Connectome. Medical search. Frequent questions

The Developing Human Connectome Project (dHCP) is a study to map the growth of the baby's brain during pregnancy and how it continues to develop after birth. (developingconnectome.org)
The Developing Human Connectome Project is funded through a Synergy Grant by the European Research Council (ERC) under the European Union's Seventh Framework Programme (FP/2007-2013) / ERC Grant Agreement n. 319456. (developingconnectome.org)
Abstract$$ $$The developing Human Connectome Project (dHCP) aims to create a detailed 4-dimensional connectome of early life spanning 20 to 45 weeks post-menstrual age. (ox.ac.uk)

In addition, the Connectome Coordination Facility, funded by Blueprint in 2015, maintains a central data repository for HCP data and offers advice to the research community regarding data collection strategies and harmonization. (nih.gov)
We are happy to field any questions or requests for more information regarding the Connectome Coordination Facility as a whole. (humanconnectome.org)
The Human Connectome Project and Connectome Coordination Facility are funded by the National Institutes of Health, and all information in this site is available to the public domain. (humanconnectome.org)
Importantly, all of the data produced by HCP is freely shared with the research community through a customized database created by the Blueprint funded Connectome Coordination Facility. (nih.gov)
QuNex implementacija HCP pipelines bo uporabljena za procesiranje podatkov Koordinacijske podpore za konektom (Connectome Coordination Facility, CCF) za projekte Staranje (Lifespan Aging), Razvoj (Lifespan Development) in Konektomi vezani na človeške bolezni (Connectomes Related to Human Disease, CRHD). (mblab.si)

The initial phase of the Human Connectome Project (HCP) will be complete in September 2015. (nih.gov)
Scans of an individual's brain activity are emerging as powerful predictive tools, thanks to the Human Connectome Project (HCP), an initiative of the National Institutes of Health. (nih.gov)
The Neuroscience Blueprint is supporting a Lifespan Human Connectome Project (L-HCP) to extend the Human Connectome Project (HCP) ( http://www.neuroscienceblueprint.nih.gov/connectome ) to map connectivity in the developing, adult, and aging human brain. (nih.gov)
The overall purpose of this five year Human Connectome Project (HCP) is to develop and share knowledge about the structural and functional connectivity of the human brain. (nih.gov)
The NIH Blueprint for Neuroscience Research expects to commit approximately $6 million per year in total costs to fund one Human Connectome Project cooperative agreement. (nih.gov)
The NIH Human Connectome Project is an ambitious effort to map the neural pathways that underlie human brain function. (nih.gov)
The Connectome Celebration will gather connectomics researchers and the research community alike to celebrate the achievements of the Connectome Project to date. (nih.gov)
This mailing list is used by the Human Connectome Project to make announcements of new data releases, updated software, and upcoming events. (humanconnectome.org)
The member universities of the Human Connectome Project take privacy very seriously, whether dealing with participant data or the data of those visiting this website. (humanconnectome.org)
1000 Functional Connectomes Project has a wiki that can be found here . (nitrc.org)
Connectomes were mapped for 889 healthy adults participating in the Human Connectome Project. (mit.edu)
I am preparing to analyze human connectome project DTI data and there are four different scans for each participant (scan_1_AP, scan_1_PA, scan_2_AP, and scan_2_PA). (nih.gov)
Yamazaki has been Blockchain Project Manager in CyberAgent as the leader of its blockchain projects, also, he has assisted Moneytree in developing one financial data aggregation platform for individual consumers and enterprises Yamazaki is experienced in the development of blockchain projects, and he has deep insight into financial indus- try.He is Connectome COO, in charge of global marketing and business development. (connectome.one)
MBLab se je projektu skupaj s sodelavci iz N3 ekipe na Univerzi Yale pridružil kot podizvajalec z namenom razvoja QuNex za podporo Projekta človeškega konektoma (Human Connectome Project, HCP) za uporabo HCP pipelines v okviru QuNex Docker in Singularity kontejnerjev. (mblab.si)
The Human Connectome Project (HCP) is a project to construct a map of the complete structural and functional neural connections in vivo within and across individuals. (openhealthnews.com)
Connectome is an ambitious project that will provide a seamless user experience between their home, place of work and all the places in between including vehicles, shops and transportation hubs. (coincheckup.com)
Connectome Workbench is a brain visualization, analysis and discovery tool for fMRI and dMRI brain imaging data, including functional and structural connectivity data generated by the Human Connectome Project. (inm7.de)
Our project deals with this new framework of the modern neuroscience, the connectomics, which examines the anatomical organization and the functioning of the brain through the connectome to relate it with the cognitive functioning. (cnrs.fr)
Mapping the brain: The Human Connectome Project There is an explosion of new techniques to study and understand the mysteries of the brain. (connectingthegrowingbrain.com)
The science behind the project: what is a connectome? (developingconnectome.org)
We will generate a structural connectome for quintessential Human Connectome Project subject 100307. (mrtrix.org)
Tradeoffs in pushing the spatial resolution of fMRI for the 7T Human Connectome Project. (ox.ac.uk)
Using the processing pipeline developed by the Human Connectome Project, we demonstrate that high resolution images acquired at 7T provide increased functional contrast to noise ratios with significantly less partial volume effects and more distinct spatial features, potentially allowing for robust individual subject parcellations and descriptions of fine-scaled patterns, such as visuotopic organization. (ox.ac.uk)
Genomic kinship construction to enhance genetic analyses in the human connectome project data. (ox.ac.uk)
We tested this in 1,046 participants of the Human Connectome Project (HCP) (480 M/566 F) recruited from the Missouri twin registry. (ox.ac.uk)

