• Cetacaine is a benzocaine-based anesthetic that also contains other active ingredients that include butamben and tetracaine hydrochloride. (wikipedia.org)
  • This is due to benzocaine causing the immediate anesthetic effect, while butamben and tetracaine hydrochloride causes the extended effect of Cetacaine. (wikipedia.org)
  • Cetacaine also contains small amounts of benzalkonium chloride at 0.5% and 0.005% of cetyl dimethyl ethyl ammonium bromide all in a bland water-soluble base. (wikipedia.org)
  • In 2006 the FDA has announced that benzocaine-based anesthetics can cause methemoglobinemia and with that listed warnings and precautions to take when dealing with benzocaine based drugs. (wikipedia.org)
  • The U.S. Food and Drug Administration reported in April 2011 that use of benzocaine in products such as Anbesol , Orajel , Baby Orajel , Orabase , Hurricaine and other store-brand gels and liquids as well as sprays Cetacaine, Exactacain, and Topex can cause methemoglobinemia, a blood-related ailment that can be fatal. (klinespecter.com)
  • Cetacaine is produced by the company Cetylite Industries, Inc. and they provide Cetacaine in three forms: liquid, gel, and spray. (wikipedia.org)
  • The spray form of Cetacaine is also used to help prevent gagging in the patient. (wikipedia.org)
  • Spray: Cetacaine spray should be applied for only one second and dosage should not exceed an application spray longer than 2 seconds. (wikipedia.org)
  • The liquid and other forms of Cetacaine should not be administered via injection or used under dentures, on eyes or with patients with a cholinesterase deficiency. (wikipedia.org)
  • Benzocaine-based anesthetics (which includes Cetacaine) have started to come scrutiny by the FDA. (wikipedia.org)
  • From looking at the patent bank the only research that has occurred around Cetacaine has been with certain medical procedures that use Cetacaine as an anesthetic or new dispensing containers or methods. (wikipedia.org)
  • Benzocaine is used by physicians in medical procedures to numb the mucous membranes in the mouth and throat. (klinespecter.com)
  • Hundreds of cases have been reported with most occurring in children two years old or younger whose parents administered benzocaine gel for teething, according to an April 2011 warning issued by the U.S. Food and Drug Administration (FDA). (klinespecter.com)
  • The FDA advised that benzocaine products not be used for children younger than two years old except under the advice and supervision of a health care professional. (klinespecter.com)
  • It said benzocaine products should be stored out of the reach of children. (klinespecter.com)
  • Kline & Specter, PC, with more than 35 attorneys, several of whom are also doctors, is among the leading law firms in the nation to investigate and litigate potential benzocaine cases. (klinespecter.com)
  • This effect is due to the rapid onset, but short duration of action of Benzocaine coupled with the slow onset, but extended duration of Tetracaine HCI and bridged by the intermediate action of Butamben. (nih.gov)
  • Cetacaine is a benzocaine-based anesthetic that also contains other active ingredients that include butamben and tetracaine hydrochloride. (wikipedia.org)
  • This is due to benzocaine causing the immediate anesthetic effect, while butamben and tetracaine hydrochloride causes the extended effect of Cetacaine. (wikipedia.org)
  • The combination of benzocaine (short duration for a quick onset in 30 seconds), tetracaine hydrochloride (slow onset for an extended duration of 30 to 60 minutes) and butamben (intermediate action bridge) acts by reversibly blocking nerve conduction. (oralscience.ca)
  • Each 200 mg dose of Cetacaine (Spray residue, Liquid or Gel) contains 28 mg of benzocaine, 4 mg of butamben and 4 mg of tetracaine HCl. (horsemedicare.com)
  • Cetacaine also contains small amounts of benzalkonium chloride at 0.5% and 0.005% of cetyl dimethyl ethyl ammonium bromide all in a bland water-soluble base. (wikipedia.org)
  • Cetacaine Spray is indicated for use to control pain or gagging. (nih.gov)
