LipoproteinsVLDLTriglyceridesDigested lipidsRemnantsMetabolismEnterocytesCholesterolLipid emulsionsTriglycerideRetention diseaseEndoplasmic reticulumProteinsCompositionParticlesAdiposeIntestinalRemnantMicellesLiverSAR1BLactealsHypertriglyceridemiaMeSHBloodApolipoproteinCardiacDensityDisordersMainPresenceMajorSpecificPeopleLevelsSample
Lipoproteins8
- While circulating in blood, chylomicrons exchange components with high-density lipoproteins (HDL). (wikipedia.org)
- The main difference between chylomicrons and micelles is that chylomicrons are lipoproteins having a core of t riglycerides and cholesterols and a coat made of apolipoproteins and phospholipids , whereas micelles are globules of lipid molecules that are arranged in a spherical form in an aqueous solution. (pediaa.com)
- Chylomicrons are lipoproteins having a core of triglycerides and cholesterols and a coat of apolipoproteins and phospholipids. (pediaa.com)
- Moreover, chylomicrons are the largest of the lipoproteins. (pediaa.com)
- Lipoprotein disorders can be described as abnormalities in the level of the lipids, which include cholesterol and triglycerides, or as abnormalities in the levels of lipoproteins that include LDL , HDL, VLDL and chylomicrons . (wikidoc.org)
- It is produced in the liver and while a chylomicron is also a form of lipoprotein, there are 4 other types of lipoproteins which play an important role in fat metabolism, transport and utilization. (healthhype.com)
- This gene encodes s receptor in the endoplasmic reticulum, which plays a role in the export of large pre-chylomicrons and pre-very low density lipoproteins (pre-VLDLs). (nih.gov)
- In abetalipoproteinemia (Bassen-Kornzweig syndrome), virtually no LDL cholesterol is present, and the body cannot make chylomicrons and very-low-density lipoproteins (VLDL). (msdmanuals.com)
VLDL4
- In the former, the excess TGs are carried in very low-density lipoprotein (VLDL) versus whereas in the latter they are carried in VLDL and chylomicrons. (acc.org)
- While VLDL is believed to be atherogenic, similar to LDL, elevated chylomicrons impart an increased risk of acute pancreatitis. (acc.org)
- Secondly, Fredrickson's classification of hyperlipoproteinemia s took into consideration the elevation in chylomicrons , LDL , VLDL but did not include abnormalities in HDL levels. (wikidoc.org)
- Metabolic fate of chylomicrons and VLDL, the metabolism of HDL. (muni.cz)
Triglycerides10
- These triglycerides, along with phospholipids and cholesterol, are added to apolipoprotein B48 to form immature chylomicrons. (wikipedia.org)
- The triglycerides are then combined with phospholipids, cholesteryl esters, and apolipoprotein B48 (ApoB48) to form a nascent chylomicron. (wikipedia.org)
- Nascent chylomicrons are composed primarily of triglycerides (85%) and contain some cholesterol and cholesteryl esters. (wikipedia.org)
- Chylomicron is in particulate form of lipoprotein, which is responsible for transporting exogenous cholesterol and triglycerides from the small intestine to the adipose tissue after the meal. (labpedia.net)
- Chylomicron is a spherical particle with a core of triglycerides surrounded by a monolayer of phospholipids, cholesterol, and lipoprotein. (labpedia.net)
- Chylomicrons also play a crucial role in the transportation of dietary triglycerides to skeletal muscles and adipose tissue. (pediaa.com)
- Thus, chylomicrons not only aid in the distribution of dietary triglycerides but also assist in preventing their accumulation in the body. (pediaa.com)
- Type I is a rare disorder characterized by severe elevations in chylomicrons and extremely elevated triglycerides, always reaching well above 1000 mg/dL and not infrequently rising as high as 10,000 mg/dL or more. (medscape.com)
- Chylomicrons are very large particles that mainly carry triglycerides (fatty acids from your food). (harvard.edu)
- These chylomicrons do not only carry cholesterol but it also carries other types of fats like triglycerides and phospholipids. (healthhype.com)
Digested lipids1
- It is important to note that, unlike digested carbohydrates (in the form of monosaccharides) and proteins (in the form of amino acids), digested lipids (in the form of chylomicrons) bypass the hepatic portal system, avoiding first pass metabolism. (wikipedia.org)
Remnants1
- When a large portion of the triglyceride core has been hydrolyzed, chylomicron remnants are formed and are taken up by the liver, thereby also transferring dietary fat to the liver. (wikipedia.org)
