• In contrast, the absence of cysteamine is associated with defective epithelial cytoprotection in diabetes. (univ-mrs.fr)
  • Epithelial cytoprotection emerges as an important property of future therapeutic drugs for the treatment of airways inflammatory conditions. (lu.se)
  • Some studies suggest that amifostine exerts differential cytoprotection in normal versus neoplastic tissues, but this finding remains controversial. (aacrjournals.org)
  • Ectopic expression in mouse cells and CRISPR/Cas9 base editing of endogenous AGS loci revealed causal roles of one AGS-specific amino acid substitution in mediating cytoprotection by AGS ATP5G1. (elifesciences.org)
  • 2014 ) Cytoprotection by endogenous zinc in the vertebrate retina. (neurotree.org)
  • Since cancer stem cells have been hypothesized to play a role in refractory/relapsing cancers, in the present work we investigated if autophagy could represent a constitutive cytoprotection mechanism for glioblastoma stem-like cells (GSCs) and if the modulation of autophagic process could affect GBM growth and survival. (nature.com)
  • Hence, thanks to this complex mechanism, autophagy can provide energy supply to the cell and can represent a key cytoprotection mechanism allowing cell survival in unfavorable microenvironmental conditions such as those often found by cancer cells 7 . (nature.com)
  • The aim of this study was to analyze the ability of curcumin to protect against the mitochondrial impairment induced by high free fatty acids (HFFAs) and to determine the underlying mechanism for this cytoprotection. (spandidos-publications.com)
  • We explore the relations existing between cysteamine-driven inflammation versus cytoprotection in vivo and in human pathologies. (univ-mrs.fr)
  • Cytoprotection is a process by which chemical compounds provide protection to cells against harmful agents. (wikipedia.org)
  • It is therefore concluded that adaptive cytoprotection induced by low concentrations of NaCl and HCl could depend on their physical properties, while that of ethanol could act through its unique chemical property. (edu.hk)
  • Our results identify a naturally occurring variant of ATP5G1 from a mammalian hibernator that critically contributes to intrinsic cytoprotection against metabolic stress. (elifesciences.org)
  • It is described as a housekeeping enzyme, being responsible for cell-to-cell signaling, tissue homeostasis, and cytoprotection. (medscape.com)
  • These results indicate that whereas Vanin-1 is an essential regulator of inflammation following an acute stress, it also participates to tissue cytoprotection in more chronic diseases. (univ-mrs.fr)
  • 2015. Aryl hydrocarbon receptor-dependent stanniocalcin 2 induction by cinnabarinic acid provides cytoprotection against endoplasmic reticulum and oxidative stress. . (oregonstate.edu)
  • BAX and STAT are overexpressed and regulate clusterin expression in docetaxel-treated patients, indicating their role in cytoprotection from chemotherapy. (oncologynurseadvisor.com)
  • Thus, CEPT represents a unique poly-pharmacological strategy for comprehensive cytoprotection, providing a new rationale for efficient and safe utilization of hPSCs. (labroots.com)
  • PAR1 Agonists Stimulate APC-Like Endothelial Cytoprotection and Confer" by Karen De Ceunynck, Christian G. Peters et al. (marquette.edu)
  • Small-molecule activation of endothelial cytoprotection through PAR1 represents an approach for treatment of thromboinflammatory disease and provides proof-of-principle for the strategy of targeting the cytoplasmic surface of GPCRs to achieve pathway selective signaling. (marquette.edu)
  • 2015. Aryl hydrocarbon receptor-dependent stanniocalcin 2 induction by cinnabarinic acid provides cytoprotection against endoplasmic reticulum and oxidative stress. . (oregonstate.edu)
  • It is known [ 6 ] that the Kelch-like ECH-associated protein 1 (Keap1)-Nrf2 system plays a central role in cytoprotection against oxidative injury. (molvis.org)
  • Mr Exon's research and academic profile includes published articles in high impact, peer-reviewed journals on molecular predictors of prognosis in oeosophago-gastric cancer surgery, as well as presenting at both national and international conferences on the cellular stress response of laparoscopic surgery and cytoprotection. (nuffieldhealth.com)
  • Cytoprotection is a process by which chemical compounds provide protection to cells against harmful agents. (wikipedia.org)
  • Mesenchymal stromal cells promote tissue cytoprotection. (frontiersin.org)
  • Inhibition of PI3K Class IA Kinases Using GDC-0941 Overcomes Cytoprotection of Multiple Myeloma Cells in the Osteoclastic Bone Marrow Microenvironment Enhancing the Efficacy of Current Clinical Therapeutics. (ox.ac.uk)
  • Mohan S, Robinson T, Allen N, Armstrong L, Stevens S. Morphine-Mediated Cytoprotection against Hemin in SK-N-SH and A172 Cells. (liberty.edu)
  • HSP70 molecules playa critical role in cytoprotection against toxic exposures and are important as molecular chaperones in antigen processing and presentation. (cdc.gov)
  • Health and cellular impacts of air pollutants: from cytoprotection to cytotoxicity. (nih.gov)
  • Our studies identify beryllium -regulated genes and suggest that HSP70, in particular, may playa pivotal role in cytoprotection and the early immune response to beryllium salts. (cdc.gov)
  • Here, we demonstrate that EBs and various organoid models (e.g., brain, gut, and kidney) can be optimized by using the CEPT small molecule cocktail, a polypharmacology approach that ensures cytoprotection and cell survival. (nih.gov)