Despite such complex and variable structure-function mappings, the connectome is an indispensable basis for the mechanistic interpretation of dynamic brain data, from single-cell recordings to functional neuroimaging. (wikipedia.org)
The connectome will significantly increase our understanding of how functional brain states emerge from their underlying structural substrate, and will provide new mechanistic insights into how brain function is affected if this structural substrate is disrupted. (wikipedia.org)
Sleep and the functional connectome are research areas with considerable overlap. (nih.gov)
Dynamic functional connectivity in the static connectome of Caenorhabditis elegans. (nih.gov)
The "programs" folder contains the computer programs for ranking lists of genes within a gene-specific connectome, clustering and plotting the genes by the functional genomic alignment (FGA) approach and generating gene-specific connectomes (also see (3) below). (rockefeller.edu)
Our central hypothesis to test is if the symmetries in connectivity underly the synchronization of neuronal population activity, and therefore can be used to discover functional units within complex connectome data. (nih.gov)
Our graph theoretical toolbox will classify the symmetries of all connectomes thereby identifying neural circuits that potentially form functional building blocks. (nih.gov)
A machine learning approach based on canonical correlation analysis was used to identify latent dimensional associations of the resting-state functional connectome with multidomain behavioral assessments including cognitive functions and psychopathological measures. (nih.gov)
This functional connectome pattern was highly heritable (h2 = 74.42%, 95% CI: 56.76%-85.42%), exhibited a dose-response relationship with the cumulative number of psychiatric disorders assessed concurrently and at 2 years post-magnetic resonance imaging scan, and predicted the transition of diagnosis across disorders over the 2-year follow-up period. (nih.gov)
The action of these normal subgroups partitions the connectome into sectors of neurons that match broad functional categories. (brainanalysis.net)
Functional Connectome Hierarchy Distortions in Female Nurses With Occupational Burnout and Its Gene Expression Signatures. (bvsalud.org)
Functional connectome impairments associated with occupational burnout were widely distributed, involving both low-level sensorimotor cortices and high-level association cortices. (bvsalud.org)
To investigate whether there are hierarchical perturbations in the functional connectomes and if these perturbations are potentially influenced by genetic factors in nurses who feel "burned out. (bvsalud.org)

2004). Established methods of brain research, such as axonal tracing, provided early avenues for building connectome data sets. (wikipedia.org)

Connectomics" (Hagmann, 2005) has been defined as the science concerned with assembling and analyzing connectome data sets. (wikipedia.org)
Tutorials from the Virtual Fly Brain "Hacking the connectome" workshop that was run in collaboration with the Drosophila Connectomics Group based at the Dept of Zoology, University of Cambridge. (virtualflybrain.org)

A connectome is constructed by tracing the neuron in a nervous system and mapping where neurons are connected through synapses. (wikipedia.org)
The term "connectome" was more recently popularized by Sebastian Seung's I am my Connectome speech given at the 2010 TED conference, which discusses the high-level goals of mapping the human connectome, as well as ongoing efforts to build a three-dimensional neural map of brain tissue at the microscale. (wikipedia.org)
Comparing results across multiple connectome mapping pipelines suggested that modeling polysynaptic communication is particularly beneficial in sparse high-resolution connectomes. (mit.edu)
Mapping of the human connectome offers a unique opportunity to understand the complete details of neural connectivity. (openhealthnews.com)
These insights were possible in spite of the fact that the mapping of connectomes is a "snapshot" technique: neuronal networks can be measured in biopsies of brain tissue, but cannot be further followed over time in the same piece of brain. (mpg.de)

