• Cardiovascular risk factors, including hypertension, hyperlipidaemia, obesity and smoking, were studied as well as degree of blood glucose control. (who.int)
  • Treatment of standard risk factors, such as hyperglycemia, hypertension, and hyperlipidemia, mitigates some of the higher CVD risk, but residual increased CVD risk remains even with good control of these risk factors. (nih.gov)
  • High density lipoprotein turnover in patients with hypertension. (nhri.edu.tw)
  • Platelets have a "key role" in atherogenesis and its thrombotic complications in subjects with DM [ 3 ], and the concomitant presence of multiple "classical" cardiovascular risk factors (arterial hypertension, cigarette smoking, and hyperlipidemia) in diabetic subjects contributes to enhanced atherothrombotic risk. (hindawi.com)
  • Diabetic patients often combined with metabolic disorders like hypertension, and hyperlipidemia, easily lead to cardio-cerebrovascular diseases like coronary heart disease, which is a risk factor leading to death [ 2 ]. (biomedcentral.com)
  • Routine screening for complications and co-morbidities of diabetes will identify a small number of adolescents who are positive for microalbuminuria, hypertension, and hyperlipidemia. (chop.edu)
  • There are high chances of gout developing into other complication like hyperuricemia, hypertension, hyperlipidemia, coronary disease, diabetes, kidney stone and hardening of arteries of coronary heart disease. (crypto.com.my)
  • Hypertension (high blood pressure) with type 1 and 2 can worsen them. (thehealthsite.com)
  • Hypertension or increased blood pressure may occur in diabetics because of the impact of diabetes on the walls of the arteries and the fluid balance. (thehealthsite.com)
  • The early detection and treatment of hypertension and diabetes can prevent serious complications. (thehealthsite.com)
  • The micro and macrovascular complications of Type 2 diabetes mellitus are influenced by several well described cardiovascular risk factors such as hyperglycaemia, hypertension, hyperlipidaemia, and smoking alongside age, sex, and diabetes duration. (emjreviews.com)
  • This is caused by the impact of cardiovascular risk factors such as hypertension, hyperlipidaemia, hyperglycaemia, and increased risk of thrombosis besides the influence of age, sex, and diabetes duration. (emjreviews.com)
  • [ 1 ] Nevertheless, a majority of the cases of diabetic nephropathy presents with proteinuria, which progressively gets worse as the disease progresses, and is almost uniformly associated with hypertension. (medscape.com)
  • The patient's past diagnoses at the time of infection included type 2 diabetes mellitus, lupus, hypertension, hyperlipidemia, sleep apnea, and coronary artery disease. (cdc.gov)
  • Factors that may contribute to this greater platelet reactivity are not completely elucidated and include metabolic abnormalities as hyperglycemia, hyperlipidemia, insulin resistance, and conditions as oxidative stress, inflammation, and endothelial dysfunction [ 3 ]. (hindawi.com)
  • An optimal method of addressing diabetes comprises of lifestyle and medical interventions which reduce hyperglycemia thereby decreasing the likelihood of developing the associated diabetic complications [ 3 - 5 ]. (jabonline.in)
  • More recently, the close association of diabetes and cardiovascular complications are ascertained because of the effect of hyperglycemia on the blood lipid profiles. (jabonline.in)
  • High glucose affected the expression level of cell-bound perlecan, angiogenesis-associated cytokines, and the matrix degradation on the cells, implying that hyperglycemia influences vessel formation during placentation. (hindawi.com)
  • Moreover, if hyperglycemia - i.e. abnormally high blood sugar - persists for a long while, small blood vessels in the kidneys, nerves, and eyes may become severely damaged. (regulatemyhealth.com)
  • In the long-term study, the EX-ABD-AFF could significantly reverse the obesity-related metabolic complications (hyperglycemia, hyperlipidemia, and hepatic steatosis) and, more-over, improve cognitive deficits. (gnu.ac.kr)
  • Diabetes mellitus (DM) is associated with macrovascular and microvascular complications (coronary artery disease, ischemic stroke, peripheral arterial disease, nephropathy, and retinopathy) [ 1 , 2 ]. (hindawi.com)
  • The most common form of diabetic eye disease is diabetic retinopathy, in which damage to tiny blood vessels, a result of high blood sugar, can lead to blindness. (swhcoronaregional.com)
