DoxorubicinAnthracyclineChemotherapy medicationsLiposomalDaunomycinInjectionDecreaseTreatTreatmentMedicalIdarubicinChemotherapyAllergic to daunorubicinLiposomal formulationAnthracycline antibioticsCytarabineIntravenous infusionToxicityDexamethasoneAcute leukemiaMedicationsDosePrecautionsTypicallySynthesisLeukemiaSevereTell your doctorDrugsSide effectsTherapyCommonCancerWorkTest
Doxorubicin4
- citation needed] Daunorubicin is also used as the starting material for semi-synthetic manufacturing of doxorubicin, epirubicin and idarubicin. (wikipedia.org)
- Similar to doxorubicin, daunorubicin interacts with DNA by intercalation and inhibition of macromolecular biosynthesis. (wikipedia.org)
- Another form of treatment - anthracycline chemotherapy - uses doxorubicin , daunorubicin (Cerubidine), epirubicin (Ellence), and idarubicin (Idamycin). (dreamsfertility.com)
- Daunorubicin is an antineoplastic anthracycline antibiotic with actions similar to those of doxorubicin. (e-lactancia.org)
Anthracycline2
- Daunorubicin is in the anthracycline family of medication. (wikipedia.org)
- An anthracycline antineoplastic agent, daunorubicin inhibits DNA and RNA synthesis by intercalating between DNA base pairs. (medscape.com)
Chemotherapy medications2
- Daunorubicin injection must be given in a hospital or medical facility under the supervision of a doctor who is experienced in giving chemotherapy medications for cancer. (medlineplus.gov)
- Daunorubicin comes as a solution (liquid) or as a powder to be mixed with liquid to be injected intravenously (into a vein) by a doctor or nurse in a medical facility along with other chemotherapy medications. (medlineplus.gov)
Liposomal1
- A liposomal formulation known as liposomal daunorubicin also exists. (wikipedia.org)
Daunomycin1
- Daunorubicin, also known as daunomycin, is a chemotherapy medication used to treat cancer. (wikipedia.org)
Injection1
- tell your doctor and pharmacist if you are allergic to daunorubicin, any other medications, or any of the ingredients in daunorubicin injection. (medlineplus.gov)
Decrease1
- Daunorubicin can cause a severe decrease in the number of blood cells in your bone marrow. (medlineplus.gov)
Treat3
- When daunorubicin is used to treat ALL, it is usually injected once a week. (medlineplus.gov)
- citation needed] In addition to its major use in treating AML, daunorubicin is also used to treat neuroblastoma. (wikipedia.org)
- Daunorubicin has been used with other chemotherapy agents to treat the blastic phase of chronic myelogenous leukemia. (wikipedia.org)
Treatment2
- Daunorubicin may cause serious or life-threatening heart problems at any time during your treatment or months to years after your treatment has ended. (medlineplus.gov)
- Your doctor will order tests before and during your treatment to see if your heart is working well enough for you to safely receive daunorubicin. (medlineplus.gov)
Medical1
- Daunorubicin was approved for medical use in the United States in 1979. (wikipedia.org)
Idarubicin1
- 7+3 may be given using idarubicin , instead of daunorubicin. (chemoexperts.com)
Chemotherapy6
- Daunorubicin injection must be given in a hospital or medical facility under the supervision of a doctor who is experienced in giving chemotherapy medications for cancer. (medlineplus.gov)
- Daunorubicin comes as a solution (liquid) or as a powder to be mixed with liquid to be injected intravenously (into a vein) by a doctor or nurse in a medical facility along with other chemotherapy medications. (medlineplus.gov)
- Daunorubicin, also known as daunomycin, is a chemotherapy medication used to treat cancer. (wikipedia.org)
- Daunorubicin has been used with other chemotherapy agents to treat the blastic phase of chronic myelogenous leukemia. (wikipedia.org)
- Chemotherapy with daunorubicin in combination with other agents is associated with serum enzyme elevations in a proportion of patients depending upon the dose and other agents used. (nih.gov)
- Cancer treatments, from surgery, radiation therapy and chemotherapy to drugs such as daunorubicin (Cerubidine and DaunoXome) and Ixempra (ixabepilone) will all take a toll on the skin - after all, it is the body's largest organ. (paiskincare.us)
Allergic to daunorubicin2
- tell your doctor and pharmacist if you are allergic to daunorubicin, any other medications, or any of the ingredients in daunorubicin injection. (medlineplus.gov)
- Do not take daunorubicin if you are allergic to daunorubicin or to any of its ingredients. (rxwiki.com)
Liposomal formulation2
