• Resectoscopic treatment can be considered effective in small size defects, but no randomized clinical trials are available. (europeanreview.org)
  • Secondary outcomes will include change in clinical diagnosis following genomic testing, change in clinical management following genomic testing and the cost-effectiveness of genomic testing compared with usual care. (bmj.com)
  • Background Therapeutic hypothermia improves outcomes for asphyxiated infants, however not all infants born with severe acidosis are assessed as eligible for cooling and few data describe short-term clinical outcomes for the whole cohort of babies with severe perinatal acidosis. (bmj.com)
  • Conclusions: The CIRT is the largest observational study on radioembolization to date and will provide valuable insights to the clinical application of this treatment modality and its real-life outcomes. (unav.edu)
  • AHRQ invites applications to develop a prospective clinical registry of orthopedic devices, drugs, and procedures through a practice-based research collaborative and clinical and outcomes data resource (P50 grant mechanism). (nih.gov)
  • The data collection efforts funded by this FOA should be ideally designed in a way to take advantage of and advance in scientific, technical, and operational terms existing local clinical and patient outcomes data collection effort and/or registries. (nih.gov)
  • The newly developed registry will also provide the infrastructure to conduct multi-center collaborative clinical studies to address effectiveness and patient outcomes questions as well as emerging public health issues related to orthopedic procedures and devices. (nih.gov)
  • To our knowledge, this is the first prospective controlled trial demonstrating better outcomes of resectoscopic treatment of isthmocele in solving symptoms compared with expectant management. (europeanreview.org)
  • The distinguishing feature of a prospective cohort study is that at the time that the investigators begin enrolling subjects and collecting baseline exposure information, none of the subjects have developed any of the outcomes of interest. (wikipedia.org)
  • After baseline information is collected, subjects in a prospective cohort study are then followed "longitudinally," i.e. over a period of time, usually for years, to determine if and when they become diseased and whether their exposure status changes outcomes. (wikipedia.org)
  • Here we report the secondary outcomes of intervention efficacy on clinical symptoms, as assessed by Scoring Atopic Dermatitis (SCORAD) and Patient-Oriented Eczema Measure (POEM), on health-related quality of life (HR QoL) as assessed by Dermatology Life Quality Index (DLQI), and changes in behaviors related to disease management as assessed by a six-item questionnaire. (humaninsight.it)
  • CONCLUSION: Patients with AD are open to and can benefit from a digitally delivered targeted intervention, as demonstrated by significant improvements in treatment adherence and related clinical outcomes. (humaninsight.it)
  • The clinical validity of a test refers to its accuracy in identifying a patient's clinical status, whereas clinical utility refers to its ability to improve health outcomes, taking both potential benefits and risks into account. (cdc.gov)
  • Based on a preceding validation study of sCT, this study aims to investigate MRI-only brain RT through a prospective clinical feasibility study with endpoints for dosimetry and patient setup. (lu.se)
  • This is a prospective controlled study to assess feasibility and efficacy of surgical hysteroscopic treatment of cesarean-induced isthmocele on symptom relief. (europeanreview.org)
  • The aim of this study is to investigate the feasibility of sentinel node biopsy in patients currently not regarded suitable for the technique. (ki.se)
  • METHODS: Adults with mild-to-severe AD were recruited for a 6-week feasibility study. (humaninsight.it)
  • METHODS: The authors conducted a prospective feasibility study of consecutive patients with rhegmatogenous retinal detachment treated with scleral buckling surgery and postoperative laser during an 18-month period with a minimal follow-up of 6 months. (eyehospital.nl)
  • abstract = "PURPOSE: To evaluate postoperative laser photocoagulation as retinopexy mode in patients with rhegmatogenous retinal detachment treated with scleral buckling surgery.METHODS: The authors conducted a prospective feasibility study of consecutive patients with rhegmatogenous retinal detachment treated with scleral buckling surgery and postoperative laser during an 18-month period with a minimal follow-up of 6 months. (eyehospital.nl)