  • In either case, it can significantly increase the chances of developing heart conditions or conditions like stroke as well as the risk of developing other complications like renal or eye related conditions like nephropathy, retinopathy, etc. (thehealthsite.com)
  • Diabetic retinopathy (DR) is a sight threatening complication of systemic diabetes mellitus that results from damage to the blood vessels of the retina. (institut-vision.org)
  • Metabolic complications include insulin resistance, high metabolic rate, and uncontrolled lipid levels such as hypertriglyceridemia, low HDL, and high LDL. (wikipedia.org)
  • Insulin resistance and abnormal electrocardiograms in patients with high blood pressure. (nhri.edu.tw)
  • 23 ] showed that the effects of IOP on restoration of insulin resistance in streptozotocin-induced type II diabetic mice might involve in the PI3K/Akt signal pathway, which showed significant effect in the dose of 900 mg/kg. (biomedcentral.com)
  • Alternanthera sessilis red ethyl acetate fraction exhibits antidiabetic potential on obese type 2 diabetic rats ") report that, despite their inability to identify active compounds, they observed that ethyl acetate fraction of Alternanthera sessilis ameliorated T2D via increased insulin content and decreased insulin resistance. (hindawi.com)
  • Early management of diabetes with strict control of blood glucose levels reduces microalbuminuria and progression to diabetic nephropathy. (fortuneonline.org)
  • Although diabetic patients are predisposed to nephropathy, it should be noted that medical management, including therapeutic and dietary follow-up, improves the metabolic health of these patients and slows the development of long-term complications. (fortuneonline.org)
  • Diabetes is the leading cause of end-stage renal disease (ESRD) worldwide, with approximately 40-60% of people with type 2 diabetes developing diabetic nephropathy (DN) after 10-15 years of diabetes progression [5,6]. (fortuneonline.org)
  • Currently, diabetic nephropathy is the leading cause of chronic kidney disease in the United States and other Western societies. (medscape.com)
  • Generally, diabetic nephropathy is considered after a routine urinalysis and screening for microalbuminuria in the setting of diabetes. (medscape.com)
  • Good evidence suggests that early treatment delays or prevents the onset of diabetic nephropathy or diabetic kidney disease. (medscape.com)
  • Regular outpatient follow-up is key in managing diabetic nephropathy successfully. (medscape.com)
  • Recently, attention has been called to atypical presentations of diabetic nephropathy with dissociation of proteinuria from reduced kidney function. (medscape.com)
  • Also noted is that microalbuminuria is not always predictive of diabetic nephropathy. (medscape.com)
  • Three major histologic changes occur in the glomeruli of persons with diabetic nephropathy. (medscape.com)
  • The earliest morphologic abnormality in diabetic nephropathy is the thickening of the GBM and expansion of the mesangium due to accumulation of extracellular matrix. (medscape.com)
  • The image below is a simple schema for the pathogenesis of diabetic nephropathy. (medscape.com)
  • Fasting blood sugar (FBS), triglyceride (TG), total cholesterol (TC), low and high density lipoprotein (LDL, HDL), glycated haemoglobin HbA(Ic) and serum insulin were measured before and after vitamin C consumption and the results were analyzed. (amrita.edu)
  • [ 203 ] Orlistat has been shown to be effective at producing modest weight loss in diabetics, can prevent progression to diabetes in the 'at risk' population and can lead to some improvement in CV risk factors, including cholesterol, systolic and diastolic blood pressure. (medscape.com)
  • About half of the studied T2DM patients have high serum cholesterol level (52.5%), while 22.5% had low serum HDL- C levels and 39.2% had high serum triglyceride level, most of patients had serum LDL-C levels above normal range (67.5%), so the common patterns of dyslipidemia in this study were LDL-C followed by cholesterol. (heraldopenaccess.us)
  • High prevalence of dyslipidemia among type 2 diabetes mellitus in Mukalla city were observed and so the common patterns of dyslipidemia is LDL-C followed by cholesterol. (heraldopenaccess.us)
  • Other factors that may increase the risk of diabetes include high blood pressure and hyperlipidemia (elevated cholesterol). (swhcoronaregional.com)
  • Hyperlipidemia is a condition characterized by increased levels of bad cholesterol and triglycerides (fats) in the blood. (netmeds.com)
  • I think your doctor meant hyperlipidemia nutrition therapy which means you have normal or slightly increased cholesterol and high triglycerides (VLDL). (dietitian.com)
