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  • Antidepressant
  • Substituted piperazine Befuraline Fipexide Tekes K, Tothfalusi L, Malomvolgyi B, Herman F, Magyar K. Studies on the biochemical mode of action of EGYT-475, a new antidepressant. (wikipedia.org)
  • As one commenter in one of my favorite blogs recently observed, most new psych meds introduced since 1987 have been a clone of either Prozac (SSRI class antidepressant) or Clozaril ("atypical" antipsychotic). (blogspot.com)
  • party-pill
  • In 2007 piperazine based party-pill formulations started to become widely available nationwide which has caused concern with local authorities such as Health Canada and subsequently BZP has gained much media attention in 2008. (wikipedia.org)
  • Zealand
  • A ban was intended to come into effect in New Zealand on December 18, 2007, but the law change did not go through until the following year, and the sale of BZP and the other listed piperazines became illegal in New Zealand as of 1 April 2008. (wikipedia.org)
  • atoms
  • Piperazine (/paɪˈpɛrəziːn/) is an organic compound that consists of a six-membered ring containing two nitrogen atoms at opposite positions in the ring. (wikipedia.org)
  • Antihistamines
  • Cetirizine and levocetirizine belong to the piperazine class of antihistamines and, like other second generation antihistamines, are considered to be nonsedating. (nih.gov)
  • There is no information about cross reactivity among the various antihistamines after clinically apparent hepatotoxicity, but switching to another agent with a different structure and belonging to a separate class is probably safe. (nih.gov)
  • Loratadine, a member of the piperidine class of antihistamines, has gotten relatively positive reviews in particular for the treatment of feline itchy skin. (marvistavet.com)
  • In such trials, several antihistamines of different classes are used sequentially in hoping to find one that was especially effective. (marvistavet.com)
  • pharmaceutical
  • Blog author Daniel Carlat (mentioned here previously) is a psychiatrist in the Boston area who has taken up the noble cause of getting the pharmaceutical industry out of the continuing medical education (CME) business. (blogspot.com)
  • 6H2O, which melts at 44 °C and boils at 125-130 °C. Two common salts in the form of which piperazine is usually prepared for pharmaceutical or veterinary purposes are the citrate, 3C4H10N2.2C6H8O7 (i.e. containing 3 molecules of piperazine to 2 molecules of citric acid), and the adipate, C4H10N2.C6H10O4 (containing 1 molecule each of piperazine and adipic acid). (wikipedia.org)
  • carbon
  • Piperazine readily absorbs water and carbon dioxide from the air. (wikipedia.org)
  • Amine blends that are activated by concentrated piperazine are used extensively in commercial CO2 removal for carbon capture and storage (CCS) because piperazine advantageously allows for protection from significant thermal and oxidative degradation at typical coal flue gas conditions. (wikipedia.org)
  • Journal
  • Even so, the majority of the early work with the piperazines were investigations into their potential use as antihelminthics with the earliest clinical trials in the literature relating to piperazine being articles in the British Medical Journal in the 1950s. (wikipedia.org)
  • especially
  • Meclizine is sometimes combined with opioids, especially ones of the open-chain class like methadone, dextropropoxyphene, and dipipanone (originally combined with meclizine's parent drug cyclizine, the brand name of this combination being Diconal). (wikipedia.org)
  • Often
  • If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco. (allinahealth.org)
  • give
  • Preparation of the pyridylpiperazine moiety starts by aromatic displacement of chlorine from 2-Chloro-3-nitropyridine by piperazine to give 3. (wikipedia.org)
  • structurally
  • These range from the hepatoxic brevianamide F (cyclo(L-Trp-L-Pro)) to the annulated tremorogenic verruculogen and the spiro-annulated spirotryprostatin B which represent a promising class of antimitotic arrest agents, to the structurally complex (+)-stephacidin A, a bridged 2,5-diketopiperazine that possess a unique bicyclo[2.2.iazaoctane core ring system and is active against the human colon HCT-116 cell line. (wikipedia.org)
  • Zealand
  • In late June 2007, BZP was classed as a Class C drug in New Zealand and its availability was banned by a law passed on 13 March 2008, with a six-month amnesty period. (wikipedia.org)
  • A ban was intended to come into effect in New Zealand on December 18, 2007, but the law change did not go through until the following year, and the sale of BZP and the other listed piperazines became illegal in New Zealand as of 1 April 2008. (wikipedia.org)
  • known
  • 2,5-Diketopiperazine, also known as piperazine-2,5-dione and as the cyclodipeptide cyclo(Gly-Gly), is an organic compound and the smallest cyclic dipeptide that consists of a six-membered ring containing two amide linkages where the two nitrogen atoms and the two carbonyls are at opposite positions in the ring. (wikipedia.org)
  • drug
  • Class A drug . (drugs-forum.com)
  • Class C. A hallucinogenic, dance drug for clubbers. (drugs-forum.com)
  • Class A. Hallucinogenic drug originally synthesised by a German chemist in 1938. (drugs-forum.com)
  • Class B drug. (drugs-forum.com)
  • Class C drug. (drugs-forum.com)
  • Passed in 1996 under Prime Minister Jean Chrétien's government, it repeals the Narcotic Control Act and Parts III and IV of the Food and Drug Act and establishes eight Schedules of controlled substances and two Classes of precursors. (wikipedia.org)
  • Meclizine is sometimes combined with opioids, especially ones of the open-chain class like methadone, dextropropoxyphene, and dipipanone (originally combined with meclizine's parent drug cyclizine, the brand name of this combination being Diconal). (wikipedia.org)
  • treatment
  • The reports, published in JAMA , recommend a comprehensive effort to reduce public health risks while improving patient care, including better training for prescribers, pain management treatment assessment, personal responsibility and public education. (drugs-forum.com)