  • The Strengthening the Reporting of OBservational studies in Epidemiology (STROBE) recommends that authors refrain from calling a study 'prospective' or 'retrospective' due to these terms having contradictory and overlapping definitions. (wikipedia.org)
  • Design Prospective multicentre data of SSA/Ps ≥20 mm referred for treatment by endoscopic mucosal resection (September 2008-July 2013) were analysed. (bmj.com)
  • The current prospective multicentre trial investigated the sensitivity of preoperative mediastinal staging by video-assisted mediastinoscopy (VAM) or VAM-lymphadenectomy (VAMLA). (istanbul.edu.tr)
  • Patients were enrolled in the study during a 5-year period in a private periodontal practice. (nih.gov)
  • On a scale of 1 to 10, rate how much this article will change your clinical practice? (orthobullets.com)
  • Objective: The main objective is to collect data on the clinical application of radioembolization with 90Y resin microspheres to improve the understanding of the impact of this treatment modality in its routine practice setting. (unav.edu)
  • The registry will be a model and basis for other national device and procedure registries and will actively disseminate study results into clinical practice. (nih.gov)
  • Nephron Clinical Practice. (wikipedia.org)
  • Polygenic Risk Scores in Clinical Practice? (cdc.gov)
  • However, to date there has not been strong evidentiary support for their routine use in clinical and public health practice. (cdc.gov)
  • Building the evidence base for use of PRS in clinical practice requires evaluation of their performance characteristics. (cdc.gov)
  • Prospective QA was performed prior to MRI-only treatment approval, comparing sCT and CT image characteristics and calculated dose distributions. (lu.se)
  • In this study, we investigated the different characteristics of the first 150 COVID-19 patients in Lebanon, including the diagnostic criteria, outcome, demographics, and clinical, radiological and biological characteristics. (who.int)
  • To assess the clinical characteristics of hospitalized COVID-19 infected children below 14 years of age and to describe atypical presentations of COVID-19 in children. (pediatriconcall.com)
  • We sought to describe the incidence and clinical characteristics of malignancies in patients with IgG4-RD. Based on these results, significant factors were evaluated to determine whether they were related to malignancy. (nature.com)
  • Outline the evolving epidemiological risk factors and clinical characteristics of melioidosis and when to consider melioidosis as a potential diagnosis. (cdc.gov)
  • Certainly, daily measurements of lipase are of no value in the assessment of the patient's clinical progress or ultimate prognosis. (medscape.com)
  • Results: Between January 2015 and December 2017, 1047 patients were included in the study. (unav.edu)
  • A study reports high levels of CRP associated with clinical prognosis in the time window between 12 and 72 hours after ischemic stroke [ 17 , 18 ]. (hindawi.com)
  • No markers are available in clinical settings to predict therapy failure and prognosis for patients after primary therapy for cervical cancer. (ki.se)
  • This prospective cohort study aims to investigate the incidence, related factors and prognosis of IgG4-related disease (IgG4-RD) with malignancies in the Chinese cohort. (nature.com)
  • Data regarding demographics, clinical features, treatment and prognosis of IgG4-RD patients complicating malignancies were collected and compared to those of age- and sex-matched controls. (nature.com)
  • The authors ask whether disparate results of recent consensus conferences, which ``good old'' clinical markers, if optimally analysed, might have attempted, using simple criteria, to define ``low- have a similar discriminating power with regard to breast risk'' patients for whom adjuvant chemotherapy should cancer prognosis as the microarray gene expression pro- not be recommended. (lu.se)
  • Aims: To study the clinical, radiological and virological features of the first 150 patients with COVID-19 in Lebanon. (who.int)
  • Our study shows that pediatrics patients with COVID-19 have a simple transmission mode, either by close contact with infected adults or by exposure to epidemic areas. (pediatriconcall.com)
  • Clinical features of confirmed COVID-19 cases cover a wide spectrum. (who.int)
  • All the children with RT-PCR confirmed COVID-19 (Nasopharyngeal or oropharyngeal swabs) or a positive SARS-CoV-2 antibody test between 14th April to 30th October 2020 were enrolled in this study. (pediatriconcall.com)
  • Prospective cohort studies are typically ranked higher in the hierarchy of evidence than retrospective cohort studies and can be more expensive than a case-control study. (wikipedia.org)
