Chorea. Medical search. Frequent questions

citation needed] Huntington's disease is a neurodegenerative disease and most common inherited cause of chorea. (wikipedia.org)
The condition was formerly called Huntington's chorea but was renamed because of the important non-choreic features including cognitive decline and behavioural change. (wikipedia.org)
The FDA announced Aug. 15 that it has approved Prestwick Pharmaceuticals Inc.'s new drug Xenazine (generic name tetrabenazine) for the treatment of chorea in people with Huntington's disease, heralding the first treatment to receive U.S. approval for any of the disease's symptoms ( Medical News Today , Aug. 18). (aapc.com)
Chorea itself isn't life-threatening, but it could be a sign of a neurological disease such as Huntington's disease . (clevelandclinic.org)
About 30,000 people in the United States have Huntington's disease (a genetic condition that causes chorea). (clevelandclinic.org)
Chorea is the most common symptom of Huntington's disease. (clevelandclinic.org)
There are two types of chorea, Huntington's chorea and Sydenham's chorea. (luriechildrens.org)
Huntington's chorea appears in adults and is hereditary, progressive, and ultimately fatal. (luriechildrens.org)
Chorea is a primary feature of Huntington's disease, a progressive, hereditary movement disorder that appears in adults, but it may also occur in a variety of other conditions. (brainfacts.org)
Treatment for Huntington's disease is supportive, while treatment for Syndenham's chorea usually involves antibiotic drugs to treat the infection, followed by drug therapy to prevent recurrence. (brainfacts.org)
Huntington's chorea, or Huntington's disease, named after Ohio physician George Huntington in 1872, is an inherited disorder characterized by abnormal body movements called chorea, and loss of memory. (writework.com)
Understanding and treating Huntington's chorea can help save countless lives and individuals. (writework.com)
Huntington's Chorea" WriteWork.com. (writework.com)
Huntington's Disease Huntington's disease, or Huntngton's chorea, is a genetic disease that causes selective neural cell death, which results in chorea, or irregular, jerking movements of the limbs caused by involuntary muscle contractions, and dementia. (writework.com)
We suggest that although benign hereditary chorea and Huntington's disease may have some clinical similarities they are probably at two different loci. (bmj.com)
involuntary movements (chorea) of Huntington's disease. (ingrezza.com)
1. Neurocrine Biosciences Announces FDA Approval of INGREZZA® (valbenazine) Capsules for the Treatment of Chorea Associated With Huntington's Disease. (neurologylive.com)

Chorea (or choreia, occasionally) is an abnormal involuntary movement disorder, one of a group of neurological disorders called dyskinesias. (wikipedia.org)
Chorea refers to the involuntary jerking movements made by people with this disorder. (medlineplus.gov)
In addition to chorea, another common feature of chorea-acanthocytosis is involuntary tensing of various muscles (dystonia), such as those in the limbs, face, mouth, tongue, and throat. (medlineplus.gov)
Chorea is an involuntary abnormal movement, characterized by abrupt, brief, nonrhythmic, nonrepetitive movement of any limb, often associated with nonpatterned facial grimaces. (medscape.com)
Chorea is defined as random-appearing, continuous (while awake), involuntary movements which can affect the entire body. (rarediseases.org)
Initially, doctors may misattribute the restless movements and involuntary facial expressions of Sydenham chorea to a child being extremely fidgety, hyperactive, clumsy and/or purposely uncooperative. (rarediseases.org)
Chorea is a movement disorder that causes involuntary, irregular, unpredictable muscle movements. (clevelandclinic.org)
Chorea is an abnormal involuntary movement disorder, one of a group of neurological disorders called dyskinesias, which are caused by overactivity of the neurotransmitter dopamine in the areas of the brain that control movement. (brainfacts.org)
Intensive propulsion, involuntary muscle movements (limbs and face), muscle weakness of left upper and lower limbs, and "walk dance" in 38-year-old man with tick-borne encephalitis and chorea, Poland. (cdc.gov)
HD is the most common genetic cause of abnormal involuntary writhing movements called chorea. (tevausa.com)
Absent subthalamic nucleus inhibition enhances motor activity through the motor thalamus, resulting in abnormal involuntary movements such as dystonia, chorea, and tics. (medscape.com)
After excluding the other possible causes of chorea, phenytoin was withdrawn which resulted in a dramatic subsidence of chorea .On rechallenge with phenytoin patient again developed chorieform movements which again subsided after drug withdrawl, thus implicating phenytoin as the possible etiological agent for chorea Conclusion:Phenytoin rarely induces involuntary movements as adverse effect.During phenytoin therapy,if a patient develops involuntary movements,phenytoin toxicity should be suspected. (authorea.com)
Signs and symptoms in infants may include low muscle tone, involuntary movements (chorea), lung infections, and respiratory distress. (nih.gov)
Chorea (Greek for 'dance') refers to widespread arrhythmic involuntary movements of a forcible, jerky and restless fashion. (nih.gov)
Chorea results in involuntary movements like jerking and writhing, typically beginning in the person's fingers, feet, face, or torso. (bestmindbodyhealth.com)
Chorea is a neurological disorder characterized by abrupt, purposeless, non-rhythmic, involuntary movements that is often associated with muscle weakness and emotional lability. (cdc.gov)

