• Beta-crystallin B3 is a protein that in humans is encoded by the CRYBB3 gene. (wikipedia.org)
  • This gene, a beta basic group member, is part of a gene cluster with beta-A4, beta-B1, and beta-B2. (wikipedia.org)
  • Human CRYBB3 genome location and CRYBB3 gene details page in the UCSC Genome Browser. (wikipedia.org)
  • All six exons of crystallin, beta A4 gene ( CRYBA4 ) were amplified by PCR methods and direct sequencing. (molvis.org)
  • beta and gamma crystallins are also considered as a superfamily. (wikipedia.org)
  • Examination of crystallin genes not yet linked to human disease identified a novel cataract gene, CRYBA2, a member of the βγ-crystallin superfamily. (nih.gov)
  • Crystallins are the dominant structural components of the vertebrate eye lens. (nih.gov)
  • the CRYBB3 mutation represents the first dominant allele in this gene and demonstrates incomplete penetrance. (nih.gov)
  • Beta-crystallin B3 is a protein that in humans is encoded by the CRYBB3 gene. (wikipedia.org)
  • Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. (wikipedia.org)