  • Saturated fat, trans fat and high-fat foods will make your cholesterol go higher. (dietitian.com)
  • In most cases, the acetyl CoA is converted to cholesterol - in type 2 diabetic patients - which may bring about heart disease and hyperlipidemia in these patients. (regulatemyhealth.com)
  • Fatty cuts of meat, fat, animal organs are prohibited for CHD patients, who should also quit smoking and drink a limited amount of alcohol.Therefore,during ICP usage,high-cholesterol food should be taken as little as possible. (com.ng)
  • HDL-C: high-density lipoprotein cholesterol. (emjreviews.com)
  • Eating foods high in soluble fiber as part of a low-fat, low-cholesterol diet can help prevent heart disease. (medlineplus.gov)
  • Taking blond psyllium by mouth reduces low density lipoprotein (LDL or "bad") cholesterol in people with mild to moderate high cholesterol. (medlineplus.gov)
  • Aim: The objectives of this study were to evaluate the levels of glucose, cholesterol, protein and albumin in saliva, and to correlate the levels of glucose of the saliva to oral health and blood glucose of diabetic and non-diabetic children. (bvsalud.org)
  • Thus, the objectives of this study were to evaluate the levels of glucose, cholesterol, protein and albumin in saliva, and to correlate the levels of glucose of the saliva to oral health and blood glucose of diabetic and non-diabetic children thereby analyzing whether saliva-based glucose testing can be an effective alternative to blood-based glucose testing in children. (bvsalud.org)
  • In the general population, evidence is less strong for a benefit from lowering elevated TG and increasing low high-density lipoprotein cholesterol (HDL-C) levels. (msdmanuals.com)
  • This system does not take into account specific lipoprotein abnormalities (eg, low HDL-C or high LDL-C) that may contribute to disease despite normal cholesterol and TG levels. (msdmanuals.com)
  • A colleague of mine related the tale of a pt, a young man with Type 1 diabetes, who went into diabetic ketoacidosis (DKA) and didn't get appropriate treatment. (endofshiftreport.com)
  • Ketoacidosis - i.e. acidosis with an accumulation of ketone bodies which primarily occurs in diabetes mellitus - is another severe complication to watch out for. (regulatemyhealth.com)
  • Daily feeding of Nelumbo nucifera leaf powder for 21 days resulted significant decrease in the blood glucose levels of alloxan-induced diabetic rats. (scirp.org)
  • In preclinical studies, Nicotinamide Mononucleotide work on mice has proved to be handy in cellular biochemical activities, management of Alzheimer's disease, age-related diabetes, complications that arise from obesity, and cardioprotection. (articlecity.com)
  • [ 4 ] Conversely, it is crucial to recognize that patients with chronic physical disability have a higher incidence of vascular disease development, due to a greater incidence of obesity and metabolic syndrome (which herald diabetes, hypercholesterolemia, and hypertriglyceridemia). (medscape.com)
  • In pregnancy as mentioned earlier the lipid concentration in blood increases, if the concentration of the lipids in the blood is not controlled it results in the increase in the concentration of the lipid in the perinatals and may be leads obesity and/or hyperlipidemia [ 25 - 31 ]. (omicsonline.org)
  • The mechanisms linking these risk factors with disease manifestation of micro and macrovascular complications are based on gene-environmental interactions, where a less healthy lifestyle, for example smoking, lack of physical exercise, or unhealthy eating habits, result in obesity. (emjreviews.com)
  • Diabetes mellitus (DM) is associated with macrovascular and microvascular complications. (hindawi.com)
  • However, current oral antidiabetic agents using orthodox medicine have unmet efficacy and undesirable side effects in patients, leading to the development of microvascular and macrovascular complications. (hindawi.com)
  • These complications usually affect large blood vessels and are collectively known as "macrovascular" complications. (regulatemyhealth.com)
  • The results showed that the oral administration of IOP in high dose (1.2 g/kg) can significantly reduce the blood glucose with 31% reduction comparing with the diabetic model and relieve dyslipidemia in diabetic mice. (biomedcentral.com)
  • The prevalence of dyslipidemia in type 2 diabetic patients was 85%, prevalence of dyslipidemia in males was 86% while in females was 84% but the difference was not significant (P-value 0.4). (heraldopenaccess.us)
