• The genus contains the species Corynebacterium diphtheriae and the nondiphtherial corynebacteria, collectively referred to as diphtheroids. (medscape.com)
  • In some endemic locations, such as India, 44% of throat and nasal swabs tested positive for C diphtheriae and Corynebacterium pseudodiphtheriticum . (medscape.com)
  • Three species ( Corynebacterium diphtheriae , C. ulcerans , and C. pseudotuberculosis ) can potentially produce diphtheria toxin. (cdc.gov)
  • C . diphtheriae is the most common of potentially toxigenic species and is associated with epidemic diphtheria and person-to-person spread. (cdc.gov)
  • Corynebacterium pseudotuberculosis is a facultative intracellular pathogen that belongs to the so-called CMN ( Corynebacterium-Mycobacterium-Nocardia ) group, a distinct subgroup of the Actinobacteria that also includes other highly important bacterial pathogens, such as Corynebacterium diphtheriae and Mycobacterium tuberculosis . (biomedcentral.com)
  • Corynebacterium diphtheriae , the cause of diphtheria in humans. (wikidoc.org)
  • Respiratory diphtheria is a serious infection caused by toxigenic Corynebacterium diphtheriae, and disease transmission mainly occurs through respiratory droplets. (cdc.gov)
  • Here we utilized whole-genome sequencing (WGS) to characterize recovered isolates of C. diphtheriae and two co-circulating non-diphtheritic Corynebacterium (NDC) species - C. pseudodiphtheriticum and C. propinquum. (cdc.gov)
  • Corynebacterium diphtheriae is responsible for both endemic and epidemic diphtheria. (who.int)
  • Corynebacterium diphtheriae est responsable à la fois de la diphtérie endémique et épidémique. (who.int)
  • Case series from Canada, consistent with global surveillance, have found that the disease burden is increasingly attributed to cutaneous, non-pseudomembranous respiratory and systemic disease from toxigenic and non-toxigenic strains of Corynebacterium diphtheriae and C. ulcerans Footnote 2 Footnote 3 Footnote 4 Footnote 5 Footnote 6 Footnote 7 Footnote 8 . (canada.ca)
  • In addition to disease burden, other toxigenic Corynebacteria ( C. ulcerans or C. pseudotuberculosis ) and non-toxigenic C. diphtheriae may serve to maintain a reservoir for toxigenic respiratory diphtheria Footnote 2 Footnote 4 Footnote 8 . (canada.ca)
  • Ruminants-such as sheep, goats, and cattle-can also become infected with these bacteria, although cross-species transmission is rare and usually only occurs between horses and cattle because they can carry the same strain. (eliteequineks.com)
  • Know your common fly species, the diseases they transmit, and ways to deter them from your property. (equishopper.com)
  • Some nondiphtheria species of Corynebacterium produce disease in specific animal species, and some of these are also human pathogens . (wikidoc.org)
  • Some species of Corynebacterium have sequenced genomes that range in size from 2.5 - 3 Mbp. (wikidoc.org)
  • Species of Corynebacterium have been used in the mass production of various amino acids including L-Glutamic Acid , a popular food additive that is made at a rate of 1.5 million tons/ year by Corynebacterium. (wikidoc.org)
  • Of 18 known species, Yersinia (Y.) enterocolitica and Y. pseudotuberculosis cause disease in humans. (hygiene-in-practice.de)
  • The species Y. pseudotuberculosis generally occurs only in 0.5 to 1 percent of cases worldwide. (hygiene-in-practice.de)
  • Both Y. enterocolitica and Y. pseudotuberculosis are zoonoses (diseases that can be transmitted from animals to humans and vice versa), where the main reservoir is found in animal species such as pigs and cattle, but also goats or dogs. (hygiene-in-practice.de)
  • The phages exhibited relatively wide host ranges among Yersinia pseudotuberculosis and related species. (mdpi.com)
  • Nondiphtherial corynebacteria also cause chronic and subclinical diseases in domestic animals and can lead to significant economic losses for farmers. (medscape.com)
  • Clinical diphtheria is caused by toxin-producing corynebacteria. (cdc.gov)
  • Pigeon Fever is the common term for an infection caused by the bacterial organism Corynebacterium pseudotuberculosis (also referred to as Dryland Distemper). (eliteequineks.com)