  • One of the advantages of prospective cohort studies is they can help determine risk factors for being infected with a new disease because they are a longitudinal observation over time, and the collection of results is at regular time intervals, so recall error is minimized. (wikipedia.org)
  • This is a nationwide, prospective, longitudinal study investigating general and vulvar cancer specific quality of life, treatment-related morbidity, levels of anxiety and depression, unmet needs, satisfaction with care and further aspects of sexual and socio-psychological well-being using a validated questinnaire. (ki.se)
  • Canadian Longitudinal Study on Aging / Étude longitudinale canadienne sur le vieillissement (CLSA-ÉLCV) The CARTaGENE cohort / Quebec's largest prospective study , Quebec, Canada Cebu Longitudinal Health and Nutrition Survey, the Philippines Framingham Heart Study, USA. (wikipedia.org)
  • The present study highlights the efficacy and safety of a combination of B. clausii 088AE, B. coagulans LBSC and B. subtilis PLSSC and demonstrates their immunomodulatory effect in acute allergic rhinitis. (mendeley.com)
  • The aim of another study was to assess the efficacy of homeopathic remedies for the prevention and treatment of migraine in children [28] . (researchgate.net)
  • The results of this study showed the efficacy of homeopathic preparations for the prevention and treatment of migraine attacks in children [28] . (researchgate.net)
  • We aimed to test the clinical efficacy of a digital program in patients with AD. (humaninsight.it)
  • Tailored interventions are needed to identify and manage sleep disorders, particularly as most of the sleep disorders detected in the Raine Study had not previously been diagnosed. (mja.com.au)
  • Interventions: Interventions included serial clinical, biochemical, and ultrasonographic assessments before and throughout pregnancy. (unimore.it)
  • Monthly quantities of all antimicrobial drugs delivered analysis is considered the strongest quasi-experimental to each hospital ward during the study period were export- method to ascertain the longitudinal effect of healthcare ed from the pharmacy information system and stored both interventions (13-15). (cdc.gov)
  • CRP is of clinical importance as an early prognostic factor after stroke because it is an easily measured and clinically common indicator of inflammation. (hindawi.com)
  • Hence, we evaluated procalcitonin (PCT) as a prognostic marker in this study.Objectives: We aimed to study the role of PCT, CRP, and ESR levels in predicting clinical outcome of acute DFI.Materials and Methods:A total of 250 subjects (197 men, 53 women) with acute DFI were enrolled. (amrita.edu)
  • Clinical features and prognostic factors of listeriosis: the MONALISA national prospective cohort study. (cdc.gov)
  • As adjuvant therapies have cular biology of breast cancer, clinical decision-making costs and side-effects associated with them, various still largely relies on pathological staging, grading and prognostic criteria have been established to guide the steroid receptor status. (lu.se)
  • Our research is primarily focused on clinical trials, cancer epidemiology and translational research in gynecological malignancies. (ki.se)
  • The present study focused on the association between IgG4-RD and malignancies. (nature.com)
  • Polypharmacy and health related quality of life among older adults on antiretroviral therapy in a tertiary hospital in Tanzania: a hospital-based cross-sectional study. (harvard.edu)
  • Predictors of mortality among adolescents and young adults living with HIV on antiretroviral therapy in Dar es Salaam, Tanzania: a retrospective cohort study. (harvard.edu)
  • Effect of aspirin on HIV disease progression among HIV-infected individuals initiating antiretroviral therapy: study protocol for a randomised controlled trial. (harvard.edu)
  • Several weaknesses have been identified in previous studies and in 2019, we initiated the RACC-trial (Robot-assisted Approach to Cervical Cancer). (ki.se)
  • This study assessed fibromyalgia patients at 2 time points, 2 years apart, to evaluate changes in symptoms, quality of life, medication use, and healthcare resource use. (medpagetoday.com)
  • Objectives: The study objective was to evaluate the effectiveness of homeopathic medicines for the prevention and treatment of migraine in children. (researchgate.net)
  • Randomised clinical trials have shown an overall duction of techniques that can simultaneously evaluate benefit for both adjuvant chemotherapy and endocrine the expression of large numbers of tumour genes. (lu.se)