  • Altered function of the hypothalamic-pituitary-adrenal (HPA) axis in type 2 diabetic patients, a condition preceded by pre-diabetes, has been shown to increase the risk of depression as well as cause downstream effects resulting in upregulation of gluconeogenesis and dyslipidemia. (researchsquare.com)
  • However, dysregulation of the HPA axis in T2DM has been shown to worsen further the hyperglycaemic state causing hyperlipidemia and dyslipidemia as well as increase the risk of depression in diabetic patients (8, 13-16). (researchsquare.com)
  • ABSTRACT To determine frequency of cardiovascular risk factors in Saudi and non-Saudi diabetics, we studied patients attending King Abdulaziz University Hospital for follow-up in the period January 1997 to December 2001. (who.int)
  • The study tion was used to study the correlation of group comprised 1155 diabetic patients, all different cardiovascular risk factors to age. (who.int)
  • [ 85 ] A later 1-year, multicenter RCT to assess the effect of orlistat and hypocaloric diet in Type 2 diabetics on metformin showed that orlistat-treated patients lost significantly more weight at 1 year compared with placebo (4.7 ± 0.3 kg vs 1.8 ± 0.3 kg, respectively). (medscape.com)
  • The role of chronic administration of antiplatelet drugs in primary prevention of arterial vascular events is known to be less clear than in secondary prevention, and, also in diabetic patients, the decision to give primary prophylaxis should be taken on an individual-patient basis, after a careful evaluation of the balance between the expected benefits and the risk of major bleedings. (hindawi.com)
  • Although, currently, treatment has proven useful in reducing vascular events, diabetic patients continue to have a higher risk of adverse cardiovascular events compared with those in nondiabetic patients. (hindawi.com)
  • This paper reviews the role of currently available antiplatelet drugs in primary and secondary prevention of vascular events in diabetic patients and the limitations of these drugs, and it discusses the role of novel and more potent antiplatelets and of new agents currently under clinical development. (hindawi.com)
  • However, although the currently available treatments have proven to be useful in reducing ischemic events, diabetic patients continue to have a higher risk of adverse events compared with those in non-diabetic patients. (hindawi.com)
  • The role of novel and more potent antiplatelet strategies, currently under clinical development, seems attractive in diabetic patients. (hindawi.com)
  • Cardiovascular (CV) diseases are the leading cause of morbidity and mortality in diabetic patients. (hindawi.com)
  • This paper aimed to measure miR-222-3p expression in sera of PCOS patients and to explore its clinical value on PCOS diagnosis and prediction of diabetic and cardiovascular complications. (biomedcentral.com)
  • It is estimated that the diabetic patients worldwide are up to 463 million at present [ 1 ]. (biomedcentral.com)
  • Patients with diabetes mellitus are at high risk of cardiovascular events because of abnormal lipid levels status. (heraldopenaccess.us)
  • A Cross-sectional study was conducted in a randomly selected eligible patients from the diabetic registry of the AL Noor Charity Center (ACC), Mukalla city in eastern Yemen during the period from May-July 2017. (heraldopenaccess.us)
  • A Web-based interactive GIS system was designed to serve as an electronic medical file for diabetic patients retrieving data from medical files by trained registrars. (jmir.org)
  • Economic reports give accurate cost estimation of different services given to diabetic patients, such as the annual insulin cost per patient for type 1, type 2, and gestational diabetes, which are 1155 SR (US $308), 1406 SR (US $375), and 1002 SR (US $267), respectively. (jmir.org)
  • The aim of this study was to compare the glomerular filtration rate of two groups of diabetic patients: those under medical supervision and those who are not under supervision and taking no treatment with normal individuals. (fortuneonline.org)
  • The sample consisted of 99 participants, distributed as follows: 36.4% were diabetics under treatment and medically monitored, 32.3% were naïve diabetics not medically monitored and 31.3% were healthy patients. (fortuneonline.org)
  • We identified 98,819 patients who were diagnosed with hyperlipidemia between January 1, 2007, and December 31, 2013, and had at least 1 triglyceride measurement annually for 4 consecutive years from the Chang Gung Research Database in Taiwan. (lww.com)
  • Subgroup analysis showed that this association was more pronounced among the patients with a higher neutrophil-to-lymphocyte ratio ( P for trend = 0.022). (lww.com)