  • Corynebacterium pseudotuberculosis has been cultured from some cases (particularly of ulcerative lymphangitis, but in others, a bacterial culture is negative. (wikipedia.org)
  • Botulism is an acute severe neuroparalytic disease caused by bacterial exotoxins produced by distinct strains of Clostridium , mainly Clostridium botulinum . (biomedcentral.com)
  • In fact, one might expect that the majority of the virulence determinants of C. pseudotuberculosis would be present in the exoproteome, i.e . the entire set of bacterial proteins found in the extracellular milieu [ 7 ]. (biomedcentral.com)
  • Once found mainly in California, this bacterial infection has now been documented in 25 states across the country. (equusmagazine.com)
  • Among animals with bacterial isolation, Staphylococcus aureus (6/34 = 17.6%), Escherichia coli (5/34 = 14.7%), Staphylococcus beta-hemolytic (5/34 = 14.7%), and Trueperella pyogenes (3/34 = 8.8%) were predominant, in addition to a miscellaneous of other bacteria isolated in minor frequency, e.g. (bvsalud.org)
  • causes bacterial meningitis, fulminating septicaemia, pulmonary and ophthalmic infections, chronic synovitis (joint pain/inflammation), skin diseases, wound infections and postoperative urinary tract infections. (microgeninc.com)
  • causes a bacterial upper respiratory disease in pigs, resulting in lethargy, cough, and other breathing difficulties. (microgeninc.com)
  • causes severe bacterial mastitis in cattle, characterized by thick, purulent (pussy) secretion. (microgeninc.com)
  • These pathogens are the third most common cause of bacterial intestinal diseases in Germany after salmonella and campylobacter. (hygiene-in-practice.de)
  • Hot, dry weather is the most common environment where the organism is found, and most pigeon fever cases appear in late summer/early fall (the author first diagnosed a case in August, and her number of cases has increased exponentially since that time). (eliteequineks.com)
  • c) The organism is not a bacterium, but a fungus , so is very difficult to culture. (wikipedia.org)
  • [3] However, intracellular organisms such as Corynebacterium pseudotuberculosis will be susceptible to certain antibiotics in vitro that are not effective for the specific organism in the horse. (wikipedia.org)
  • The organism is transmitted via airborne route and can cause respiratory obstruction and heart failure because of the exotoxin it produces. (who.int)
  • In some cases, however, it is pathogenic and causes infection, including yeast infections that are contracted by many women. (umaine.edu)
  • This article provides an overview of the most important human pathogenic bacteria. (amboss.com)
  • The following table provides an overview of the nomenclature of important human pathogenic bacteria, according to their form and Gram staining properties. (amboss.com)
  • 44 proteins were commonly identified in two different strains, isolated from distinct hosts, then composing a core C. pseudotuberculosis exoproteome. (biomedcentral.com)
  • Comparative analyses of the exoproteomes of two C. pseudotuberculosis strains, in addition to comparison with other experimentally determined corynebacterial exoproteomes, were helpful to gain novel insights into the contribution of the exported proteins in the virulence of this bacterium. (biomedcentral.com)
  • Also, multidrug resistance to ≥ 3 classes of antimicrobials was found in 23.5% (8/34) strains. (bvsalud.org)
  • In Europe, the Y. enterocolitica strains of the so-called bioserovar 4/O:3 are the most frequent cause of yersiniosis (more than 90 per cent), the bioserovar 1B/O:8 has so far been geographically limited to North America, and in Europe is associated with travel. (hygiene-in-practice.de)
  • In western Europe, toxigenic Corynebacterium ulcerans has increasingly been identified as the etiologic agent. (cdc.gov)
  • Currently, no direct evidence has been found of person-to-person spread of C . ulcerans or C . pseudotuberculosis . (cdc.gov)
  • Once a horse becomes infected with C. pseudotuberculosis, the bacteria release a toxin that ultimately spurs the body to build a thick-walled abscess around the pathogens. (equusmagazine.com)
  • When identified as the predominant isolate in sputum from a patient with CAP, Corynebacterium spp. (biomedcentral.com)
