• There is a paucity of data on incidence, prevalence and mortality associated with non-cystic fibrosis bronchiectasis. (ersjournals.com)
  • Using primary care data (Clinical Practice Research Datalink (CPRD)), we aimed to establish the incidence and prevalence of non-cystic fibrosis bronchiectasis in UK adults from 2004 to 2013. (ersjournals.com)
  • In contrast, there have been many randomised trials in chronic obstructive pulmonary disease (COPD) and cystic fibrosis (CF) over the past 20 years, leading to a tendency for bronchiectasis researchers to use end-points and therapies previously developed in these two diseases. (ersjournals.com)
  • Cystic fibrosis is a genetic disorder that affects the production of mucus and can lead to the development of bronchiectasis. (ayurvedguru.com)
  • Chronic respiratory failure is a term used to describe very serious (advanced) cases of bronchiectasis, which are more common in low- and middle-income countries and in people with advanced cystic fibrosis. (medanta.org)
  • Saad AB, Migaou A, Fahem N, Mhamed SC, Rouatbi N, Joobeur S. Severity assessment of non-cystic fibrosis bronchiectasis by the FACED score. (patsjournal.org)
  • This study aimed to determine the relation of the FACED score (a multidimensional score contributing to stratify patients into risk categories) with the severity of non-cystic fibrosis bronchiectasis (NCFB) among our population. (patsjournal.org)
  • In the treatment of severe lung infections, such as those found in individuals with cystic fibrosis or bronchiectasis, the use of antibiotics can often lead to drug resistance and serious side effects. (aboutmanukahoney.com)
  • Treating infections in individuals with cystic fibrosis and bronchiectasis can be challenging due to drug resistance. (aboutmanukahoney.com)
  • In conclusion, the combination of amikacin and manuka honey shows great promise as a potential treatment for pulmonary infections in individuals with cystic fibrosis and bronchiectasis. (aboutmanukahoney.com)
  • however, its presence, frequency, and clinical significance in non-cystic fibrosis bronchiectasis remain unclear. (a-star.edu.sg)
  • Cystic type on HRCT is found to be common in bronchiectasis patients in our region. (jclmm.com)
  • CONCLUSION: In children with cystic fibrosis, positive Aspergillus BAL cultures at age 5 years were associated contemporaneously with air trapping but not bronchiectasis. (edu.au)
  • The aim of this study was to 1) establish the relationship between the 6-Minute Walk Distance (6MWD), disease severity and Health-Related Quality of Life (HRQOL) and 2) identify predictors of exercise tolerance in adults with bronchiectasis. (nih.gov)
  • Measures of HRQOL demonstrated a stronger association with the 6MWD compared to physiological measures of disease severity in patients with predominantly mild to moderate bronchiectasis. (nih.gov)
  • Interventions that prevent hospitalized exacerbations and reduce severity of childhood bronchiectasis with even moderate effectiveness are likely to result in substantial hospital costs savings. (asthmafoundation.org.nz)
  • At the time of review, 11 patients had died (median age, FEV %predicted, and bronchiectasis severity index (BSI) 59 years, 38% and 15.5 respectively), all due to respiratory failure, and as expected, all were classed severe on BSI. (biomedcentral.com)
  • highlighting the factors for an unfavorable evolution in different degrees of severity bronchiectasis. (cnaa.md)
  • The study demonstrated the prognostic value of imaging scores and multidimensional indices in assessing the severity of the disease and the impact on the quality of life of patients with bronchiectasis. (cnaa.md)
  • Based on the study, the role of several inflammatory markers in the evaluation of the exacerbation severity, as well as the value of various clinical and paraclinical tools in the multidimensional assessment of bronchiectasis patients was demonstrated, highlighting the predictors. (cnaa.md)
  • Methods: Patients with bronchiectasis were recruited in Asia (Singapore and Malaysia) and the United Kingdom (Scotland) (n = 238), forming the Cohort of Asian and Matched European Bronchiectasis, which matched recruited patients on age, sex, and bronchiectasis severity. (a-star.edu.sg)