  • Background: The healing of foot wounds in patients with diabetes mellitus is frequently complicated by critical limb threatening ischemia (neuro-ischemic diabetic foot syndrome, DFS). (mdpi.com)
  • This study was to explore the effect of hyperlipidemia on the incidence of cardio-cerebrovascular diseases in patients with type 2 diabetes. (biomedcentral.com)
  • The incidence of cardio-cerebrovascular diseases between diabetes combined with hyperlipidemia group (195 patients) and diabetes group (200 patients) were made a comparison. (biomedcentral.com)
  • Multivariable Cox's proportional hazards regression model was used to analyze the effect of hyperlipidemia on the incidence of cardio-cerebrovascular diseases in patients with type 2 diabetes. (biomedcentral.com)
  • Population attributable risk percent of all-cause mortality and total cardiovascular events in patients with type 2 diabetes combined with hyperlipidemia was 9.6% and 26.8%, respectively. (biomedcentral.com)
  • Hyperlipidemia may promote vascular endothelial injury, increasing the risk of cardio-cerebrovascular diseases in patients with type 2 diabetes. (biomedcentral.com)
  • By the year 2035 the number of diabetic patients is expected to increase by 55% to 600 million. (biomedcentral.com)
  • Diabetes complications, cardio-cerebrovascular diseases are the common factors that cause the death of patients. (biomedcentral.com)
  • An epidemiological survey showed the incidence of acute stroke in patients with high hyper-sensitive C-reactive protein (hs-CRP) level was two times higher than healthy people and myocardial infarction was three times higher [ 9 ]. (biomedcentral.com)
  • Three hundred ninety five patients with type 2 diabetes in our hospital from January 2012 to January 2016 were divided into diabetes combined with hyperlipidemia group (195 patients) and diabetes group (200 patients). (biomedcentral.com)
  • In addition, the clinical care of diabetic adolescents requires screening these vulnerable patients for depression and eating disorders. (chop.edu)
  • Consensus guidelines from the Joint National Committee on the Prevention, Detection, Evaluation, and Treatment of High Blood Pressure, the American Diabetes Association (ADA) and the National Kidney Foundation (NKF) recommend a blood pressure goal of less than 130/80 mm Hg in patients with diabetes. (thehealthsite.com)
  • Patients with CKD are at a high risk of cardiovascular disease and mortality and are associated with increased treatment costs [ 2 ]. (medsci.org)
  • While T2DM is often associated with macro-and microvascular complications, studies indicate that poor management of everyday stress in diabetic patients is associated with increased risk of depression and anxiety (5-7). (researchsquare.com)
  • This is said to be due to the constant activation of the hypothalamic-pituitary-adrenal (HPA) axis observed in type 2 diabetic patients (8). (researchsquare.com)
  • The patients with diabetes recruited have generally been high-riskpatients and in most cases, with a previous cardiovascular disease (CVD) manifestation. (emjreviews.com)
  • The number of diabetic patients has increased dramatically over the past two decades, from an estimated 30 million people in 1985 to 463 million people in 2020. (healthpediaindia.com)
  • If the current trend will follow then the number of diabetic patients will increase to 642 million by the year 2040 . (healthpediaindia.com)
  • By the 1950s, kidney disease was clearly recognized as a common complication of diabetes, with as many as 50% of patients with diabetes of more than 20 years having this complication. (medscape.com)
  • It is also one of the most significant long-term complications in terms of morbidity and mortality for individual patients with diabetes. (medscape.com)
  • Nonsteroidal anti-inflammatory drugs are the first-line drugs for these patients, but their utility for the elderly and for those with certain chronic conditions is limited, owing to the high risk of bleeding and kidney damage. (medscape.com)
  • Il s'agit d'une étude transversale, monocentrique et descriptive, durant 12 mois, incluant les patients âgés d'au moins 18 ans admis en réanimation polyvalente pour un sepsis ou choc septique. (bvsalud.org)
  • Patients with severe malaria are at risk for life-threatening complications including: renal failure, acute respiratory distress syndrome (ARDS), severe hemolytic anemia, and cerebral malaria. (cdc.gov)
  • The renal vasculature typically displays evidence of atherosclerosis, usually due to concomitant hyperlipidemia and hypertensive arteriosclerosis. (medscape.com)