  • The present study examined the possibilities that: (i) careful examination of Gram-stained sputum and culture plates may reveal a predominant bacterium such as Corynebacterium spp. (biomedcentral.com)
  • While infection can occur by the fecal-oral route, ingestion of bacteria in raw or undercooked seafood, usually oysters, is the predominant cause the acute gastroenteritis caused by V. parahaemolyticus. (datapunk.net)
  • The biotype of Corynebacterium pseudotuberculosis affecting horses and cattle is distinguishable from the biotype that infects small ruminants based on its ability to reduce nitrate in vitro. (wikipedia.org)
  • C . pseudotuberculosis rarely infects humans and is typically associated with farm animals ( 7 ). (cdc.gov)
  • causes bronchitis in humans and can cause kennel cough in dogs. (microgeninc.com)
  • Common prion diseases include Creutzfeldt-Jakob disease (CJD) in humans, bovine spongiform encephalopathy (BSE or mad cow disease) in cattle, scrapie in sheep and goats and chronic wasting disease (CWD) in cervids (mule deer, white-tailed deer, American elk, moose, and reindeer). (infectiousconferences.com)
  • Huge efforts have been undertaken in many laboratories around the world to understand the public health risks posed by prions from animals ever since BSE was found in 1990's to cause variant CJD (vCJD) in humans. (infectiousconferences.com)
  • Vibrio parahaemolyticus is a curved, rod-shaped, Gram-negative bacterium found in brackish saltwater, which, when ingested, causes gastrointestinal illness in humans. (datapunk.net)
  • [ 5 ] Today, the more common scenario is nondiphtherial corynebacterial bacteremia associated with device infections (venous access catheters, heart valves, neurosurgical shunts, peritoneal catheters), as well as meningitis , septic arthritis , and urinary tract infections. (medscape.com)
  • causes opportunistic infections and fever. (microgeninc.com)
  • causes severe respiratory infections in the immunocompromised. (microgeninc.com)
  • This is why, in case of major outbreaks, human and veterinary medicine must work jointly to examine infections and find the origin of contamination as soon as possible. (hygiene-in-practice.de)
  • Wound infections also occur, but are less common than seafood-borne disease. (datapunk.net)
  • certain localized infections Note: Categories for "late effects" of infectious and parasitic diseases are to be found at 137. (cdc.gov)
  • When DNA of the phage integrates into the host bacteria's genetic material, the bacteria develop the capacity to produce this polypeptide toxin. (medscape.com)
  • Consumption of foods contaminated with B. cereus may result in disease either by the consumption of pre-formed toxin or by toxins produced by these bacteria in during growth the gut. (microgeninc.com)
  • Immunotherapy consists of the use of specific antibodies to neutralize the main causes of these afflictions. (biomedcentral.com)
  • Botulism, diphtheria, tetanus and rabies are severe infectious diseases caused by different agents, which have in common the recommendation of using immunotherapy as post-exposure treatment and/or prophylaxis [ 1 , 2 ]. (biomedcentral.com)
  • The goat suffers with various disease, which are caused by bacteria, viruses, parasites and other non- infectious agents. (health-articles.net)
  • Culture of active lesions for Corynebacterium pseudotuberculosis is diagnostically definitive. (msdvetmanual.com)
  • Once established on a farm or region (endemic), it is primarily maintained by contamination of the environment with active draining lesions, animals with the internal form of the disease that contaminate the environment through nasal discharge or coughing, the ability of the bacteria to survive harsh environmental conditions, and lack of strict biosecurity necessary to reduce the number and prevent introduction of new cases. (msdvetmanual.com)
  • Despite the fact that C. pseudotuberculosis is sensitive in vitro to almost all antibiotics that have been tested, antibiotic therapy is not very efficient. (wikipedia.org)
  • These bacteria also have natural resistance to many antibiotics. (microgeninc.com)
