Dicarbonyl/L-xylulose reductase, also known as carbonyl reductase II, is an enzyme that in human is encoded by the DCXR gene located on chromosome 17. (wikipedia.org)
Dicarbonyl/L-xylulose reductase (DCXR) is a highly conserved and phylogenetically widespread enzyme converting L-xylulose into xylitol. (nih.gov)
This gene provides instructions for making a protein called dicarbonyl and L-xylulose reductase (DCXR), which plays multiple roles in the body. (medlineplus.gov)
Lee SK, Son le T, Choi HJ, Ahnn J. Dicarbonyl/l-xylulose reductase (DCXR): The multifunctional pentosuria enzyme. (medlineplus.gov)
Dehydrogenase2
Y4LA_RHISN (Uncharacterized short-chain type dehydrogenase/reductase y4lA OS=Rhizobium sp. (citrusgenomedb.org)
The oleaginous yeast, Y. lipolytica, is most likely to have a xylose reductase (XYR), xylitol dehydrogenase (XDH), and xylulose kinase (XKS). (biomedcentral.com)
Xylitol7
In enzymology, an L-xylulose reductase (EC 1.1.1.10) is an enzyme that catalyzes the chemical reaction xylitol + NADP+ ⇌ {\displaystyle \rightleftharpoons } L-xylulose + NADPH + H+ Thus, the two substrates of this enzyme are xylitol and NADP+, whereas its 3 products are L-xylulose, NADPH, and H+. (wikipedia.org)
Xylulose Xylitol (Note conversion of ketone to alcohol) This enzyme belongs to the superfamily of short-chain oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. (wikipedia.org)
The systematic name of this enzyme class is xylitol:NADP+ 2-oxidoreductase (L-xylulose-forming). (wikipedia.org)
One of its functions is to perform a chemical reaction that converts a sugar called L-xylulose to a molecule called xylitol. (medlineplus.gov)
Without this protein, L-xylulose is not converted to xylitol, and the excess sugar is released in the urine. (medlineplus.gov)
An enzyme that plays a role in the PENTOSES and GLUCURONATES interconversion pathway by catalyzing the oxidation of XYLITOL to D-xylulose. (nih.gov)
Through expression of the heterogeneous xylose able source for fuel ethanol production without affecting metabolic pathway-either xylose reductase-xylitol dehy- the food and feed markets. (sagepub.com)
Protein4
The protein encoded by this gene acts as a homotetramer to catalyze diacetyl reductase and L-xylulose reductase reactions. (nih.gov)
There was also a decrease in the abundance of proteins associated with transcription (40 S ribosomal protein S30 (−26 fold), 40 S ribosomal protein S21 (−3 fold) and carbohydrate metabolism (l-xylulose reductase (−10 fold). (teagasc.ie)
Probable gamma-glutamyl phosphate reductase protein ProA. (ntu.edu.sg)
Xylose reductase2
The previously reported yeast strain BP10001, which expresses heterologous xylose reductase from Candida tenuis in mutated (NADH-preferring) form, stands for a series of other yeast strains designed with similar rational. (tugraz.at)
We also carried out a comprehensive investigation on the currently unclear role of coenzyme utilization, NADPH compared to NADH, for xylose reduction during co-fermentation of glucose and xylose.RESULTS:BP10001 and BP000, expressing C. tenuis xylose reductase in NADPH-preferring wild-type form, were used. (tugraz.at)
Pentosuria3
Essential pentosuria is a condition characterized by high levels of a sugar called L-xylulose in urine. (medlineplus.gov)
While essential pentosuria is caused by genetic mutations, some people develop a non-inherited form of pentosuria if they eat excessive amounts of fruits high in L-xylulose or another pentose called L-arabinose. (medlineplus.gov)
On the nature of L-xylulose reductase deficiency in essential pentosuria. (medlineplus.gov)
Enzyme2
This enzyme forms a system with a ferredoxin or a flavodoxin and an NAD(P)H-dependent reductase. (qmul.ac.uk)
The enzyme acts in the reverse direction, producing a 5:1 mixture of 3-methylbut-3-en-1-yl diphosphate and prenyl diphosphate. (qmul.ac.uk)
NADPH1
Catalyzes the NADPH-dependent reduction of several pentoses, tetroses, trioses, alpha-dicarbonyl compounds and L-xylulose. (nih.gov)
Synthase1
Engineering of Recombinant Poplar Deoxy-D-Xylulose-5-Phosphate Synthase (PtDXS) by Site-Directed Mutagenesis Improves Its Activity. (cmdm.tw)
Quinone1
3. Aldo-keto reductase 1C15 as a quinone reductase in rat endothelial cell: its involvement in redox cycling of 9,10-phenanthrenequinone. (nih.gov)
Glucose1
It is of economic interest to drogenase (XR-XDH) or xylose isomerase (XI)-S. cer- convert all lignocellulosic sugar fractions, predominantly evisiae can convert xylose to xylulose, which can then glucose and xylose, into ethanol at sufficiently high rates be natively catabolized (Matsushika et al. (sagepub.com)
Pentose1
The condition is so named because L-xylulose is a type of sugar called a pentose. (medlineplus.gov)
Coli1
Recombinant Human L-Xylulose Reductase is produced by our E.coli expression system and the target gene encoding Met1-Cys244 is expressed with a 6His tag at the N-terminus. (bonopusbio.com)
Pathway1
This pathway, also known as the 1-deoxy- D -xylulose 5-phosphate (DOXP) or as the 2- C -methyl- D -erythritol-4-phosphate (MEP) pathway, is found in most bacteria and in plant chloroplasts. (qmul.ac.uk)
Excessive1
The insufficiency of L-xylulose reductase activity causes an inborn error of metabolism disease characterized by excessive urinary excretion of L-xylulose. (wikipedia.org)
Expression1
15. 9,10-phenanthrenequinone induces monocytic differentiation of U937 cells through regulating expression of aldo-keto reductase 1C3. (nih.gov)
Human2
6. L-Xylulose reductase is involved in 9,10-phenanthrenequinone-induced apoptosis in human T lymphoma cells. (nih.gov)
8. Involvement of an aldo-keto reductase (AKR1C3) in redox cycling of 9,10-phenanthrenequinone leading to apoptosis in human endothelial cells. (nih.gov)