Metabolism2
- Differential associations between plasma concentrations of insulin and glucose and intestinal expression of key genes involved in chylomicron metabolism. (harvard.edu)
- Chylomicron-like lipid emulsions, resembling chylomicrons in composition, size and metabolism were prepared in the presence of [125 I]Aβ1-40. (iospress.com)
Enterocytes2
- SAR1B gene mutations cause the retention of chylomicrons within enterocytes and prevent their release into the bloodstream. (medlineplus.gov)
- These chylomicrons exit the enterocytes by exocytosis. (pediaa.com)
Cholesterol3
- Chylomicron retention disease is an inherited disorder that impairs the normal absorption of fats, cholesterol, and certain vitamins from food. (medlineplus.gov)
- Chylomicrons are needed to absorb fat-soluble vitamins and carry fats and cholesterol from the small intestine into the bloodstream . (medlineplus.gov)
- When cholesterol is absorbed from the gut, it is transported in the form of a chylomicron from the intestinal lacteals, through the lymphatic system and emptied into the blood stream. (healthhype.com)
Lipid emulsions1
- Chylomicrons and lipid emulsions were labeled with [ 3 H]triolein, injected into mice, and appearance in plasma of [ 3 H]oleic acid was estimated, either through a steady-state approach or by compartmental modeling. (diabetesjournals.org)
Triglyceride4
- Chylomicrons transport lipids absorbed from the intestine to adipose, cardiac, and skeletal muscle tissue, where their triglyceride components are hydrolyzed by the activity of the lipoprotein lipase, allowing the released free fatty acids to be absorbed by the tissues. (wikipedia.org)
- Once triglyceride stores are distributed, the chylomicron returns APOC2 to the HDL (but keeps APOE), and, thus, becomes a chylomicron remnant, now only 30-50 nm. (wikipedia.org)
- Triglyceride is the major component of the chylomicron. (labpedia.net)
- If Triglyceride concentration is 25-200 mg/dL, then Chylomicron Electrophoresis testing will be added. (wardelab.com)
Retention disease7
- The features of chylomicron retention disease primarily affect the gastrointestinal system and nervous system. (medlineplus.gov)
- Chylomicron retention disease begins in infancy or early childhood. (medlineplus.gov)
- Other features of chylomicron retention disease develop later in childhood and often impair the function of the nervous system. (medlineplus.gov)
- Chylomicron retention disease is a rare condition with approximately 50 cases described worldwide. (medlineplus.gov)
- Mutations in a gene called SAR1B cause chylomicron retention disease. (medlineplus.gov)
- Impaired chylomicron transport causes severely decreased absorption (malabsorption) of dietary fats and fat-soluble vitamins, leading to nutritional and developmental problems in people with chylomicron retention disease. (medlineplus.gov)
- Charcosset M, Sassolas A, Peretti N, Roy CC, Deslandres C, Sinnett D, Levy E, Lachaux A. Anderson or chylomicron retention disease: molecular impact of five mutations in the SAR1B gene on the structure and the functionality of Sar1b protein. (medlineplus.gov)
Endoplasmic reticulum2
- Chylomicron forms in the endoplasmic reticulum of intestinal epithelial cells. (labpedia.net)
- Chylomicrons are made in the endoplasmic reticulum and later processed in the Golgi complex. (pediaa.com)
Proteins2
- Immature chylomicrons are transported from the smooth ER to the Golgi apparatus via SAR1B proteins, where they are processed, resulting in mature chylomicrons. (wikipedia.org)
- Hesse D, Jaschke A, Chung B, Schurmann A. Trans-Golgi proteins participate in the control of lipid droplet and chylomicron formation. (medlineplus.gov)
Composition1
- The scientists want to influence the size and composition of chylomicrons, because these characteristics dictate the fate of nutraceuticals encapsulated in the chylomicrons. (eurekalert.org)
Particles2
- Large chylomicrons have a diameter of about 1000 nm, while the smallest particles have a diameter of 75 nm to 200 nm. (pediaa.com)
- The Airfuge ® Air-Driven ultracentrifuge offers a simple, rapid method for removing chylomicrons (fat particles in lipemic samples) for accurate lipemic clarification results. (beckman.com)
Adipose4
- Chylomicron is responsible for transporting the dietary fats from the small intestine to the tissue-like adipose, cardiac and skeletal muscles. (labpedia.net)
- Chylomicron transport fats to adipose tissue and muscles. (labpedia.net)