  • Methods In this prospective observational study, baseline lung function, quality of life, exercise tolerance, severity of bronchiectasis and PA were recorded. (klinikrespirasimalang.com)
  • Aim: To study HRCT pattern in patients of bronchiectasis. (jclmm.com)
  • Conclusion:Results of this study showed a higher number of positive obstructive pattern in patients of bronchiectasis and percentage reversibility is also very high. (who.int)
  • While exercise intolerance has been identified in patients with bronchiectasis, the clinical determinants of the 6MWT in this population have not been examined. (nih.gov)
  • Bronchiectasis is a long-term respiratory condition characterised by persistent airway infection and recurrent exacerbations in the presence of structurally abnormal bronchi. (ersjournals.com)
  • The per episode healthcare cost burden of hospitalizations for paediatric bronchiectasis exacerbations is substantial. (asthmafoundation.org.nz)
  • To determine the effect of anticholinergic therapy in acute exacerbations and stable bronchiectasis. (cochrane.org)
  • Hemoptysis (coughing up blood) can occur, especially during acute exacerbations or when bronchiectasis is severe. (ayurvedguru.com)
  • The first survey (10 languages) was completed by 225 respondents (parents of CYP with bronchiectasis and adults with bronchiectasis diagnosed in childhood) from 21 countries. (ersjournals.com)
  • Based on the study, the etiological diversity of bronchiectasis in adults was demonstrated, including the rare etiological forms, with the presentation of imaging features and the needed paraclinical tests for their confirmation. (cnaa.md)
  • Chronic neutrophilic inflammation, in both the presenceand absence of infection, is a feature of bronchiectasis in adults andchildren. (edu.au)
  • Weincluded this study of 25 adults with chronic lung disease (only 32% of peopleincluded in the trial had bronchiectasis), as the other conditions were linkedto development of bronchiectasis, and all were characterised by chronic sputumproduction. (edu.au)
  • One small trial reported a reduction in sputum production andimproved dyspnoea among adults with chronic lung disease who were treated withinhaled indomethacin, indicating that additional studies on the efficacy ofNSAIDs for treatment of patients with bronchiectasis are warranted. (edu.au)
  • Criteria and definitions for the radiological and clinical diagnosis of bronchiectasis in adults for use in clinical trials: international consensus recommendations. (jclmm.com)
  • CONCLUSIONS: Frailty modifies the intervention effect of CY on pain among older adults with lower extremity OA, underscoring the importance of assessing frailty to improve the management of pain in this population. (cdc.gov)
  • The aim of this study was to investigate the association between (i) any physical activity (PA) variable and (ii) sedentary time with hospitalisation due to exacerbation in adults with bronchiectasis. (klinikrespirasimalang.com)
  • To evaluate the use of end-points in bronchiectasis trials, we conducted a systematic review of published bronchiectasis trials from 2008 to 2018 and extracted end-points used, definitions, methods of analysis and responsiveness. (ersjournals.com)
  • Materials and Methods: In this study 150 bronchiectasis patients coming to Dhiraj Hospital, Pipariya, Vadodara within a span of 18 months were included. (jclmm.com)
  • Patients with preexisting bronchiectasis are susceptible to NTM. (nih.gov)
  • Nevertheless, patients with preexisting bronchiectasis are susceptible to NTM but the prevalence of NTM pulmonary infection in different species and geographical areas is still not fully understood. (nih.gov)
  • The relevant data of the prevalence of NTM in patients with bronchiectasis were retrieved by searching the main databases such as PubMed, MEDLINE, Cochrane Library, and EMBASE. (nih.gov)
  • The results of the meta-analysis showed that the overall prevalence of NTM was 9.3% in patients with bronchiectasis. (nih.gov)
  • Our findings suggested that the prevalence NTM infection is high in patients with bronchiectasis. (nih.gov)
  • Thirty two patients with idiopathic bronchiectasis were randomly allocated to one of three groups: PR plus sham IMT (PR-SHAM), PR plus targeted IMT (PR-IMT), or control. (bmj.com)
