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  • acute
  • The clinical hallmark of HSV encephalitis has been the acute onset of fever and focal neurologic (especially temporal-lobe) symptoms. (doctorslounge.com)
  • infectious
  • Ozurdex ® is indicated for the treatment of non-infectious uveitis affecting the posterior segment of the eye. (drugs.com)
  • Infectious keratitis can progress rapidly, and generally requires urgent antibacterial, antifungal, or antiviral therapy to eliminate the pathogen. (wikipedia.org)
  • trials
  • Miltefosine is primarily used for the treatment of visceral and New World cutaneous leishmaniasis, and is undergoing clinical trials for this use in several countries. (wikipedia.org)
  • viral
  • Clinical differentiation of HSV encephalitis from other viral encephalitides, focal infections, or noninfectious processes is difficult. (doctorslounge.com)
  • Quantification of FHV or FCV copy number on quantitative PCR assays can help interpretation of results, as high viral loads in clinical specimens suggest active viral replication and involvement in the disease process, whereas lower loads may be more consistent with asymptomatic carrier status. (vin.com)
  • contact lens
  • Risk factors for developing acanthmoeba keratitis include contact lens wear, use of homemade saline, exposure to contaminated water, and corneal trauma.Over 80% of cases are related to contact lens use. (harvard.edu)
  • sterile
  • If the contralateral eye requires treatment, a new applicator must be used, and the sterile field, syringe, gloves, drapes, and eyelid speculum should be changed before Ozurdex ® is administered to the other eye. (drugs.com)
  • antiviral
  • There are no specific antiviral drugs in common use at this time for FVR, although one study has shown that ganciclovir, PMEDAP, and cidofovir hold promise for treatment. (wikipedia.org)
  • ophthalmic
  • Ocular Therapeutix™, Inc. (NASDAQ: OCUL), a biopharmaceutical company focused on the formulation, development, and commercialization of innovative therapies for diseases and conditions of the eye, today announced that the U.S. Food and Drug Administration (FDA) has approved DEXTENZA® (dexamethasone ophthalmic insert) 0.4mg for intracanalicular use for the treatment of ocular pain following ophthalmic surgery. (pharmiweb.com)
  • DEXTENZA® (dexamethasone ophthalmic insert) is a corticosteroid indicated for the treatment of ocular pain following ophthalmic surgery. (pharmiweb.com)
  • edema
  • Ozurdex ® (dexamethasone intravitreal implant) is indicated for the treatment of macular edema following branch retinal vein occlusion (BRVO) or central retinal vein occlusion (CRVO). (drugs.com)
  • Ozurdex ® is indicated for the treatment of diabetic macular edema. (drugs.com)
  • Migration
  • Dendritic cells (DCs) are present in the central avascular area of inflamed corneas, but the mechanisms of their migration to this location are poorly understood. (jove.com)
  • specific clinical
  • GRADE is a systematic approach to grading the strength of the total body of evidence that is available to support recommendations on a specific clinical management issue. (aao.org)
  • visceral
  • Several medical agents have some efficacy against visceral or cutaneous leishmaniasis, however, a 2005 survey concluded that miltefosine is the only effective oral treatment for both forms of leishmaniasis. (wikipedia.org)
  • efficacy
  • Treatment efficacy was evaluated in basal conditions and after 3, 6, 10 and 14 days on the basis of the following criteria: keratic injection, Tyndall phenomenon, vitreous changes, endothelial precipitates and pain severity, all according to 4-point scales. (biomedsearch.com)
  • initiation
  • Dendritic cells (DCs) are the key players involved in initiation of adaptive immune response by activating antigen-specific T cells. (jove.com)
  • Early initiation of treatment is most effective and typically requires long-term therapy. (harvard.edu)
  • disease
  • We recently reported that these peptides are highly recognized by CD8 + T cells from "naturally" protected HSV-1-seropositive healthy ASYMP individuals (who have never had clinical herpes disease). (arvojournals.org)
  • Biological DMARDs may be used when disease does not respond to other treatments. (wikipedia.org)
  • clinically
  • Clinical practice guidelines should be clinically relevant and specific enough to provide useful information to practitioners. (aao.org)
  • patients
  • For patients, DEXTENZA offers the convenience of a full course of post-surgical steroid treatment with a physician's one-time placement of a single intracanalicular insert. (pharmiweb.com)