- Chylomicrons transport hydrophobic lipids from the small intestine to adipose, skeletal, and cardiac muscle tissue, while micelles help in the absorption of lipids and fat-soluble vitamins such as vitamins A, K, D, and E. (pediaa.com)
- The adipose tissue and liver break down these chylomicrons by the action of the enzyme lipoprotein lipase. (healthhype.com)
Intestinal1
- Intestinal scavenger receptor class B type I as a novel regulator of chylomicron production in healthy and diet-induced obese states. (harvard.edu)
Remnant2
- The three stages of the chylomicron are nascent, mature, and remnant. (wikipedia.org)
- ApoB48 and APOE are important to identify the chylomicron remnant in the liver for endocytosis and breakdown. (wikipedia.org)
Micelles5
- Micelles and chylomicrons are two such globules that take the shape of a sphere. (pediaa.com)
- Both chylomicrons and micelles are fat globules. (pediaa.com)
- In brief, chylomicrons and micelles are fat globules having a hydrophobic core and a hydrophilic coat. (pediaa.com)
- Specifically, using both cell culture and animal models, Xiao and colleagues will design lipid nanoparticles at three stages: From nano-emulsion droplets containing nutraceuticals, to mixed micelles and finally to chylomicrons. (eurekalert.org)
- We're basically utilizing what already happens in our bodies all the time, but introducing food-grade nano-emulsion systems that can influence the nature of mixed micelles as well as chylomicrons," says Xiao. (eurekalert.org)
Liver1
- The remaining fat molecules are absorbed by chylomicrons, which then transport them to the liver. (pediaa.com)
SAR1B1
- The SAR1B gene provides instructions for making a protein that is needed for the transport of molecules called chylomicrons. (medlineplus.gov)
Lacteals1
- Mature chylomicrons are secreted through the basolateral membrane into the lacteals, where they join lymph to become chyle. (wikipedia.org)
Hypertriglyceridemia1
- The hyperchylomicronemia syndrome is a disorder characterized by extreme hypertriglyceridemia, the presence of chylomicrons, and one or more of the following clinical manifestations: eruptive xanthomas, lipaemia retinalis, hepatosplenomegaly, recurrent abdominal pain, and/ or acute pancreatitis. (wikipedia.org)
MeSH1
- Chylomicrons" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (harvard.edu)
Blood3
- There they are reassembled into chylomicrons and absorbed into blood circulation through the lymph system. (eurekalert.org)
- The chylomicron-like emulsions containing Aβ were then injected into a lateral ear vein of conscious rabbits and blood sampled at regular intervals up to … 30 mins. (iospress.com)
- The rationale behind fasting is to eliminate chylomicrons in the blood. (medscape.com)
Apolipoprotein1
- Apolipoprotein (apo) B-48 is important for the formation of chylomicrons. (labpedia.net)
Cardiac1
- Chylomicron provides energy to the cardiac muscles and skeletal muscles. (labpedia.net)
Density1
- Apo E also plays an important role in the formation of very low density lipoprotein and chylomicrons. (thermofisher.com)
Disorders1
- There are some disorders in which chylomicrons are involved. (wikipedia.org)
Main1
- What is the main function of the chylomicron? (labpedia.net)
Presence1
- Chylomicron Qualitative Test is a urine test that checks for the presence of chyle (a milky substance) in the urine. (redcliffelabs.com)
Major2
- This graph shows the total number of publications written about "Chylomicrons" by people in Harvard Catalyst Profiles by year, and whether "Chylomicrons" was a major or minor topic of these publication. (harvard.edu)
- What is a major component of chylomicron? (labpedia.net)
Specific1
- A protein specific to chylomicrons is ApoB48. (wikipedia.org)
People1
- Below are the most recent publications written about "Chylomicrons" by people in Profiles. (harvard.edu)
Levels3
- The chylomicron-qualitative-urine diagnostic test measures fat levels and chyle in the urine. (redcliffelabs.com)
- A. Being performed on the urine sample, Chylomicron Qualitative Urine Test is used to measure fat levels in the urine and diagnose chyle in urine early. (redcliffelabs.com)
- Chylomicron Qualitative, Urine is one urine test that doctors recommend to measure the levels of fat content in urine. (redcliffelabs.com)
Sample1
- So, you can get the Chylomicron Urine Test with us at Rs 600 with a free home sample collection. (redcliffelabs.com)