Maintain the existing data repository infrastructure for Human Connectome data and expand to include Connectome data from other research laboratories. (nih.gov)
The significance of the connectome stems from the realization that the structure and function of the human brain are intricately linked, through multiple levels and modes of brain connectivity. (wikipedia.org)
Indeed, the foundation of human cognition lies in the pattern of dynamic interactions shaped by the connectome. (wikipedia.org)
In their 2005 paper, "The Human Connectome, a structural description of the human brain", Sporns et al. (wikipedia.org)
We propose to call this dataset the human "connectome," and we argue that it is fundamentally important in cognitive neuroscience and neuropsychology. (wikipedia.org)
I am exploring the human connectome dataset with AFNI, doing standard seed-based connectivity to try to replicate some studies RSFC out there. (nih.gov)
The participant data from our research into the Human Connectome that is stored in our XNAT server is de-identified, and contains no personal health information (PHI). (humanconnectome.org)
The Connectomes Related to Human Disease Notice of Funding Opportunity , supported by the National Eye Institute ( NEI ), National Institute on Alcohol Abuse and Alcoholism ( NIAAA ), National Institute on Aging ( NIA ), National Institute on Drug Abuse ( NIDA ), National Institute of Mental Health ( NIMH ), and National Institute of Neurological Disorders and Stroke ( NINDS ) awarded fourteen projects in FY2015 and FY2016. (nih.gov)
A gene-specific connectome contains the set of all available human genes sorted on the basis of their predicted biological proximity to the specific gene of interest. (rockefeller.edu)
The HGC is a powerful approach for human genotype-phenotype high-throughput studies, for which it can be used to rank any list of genes within a gene-specific connectome for an experimentally validated core gene. (rockefeller.edu)
The human gene connectome server (HGCS) is an effective and easy-to-use interactive web server that enables researchers to prioritize any list of genes by their biological proximity to defined core genes (i.e. genes that are known to be associated with the phenotype), and to predict novel gene pathways. (rockefeller.edu)
The "human gene -specific connectomes" folder contains a gene-specific connectome file for each human gene. (rockefeller.edu)
Alternatively you can download all human gene -specific connectomes in one compressed file. (rockefeller.edu)
Please refer to this paper for additional information about the human gene connectome concept and its applications in morbid allele discovery and genotype-phenotype studies. (rockefeller.edu)
Connectome allows the users to interface with a familiar AR-enabled Virtual Human Agent (VHA) that can behave like humans such as detecting objects, recognizing sounds and reacting in real-time across devices and locations. (coincheckup.com)
Diffusion MRI reflects the random diffusion of water molecules, which is affected by the microscopic structure of tissue, here the human brain, enabling us to infer the microarchitecture of these tissues en term of local density and structural organization. (cnrs.fr)

2005). A connectome at the macroscale (millimeter resolution) attempts to capture large brain systems that can be parcellated into anatomically distinct modules (areas, parcels or nodes), each having a distinct pattern of connectivity. (wikipedia.org)
ASSESSMENT Gradient-based techniques were used to depict the perturbations in the multi-dimensional hierarchical structure of the macroscale connectome . (bvsalud.org)

Building on the success of the HCP, Blueprint launched the second phase of the Connectome Program by creating the Lifespan Connectome in 2015. (nih.gov)
In addition to expanding the age distribution of HCP research participants, in 2014 a subset of six Blueprint Institutes invested in collecting connectome data from subjects with certain clinical diagnoses. (nih.gov)

Workbench Command is a set of command-line tools that can be used to perform simple and complex operations within Connectome Workbench. (humanconnectome.org)
Get Connectome Workbench! (humanconnectome.org)
Version 1.5.0 of the Connectome Workbench is now publicly available for download for Mac, Windows and Linux. (humanconnectome.org)

Vulnerability-Based Critical Neurons, Synapses, and Pathways in the Caenorhabditis elegans Connectome. (nih.gov)
The neural connectome of the nematode Caenorhabditis elegans has been completely mapped, yet in spite of being one of the smallest connectomes (302 neurons), the design principles that explain how the connectome structure determines its function remain unknown. (brainanalysis.net)
A complete map of the cerebral connections, the connectome, is required for interpreting measurements of the signals transmitted between neurons. (cnrs.fr)
First, the connectome is principally about structure, about the extensive but finite set of physical links between the neurons, namely the axons. (cnrs.fr)

Topological cluster analysis reveals the systemic organization of the Caenorhabditis elegans connectome. (nih.gov)

Beyond the connectome: how neuromodulators shape neural circuits. (nih.gov)