  • Lorcaserin has been shown to have a moderate effect on weight loss and glycemic control in the diabetic population, although questions remain regarding its long-term safety profile. (medscape.com)
  • They are prone to certain complications and evidence emerged in the 1990's supporting the benefits of glycemic control as well as control of blood pressure and lipid levels in the prevention or delay in onset and severity of diabetes complications [10,11]. (heraldopenaccess.us)
  • Glycemic control remains the major clinical objective in management of diabetes whereas long-term management targets in prevention of micro vascular and macro vascular complications. (heraldopenaccess.us)
  • Diabetes mellitus is a common secondary cause of hyperlipidemia, particularly if glycemic control is poor, which in-turn is an important risk factor for atherosclerosis and coronary heart disease [12,13]. (heraldopenaccess.us)
  • These complications, therefore, are collectively referred to as "microvascular" complications. (regulatemyhealth.com)
  • 0.05) decreased blood glucose level up to 44% and 33% respectively where the higher percentage of Nelumbo nucifera powder was found to be exerted to the more prominent effects in lowering the blood glucose level. (scirp.org)
  • Background & objective: Diabetes mellitus is one of the most common metabolic disorders that causes micro- and macro-vascular complications. (amrita.edu)
  • The present study investigated hypoglycemic effects with normal and diabetic rats being administrated orally without or with ECE at 200 and 800 mg/kg for 15 days. (mdpi.com)
  • In rats, hyperlipidemia was induced by feeding High Fat Diet (Lab diet: Dalda: Coconut oil = 4:3:1) and type 2 diabetes was built inside by injecting Alloxan. (scirp.org)
  • Sprague Dawley Rats were randomly divided into non-prediabetic group (NPD) and pre-diabetic group (PD) (n=6, per group) over a 20-week induction period and a further 12-week experimental period to get 32 weeks. (researchsquare.com)
  • In conclusion, EE has the potential to be an important therapeutic component in the treatment of diabetes and its complications. (jabonline.in)
  • In this special issue, we aimed to gather together updated information reflecting the considerable progress in basic and clinical research into CAM for diabetes and its complications. (hindawi.com)
  • Lipolysis is a process of breaking down of triglycerides to glycerol and fatty acids, the process is done by hydrolysis by inducing some hormones like epinephrine, nor-epinephrine, cortisol, testosterone, etc. to release the compounds like High density lipoproteins (HDL), Low density lipoproteins (LDL) and Very low density lipoproteins (VLDL) [ 12 - 18 ]. (omicsonline.org)
  • By inhibiting the production of LDL and VLDL the risk factors for the hyperlipidemia can be controlled, Bile acid sequestrants like Cholestyramine, Colestipol and Colesevelam are used to regulate high serum levels by binding the bile acid which is secreting from liver to metabolize the triglycerides [ 20 - 24 ]. (omicsonline.org)
  • I haven't heard a nutrition therapy for high triglycerides called this in years as the American Heart Association and the National Institute of Health replaced these types. (dietitian.com)
  • If your diabetes is not well controlled, it may be the cause for your high triglycerides. (dietitian.com)
  • Where can I find a dietitian who works with people who have high triglycerides? (dietitian.com)
  • In addition to atherosclerotic disease, both diastolic and systolic diabetic cardiomyopathies are associated with significant morbidity and mortality. (nih.gov)
  • Based on the recent survey report conducted by Indus Health Plus, it was found that 26 per cent of the people tested had high blood pressure out of which 13 per cent had systolic blood pressure above 140 mm Hg. (thehealthsite.com)
  • Male sex, higher severity of diabetes (indicated by use of insulin and oral diabetes treatments versus pills alone or use of pills alone versus no treatment), higher average systolic blood pressure, and higher hemoglobin A1c are additional factors to be considered. (institut-vision.org)
  • Adolescent Diabetes 2019 highlights the theme "Novel Insights On Pediatrics and Adolescent Diabetes" Which emphasis on the latest advancements in prevention and treatment cure of various metabolic diseases which may be due to diabetic and endocrine complications and provides robust discussions on methods and strategies related to diagnosis , prevention and management of metabolic disorders as well as explore new ideas and concepts for treatment of Endocrine Complications. (endocrineconferences.com)