  • 8 Theoretically, one would therefore expect pulmonary rehabilitation to be as effective in bronchiectasis as it is in COPD, but to date only one study has been performed which included only seven patients with the disease. (bmj.com)
  • Conclusions Patients seemed more exposed to alerts during periods of AF. (researchgate.net)
  • The European Respiratory Society (ERS) published guidelines for bronchiectasis management in 2017 which recommends a minimum bundle of investigations that includes complete blood count (CBC), Immunoglobulin A (IgA), Immunoglobulin M (IgM) and immunoglobulin G (IgG) in all bronchiectasis patients [ 1 ] with further investigations to be done on the clinical suspicion and on the treating physician's discretion. (biomedcentral.com)
  • Recent research has shown that further immunological testing is usually needed to identify more patients with treatable immunodeficiencies such as primary or secondary antibody deficiencies [ 10 ] and doing so can alter the course of bronchiectasis for those patients. (biomedcentral.com)
  • The aim of our study was to characterise the lipids obtained from serum and airways in bronchiectasis patients in the stable state. (ed.ac.uk)
  • 6 healthy volunteers, 10 patients with mild, 15 with moderate and 9 with severe bronchiectasis were recruited. (ed.ac.uk)
  • LXA4 improved blood and airways neutrophil phagocytosis and bacterial killing in bronchiectasis patients. (ed.ac.uk)
  • To determine the etiological and phenotypical peculiarities, correlated with the clinical, imaging, functional and microbiological patterns in bronchiectasis for the proposal of the management strategy in adult patients. (cnaa.md)
  • For the first time, the utility of the immunochromatographic rapid test was demonstrated for the identification of cases of aspergillosis among bronchiectasis patients. (cnaa.md)
  • Several bronchiectasis phenotypes were revealed based on the analysis of clinical, radiological, microbiological and ventilatory patterns and their role in the personalized approach for patients with bronchiectasis in the Republic of Moldova was shown. (cnaa.md)
  • The long-term monitoring of the bronchiectasis patients from a multidimensional perspective highlighted some correlations according to the etiological, imaging, ventilatory patterns and chronic airway infections in the bronchiectasis patients. (cnaa.md)
  • Monocenter, retrospective systematic study of all patients with a chronic inflammatory rheumatic disease and concomitant bronchiectasis, seen between 2000 and 2009. (biomedcentral.com)
  • Lower respiratory tract infectious events are frequent among patients receiving biologics for chronic inflammatory rheumatic disease associated with bronchiectasis. (biomedcentral.com)
  • the prevalence was very high since bronchiectasis was evidenced in 18 to 30% of patients. (biomedcentral.com)
  • The objective of this study was to evaluate the risk of lower respiratory tract infectious events among patients followed for bronchiectasis and receiving non biologic DMARDs and/or biologic treatments for rheumatic diseases, and to assess factors associated with infections, and in particular disease-modifying treatments. (biomedcentral.com)
  • The clinical data suggest that testing should be primarily offered to patients with COPD, emphysema, and/or bronchiectasis. (biomedcentral.com)
  • Samples from patients with respiratory diseases other than COPD, including poorly controlled asthma or bronchiectasis, also presented AATD mutations. (gencat.cat)
  • We evaluated secondary safety outcomes in a comparative effectiveness study of chronic inhaled corticosteroids (ICS) and macrolide monotherapy in bronchiectasis patients. (elsevierpure.com)
  • Results Of 285 043 Medicare patients with bronchiectasis, we identified 6500 (2%) macrolide and 83589 (29%) ICS new users. (elsevierpure.com)
  • The increased risk of hearing loss in macrolide users compared to ICS users in older bronchiectasis patients should be balanced against known benefits of macrolides. (elsevierpure.com)
  • Conclusions: Allergic sensitization occurs at high frequency in patients with bronchiectasis recruited from different global centers. (a-star.edu.sg)