  • Cetacaine Spray should be applied for approximately one second or less for normal anesthesia. (nih.gov)
  • An appropriate pediatric dosage has not been established for Cetacaine Spray or Cetacaine Liquid. (nih.gov)
  • Do not use Cetacaine Spray or Cetacaine Liquid to treat infants or children younger than 2 years. (nih.gov)
  • Cetacaine is produced by the company Cetylite Industries, Inc. and they provide Cetacaine in three forms: liquid, gel, and spray. (wikipedia.org)
  • The spray form of Cetacaine is also used to help prevent gagging in the patient. (wikipedia.org)
  • Spray: Cetacaine spray should be applied for only one second and dosage should not exceed an application spray longer than 2 seconds. (wikipedia.org)
  • Cetacaine is a topical anesthetic indicated for the production of anesthesia of all accessible mucous membrane except the eyes. (nih.gov)
  • Routine precaution for the use of any topical anesthetic should be observed when using Cetacaine. (horsemedicare.com)
  • Severe methemoglobinemia linked to gel-type topical benzocaine use: a case report. (nih.gov)
  • Cetacaine can have interaction with other drugs being taken by patients one of the interactions that can lead to methemoglobinemia is the interaction with sodium nitrate as well as prilocaine, which can lead to severe illness or death. (wikipedia.org)
  • In 2006 the FDA has announced that benzocaine-based anesthetics can cause methemoglobinemia and with that listed warnings and precautions to take when dealing with benzocaine based drugs. (wikipedia.org)
  • One of the only studies that are current with Cetacaine is the one that the FDA is conducting surrounding the issue of patients contracting methemoglobinemia from the use of Cetacaine. (wikipedia.org)
  • On rare occasions, methemoglobinemia has been reported in connection with the use of benzocaine-containing products. (horsemedicare.com)
  • The anesthetic effect of Cetacaine can be expected to take effect in about 30 seconds and last between 30-60 minutes depending on location and application amount. (wikipedia.org)
  • From looking at the patent bank the only research that has occurred around Cetacaine has been with certain medical procedures that use Cetacaine as an anesthetic or new dispensing containers or methods. (wikipedia.org)
  • The liquid and other forms of Cetacaine should not be administered via injection or used under dentures, on eyes or with patients with a cholinesterase deficiency. (wikipedia.org)
  • Cetacaine Liquid Apply 200 mg (approximately 0.2 mL) with a cotton applicator or directly to tissue. (horsemedicare.com)
  • See Cetacaine Liquid Kit instructions for additional directions for application by Luer-lock syringe and delivery tip. (horsemedicare.com)
  • The onset of Cetacaine-produced anesthesia is rapid (approximately 30 seconds) and the duration of anesthesia is typically 30-60 minutes, when used as directed. (nih.gov)
  • Only a limited quantity of Cetacaine is required for anesthesia. (nih.gov)
  • Tissue need not be dried prior to application of Cetacaine. (nih.gov)
  • Tissue need not be dried before application of Cetacaine. (horsemedicare.com)
  • For optimal use, apply Cetacaine on two to three teeth at a time. (oralscience.ca)
  • Cetacaine Gel Dispense and apply 200 mg of gel (a bead approximately 1/4 to 1/2 inches long) by gently depressing the pump. (horsemedicare.com)
  • Benzocaine-based anesthetics (which includes Cetacaine) have started to come scrutiny by the FDA. (wikipedia.org)
  • Cetacaine in all forms is indicated to control pain and for use for surgical or endoscopic or other procedures in the ear, nose, mouth, pharynx, larynx, trachea, bronchi, and esophagus. (nih.gov)
  • Cetacaine acts quickly in about 30 seconds and can last between 30-60 minutes. (wikipedia.org)
  • The FDA also during this time started to take many Benzocaine based drugs that were not approved off the market and fining those companies they were under. (wikipedia.org)
  • Cetacaine should be applied directly to the site where pain control is required. (nih.gov)