Twenty percent (20%) of children and adolescents with rheumatic fever develop Sydenham's chorea as a complication. (wikipedia.org)
Rheumatic fever is no longer a major cause of chorea gravidarum (CG) and the pathophysiology of CG in current times is unclear. (medscape.com)
Sydenham chorea usually develops within weeks to months following group A beta-hemolytic streptococcal infection and may occur as an isolated finding or as a major complication of acute rheumatic fever. (rarediseases.org)
Because Sydenham chorea is a complication of rheumatic fever, some individuals will have additional symptoms of joint arthritis or arthralgia, inflammation of the heart valves causing permanent damage to the valves, and ongoing fever. (rarediseases.org)
In the United States, about 4,000 kids a year develop Sydenham chorea after having rheumatic fever . (clevelandclinic.org)
Kids and adolescents can develop Sydenham chorea after rheumatic fever, which is a complication of untreated strep throat. (clevelandclinic.org)
Around one to eight months after having rheumatic fever, children can develop Sydenham chorea (also called St. Vitus dance). (clevelandclinic.org)
Sydenham's chorea appears in about 20 percent of children and young adults as a complication of rheumatic fever, a complication of untreated strep throat or scarlet fever. (luriechildrens.org)
Syndenham's chorea occurs in a small percentage (20 percent) of children and adolescents as a complication of rheumatic fever. (brainfacts.org)
Chorea gravidarum occurs during pregnancy, often in patients who have had rheumatic fever. (merckmanuals.com)
Sydenham chorea, or rheumatic chorea, is a movement disorder that is more prevalent among young people, with a mean age at symptom onset between 8 and 9 years. (openneurologyjournal.com)
Sydenham chorea is associated with rheumatic fever and is considered the most common cause of acute chorea in children. (openneurologyjournal.com)
Sydenham chorea (SC) is one of the main diagnostic criteria for rheumatic fever. (openneurologyjournal.com)
Chorea often appears after the other manifestations of acute rheumatic fever. (cdc.gov)

These 'dance-like' movements of chorea often occur with athetosis, which adds twisting and writhing movements. (wikipedia.org)
Chorea often occurs with athetosis, which adds twisting and writhing movements. (brainfacts.org)
Athetosis (slow chorea) is nonrhythmic, slow, writhing, sinuous movements predominantly in distal muscles, often alternating with postures of the proximal limbs. (merckmanuals.com)
many experts believe that when they occur together (as choreoathetosis), athetosis is a dystonia superimposed on chorea. (merckmanuals.com)
Chorea and athetosis result from impaired inhibition of thalamocortical neurons by the basal ganglia. (merckmanuals.com)
Mutations in the myofibrillogenesis regulator gene (MR-1) causes paroxysmal non -kinesigenic dyskinesia (PNKD) characterized by episodic (paroxysmal) attacks of any combination of chorea, dystonia and athetosis (MR-1/PNKD) [1]. (medgenome.com)
Any discussion of chorea must also address the related terms athetosis, choreoathetosis, and ballism (also known as ballismus). (medscape.com)
Choreoathetosis is essentially an intermediate form (ie, a bit more rapid than the usual athetosis, slower than the usual chorea, or a mingling of chorea and athetosis within the same patient at different times or in different limbs). (medscape.com)
Given that the only difference between chorea, choreoathetosis, and athetosis is the speed of movement, some neurologists argue that the term athetosis is unnecessary and even confusing. (medscape.com)