  • Well-recognized and common causes of community-acquired pneumonia (CAP) in adults include bacteria such as Streptococcus pneumoniae, Haemophilus influenzae , and Staphylococcus aureus , and viruses such as influenza virus, respiratory syncytial virus, human metapneumovirus, and parainfluenza virus. (biomedcentral.com)
  • Pyomyositis is most often caused by the bacterium Staphylococcus aureus . (mdwiki.org)
  • Corynebacterium is a genus of Gram-positive , facultatively anaerobic , non- motile , rod-shaped actinobacteria . (wikidoc.org)
  • In temperate countries such as the US, pyomyositis was a rare condition (accounting for 1 in 3000 pediatric admissions), but has become more common since the appearance of the USA300 strain of MRSA . (mdwiki.org)
  • Affected horses should be isolated because drainage from their abscesses contains a high amount of bacteria that will contaminate the environment. (eliteequineks.com)
  • The spores of B. cereus bacteria commonly contaminate raw foods and food materials, particularly foods that have been in contact with soil. (microgeninc.com)
  • Gonococcal pyomyositis is a rare infection caused by Neisseria gonorrhoeae . (mdwiki.org)
  • In this work, olive leaf waste was valorized by silver nitrate to produce silver nanoparticles (OLAgNPs), which exhibited various biological, antioxidant, anticancer activities against three cancer cell lines, and antimicrobial activity against multi-drug resistant (MDR) bacteria and fungi. (mdpi.com)
  • Throughout the cortex, there are multiple abscesses containing abundant colonies of bacteria that often involve glomeruli (arrow). (avma.org)
  • The infection can spread through the blood or lymphatic system, causing abscesses to form in other lymph nodes or internal organs throughout the body. (wikipedia.org)
  • Abscesses grow gradually over time, and if they are located close to the skin, rupture is common. (wikipedia.org)
  • C. pseudotuberculosis bacteria tend to localize and form abscesses in the pectoral region and ventral abdomen of the horse. (eliteequineks.com)
  • It was named because the abscesses cause swelling and give the horse's chest a "pigeon-breast" appearance. (eliteequineks.com)
  • Your veterinarian can also ultrasound the abscesses and find the best place to drain them. (eliteequineks.com)
  • If the abscesses are deep and causing pain and discomfort to the horse, Banamine (flunixin meglumine) can be administered. (eliteequineks.com)
  • The infection, which usually causes abscesses in the chest or elsewhere in the horse's body, was first reported in horses in San Mateo County (San Francisco Bay Area) of California in 1915. (equusmagazine.com)
  • Internal abscesses can develop when the bacteria are carried into the body and infect the liver, kidney, lungs or other internal organs. (equusmagazine.com)
  • Abscesses form within lymph channels, causing marked swelling of a leg with abscesses that open along a chain or progress into cellulitis. (equusmagazine.com)
  • causes various abscesses, mostly in the human gut. (microgeninc.com)
  • CT scan can confirm the diagnosis before abscesses occur with enlargement of the involved muscles and hypodensity when abscess is present, terogenous attenuation and fluid collection with rim enhancement can be found. (mdwiki.org)
  • These opportunistic anaerobic bacteria may also cause bed sores, pressure sores, aspiration pneumonia, chronic otitis media (ear infection), chronic sinusitis, and osteomyelitis (bone infection). (microgeninc.com)
  • causes diarrhea in cattle and can cause reproductive problems in pigs. (microgeninc.com)
  • Pigeon fever cases used to be found primarily in California, although within the last several years veterinarians have diagnosed cases in many areas of the western United States. (eliteequineks.com)
  • For much of the 20th century, pigeon fever was most commonly found in the Southwest and in California. (equusmagazine.com)
  • This is by far the most common form of pigeon fever. (equusmagazine.com)
  • The authors of the present study have previously hypothesized that unrecognized aspiration of less virulent bacteria that normally inhabit the nasopharynx might also cause pneumonia, especially in persons whose upper airways are bypassed or whose ability to clear aspirated organisms is damaged [ 5 ]. (biomedcentral.com)