  • Improving endophenotyping of sensitized bronchiectasis, a clinically significant state, and a "treatable trait" permits therapeutic intervention in appropriate patients, and may allow improved stratification in future bronchiectasis research and clinical trials. (a-star.edu.sg)
  • BronchandNTM360social is an online community for individuals affected by Bronchiectasis and/or NTM, including patients, family members, caregivers, physicians and other healthcare providers. (bronchiectasisandntminitiative.org)
  • Clinical, radiologic, and functional evaluation of 304 patients with bronchiectasis. (jclmm.com)
  • Sundrarajaperumal A, Nedunchezhian R, Ranganathan D, Sundar V. Radiological and pulmonary function test assessment in clinically stable bronchiectasis patients. (jclmm.com)
  • Objective: To investigate prevalence and spatial distribution of air cysts and bronchiectasis associated with mechanical ventilation in patients with severe acute respiratory distress syndrome. (elsevierpure.com)
  • Bronchiectasis were found in 42% of patients at the time of diagnosis. (bvsalud.org)
  • Background Patients with bronchiectasis have a less active lifestyle than healthy peers, but the association with hospital admission has not been explored. (klinikrespirasimalang.com)
  • Results Sixty-four patients with bronchiectasis were analysed, of whom 15 (23%) were hospitalised during the follow-up. (klinikrespirasimalang.com)
  • Patients who walked ≤6290 steps per day or spent ≥7.8 h per day in sedentary behaviour had an increased risk of hospital admission due to bronchiectasis exacerbation at 1-year follow-up. (klinikrespirasimalang.com)
  • Objectives: To determine the frequency of obstructive pattern of spirometry in bronchiectasis patients. (who.int)
  • Total 143 patients with bronchiectasis having age 30-60 years either male or female and having duration of symptoms ?1 years were selected for this study. (who.int)
  • Results: Total 143 patients with Bronchiectasis were selected for this study. (who.int)
  • Out of 143 patients of Bronchiectasis, Positive obstructive pattern was noted in 80 (55.9%) patients and reversibility was noted in 45 (56.25%) patients. (who.int)
  • A group of 51 patients diagnosed with interstitial lung diseases, bronchiectasis, asthma and scoliosis were studied. (who.int)
  • Une étude rétrospective a été menée à Riyad (Arabie saoudite) pour connaître l'impact de la rééducation pulmonaire d'une part sur les paramètres respiratoires d'un groupe de patients en consultation externe pour des affections pulmonaires chroniques autres que la bronchopneumopathie chronique obstructive (BPCO) et d'autre part sur leur utilisation des soins de santé. (who.int)
  • It is useful in patients with chronic or recurring symptoms and in those with possible complications such as allergic bronchopulmonary aspergillosis and bronchiectasis. (medscape.com)
  • Conclusion: This study demonstrated a high burden of abnormal lung function in patients attending clinics due to chronic respiratory symptoms. (who.int)
  • CONCLUSIONS: The evidence on the optimal strategies to prevent, diagnose, and treat VTE in patients with COVID-19 is sparse but rapidly evolving. (bvsalud.org)
  • Repeated or severe respiratory infections, such as pneumonia, whooping cough (pertussis), and tuberculosis, can cause damage to the airways and contribute to the development of bronchiectasis. (ayurvedguru.com)
  • The 2017 European Respiratory Society (ERS) guidelines for bronchiectasis were unable to recommend any pharmacotherapy with strong evidence because of a lack of trials demonstrating statistically significant benefits [ 3 ]. (ersjournals.com)
  • This study aimed to (i) identify health service costs of hospitalizations and (ii) factors associated with these costs in children admitted to an Australian paediatric hospital following an acute exacerbation of their bronchiectasis. (asthmafoundation.org.nz)
  • No formal recommendations can be made about the use of anticholinergic therapy in acute or stable bronchiectasis based on the literature currently available. (cochrane.org)
  • Conclusions Macrolides were not associated with an elevated risk of acute cardiac events compared to ICS. (elsevierpure.com)
