Michelson AM, Blake CC, Evans ST, Orkin SH: Structure of the human phosphoglycerate kinase gene and the intron-mediated evolution and dispersal of the nucleotide-binding domain. (drugbank.com)
They introduced into these cells a lentiviral vector encoding the enzyme α-L-iduronidase (IDUA), which is lacking in Hurler syndrome patients, under the control of the human phosphoglycerate kinase 1 gene promoter. (institut-servier.com)
PHYSIOLOGICAL MODELING [26] H. If patients develop symptoms of rhabdomyolysis after some duration TABLE 99-3 -- ENZYME DEFECTS IDENTIFIED AS A CAUSE OF MYOGLOBINURIA Carnitine palmitoyltransferase Myophosphorylase Phosphofructokinase Phosphorylase kinase Phosphoglycerate kinasePhosphoglycerate mutase Lactate dehydrogenase Myoadenylate deaminase 524 Figure 99-2 ATP is the major energy for muscle. (binary-options-guide.com)
GLYCERALDEHYDE 3-PHOSPHATE D2
MSCs significantly reversed the imbalance of glycolysis in sperm and testis induced by testicular torsion-detorsion, as evidenced by increasing the expression of phosphoglycerate kinase 2 and glyceraldehyde-3-phosphate dehydrogenase-spermatogenic, activating Akt, and increasing glycogen synthase kinase 3 (GSK3), which led to the increase in glycolysis cascades and ATP production. (biomedcentral.com)
Identification, sequence analysis, and expression of a Corynebacterium glutamicum gene cluster encoding the three glycolytic enzymes glyceraldehyde-3-phosphate dehydrogenase, 3-phosphoglycerate kinase, and triosephosphate isomerase. (microbiologyresearch.org)
Enolase2
2-phosphoglycerate is converted to Phosphoenol Pyruvate by removal of one molecule of Water by the action of the enzyme Enolase. (dp.ua)
Although the triose-phosphate isomerase (Tpi), GapA, BAY 11-7082 in vitro phosphoglycerate kinase (Pgk), and enolase (Eno) are all encoded from the gap operon [20], our proteome data showed a significantly lower expression MI-503 in vivo only for GapA, Pgk and Eno. (mek-inhibitors.com)
PGK11
d ) Validation of the yeast mRNA interactome using western blotting of input samples and eluate after interactome capture with specific antibodies (ADH1, alcohol dehydrogenase 1, PUB1) or against TAP-tagged proteins (PGK1, phosphoglycerate kinase 1, TDH1, triose phosphate dehydrogenase, TRX2, thioredoxine 2, SHE2, Swi5p-dependent HO Expression 2). (nature.com)
Glycolysis1
Pyruvate kinase regulation is important for controlling the flux of metabolites, such as fructose (in liver), which enter glycolysis after the PFK step. (flashcardmachine.com)
In complete reverse of the glycolytic pathway reaction, the enzyme phosphoglycerate kinase catalyses the reduction of the carboxyl group of 1,3BPG to form an aldehyde instead. (wikipedia.org)
In this reaction cycle 1,3BPG originates from 3-phosphoglycerate and is made into glyceraldehyde 3-phosphate by the action of specific enzymes. (wikipedia.org)
Use of cultured lymphoblastoid cells for the study of abnormal enzymes: molecular abnormality of a phosphoglycerate kinase variant associated with hemolytic anemia. (univ-amu.fr)
Congratulations - you have completed ENZYMES- Part 12 . (medquizzes.net)
A chemical or drug that inhibits the mitogen-activated protein kinase kinase enzymes MEK1 and/or MEK2. (mek-inhibitors.com)
A single amino acid substitution (Asp leads to Asn) in a phosphoglycerate kinase variant (PGK Munchen) associated with enzyme deficiency. (univ-amu.fr)
1,3-bisphosphoglycerate + ADP ⇌ 3-phosphoglycerate + ATP The transfer of an inorganic phosphate from the carboxyl group on 1,3BPG to ADP to form ATP is reversible due to a low ΔG. (wikipedia.org)
Step 7: Phosphoglycerate Kinase Phosphoglycerate kinase moves a phosphate group from 1,3-bisphosphoglycerate to ADP, creating ATP and 3-phosphoglycerate. (traverse.link)
Mutations1
Identification of new mutations in two phosphoglycerate kinase (PGK) variants expressing different clinical syndromes: PGK Creteil and PGK Amiens. (univ-amu.fr)
We have previously shown that C. pneumoniae contains three Ser/Thr protein kinases and that one of these, PknD, is a membrane-associated Semaxanib supplier kinase that phosphorylates CdsD, a structural protein of the type III secretion system [45]. (mek-inhibitors.com)
Gene2
Singer-Sam J, Keith DH, Tani K, Simmer RL, Shively L, Lindsay S, Yoshida A, Riggs AD: Sequence of the promoter region of the gene for human X-linked 3-phosphoglycerate kinase. (drugbank.com)
Sequence of the promoter region of the gene for human X-linked 3-phosphoglycerate kinase]. (univ-amu.fr)
Reversible1
This is a rare example of a reversible kinase reaction. (dp.ua)
Molecular3
Molecular abnormality of phosphoglycerate kinase-Uppsala associated with chronic nonspherocytic hemolytic anemia. (univ-amu.fr)
Molecular basis for the lack of enantioselectivity of human 3-phosphoglycerate kinase. (univ-amu.fr)
Pathway2
The complete pathway was elucidated in the year 1940. (dp.ua)
For diverse bacteria and archaea that can utilize a carbon source, there is a complete high-confidence catabolic pathway (including a transporter) just 38% of the time, and there is a complete medium-confidence pathway 63% of the time. (lbl.gov)
METHODS: We engaged practitioners from 9 Ohio sites to identify newly diagnosed ALS patients and to complete case report forms with demographic and clinical information. (cdc.gov)
Characterization1
Complete sequencing and characterization of 21,243 full-length human cDNAs. (univ-amu.fr)
Theoretical1
Theoretical and computational advances result in a complete model of energy flow, which predicts that chemical selectivity is possible even in the presence of vibrational relaxation. (illinois.edu)
Step1
Nevertheless, they congratulate the researchers "for moving the field one step closer to an idealized therapy that will someday result in complete correction of Hurler syndrome with minimal toxic effects. (institut-servier.com)
Severe2
Different potato cultivars differ in resistance to PVY, from severe susceptibility, through tolerance, to complete resistance. (biomedcentral.com)
However, in a cord twisting higher than 360° plus symptom duration more than 24 h, complete or severe testicular atrophy is inevitable due to cell necrosis starting from 4 h after testicular torsion. (biomedcentral.com)
Full-length1
Michelson AM, Markham AF, Orkin SH: Isolation and DNA sequence of a full-length cDNA clone for human X chromosome-encoded phosphoglycerate kinase. (drugbank.com)
List2
To find the complete list of publications please use the link above (MPG.PuRe). (mpg.de)
If a value is a list, it specifies the complete list of sidebar templates to include. (myselfie.co.za)