- A liposomal formulation known as liposomal daunorubicin also exists. (wikipedia.org)
- A liposomal formulation of daunorubicin is available as a first line therapy for advanced HIV related Kaposi sarcoma. (nih.gov)
Anthracycline antibiotics1
- There is no information on cross sensitivity to hepatic injury between daunorubicin and other antineoplastic agents, including anthracycline antibiotics. (nih.gov)
Cytarabine2
- How does 7+3 (cytarabine + daunorubicin) work? (chemoexperts.com)
- Typically, daunorubicin and cytarabine are both started on the same day. (chemoexperts.com)
Intravenous infusion1
- Daunorubicin should only be administered in a rapid intravenous infusion. (wikipedia.org)
Toxicity3
- However, by 1967, it was recognized that daunorubicin could produce fatal cardiac toxicity. (wikipedia.org)
- While hepatotoxicity from daunorubicin may be rare, it is likely due to direct hepatic toxicity. (nih.gov)
- Toxicity from daunorubicin may occur, which may result in disease of the heart muscle or heart failure. (rxwiki.com)
Dexamethasone1
- Drugs commonly used during remission induction therapy include dexamethasone or prednisone, vincristine, asparaginase, and daunorubicin. (medscape.com)
Acute leukemia2
Medications2
- Daunorubicin is in a class of medications called anthracyclines. (medlineplus.gov)
- Other medications may also interact with daunorubicin, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list. (medlineplus.gov)
Dose2
- ALT elevations during daunorubicin therapy are usually asymptomatic and transient and may resolve without dose modification. (nih.gov)
- Daunorubicin ends when the third dose is given on Day 3. (chemoexperts.com)
Precautions1
- See the "Daunorubicin Precautions" section. (rxwiki.com)
Typically2
- Daunorubicin is given intravenously, typically in a regimen of once daily for 3 days during induction and for two days of subsequent courses. (nih.gov)
- However, high doses of daunorubicin given in combination with other antineoplastic agents have been linked to cases of sinusoidal obstruction syndrome, typically presenting with right upper quadrant pain 10 to 30 days after the infusion, followed by weight gain, ascites and liver test abnormalities. (nih.gov)
Synthesis2
- Daunorubicin is an anthracycline that intercalates with DNA and interferes with DNA synthesis. (medscape.com)
- Daunorubicin (daw" noe roo' bi sin) is a parenterally administered, cytotoxic antibiotic which is believed to act by intercalating between DNA base pairs and uncoiling the DNA helix, which results in inhibition of DNA synthesis and apoptosis of rapidly dividing cells. (nih.gov)
Leukemia2
- Small volumes of daunorubicin can be wrapped up in these minuscule pods, which can then be released into a leukemia cell-filled environment. (wikipedia.org)
- Daunorubicin is a prescription medication used to treat certain types of blood cancer, such as leukemia, in combination with other approved anticancer drugs. (rxwiki.com)
Severe2
- Daunorubicin can cause a severe decrease in the number of blood cells in your bone marrow. (medlineplus.gov)
- Local extravasation of daunorubicin causes severe local tissue injury. (nih.gov)
Tell your doctor1
- Before taking daunorubicin, tell your doctor about all of your medical conditions. (rxwiki.com)
Drugs1
- Daunorubicin belongs to a group of drugs called anthracyclines. (rxwiki.com)
Side effects1
- Serious side effects have been reported with daunorubicin. (rxwiki.com)
Therapy2
- Daunorubicin is associated with a low rate of transient serum enzyme and bilirubin elevations during therapy, but has not been implicated in cases of clinically apparent acute liver injury with jaundice. (nih.gov)
- There have been no convincing instances of acute, clinically apparent idiosyncratic liver injury with jaundice associated with daunorubicin therapy. (nih.gov)
Common1
- Daunorubicin has been used intravitreally (inside the eye) for the purposes of preventing proliferative vitreoretinopathy, a common complication following retinal detachment surgery, but has not been found to be effective and is not used for any other ophthalmic purposes at this time. (wikipedia.org)
Cancer1
- Daunorubicin treats certain types of blood cancer. (rxwiki.com)
Work2
- How well did Daunorubicin work for you? (rxwiki.com)
- Daunorubicin requires close patient observation and frequent blood lab work. (rxwiki.com)
Test1
- In many instances, it is difficult to attribute the liver test abnormalities to daunorubicin, because of the exposure to other potentially hepatotoxic agents. (nih.gov)