  • In a prospective clinical study including 114 patients with acute necrotizing pancreatitis, but excluding patients with a pancreatic abscess, necrotic material obtained at surgery was tested bacteriologically. (nih.gov)
  • Present study was aimed to study, acute fissure-in-ano in relation to clinical diagnosis and management at a tertiary hospital. (researchbib.com)
  • Present study was hospital based prospective observational study, conducted in patients between 18-70 years of age ( including males & females ), with symptoms of pain on defecation, bright red bleeding, constipation (i.e. suspected cases of acute anal-fissure). (researchbib.com)
  • Bacteriostatic, immune modulating, anti-inflammatory and analgetic effects of homeopathic mono-preparations Aconitum D4, Phytolacca D1, Bryonia D and D4, Lachesis D8, Mercurius solubilis D4 were investigated in a study on fifty cows with acute mastitis. (researchgate.net)
  • A prospective clinical study of Epstein-Barr virus and host interactions during acute infectious mononucleosis. (cdc.gov)
  • It may also be reasonable, depending on the clinical presentation, to check for indicators of inflammation, assess thyroid function, and perform a basic metabolic panel to rule out a concomitant medical illness. (medscape.com)
  • Only 35% of the reactivation infections were associated with clinical symptoms. (bmj.com)
  • In this prospective, randomized, multi-center double-blind multicenter trial, we now determine if intraperitoneal local anesthetics administered perioperatively during 72 h leads to early start of chemotherapy compared to placebo in patients undergoing cytoreductive surgery for FIGO stage III-IV ovarian cancer ( https://clinicaltrials.gov/ct2/show/NCT04065009 ). (ki.se)
  • It is a prospective national multicenter trial with participation of all four Swedish hospitals accredited for treating vulvar cancer patients. (ki.se)
  • The diagnosis of myofascial pain is clinical, with no confirmatory laboratory tests available. (medscape.com)
  • As previously stated, the diagnosis of myofascial pain is clinical, with no confirmatory laboratory tests available. (medscape.com)
  • In addition, imaging studies often reveal nonspecific change only and typically are not helpful in making the diagnosis of cervical myofascial pain. (medscape.com)
  • Several research articles have attempted to identify changes on electromyograms/nerve conduction velocity studies that may be unique to patients with myofascial pain. (medscape.com)
  • The aim of this study is to explore the clinical utility and cost-effectiveness of genomic testing within a national cohort of patients with suspected genetic kidney disease who attend multidisciplinary renal genetics clinics. (bmj.com)
  • A prospective study of cytomegalovirus and herpes simplex virus disease in renal transplant recipients. (bmj.com)
  • A prospective study of 84 renal graft recipients demonstrated cytomegalovirus (CMV) disease after transplantation in 37% of patients. (bmj.com)
  • Botulinum toxin A in the treatment of chronic tension-type headache With cervical myofascial trigger points: a randomized, double-blind, placebo-controlled pilot study. (medscape.com)
  • A virologic pilot study of valacyclovir for infectious mononucleosis. (cdc.gov)
  • On July 27th of this year, CDC released a health advisory through the Health Alert Network, alerting clinicians and public health officials throughout the country to consider melioidosis in patients whose clinical presentation is compatible with signs and symptoms of the disease, regardless of travel history to international disease endemic regions. (cdc.gov)
  • Thirty days after cement removal, 25 of 33 test sites from which the cement was removed had no clinical or endoscopic signs of inflammation. (nih.gov)
  • Clinical and endoscopic signs of peri-implant disease were absent in 74% of the test implants after the removal of excess cement. (nih.gov)
  • We aimed to describe the clinical and endoscopic predictors of SSA/P-D and high grade dysplasia (HGD) or cancer. (bmj.com)
  • Histological findings were correlated with clinical and endoscopic findings. (bmj.com)
  • Results: Pregnant women with PCOS had higher WBC, CRP, and ferritin levels at study entry and at all gestational ages than controls. (unimore.it)
  • This report is based on 87 children brought to the casualily department of Al-Jalla Hospital, a teaching unit of the faculty of medicine in Benghazi, with one or other complications following circumcision during the period of study. (lml.com.ly)
  • Objective: The objective of the study was to test the hypothesis that the low-grade chronic inflammation state typical of PCOS patients persists during gestation and is exacerbated by pregnancy and contributes to the increased risk of obstetric/neonatal complications. (unimore.it)