Spectral clustering and an original multi-class Hopfield network (MHN) method is applied to solve the problem, each working with a different analytical framework: MHN works in the diffusion space to generate individual parcellations, while spectral clustering works on standard space averaged connectome to generate group level atlases. (umd.edu)
Eleven major white matter tracts that constitute the structural connectome were defined using diffusion tensor imaging. (nih.gov)
We modelled N = 8183 structural connectomes from UK Biobank using six different structural network weightings obtained from diffusion MRI. (ed.ac.uk)

The initial results from the HCP suggest that the data are of very high quality and that correlations between the connectomes and the measured behavioral data are being discovered. (nih.gov)

Connectome Celebration 2016 / Office of Technology Development and Coordination, NIMH, NIH. (nih.gov)

The theory of connectome-specific harmonic waves suggests one thing that happens in the brain is that oscillations in neuron activity (brainwaves) interact to form harmonics (correlated brainwaves that form patterns) that may explain certain aspects of brain and thereby mental activity. (lesswrong.com)

Given the methodological uncertainties involved in inferring connectivity from the primary experimental data, and given that there are likely to be large differences in the connectomes of different individuals, any unified map will likely rely on probabilistic representations of connectivity data (Sporns et al. (wikipedia.org)
Massachusetts General Hospital/Harvard University and the University of California Los Angeles (UCLA) - co-led by Dr. Bruce Rosen and Dr. Arthur Toga - set out to create a new magnetic resonance imager optimized for measuring connectome data. (nih.gov)
While research participants in the original HCP studies were 22-35 years old, the Lifespan Connectome extended data collection from healthy subjects of all ages. (nih.gov)

While FC was the most accurate predictor of behavior, communication models, in particular communicability and navigation, improved the performance of structural connectomes. (mit.edu)

We aimed to establish whether accounting for polysynaptic communication in structural connectomes would improve prediction of interindividual variation in behavior as well as increase structure-function coupling strength. (mit.edu)

Here we examine the connectome, defined as the interconnected brain regions or networks that support cognition, and focus on its structural basis provided by white matter tracts. (nih.gov)

Valdes, PA , Ng, S, Bernstock, JD & Duffau, H 2023, ' Development of an educational method to rethink and learn oncological brain surgery in an "a la carte" connectome-based perspective ', Acta Neurochirurgica . (utmb.edu)

Jinn, the world's first AI Web3 search engine based on GPT3.5, is about to make the world ConnectoMe! (connectome.one)

The symmetries are graph automorphisms or symmetry permutations, i.e. specific similarities in the connectivity patterns of the connectome, that predict synchronization of neural populations. (nih.gov)

The output file in this case would contain the list of genes extracted from the gene-specific connectome, ranked by biological distance, which can be opened in Microsoft Excel. (rockefeller.edu)

This video shows Anne Elk's theory: Zen Faulkes reminded us of its existence, as he explained the new theory someone has advanced about The Connectome. (improbable.com)

A connectome map is being built in adults, but this is the first connectome study of early life. (developingconnectome.org)

This map of the connections in the brain is called a connectome and it will allow doctors and scientists to better understand how the brain normally grows and also how problems might arise. (developingconnectome.org)

CONCLUSIONS: These findings provide preliminary evidence for a transdiagnostic connectome-based measure that underlies individual differences in the development of psychiatric disorders during early adolescence. (nih.gov)

In a similar manner, one could consider the brain connectome, set of all neuronal connections, as one single entity, thus emphasizing the fact that the huge brain neuronal communication capacity and computational power critically relies on this subtle and incredibly complex connectivity architecture. (wikipedia.org)
This highlights that model complexity is unlikely to improve detection of associations between structural connectomes and complex phenotypes with the current sample size. (ed.ac.uk)

Below you can watch the recorded introduction session of our workshop and follow along with the workshop notebooks we work through to show examples of how you can use the available {{ ref "tools.md" tools }} to explore and analyse the published connectomes available on VFB. (virtualflybrain.org)

The archetypical example is the complete reconstruction of the C. elegans connectome. (nih.gov)

To account for polysynaptic signaling, connectomes were transformed into communication matrices for each of 15 different network communication models. (mit.edu)
We have developed a network theoretical toolbox to extract the symmetries of the connectome. (nih.gov)

Anatomy3

Diseases1

Analytical, Diagnostic and Therapeutic Techniques and Equipment5

Information Science1

Developing Human Connectome Project3

Coordination Facility5

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Functional13

Building connectome data1

Connectomics2

Mapping5

Human16

Macroscale2

Blueprint2

Workbench3

Neurons4

Caenorhabditis1

Neural circuits1

Diffusion3

Behavioral1

NIMH1

Neuron1

Data3

Navigation1

Prediction1

Tracts1

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Search1

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Genes1

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