  • Bronchiectasis can coexist and/or be associated with other long-term respiratory conditions, such as chronic obstructive pulmonary disease (COPD) and asthma, as well as many nonrespiratory diseases, including rheumatoid arthritis and HIV infection. (ersjournals.com)
  • Conclusions: Use of diacetyl and other flavoring chemicals to make powdered flavorings puts workers at high risk of developing severe fixed obstructive lung disease. (cdc.gov)
  • Despite paediatric bronchiectasis being recognized increasingly worldwide, prior reports of hospitalization costs for bronchiectasis in children are lacking. (asthmafoundation.org.nz)
  • However, there are no published data on patient-driven clinical needs and/or research priorities for paediatric bronchiectasis. (ersjournals.com)
  • The European Lung Foundation and the European Respiratory Society Task Force for paediatric bronchiectasis created an international roadmap of clinical and research priorities to guide, and as an extension of, the clinical practice guideline. (ersjournals.com)
  • On thoracic radiographs, cylindrical bronchiectasis, generalized disease, and right cranial lung lobe involvement were most common. (avma.org)
  • High resolution chest CT scans showed heterogeneous air trapping, cylindrical bronchiectasis, and patchy ground-glass opacities. (cdc.gov)
  • Bronchiectasis is a chronic suppurative lung disease often characterised by airflow obstruction and hyperinflation, and leading to decreased exercise tolerance and reduced health status. (bmj.com)
  • Bronchiectasis is a chronic (often suppurative) lung disease not traditionally included in the definition of COPD, but also characterised by airflow obstruction and symptoms including cough, sputum production, wheeze, dyspnoea, and decreased exercise tolerance. (bmj.com)
  • Bronchiectasis is a common chronic lung disease characterized by recurrent infections due to defective mucus clearance from the airways and can progress to chronic respiratory failure and death. (biomedcentral.com)
  • The 1966 examination showed that he had a condition called bronchiectasis, due to the prior lung disease. (wikipedia.org)
  • Among clinical characteristics, a history of COPD, emphysema, and bronchiectasis were significant predictors for Pi*ZZ, whereas a history of asthma, cough and phlegm were predictors of not carrying the genotype Pi*ZZ. (biomedcentral.com)
  • Conclusion: Pulmonary manifestations including pulmonary fibrosis, emphysema, and bronchiectasis are observed in MPA. (nsw.gov.au)
  • The specificity of HRCT for bronchial asthma is limited by the similarity of its changes to those of other diseases, such as bronchiectasis, chronic bronchitis, emphysema, and bronchopulmonary aspergillosis. (medscape.com)
  • Bronchiectasis is a widely prevalent airway disease characterized by airway dilatation and recurrent infections, that can lead to respiratory failure in severe cases. (biomedcentral.com)
  • There was a significantly lower level of Lipoxin A4 (LXA4) in severe bronchiectasis. (ed.ac.uk)
  • The most popular test for bronchiectasis diagnosis is a chest computed tomography (CT) scan because a chest X-ray does not give enough information. (medanta.org)
  • Emphasizing the role of multi-detector computed tomography chest in the etiological diagnosis of pulmonary bronchiectasis. (jclmm.com)
  • Although she had no symptoms, chest computed tomography findings showed centrilobular nodules and bronchiectasis. (cdc.gov)
  • Objectives: To determine the frequency and geographic variability that exists in a sensitization pattern to common and specific allergens, including house dust mite and fungi, and to correlate such patterns to airway immune-inflammatory status and clinical outcomes in bronchiectasis. (a-star.edu.sg)
  • The aim of our study was to evaluate the effectiveness of PD, percussion, CT, and huffing in subjects with bronchiectasis and assess the quantity and quality of bronchial mucus produced (measurement of wet and dry weight and determination of viscoelastic properties). (rcjournal.com)
  • Bronchiectasis is characterized by abnormal, permanent dilation of the bronchi, 1 which results in chronic cough, mucus production in the airways, and recurrent pulmonary infections. (rcjournal.com)