  • Despite the recent availability of validated synthetic CT (sCT) methods for the head region, there are no clinical implementations reported for brain tumors. (lu.se)
  • Methods and analysis This is a prospective observational cohort study performed at 16 centres throughout Australia. (bmj.com)
  • Our study underlines the variable presentation of COVID-19, the difference in severity, and the diverse methods of diagnosis. (who.int)
  • Prospective study of women using different methods of contraception. (ox.ac.uk)
  • Procoagulant alterations and thrombocytopenia in falciparum malaria correlate with parasitemia, serum levels of tumor necrosis factor α (TNFα), and clinical severity. (ajtmh.org)
  • In central India, little is known about the clinical spectrum and severity of COVID-19 in children. (pediatriconcall.com)
  • Morphologic and clinical alterations were more severe, and the mortality rate was significantly elevated, in patients with a short history of disease and bacterial contamination of necrotic tissue. (nih.gov)
  • The predictive potential of the diathesis was tested by determining whether clinical correlates of past suicidal behavior predict suicidal acts during a 2-year follow-up of patients with a major depressive episode. (unboundmedicine.com)
  • Longstanding groin pain is a difficult diagnostic challenge for sports physicians, and the lack of consensus on diagnostic criteria and taxonomy makes comparison of published studies difficult. (bmj.com)
  • Clinical assessment, diagnostic investigations and follow-up. (bmj.com)
  • Diagnostic hysteroscopy was performed as an office procedure in all 47 patients included in the study to confirm and identify the size of the defect. (europeanreview.org)
  • Part two of the call will focus on clinical presentation of melioidosis, followed by diagnostic considerations, treatment, prevention, and key messages. (cdc.gov)
  • The effect of B. clausii, B. coagulans and B. subtilis is well established for immunomodulatory activity in human studies and proven to be safe (Gupta and Maity, 2021). (mendeley.com)
  • To help achieve the objectives of the EHC program, AHRQ will provide support to develop and maintain the infrastructure of a multi-center orthopedic registry and the conduct of multiple collaborative, prospective multi-center studies of orthopedic devices and procedures. (nih.gov)
  • The study population was 35 elite fencers (14 males and 21 females) proficient in three fencing styles (foil, sabre, épée) who underwent clinical and echographic assessment in March 2007 (baseline) and in April 2010 (follow-up). (minervamedica.it)
  • To study specific personal barriers to ART adherence. (ajol.info)
  • A significant interaction was observed between increased treatment adherence and clinical improvement, such that larger clinical improvements were observed in patients with higher treatment adherence. (humaninsight.it)
  • Residual excess cement after placement of fixed partial dentures has been associated with clinical and radiographic signs of peri-implant disease. (nih.gov)
  • Thirty-nine consecutive patients with implants exhibiting clinical and/or radiographic signs of peri-implant disease were studied. (nih.gov)
  • This study will investigate the effects of oral progesterone for older women and testosterone for older men on QT intervals. (nih.gov)
  • A large-scale pilot distribution study was conducted to investigate the impacts of blending different source waters on distribution water qualities, with an emphasis on metal release (i.e. corrosion). (who.int)
  • Congenital Heart Disease GEnetic NEtwork Study (CHD GENES). (nih.gov)
  • This study will find both common genetic causes of congenital heart disease and ways that genes influence results of medical treatment. (nih.gov)
  • In a recent systematic review of the existing evidence for clinical utility of PRS, 22 of the 591 articles reviewed provided strong evidence of clinical validity, but not a single article demonstrated clinical utility. (cdc.gov)
  • The authors of the systematic review concluded that we are not ready to incorporate PRS into clinical settings. (cdc.gov)
  • Trends in Hospitalisation for Human Immunodeficiency Virus in a Tertiary Hospital in Dar es Salaam, Tanzania: A Case study. (harvard.edu)
  • Various interesting factors including place of circumcision, name of operator, use of anaesthesia and different types of injuries to male external genitalia are studied. (lml.com.ly)