Psychological symptoms may precede or accompany this acquired chorea and may be relapsing and remitting. (wikipedia.org)
Chorea gravidarum refers to choreic symptoms that occur during pregnancy. (wikipedia.org)
The signs and symptoms of chorea-acanthocytosis usually begin in early to mid-adulthood. (medlineplus.gov)
Additional symptoms of Sydenham chorea may include slurring of speech and difficulty maintaining steady hand grip. (rarediseases.org)
The severity of chorea and the presence of non-chorea symptoms of Sydenham chorea may vary greatly from one person to another. (rarediseases.org)
Symptoms of Sydenham chorea may appear anywhere from 1 week to 6 months following streptococcal infection. (rarediseases.org)
The abnormal movements in Sydenham chorea range from subtle symptoms, affecting coordination and tasks such as writing, to severe symptoms, disrupting walking, talking, and performing basic tasks such as dressing, eating, or simply holding objects. (rarediseases.org)
Sydenham chorea symptoms usually resolve within three weeks to six months. (rarediseases.org)
Occasionally, the symptoms of Sydenham chorea have recurred later during adult life, particularly in young women during the first trimester of pregnancy (so-called chorea gravidarum, which may represent a recurrence of Sydenham chorea in some cases). (rarediseases.org)
Metabolic and endocrine-related choreas are treated according to the cause(s) of symptoms. (brainfacts.org)
Chorea is a rare but potentially reversible neurological manifestation of coeliac disease, usually presenting insidiously and often presumed to be associated with typical gastrointestinal symptoms. (bmj.com)
We report a patient with rapidly progressive generalised chorea, but without preceding gastrointestinal symptoms, who was subsequently diagnosed with coeliac disease. (bmj.com)
We report here the case of a 14-year-old girl with symptoms of acute chorea that emerged 15 days after treatment resolution of COVID-19 (SARS-CoV-2 or severe acute respiratory syndrome coronavirus 2). (openneurologyjournal.com)
Therefore, we report here the case of a 14-year-old girl with symptoms of acute chorea that emerged 15 days after treatment resolution of COVID-19 (SARS-CoV-2). (openneurologyjournal.com)
One of the most common, and likely most noticeable symptoms, is chorea. (bestmindbodyhealth.com)
We believe that this is a first report of adult-onset Sydenham chorea accompanied with psychiatric symptoms. (elsevierpure.com)

Historically, choreas like Huntington disease and Sydenham's chorea were called Saint Vitus' dance, related to a series of social phenomena of the same name. (wikipedia.org)
Teva Pharmaceutical Industries Ltd. (NYSE and TASE:TEVA) today announced that the U.S. Food and Drug Administration (FDA) has accepted the resubmission of the New Drug Application (NDA) for SD-809 (deutetrabenazine) for the treatment of chorea associated with Huntington disease (HD). (tevausa.com)
SD-809 is being developed for the treatment of chorea associated with Huntington disease, a neurodegenerative movement disorder that impacts cognition, behavior, and movements. (tevausa.com)
In a busy movement disorder center, levodopa-induced chorea is the most common movement disorder, followed by Huntington disease (HD). (medscape.com)
This episode, 'Addition of Valbenazine to Treat Huntington Disease Chorea,' features an exclusive interview with Erin Furr-Stimming, MD, FAAN, FANA, a professor of neurology at McGovern Medical School of UTHealth Houston, and principal investigator of the phase 3 KINECT-HD studies. (neurologylive.com)
Neurocrine Biosciences) to include the treatment of chorea associated with Huntington disease (HD), offering her immediate reaction to the news. (neurologylive.com)