  • Diabetic peripheral neuropathy (DPN) is a major complication of diabetes that affects predominantly sensory and autonomic axons. (nature.com)
  • Increased consumption of high caloric diet and physical inactivity coincided with the increased prevalence of diabetes and pre-diabetes (3, 4). (researchsquare.com)
  • A common and problematic complication of diabetes is foot ulcers, which can generally be prevented through self-examination and proper foot care. (swhcoronaregional.com)
  • To identify, from the scientific literature, the main self- i t h D care deficits present in elderly people with diabetic foot ulcers, based on Orem's self-care deficit theory. (bvsalud.org)
  • 9%), type and duration of DM were also diabetics and non-diabetics [ 6-10 ]. (who.int)
  • The National Institute of Diabetes and Digestive and Kidney Disorders (NIDDK) intends to promote a new initiative by publishing a Notice of Funding Opportunity (NOFO) to solicit applications for research on the cardiovascular complications of type 1 diabetes (T1D) as part of the NIH Cardiovascular Repository for T1D (CaRe-T1D). (nih.gov)
  • a multicenter RCT was conducted in Type 2 diabetics, who were clinically stable on a SU, to compare the effect of a hypocaloric diet plus either orlistat or placebo. (medscape.com)
  • The BLOOM-DM study was a 1-year RCT in Type 2 diabetics taking metformin or SU, or both, comparing placebo with 10 mg lorcaserin daily (q.d.) versus lorcaserin 10 mg twice daily (b.i.d. (medscape.com)
  • Having prediabetes puts you at a higher risk of getting type 2 diabetes. (medicospace.com)
  • I am a type 2 diabetic and recovering from a stroke . (dietitian.com)
  • In high-income countries, type 2 diabetes accounted for 85%~ 95% of diabetes, which might be higher in middle-income and low-income countries. (biomedcentral.com)
  • Methods: 32 children with type 1 diabetes mellitus formed the study group (DC) and 32 non-diabetic children formed the control group (ND). (bvsalud.org)
  • Clinical presentations of AGL are similar to other lipodystrophies, including metabolic complications and hypoleptinemia. (wikipedia.org)
  • Chronic kidney disease (CKD) is a chronic complication of diabetes, characterized by the presence of pathological quantities of urine albumin excretion and/or accompanied by a gradual deterioration in the glomerular filtration rate (GFR). (medsci.org)
  • Moreover, the concomitant presence of multiple "classical" cardiovascular risk factors in diabetic subjects contributes to enhanced atherothrombotic risk. (hindawi.com)
  • Because of additive effects of hyperglycaemia and hyperlipidaemia for cardiovascular diseases, lipid abnormalities should be evaluated in diabetes. (amrita.edu)
  • During recent years three new trials (EMPA-REG, LEADER, and SUSTAIN-6) have shown that treatment of hyperglycaemia with new anti-diabetic drugs has been able to reduce a composite cardiovascular endpoint. (emjreviews.com)
  • The pathophysiology of atherosclerosis, cardiomyopathy, endothelial dysfunction, and cardiac autonomic neuropathy in T1D is poorly understood and no therapies are approved to prevent or treat these common, deadly complications of T1D. (nih.gov)
  • These results suggest that EQ treatment may exert a neuroprotective effect in diabetic neuropathy. (nature.com)
  • The prevention of diabetes-induced mtDNA deletions may be a potential mechanism of the neuroprotective effects of EQ in diabetic neuropathy. (nature.com)
  • However, we still do not have a clear understanding of whether mtDNA mutations and subsequent mitochondrial dysfunction is involved in diabetic neuropathy. (nature.com)
  • S. H. Kim and coworkers (" Citrus junos Tanaka peel extract exerts antidiabetic effects via AMPK and PPAR- both in vitro and in vivo in mice fed a high-fat diet ") indicate that the ethanol extract of the peel of Citrus junos in vitro stimulates glucose uptake in C2C12 myotube cells. (hindawi.com)
  • It is used to treat hyperlipidemia (high blood lipid levels) in addition to proper diet, exercise and lifestyle changes. (netmeds.com)
  • For the hypolipidemic activity investigation, the selected animals are normally fed high fat diet to originate hyperlipidemia inside those animals. (scirp.org)
  • Furthermore, in high-fat diet (HFD)-fed obese mice model, the EX-ABD-AFF could provide significant hypoglycemic effects for over 12 days, accompanied by a reduction of body weight. (gnu.ac.kr)