  • and (iii) these organisms are in fact the cause of some cases of pneumonia. (biomedcentral.com)
  • The common diseases of goat, their symptoms, treatment, and methods used in Sindh-Pakistan. (health-articles.net)
  • The important clinical symptoms of common diseases have been given, only to help the farmers to detect the sick goat at the earliest. (health-articles.net)
  • In small children, yersiniosis caused by Y. enterocolitica results in one to three weeks of gastrointestinal disorder with fever, abdominal pain and bloody diarrhoea. (hygiene-in-practice.de)
  • Flies are a major vector and can spread the bacteria, so spray affected and unaffected horses (especially ones with open wounds) with fly repellent if it is still fly season. (eliteequineks.com)
  • The infection can spread to the horse's legs, causing a syndrome called ulcerative lymphangitis, which can be difficult to treat. (eliteequineks.com)
  • The swellings can, however, appear anywhere on the body, especially if the bacteria entered the horse's body through a cut or abrasions. (equusmagazine.com)
  • represent a noteworthy clinical cause of pneumonia. (biomedcentral.com)
  • This bacterium is of relatively low clinical significance, but is used frequently to test water filters due to its very small size. (microgeninc.com)
  • Clinical symptoms: Abortion in late pregnancy is the feature of the disease, retention of placenta and metritis are common. (health-articles.net)
  • Diphtheria is a now-rare vaccine-preventable disease (VPD) associated with a wide range of clinical illnesses, depending on the infection site and the toxigenicity of the bacteria. (canada.ca)
  • Ulcerative lymphangitis, which causes swelling and ulcerations on the lower legs, accounts for only about 1 percent of all cases. (equusmagazine.com)
  • Each PAI variant contains a genetically-distinct Type III Secretion System (T3SS), which is capable of injecting virulence proteins into host cells to disrupt host cell functions or cause cell death by apoptosis. (datapunk.net)
  • Aside from the T3SS, two genes encoding well-characterized virulence proteins are typically found on the PAI, the thermostable direct hemolysin gene (tdh) and/or the tdh-related hemolysin gene (trh). (datapunk.net)
  • a component of this flora, is commonly viewed as a contaminant, but it may be the cause of pneumonia and the frequency with which it causes CAP may be underestimated. (biomedcentral.com)
  • Gram-positive bacilli that are often dismissed as contaminants have been reported to cause pneumonia (Table 1 ). (biomedcentral.com)
  • BACKGROUND: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the cause of coronavirus disease 2019 (COVID-19), has spread globally and is being surveilled with an international genome sequencing effort. (cdc.gov)
  • Moreover, evidence could be found for probable non-classical export of most of the remaining proteins. (biomedcentral.com)
  • The metabolic pathways of Corynebacterium have been further manipulated to produce L-Lysine and L-Threonine . (wikidoc.org)
  • This metabolic imbalance caused due to goat fed large quantities of concentrated food. (health-articles.net)
  • Recent outbreaks in frozen foods contaminated with Listeria monocytogenes have caused a desire to increase sanitizing capacity of post-harvest processing lines. (umaine.edu)
  • In the cases of botulism, diphtheria and tetanus, the main objective of immunotherapy is to neutralize toxins, but also to opsonize the bacteria, promoting complement-dependent bacteriolysis. (biomedcentral.com)
  • Often referred to as fat- or big-leg disease, it is sometimes known as weed or Monday-morning disease (not to be confused with the more common usage of MMD referring to exertional rhabdomyolysis or azoturia ). (wikipedia.org)
  • d) The disease has another cause. (wikipedia.org)
  • This form of the disease isn't common-accounting for only 8 percent of all cases, according to Spier's study. (equusmagazine.com)
  • Most do not cause disease, but are part of normal human skin flora . (wikidoc.org)
  • Treatment is not complete and many drugs may cause toxicity, in cases of the serious disease problem of the goat. (health-articles.net)