Chorea gravidarum (CG) is the term given to chorea occurring during pregnancy. (medscape.com)
Movement disorders rarely occur during reproductive years, therefore, clinicians are not very familiar with chorea gravidarum (CG). (medscape.com)
Though rare, a type of chorea called chorea gravidarum can occur during pregnancy. (clevelandclinic.org)

Absence of close linkage between benign hereditary chorea and the locus D4S10 (probe G8). (bmj.com)
A genetic linkage study between benign hereditary chorea and the locus D4S10 using the DNA probe G8 has shown two recombinations in five small families. (bmj.com)
Benign hereditary chorea (BHC) is a rare movement disorder that beginsin infancy or childhood. (nih.gov)

Sydenham's chorea occurs as a complication of streptococcal infection. (wikipedia.org)
A brief description of the disease Sydenham's Chorea also called St. Vitus Dance. (writework.com)
Chorea, also called Sydenham's chorea or St. Vitus dance, is the major central nervous system manifestation. (cdc.gov)

Chorea, once called St. Vitus' Dance, is characterized by brief, irregular contractions that appear to flow from one muscle to the next. (aapc.com)
disease gathered in the chapels of St. Vitus in belief that this Catholic patron saint of dancing had miraculous curative powers.1,2 This type of chorea is a movement disorder as other types of chorea are. (writework.com)

Treatment depends on the type of chorea and the associated disease. (wikipedia.org)
The prognosis for individuals with chorea varies depending on the type of chorea and the associated disease. (brainfacts.org)

In 2004, Miranda et al reported of a case of chorea associated with the use of the oral contraceptives, in which anti-basal ganglia antibodies were detected, suggesting a possible immunological basis to the pathogenesis of this disorder. (medscape.com)
We describe a case of chorea in the course of TBE in a man in Poland. (cdc.gov)
ABSTRACT Introduction:We describe a case of chorea induced by phenytoin in an young indian male. (authorea.com)

The ad hoc Committee on Classification of the World Federation of Neurology has defined chorea as "a state of excessive, spontaneous movements, irregularly timed, non-repetitive, randomly distributed and abrupt in character. (medscape.com)

The broader spectrum of paediatric autoimmune neuropsychiatric disorders associated with streptococcal infection can cause chorea and are collectively referred to as PANDAS. (wikipedia.org)
Mutations in the VPS13A gene cause chorea-acanthocytosis. (medlineplus.gov)
Depending on the underlying cause, chorea may be temporary or be ongoing and get worse over time. (clevelandclinic.org)
Autoimmune diseases (such as lupus) and hormonal disorders like hyperthyroidism and metabolic disorders such as hypoglycemia can cause chorea. (clevelandclinic.org)
There is a long list of other disorders that can cause chorea. (clevelandclinic.org)

Dozens of genetic conditions, autoimmune and infectious diseases, endocrine disorders, medications and even pregnancy can have chorea as a symptom. (clevelandclinic.org)
Dozens of genetic conditions, autoimmune diseases, metabolic disorders, infections and medications can affect basal ganglia and lead to the onset of chorea. (clevelandclinic.org)
60 should not be assumed to be senile chorea but should be thoroughly evaluated to identify the cause (eg, toxic, metabolic, autoimmune, paraneoplastic, drug-induced). (merckmanuals.com)
An Autoimmune Basis for Diabetes-Related Chorea? (elsevierpure.com)

Sydenham chorea is a major sign of acute RF. (medlineplus.gov)
A tumor or an infarct in the striatum (caudate or putamen) can cause acute unilateral chorea (hemichorea) on the opposite side of the body. (merckmanuals.com)
Case presentation: A twenty one year old indian male patient who is a known case of generalized epilepsy for past 2 years on sodium valproate presented with acute onset chorea, four days after starting phenytoin sodium with normal serum phenytoin levels. (authorea.com)

