• Glycoside hydrolases are also referred to as glycosidases. (cazypedia.org)
  • They belong to the three glycoside hydrolase Families 13, 70 and 77, forming a clan GH-H in the frame of the sequence-based classification of glycosidases. (go.jp)
  • Any member of the class of enzymes that catalyze the cleavage of the glycosidic linkage of glycosides and the addition of water to the resulting molecules. (bvsalud.org)
  • Glycoside hydrolase family 36 together with family 31 and family 27 alpha-galactosidases form the glycosyl hydrolase clan GH-D, a superfamily of alpha-galactosidases, alpha-N-acetylgalactosaminidases, and isomaltodextranases which are likely to share a common catalytic mechanism and structural topology. (wikipedia.org)
  • The family level classification is conditional on the domain being a member of the specified superfamily. (cam.ac.uk)
  • At present the α-amylase enzyme family covers 27 different enzyme specificities from hydrolases (EC 3), transferases (EC 2) and isomerases (EC 5). (go.jp)
  • The α-amylase family was originally created early in 1990s based on several crucial scientific observations, pioneering discoveries and efforts, such as sharing sequence similarities among different α-glucan-active enzymes within the same predicted fold of their catalytic domain, identifying the functionally versatile enzyme named neopullulanase and creating the classification of glycoside hydrolases (GHs) into sequence-based families. (or.jp)
  • Plant cell wall degrading enzyme modules including glycoside hydrolases, carbohydrate esterases and polysaccharide lyases were identified from over 2500 contigs. (concordia.ca)
  • A classification system for glycoside hydrolases, based on sequence similarity, has led to the definition of >100 different families. (wikipedia.org)
  • Glycoside hydrolase family 36 can be subdivided into 11 families, GH36A to GH36K. (wikipedia.org)
  • Indeed, as one of the first glycoside hydrolase families classified by hydrophobic cluster analysis, GH9 was previously known as "Cellulase Family E" [ 1 , 2 ]. (cazypedia.org)
  • In addition to GH families reflecting classification based on catalytic domains, the so-called starch-binding domains of amylolytic enzymes classified among more than 10 carbohydrate-binding module (CBM) families, like CBM20, CBM21 and others, has attracted scientific interest, too. (or.jp)
  • Other β-agarases belong to glycosyl hydrolase families 16 and 50, with all three groups containing a conserved glycoside hydrolase region responsible for catalysis (Fu and Kim 2010). (worthington-biochem.com)
  • This classification is available on the CAZy web site, and also discussed at CAZypedia, an online encyclopedia of carbohydrate active enzymes. (wikipedia.org)
  • The current state of knowledge of diversity, classification and structure-function relationship of these three types of xylanolytic carbohydrate esterases is discussed with emphasis on important aspects of their future research relevant to their industrial applications. (inrae.fr)
  • Six multidomain glycoside hydrolases (GHs), CelA (Athe_1867), CelB (Athe_1859), CelC (Athe_1857), CelD (Athe_1866), CelE (Athe_1865), and CelF (Athe_1860) are encoded in the Caldicellulosiruptor bescii glucan degradation locus (GDL). (princeton.edu)
  • LPMOs are copper-dependent enzymes (EC 1.14.99.53-56) that, with glycoside hydrolases, participate in the degradation of recalcitrant carbohydrate polymers. (slu.se)
  • exo - and endo - refers to the ability of a glycoside hydrolase to cleave a substrate at the end (most frequently, but not always the non-reducing end) or within the middle of a chain. (cazypedia.org)
  • Glycoside hydrolases cleave the glycosidic linkage between two carbohydrate moieties. (iastate.edu)
  • CATH: Protein Structure Classification Database by I. Sillitoe, N. Dawson, T. Lewis, D. Lee, J. Lees, C. Orengo is licensed under a Creative Commons Attribution 4.0 International License . (cathdb.info)
  • In silico study of Rett syndrome treatment-related genes, MECP2, CDKL5, and FOXG1 by evolutionary classification and disordered region assessment │ Int. J. Mol. (ritsumei.ac.jp)
  • In addition to enzymes from hydrolases, transferases and isomerases, it contains also some non-enzymatic proteins involved in amino acid transport. (or.jp)
  • The genome of Rhodothermus marinus DSM 4253 encodes six glycoside hydrolases (GH) classified under GH family 3 (GH3): RmBgl3A, RmBgl3B, RmBgl3C, RmXyl3A, RmXyl3B and RmNag3. (nih.gov)
  • Genome-wide analysis of whole human glycoside hydrolases by data-driven analysis in silico │ Int. J. Mol. (ritsumei.ac.jp)
  • A key step in genome recovery from metagenomic sequence data is the classification of sequences assembled from metagenomic reads into discrete units, referred to as bins. (biomedcentral.com)
  • Retaining enzymes produce a product with the same stereochemistry as the glycoside substrate , and inverting enzymes give a product with the opposite stereochemistry to the glycoside substrate. (cazypedia.org)
  • The GH19 Engineering Database: sequence diversity, substrate scope, and evolution in glycoside hydrolase family 19. (uni-stuttgart.de)
  • The specificity of α-amylase (EC 3.2.1.1), which hydrolyses the α-1,4-glucosidic linkages in starch and related α-glucans, is the best known representative of a large group of starch hydrolases and related amylolytic enzymes. (or.jp)
  • Amylase is the name given to glycoside hydrolase enzymes that break down starch into maltose molecules. (wikidoc.org)
  • Based on catalytic domain similarities, β-Agarase II of Pseudoalteromonas atlantica has been designated part of the glycosyl hydrolase 86 (GH86) family. (worthington-biochem.com)
  • Binding and thermodynamic properties of a carbohydrate binding module (CBM) and a glycoside hydrolase family 44 xyloglucanase/endoglucanase catalytic domain (CD) from Ruminococcus flavefaciens , both when separate and when linked to each other, have been quantified when binding various β-1,4-linked glucans and xylans. (iastate.edu)
  • There are several contradictory classifications of CHS isoenzymes and, as regards their evolutionary history, their origin and diversity is still a matter of debate. (biomedcentral.com)
  • This allowed us to revise and unify the fungal CHS classification and to study the evolutionary history of the CHS multigenic family. (biomedcentral.com)
  • This comprehensive multi-species analysis contributes to the classification of fungal CHS, in particular by optimizing its robustness, consensuality and accessibility. (biomedcentral.com)
  • Glycoside hydrolase family 36 also includes enzymes with α-N-acetylgalactosaminidase EC 3.2.1.49 and stachyose synthase EC 2.4.1.67 activities. (wikipedia.org)
  • This update has the advantage of being user-friendly due to the development of a dedicated website ( http://wwwabi.snv.jussieu.fr/public/CHSdb ), and it includes any correspondences with previously published classifications and mutants. (biomedcentral.com)
  • A necessary consequence of the EC classification scheme is that codes can be applied only to enzymes for which a function has been biochemically identified. (cazypedia.org)