Cerebrosides. Medical search. Frequent questions

It is phosphorylated by ceramide kinase (CK) to form ceramide-1-phosphate or it can be glycosylated by glucosylceramide synthase to form glycosphingolipids (cerebrosides, globosides, gangliosides). (frontiersin.org)
The sphingolipids described in Sphingolipids, Steroids, Lipopolysaccharides and Related Probes-Section 13.3 include ceramides, sphingomyelins, glycosylceramides (cerebrosides) and gangliosides. (thermofisher.com)
Examples are cerebrosides and gangliosides. (brainwritings.com)
Saposin-B stimulates the hydrolysis of galacto-cerebroside sulfate by arylsulfatase A (EC 3.1.6.8), GM1 gangliosides by beta-galactosidase (EC 3.2.1.23) and globotriaosylceramide by alpha-galactosidase A (EC 3.2.1.22). (affbiotech.cn)

Cerebrosides is the common name for a group of glycosphingolipids called monoglycosylceramides which are important components in animal muscle and nerve cell membranes. (wikipedia.org)
Cerebrosides are glycosphingolipids found in the cell membranes of the neurons and the muscle cells. (brainwritings.com)

Cerebrosides containing a sulfuric ester (sulfate) group, known as sulfatides, also occur in the myelin sheath of nerves. (wikipedia.org)
In addition, ceramide can be converted to sulfatides by the action of galactosylceramide synthase followed by cerebroside sulfotransferase (CST). (frontiersin.org)

Cerebroside molecules are able form up to eight intermolecular hydrogen bonds between the polar hydrogens of the sugar and the hydroxy and amide groups of the sphingosine base of the ceramide. (wikipedia.org)
The cerebroside has a sphingosine core. (brainwritings.com)

Cerebroside sulfate, an integral constituent of the myelin sheaths surrounding neuronal axons in the brain, helps to maintain optimal neurological health. (holisticprimarycare.net)

Cerebroside synthesis can therefore give a measurement of myelin formation or remyelination. (wikipedia.org)
Cerebrosides are found in the brain and in the myelin sheath of nerve tissue. (quizlet.com)

In Krabbe disease, an enzyme needed to break down lipids, called cerebroside beta-galactosidase, is not working correctly. (msdmanuals.com)

Monoglycosyl and oligoglycosylceramides having a mono or polysaccharide bonded glycosidically to the terminal OH group of ceramide are defined as cerebrosides. (wikipedia.org)

Site‐Selective trans‐Hydrostannation of 1,3‐ and 1,n‐Diynes: Application to the Total Synthesis of Typhonosides E and F, and a Fluorinated Cerebroside Analogue. (mpg.de)

Cerebroside E, a compound found in the fruiting bodies of Hericium erinaceus, was shown to be particularly beneficial in cancer treatment. (forij.co)

The fundamental structure of a cerebroside is ceramide. (wikipedia.org)
The melting point of cerebrosides is considerably greater than physiological body temperature, >37.0 °C, giving glycolipids a paracrystalline, similar to liquid crystal structure. (wikipedia.org)
We also show that the order parameter describing the head group wobble is fully determined for each system, and it indicates a rather mobile structure for the cerebroside head group, in a variety of environments. (illinois.edu)
The structure of the cerebroside phrenosine. (quizlet.com)

Cerebrosides which contain as their polar head group a galactose moiety bound in glycosidic linkage to the hydroxyl group of ceramide. (uchicago.edu)

A 2015 study concluded that cerebroside E inhibited angiogenesis (the formation of new blood cells) in cancer cells and promoted cancer apoptosis. (forij.co)