they first speak to their GP. (silvercloudhealth.com)
  • Compassion or empathy is the capacity to suffer with the patient. (biomedcentral.com)
  • Against this background, given the powerful, symbolic significance of their common voice, physicians' and patients' organisations could effectively leverage together political parties and employers' organisations to promote policies favouring access to professional care. (biomedcentral.com)
  • To provide a foundation for negotiations between physicians' and patients' organisations, we propose policy principles derived from an analysis of rights-holders and duty-bearers' stakes, i.e., patients, physicians and health professionals, and taxpayers. (biomedcentral.com)
  • Physicians need to understand that we have a moral responsibility to the patient to provide the best possible medical care and bring the best medical science. (providermagazine.com)
  • We saw use of these medications rise rapidly between 1999 and 2006, mainly because physicians were led to believe that using these drugs was in the best interest of their patients. (providermagazine.com)
  • Until real data are available in real time, physicians can't be sure they are bringing the true fruits of medical science to their patients. (providermagazine.com)
  • In patients with COVID-19 pneumonia in need of oxygen therapy or mechanical ventilation, dexamethasone 6 mg per day is currently recommended. (biomedcentral.com)
  • Even for those already progressing along the NHS patient pathway, digital mental health programmes can help support them between appointments. (silvercloudhealth.com)
  • Given that information on patient satisfaction with VRR is scarce, the primary objective of this study is to assess long-term patient satisfaction with a novel VRR program. (frontiersin.org)
  • The objective of this study was to assess the approval rating of patients with muscular and/or joint TMD during the use of an interocclusal device. (bvsalud.org)
  • This study tested the acceptability and feasibility of a technology-based intervention to engage hospital patients in nutrition care at a tertiary teaching hospital in Australia. (mdpi.com)
  • Regardless of the funding sources, there has always been a dearth of clinically specific research involving long term care facilities and patients. (providermagazine.com)
  • All were patients of the Early Psychosis Prevention and Intervention Centre (EPPIC) in Melbourne, Australia. (cambridge.org)
  • RÉSUMÉ Nous avons évalué les causes des déficiences visuelles et de la cécité chez 694 patients diabétiques ayant consulté dans notre centre des soins oculaires à Sanaa (Yémen) entre 2001 et 2005 en examinant leur dossier médical. (who.int)
  • We hypothesize that nabilone will improve NMS in patients with PD and have a favorable safety profile. (springer.com)
  • It can help prolong the survival time of lung cancer patients and improve the quality of life, thereby generating huge economic and social benefits. (biomedcentral.com)
  • The focus of debate resides in whether DC would be able to improve the prognosis of patients. (biomedcentral.com)
  • In this trial, 336 patients with traumatic mass lesions will be randomly allocated to a therapeutic decompressive craniectomy group or a prophylactic decompressive craniectomy group. (biomedcentral.com)
  • A modified two-round online Delphi-consensus survey was conducted to measure the extent of panel agreement regarding the perceived acceptability and influence of five main types of CFs during clinical management of patients with chronic LBP. (biomedcentral.com)
  • To promote a universal health system, patients' organisations should strive to represent universal health interests rather than those of patients with specific diseases, ethnic groups, or social classes. (biomedcentral.com)
  • Organization (WHO), following standards appropriate for evaluating both the accuracy and the effect of new interventions on patients and public health. (bvsalud.org)
  • According to the World Health Organization definitions, 273 (39.3%) patients had visual impairment and 109 (15.7%) were blind. (who.int)
  • Patients generally cope better with their illness as a result. (bmj.com)
  • To investigate the role of DNA methylation in DCI risk, we conducted an epigenome-wide association study (EWAS) in 68 patients followed up to 1 year after the initial aneurysm rupture. (biomedcentral.com)
  • Patients face a great risk of harm from this research. (providermagazine.com)
  • The rates and risk factors for critical inhaler errors differed among patients using different devices. (dovepress.com)
  • We observed 825,239 PrEP prescriptions, a 22.0% reduction (95% CI: 19.1%-24.8%) after the emergency declaration. (cdc.gov)
  • Acceptability was assessed using patient satisfaction and engagement surveys. (mdpi.com)
  • The study is intended to provide a better understanding of long-term patient satisfaction with a VRR program specifically designed for MS patients. (frontiersin.org)
  • Patient satisfaction. (bvsalud.org)
  • This paper aimed to examine the effect of n3-PUFA supplementation on inflammatory and biochemical markers in critically ill patients with COVID-19. (biomedcentral.com)
  • Patients with medical records covering 1 year for the 1-h pad test, who completed the International Consultation on Incontinence Questionnaire-Short Form (ICIQ-SF) and the Overactive Bladder Symptom Score (OABSS), were included. (springer.com)
  • According to the Declaration of Helsinki, voluntary consent of participants, having the capacity of providing IC, must be obtained prior to their inclusion in medical research ( 5 ). (frontiersin.org)
  • Delayed cerebral ischemia (DCI) is a common secondary complication among aneurysmal subarachnoid hemorrhage (aSAH) patients who survived the initial bleeding caused by ruptured aneurysm. (biomedcentral.com)
  • Salvage decompressive craniectomy will be performed for craniotomy patients once there is evidence of imaging deterioration and post-operative malignant intracranial hypertension. (biomedcentral.com)
  • Patients undergoing surgery will have cardiac biopsies performed at the time of mitral valve repair for histological quantification of fibrosis. (biomedcentral.com)
  • The disease is associated with a high economic burden for society, and Spain is the European country with the highest total annual cost per patient ( 3 , 4 ). (frontiersin.org)
  • In line with their obligations defined in the Universal Declaration of Human Rights, CEDAW, as well as the International Covenant on Economic, Social and Cultural Rights, States must pro-actively engage in activities intended to strengthen people's -including women informal workers'- access to and utilization of resources and means to ensure their livelihood, including food security, social security, and employment even in times of pandemics or natural or other disasters. (lu.se)