  • This study investigated the activity of the HPA axis in selected markers of glucose handling, and the stress response relative to components of the HPA axis in a diet-induced pre-diabetic rat model. (researchsquare.com)
  • It has been shown that MPV is significantly higher in diabetic populations [ 5 ]. (hindawi.com)
  • The glomerular filtration rate was significantly lower in the diabetic naïve group (65.88±23.19 ml/ min/1.73m2). (fortuneonline.org)
  • and the risk is significantly greater in African Americans, and slightly higher in Hispanics and Native Americans as well, compared to whites. (statpearls.com)
  • This study aims to evaluate the hypoglycemic activity and investigate the molecular mechanism of I. obliquus polysaccharide (IOP) in streptozotocin (STZ)-induced diabetic mice using metabolomics based on UPLC-Q-Exactive-MS method. (biomedcentral.com)
  • In the studies of hypoglycemic effects, the subjected animals are being made diabetic using alloxan, streptozotocin (STZ) etc introducing inside injecting intraperitoneally (IP) or intravenously (IV). (scirp.org)
  • The history may reveal a recent episode of dietary indiscretion, toxin ingestion (e.g., chocolate or high-fat food) or drug administration. (ivis.org)
  • The analysis results of multivariable Cox's proportional hazards regression model showed that the risks of myocardial infarction and total cardiovascular events in diabetes combined with hyperlipidemia group were respectively 1.54 times (95% CI 1.13-2.07) and 1.68 times (95% CI 1.23-2.24) higher than those in diabetes group. (biomedcentral.com)
  • In vivo studies on the diabetic complications known as hypercholesterolemia and hypertriacylglycerolemia in diabetic rat models also revealed significant improvements in serum/liver levels as well as a notable increase in the activities of enzymatic and nonenzymatic antioxidant levels. (jabonline.in)
  • Prevention and control of iron deficiency anemia among high risk groups. (who.int)
  • Prevention of vitamin A deficiency and its complications in the high risk groups (preschool age children 6 M.- 6 Y., pregnant and lactating women). (who.int)
  • People with diabetes are at risk for complications that may affect the eyes, kidneys, nerves and circulatory system. (swhcoronaregional.com)
  • A glycohemoglobin blood test (A1c) will tell your doctor what your blood glucose control has been over the last 4 months and research has found that this test is the best indicator of reduced complications from diabetes i.e. eyes, feet, kidneys or nerves. (dietitian.com)
  • The search for studies was performed in Jan- l d e r l y P uary 2022, using the descriptors "diabetic foot", "self-care," and "aged. (bvsalud.org)
  • In this research, we explored the feasibility of applying the ABD-AFF fusion strategy to exendin-4 (EX), a clinically available anti-diabetic peptide possessing a short plasma half-life. (gnu.ac.kr)
  • Pregnant women with diabetes are a higher risk for developing DR. If gestational diabetes develops, the patient may be at higher risk of developing diabetes with age. (institut-vision.org)
  • IOP has predominant hyperglycemic effect on STZ-induced diabetic mice via ameliorating serum profiling. (biomedcentral.com)
  • For example, in familial combined hyperlipidemia, expression may occur only in the presence of significant secondary causes. (msdmanuals.com)
  • For example, high HDL-C levels caused by some genetic disorders may not be associated with a lower risk of cardiovascular disorders, and low HDL-C levels caused by some genetic disorders may not be associated with an increased risk of cardiovascular disorders. (msdmanuals.com)
  • These proteins then hinder the normal signal transduction pathway thereby generating reactive oxygen species and lead to several oxidative stress-induced complications [ 8 ]. (jabonline.in)
  • Bonus: when your blood sugar is insanely high, your kidneys can try to compensate by squeezing sugar directly out through your blood filters, which lets you piss away the dangerously gooey stuff… but rips holes in your filters, essentially. (endofshiftreport.com)
  • And as soon as their blood thins out a little, their kidneys dump all that new water in an attempt to flush out the sugar, further ripping themselves to shreds… which is why undiagnosed diabetics are also often spotted because they pee themselves in public or spend 2/3 of their day pissing away the gallons of water they're chugging. (endofshiftreport.com)
  • However, in a more established disease condition, mere control of the blood glucose levels does not suffice and requires a treatment comprising the inhibition of several other enzymes that are involved in the development of complications. (jabonline.in)