Adjusting medication dosages can treat drug-induced chorea. (brainfacts.org)

Thus, chorea is said to be a hyperkinetic movement disorder. (wikipedia.org)
Chorea is a hyperkinetic movement disorder resulting from dysfunction of striatal medium spiny neurons (MSNs), which form the main output projections from the basal ganglia. (northwestern.edu)

Here, we used whole-exome sequencing to unravel the underlying genetic cause in three unrelated individuals with a very similar and unique clinical presentation of childhood-onset chorea and characteristic brain MRI showing symmetrical bilateral striatal lesions. (northwestern.edu)
Chorea can be genetic or acquired, and often leads to a challenging diagnostic conundrum. (bmj.com)

Sydenham chorea is a movement disorder that occurs after infection with specific bacteria called group A streptococcus. (medlineplus.gov)
Sydenham chorea is caused by an infection with bacteria called group A streptococcus. (medlineplus.gov)
Sydenham chorea may be the only sign of RF in some people. (medlineplus.gov)
Sydenham chorea occurs most often in girls before puberty, but may be seen in boys. (medlineplus.gov)
Sydenham chorea usually clears up in a few months. (medlineplus.gov)
In rare cases, an unusual form of Sydenham chorea may begin later in life. (medlineplus.gov)
Sydenham chorea is a rare neurological disorder characterized by sudden onset chorea, usually in childhood. (rarediseases.org)
Sydenham chorea most often affects children over the age of 5 years and adolescents. (rarediseases.org)
The abnormal movements (chorea) that characterize Sydenham chorea usually emerge over hours, peaking within a few hours or days. (rarediseases.org)
Most of the time, kids with Sydenham chorea get better without treatment in less than two years. (clevelandclinic.org)
Sydenham chorea and chorea due to infarcts of the caudate nucleus often lessen over time without treatment. (merckmanuals.com)
We believe that the present case is worth reporting since the occurrence of Sydenham chorea as a post-COVID-19 sequela has not been described in Brazil. (openneurologyjournal.com)
Sydenham chorea is usually self-limiting and lasts on average 2 to 3 months, although cases with a duration of more than 2 years have been reported. (openneurologyjournal.com)
We report a 56-year-old man with adult-onset Sydenham chorea. (elsevierpure.com)
The present case was diagnosed as Sydenham chorea, because of the presence of arthritis, chorea, fever, increased erythrocyte sedimentation rate and elevated CRP. (elsevierpure.com)

The patient reported here is the first well documented case of anti-phospholipid antibody syndrome presenting chorea as an initial manifestation in the Japanese literature. (elsevierpure.com)

Chorea can also be induced by drugs (levodopa, anti-convulsants, and anti-psychotics) metabolic and endocrine disorders, and vascular incidents. (brainfacts.org)
Chorea due to hyperthyroidism or another metabolic cause (eg, hyperglycemia) usually lessens over time when thyroid function or blood glucose returns to normal. (merckmanuals.com)
If chorea does not subside after several weeks of metabolic control, clinicians should check for another cause such as stroke. (merckmanuals.com)

They argue a simpler nomenclature would delineate fast, intermediate, and slow chorea. (medscape.com)

Chorea is a movement disorder that occurs in many different diseases and conditions. (clevelandclinic.org)
Some people develop chorea if they have a stroke or a tumor that occurs in or near basal ganglia. (clevelandclinic.org)

Regrettably, there is currently no cure for this condition, but there are treatment and medication options for symptom management, such as prescription medications like haloperidol, tetrabenazine, amantadine, and Austedo which specifically helps with chorea. (bestmindbodyhealth.com)
The clinical diagnosis of chorea was made and haloperidol was administered with partial symptomatic improvements. (elsevierpure.com)

The NINDS supports research on movement disorders such as chorea. (brainfacts.org)
Pharmacological modulation of this pathway could offer promising etiologically targeted treatments for chorea and other hyperkinetic movement disorders. (northwestern.edu)

