Checkpoint Kinase 2Protein-Serine-Threonine KinasesProtein KinasesCell Cycle ProteinsDNA DamageAtaxia Telangiectasia Mutated ProteinsGenes, cdcG2 PhaseCell CycleMitosisM Phase Cell Cycle CheckpointsPhosphorylationS PhaseCell Cycle CheckpointsProtein Kinase Inhibitorscdc25 PhosphatasesMutationPhosphatidylinositol 3-KinasesDNA ReplicationHydroxyureaSaccharomyces cerevisiae ProteinsMAP Kinase Signaling SystemCDC2 Protein KinaseDNA-Binding ProteinsSpindle ApparatusSchizosaccharomyces pombe ProteinsG2 Phase Cell Cycle CheckpointsTumor Suppressor ProteinsNuclear ProteinsSchizosaccharomycesCell Line, TumorIntracellular Signaling Peptides and ProteinsDNA RepairS Phase Cell Cycle CheckpointsKinetochoresSignal TransductionSaccharomyces cerevisiaeTumor Suppressor Protein p53Calcium-Calmodulin-Dependent Protein KinasesRNA, Small InterferingApoptosisProtein-Tyrosine Kinasessrc-Family KinasesHeLa CellsProtein BindingRadiation, IonizingEnzyme ActivationNocodazoleBreast NeoplasmsCyclin-Dependent KinasesModels, BiologicalMolecular Sequence DataBlotting, WesternCell LineCdc20 Proteinsp38 Mitogen-Activated Protein KinasesG1 PhaseProtein Kinase CCell DivisionMethyl MethanesulfonateRNA InterferenceAurora KinasesDNA Breaks, Double-StrandedCell SurvivalGenomic InstabilityUltraviolet RaysNeoplasmsAmino Acid SequenceHistonesCyclic AMP-Dependent Protein KinasesAntineoplastic AgentsMitogen-Activated Protein Kinase 1Early Detection of CancerCyclin BFungal ProteinsTransfectionChromosome SegregationDNA, FungalProtein Structure, TertiaryMitogen-Activated Protein Kinase KinasesJNK Mitogen-Activated Protein Kinasesp21-Activated KinasesMitogen-Activated Protein Kinase 3Gamma RaysCell ProliferationColonic NeoplasmsHCT116 CellsCell NucleusProstatic NeoplasmsSerineRNA, MessengerBase SequenceEnzyme InhibitorsTumor Cells, CulturedStaurosporineImmunoblottingGene Expression Regulation, NeoplasticProto-Oncogene ProteinsMAP Kinase Kinase KinasesGene Deletion