  • Due to the chronic, progressive nature of bronchiectasis, it is important to establish effective therapeutic strategies 3 to facilitate mucus clearance and decrease the retention of pulmonary secretions. (rcjournal.com)
  • Bronchiectasis is a chronic respiratory condition characterized by the widening and inflammation of the bronchial tubes, which can lead to excessive mucus buildup and recurrent infections. (ayurvedguru.com)
  • A persistent cough that produces large amounts of mucus (sputum) is the most common symptom of bronchiectasis. (ayurvedguru.com)
  • Healthcare professionals manage infections and clean mucus to treat bronchiectasis. (medanta.org)
  • PR is effective in improving exercise tolerance in bronchiectasis but there is no additional advantage of simultaneous IMT. (bmj.com)
  • Bronchiectasis is a chronic respiratory disease that causes persistent cough, sputum production and recurrent chest infections. (ersjournals.com)
  • Individuals with bronchiectasis are prone to recurrent lung infections, which can lead to increased cough and worsened symptoms. (ayurvedguru.com)
  • Bronchiectasis is frequently associated (up to 30%) with chronic inflammatory rheumatic diseases and leads to lower respiratory tract infections. (biomedcentral.com)
  • Median duration of clinical signs prior to diagnosis of bronchiectasis was 9 months (range, 1 day to 10 years). (avma.org)
  • The usefulness of imaging signs for the diagnosis of PH and of coronary lesions by using chest HRCT examination was demonstrated, underlying the role of modern diagnostic and treatment strategies in certain bronchiectasis patient sub-populations. (cnaa.md)
  • Bronchiectasis was the most common cause of false diagnosis, followed by hydatid disease, malignancy, and aspergillosis. (tgcd.org.tr)
  • The etiology of bronchiectasis varies geographically, but there is a lack of published data examining its etiology specifically within the Middle Eastern population. (biomedcentral.com)
  • Data on the coexistence of bronchiectasis with these diseases is lacking but is necessary to help inform management. (ersjournals.com)
  • Introduction: Bronchiectasis is one of the common chronic respiratory diseases and associated with respiratory morbidity and mortality. (jclmm.com)
  • Conclusions: These findings suggest predominant ventilator-induced lung damage in better ventilated areas (i.e., nondependent regions). (elsevierpure.com)
  • Measurements and Main Results: A high frequency of sensitization to multiple allergens was detected in bronchiectasis, exceeding that in a comparator cohort with allergic rhinitis (n = 149). (a-star.edu.sg)
  • Poor to no correlation was noted with the variables of cavity, malignant tumour, and bronchiectasis, but the prevalence of these conditions in our cohort was low. (sun.ac.za)
  • We conducted a retrospective analysis of our bronchiectasis patient registry, extracting clinical and demographic characteristics from electronic medical records. (biomedcentral.com)
  • Bronchiectasis is an increasing clinical problem, but multiple recent clinical trials have failed to reach their primary end-point. (ersjournals.com)
  • In this study, we conducted a systematic review of the end-points used in bronchiectasis clinical trials with the goal of identifying the most widely used end-points, their definitions and responsiveness, and of identifying research priorities for optimising pharmacotherapy trials. (ersjournals.com)
  • HRCT score in bronchiectasis: correlation with pulmonary function tests and pulmonary artery pressure. (jclmm.com)
  • Conclusions Our results confirm the viability of this diagnostic system for genotyping AATD conducted simultaneously in different countries. (gencat.cat)
  • Further characterisation of these lipids and understanding the interplay of anti and pro-inflammatory lipid mediators could lead to the development of novel anti-inflammatory therapies for bronchiectasis. (ed.ac.uk)
  • Objective -To determine demographic, clinical, and radiographic features of bronchiectasis in dogs. (avma.org)
  • Air cysts, bronchiectasis, and the percentage of normal and abnormal tissue were quantified for each segment and correlated to the duration and variables of mechanical ventilation. (elsevierpure.com)