A 20 year old female patient with anti-phospholipid antibody syndrome who presented chorea as an initial symptom is described. (elsevierpure.com)

this form of severe chorea is referred to as ballism, or ballismus. (wikipedia.org)
In some extremely rare cases (less than 2 percent), severe muscle weakness, irritability, or confusion may be profound and affected children may become bedridden, a condition sometimes referred to as paralytic chorea. (rarediseases.org)
Hemiballismus may be considered a severe form of chorea. (merckmanuals.com)
If treatment before delivery is necessary because chorea is severe, barbiturates are indicated because they have fewer fetal risks than other drugs used to manage chorea. (merckmanuals.com)
Chorea is a severe, distressing, movement disorder characterised by excessive, purposeless movements of the limbs, head and orofacial muscles in a generalised and irregularly-timed fashion. (rcpe.ac.uk)
Ballism or ballismus is considered a very severe form of chorea in which the movements have a violent, flinging quality. (medscape.com)
Currently, ballism should be viewed as a severe form of chorea. (medscape.com)

Chorea is a neurological symptom that originates in an area of the brain called basal ganglia, which are collections of nerve cells deep inside the brain that control movement. (clevelandclinic.org)
The identification of PDE10A mutations as a cause of chorea further motivates the study of cAMP signaling in MSNs and highlights the crucial role of striatal cAMP signaling in the regulation of basal ganglia circuitry. (northwestern.edu)

On admission, neurological examination revealed dementia, emotional incontinence, abnormal behavior and chorea in four limbs. (elsevierpure.com)

Chorea involves both proximal and distal muscles. (medscape.com)

Chorea is usually a symptom of another disorder. (clevelandclinic.org)

eg, risperidone , olanzapine ), and dopamine -depleting drugs (eg, deutetrabenazine , reserpine [no longer available in US], tetrabenazine ) can be used to treat chorea. (merckmanuals.com)

therefore, the pathophysiology of HD as it applies to chorea is the focus of the discussion that follows. (medscape.com)

The disorder can make you look like you're dancing (the word chorea comes from the Greek word for "dance") or look restless or fidgety. (clevelandclinic.org)

is the most common degenerative disorder causing chorea. (merckmanuals.com)

The term hemichorea refers to chorea of one side of the body, such as chorea of one arm but not both (analogous to hemiballismus). (wikipedia.org)

This is not an etiologically or pathologically distinct entity but rather a generic term for chorea of any cause starting during pregnancy. (medscape.com)
In 1950, Beresford and Graham postulated that, "It may be that pregnancy lowers the resistance of a patient who is inherently susceptible to chorea. (medscape.com)
If pregnancy is the cause of the chorea, it may appear during the first three months of pregnancy and stop shortly after the birth of the baby. (clevelandclinic.org)

As the disease progresses, so does the degeneration of this area of the brain, thus explaining why chorea becomes more and more intense over time. (bestmindbodyhealth.com)

Hypermetabolism in bilateral caudate nuclei, especially on the right, was found on FDG-PET study, which was compatible with his left side-dominant chorea and might reflect inflammation as a nature. (elsevierpure.com)

Diseases6

Chemicals and Drugs1

Psychiatry and Psychology1

Huntington's17

Involuntary16

Rheumatic14

Athetosis9

Symptoms16

Huntington6

Gravidarum3

Hereditary3

Sydenham's Chorea3

Vitus2

Type of chorea2

Case of chorea3

Neurology1

Cause chorea5

Autoimmune4

Acute3

Drug-induced1

Hyperkinetic movement disorder2

Genetic2

Sydenham Chorea15

Manifestation1

Metabolic3

Slow chorea1

Occurs2

Haloperidol2

Movement disorders2

Syndrome1

Severe7

Basal2

Behavior1

Distal muscles1

Symptom1

Tetrabenazine1

Pathophysiology1

Fidgety1

Degenerative1

Hemiballismus1

Pregnancy3

Disease1

Bilateral1