  • A prospective cohort study is a longitudinal cohort study that follows over time a group of similar individuals (cohorts) who differ with respect to certain factors under study, to determine how these factors affect rates of a certain outcome. (wikipedia.org)
  • Clinical outcome was assessed based on mobility and morbidity status of the subject. (amrita.edu)
  • Outcome measures were total retinal reattachment and the occurrence of proliferative vitreoretinopathy (PVR).RESULTS: A total of 123 patients (124 eyes) were included in this study. (eyehospital.nl)
  • To determine the usefulness and validity of the clinical classification proposed by Holmich et al in a primary care sports medicine population. (bmj.com)
  • Many studies have demonstrated clinical validity of PRS for different diseases. (cdc.gov)
  • If we want PRS to make a meaningful difference in population health, studies on clinical validity that demonstrate differences in risk distributions between affected and unaffected groups are only a starting point. (cdc.gov)
  • Pathak S, Lazarus M, Ghanghoriya P. Clinical Spectrum and Atypical Presentations of COVID-19 in Hospitalized Children in a Tertiary Care Hospital: Prospective Observational Study. (pediatriconcall.com)
  • Setting: The study was conducted at the Academic Department of Obstetrics and Gynecology of the 'Pugliese-Ciaccio' Hospital of Catanzaro (Catanzaro, Italy). (unimore.it)
  • Cost-effectiveness studies on use of PRS in population-based settings are needed to provide evidence for clinical utility. (cdc.gov)
  • Efforts to diversify data in genomic research are on the rise now but studies on the clinical utility of PRS in low to middle income countries are needed. (cdc.gov)
  • The prospective study is important for research on the etiology of diseases and disorders. (wikipedia.org)
  • Potential predictors of suicidal acts in the 2 years after study enrollment were identified on the basis of an association with previous suicidal behavior and were tested by using Cox proportional hazards regression analysis. (unboundmedicine.com)
  • The purpose of this study was to explore the relationship between excess dental cement and peri-implant disease using the dental endoscope. (nih.gov)
  • None of the controls and all 42 of the test implants had clinical signs of peri-implant disease at initial treatment. (nih.gov)
  • Interstitial lung disease and neuropathy as predominant extra-articular manifestations in patients with rheumatoid arthritis: a prospective study. (medscimonit.com)
  • Caerphilly Heart Disease Study, UK. (wikipedia.org)
  • A quarter of patients with clinical N1 (cN1) non-small cell lung cancer (NSCLC) based on positron emission tomography-computed tomography (PET-CT) imaging have occult mediastinal nodal involvement (N2 disease). (istanbul.edu.tr)
  • In a prospective study, endosonography alone had an unsatisfactory sensitivity (38%) in detecting N2 disease. (istanbul.edu.tr)
  • To participate in this study, you or your child must have congenital heart disease. (nih.gov)
  • To participate in this study, you must be an adult with congenital heart disease with or without a family member with congenital heart disease. (nih.gov)
  • This study aims to bridge the gap in knowledge between known executive function deficits in childhood congenital heart disease and adult well-being. (nih.gov)
  • Currently employed 22‐year‐old Raine Study participants who underwent in‐laboratory sleep disorder screening for moderate to severe obstructive sleep apnoea (apnoea-hypopnea index of more than fifteen events/hour or obstructive sleep apnoea syndrome) and were assessed for insomnia and restless legs syndrome using validated measures. (mja.com.au)
  • Conclusions: The results of this study demonstrate the interest of homeopathic medicines for the prevention and treatment of migraine attacks in children. (researchgate.net)
  • RESULTS: A total of 123 patients (124 eyes) were included in this study. (eyehospital.nl)
  • ToxNav germline genetic testing and PROMinet digital mobile application toxicity monitoring: results of a prospective single centre clinical utility study (PRECISE STUDY). (ox.ac.uk)
  • This lack of diversity in study populations can lead to limited generalizability of results to other populations and eventually worsen healthcare disparities. (cdc.gov)
  • and clinical examinations, community surveys, and prospective epidemiologic studies of exposed populations. (cdc.gov)
  • Another element of clinical utility is transferability of the test to all populations, especially to people of various racial/ethnic groups and people who are medically underserved. (cdc.gov)
  • The NHLBI leads or sponsors studies for patients who have heart, lung, blood, or sleep related diseases or disorders. (nih.gov)