PathologyMitochondriaProteinsIntracellular structureMembraneEukaryoticNucleusProcessesMolecular structureActinDifferentiationFunctionNanoparticleBiologyOrganization2023PathwaysSearchApoptosisCompositionOrganellesMembranesLargelyMechanismsAbsorptionProbesGeneticImmunePeriodicRibosomeSurfaceConsistsResearchersProtein structurePrinciplesInteractionsTypicallyRegulationResearchComponentsCellsMethodsMechanicalContentPredictDiameterFormMeshReviewMainFindings
Pathology1
- ABSTRACT Haematoxylin and eosin (H&E) is the most popular routine stain used in pathology laboratories for highlighting cellular structures. (who.int)
Mitochondria8
- We begin by talking about the most important cell structures (mitochondria, nucleus, endoplasmic reticulum). (fiveable.me)
- Mitochondria have a double membrane structure and use aerobic respiration to generate adenosine triphosphate (ATP), which is used throughout the cell as a source of chemical energy . (wikipedia.org)
- A large number of unicellular organisms , such as microsporidia , parabasalids and diplomonads , have reduced or transformed their mitochondria into other structures . (wikipedia.org)
- Mitochondria are commonly between 0.75 and 3 μm 2 in cross section, [9] but vary considerably in size and structure. (wikipedia.org)
- In addition to supplying cellular energy, mitochondria are involved in other tasks, such as signaling , cellular differentiation , and cell death , as well as maintaining control of the cell cycle and cell growth . (wikipedia.org)
- [20] This finding has led to general acceptance of the endosymbiotic hypothesis - that free-living prokaryotic ancestors of modern mitochondria permanently fused with eukaryotic cells in the distant past, evolving such that modern animals, plants, fungi, and other eukaryotes are able to respire to generate cellular energy . (wikipedia.org)
- In mitochondria, nucleosides are likely used in the formation or repair of DNA found in these structures, known as mitochondrial DNA. (medlineplus.gov)
- The generators in the cellular power plants are biological membranes located inside the mitochondria. (sciencedaily.com)
Proteins8
- LOC3D ( http://cubic.bioc.columbia.edu/db/LOC3d/ ) is both a weekly-updated database and a web server for predictions of sub-cellular localization for eukaryotic proteins of known three-dimensional (3D) structure. (rostlab.org)
- The web server can be used to predict sub-cellular localization for proteins for which only a predicted structure is available from threading servers. (rostlab.org)
- In the nucleus, chromosomes are thread-like structures made up of strands of DNA and the histone proteins. (microscopemaster.com)
- In this programme, you will study the structure and function of macromolecules such as proteins, nucleic acids and carbohydrates, and biological systems from cell extracts to whole organisms. (ed.ac.uk)
- It unravels the secrets of genes, which are segments of genetic material, such as DNA, containing instructions for building proteins and controlling various cellular processes. (freescience.info)
- In contrast, in many cancerous cell lines and tumors, where growth factor dysregulation is frequently at the heart of cellular transformation, the STAT proteins (in particular Stats 1, 3 and 5) are persistently tyrosine phosphorylated or activated. (nih.gov)
- In order to function, the cellular generators depend on the support of numerous highly specialized membrane proteins in the inner mitochondrial membrane. (sciencedaily.com)
- Thus, the scientists were able to demonstrate for the first time that at least two different protein translocases cooperate closely to insert proteins with complex structures into the inner mitochondrial membrane. (sciencedaily.com)
Intracellular structure1
- Two dinuclear osmium polypyridyl complexes function as convenient, easy to handle TEM contrast agents and facilitate the high-resolution visualisation of intracellular structure, particularly sub-nuclear detail. (rsc.org)
Membrane6
- The cytoplasm is a continuous network of filamentous proteinaceous structures that extends from the nucleus to the plasma membrane. (samarpanphysioclinic.com)
- An organelle (think of it as a cell's internal organ) is a membrane bound structure found within a cell. (khanacademy.org)
- The nuclear membrane, like the cell membrane, is a double-layered structure that consists of phospholipids (forming the lipid bilayer nucleus envelope). (microscopemaster.com)
- Unlike the nucleus, however, this dense structure lacks its own membrane. (microscopemaster.com)
- In addition, the structures of caveolae on the cytoplasmic surface of the cell membrane were significantly changed. (fujita-hu.ac.jp)
- In clarifying this coupled mechanism of membrane insertion, project head Dr. Martin van der Laan and his team have solved a hotly debated scientific problem and made a major contribution to our understanding of the composition and functioning of cellular power plants. (sciencedaily.com)
Eukaryotic2
- The budding yeast coevolution network captures the hierarchy of eukaryotic cellular structure and function, provides a roadmap for genotype-to-phenotype discovery, and portrays the genome as an extensively linked ensemble of genes. (biorxiv.org)
- Cellular organelles are specialized structures within eukaryotic cells that perform various essential functions to maintain the cell's integrity and carry out specific tasks. (samarpanphysioclinic.com)
Nucleus4
- As such, the nucleus consists of a number of structured elements that allow it to perform its functions. (microscopemaster.com)
- In the same way that the nucleus is the most prominent organelle of the cell, the nucleolus is the most prominent structure of the nucleus. (microscopemaster.com)
- Although the nucleolus is the most prominent (and thus visible) structures of the nucleus, its size is largely dependent on the level of ribosome production as well as the different types of molecular processes that occur in the nucleus. (microscopemaster.com)
- When the researchers disabled the force-bearing function of actin fibres, they found that the nucleus itself is also involved in counterbalancing external forces, highlighting the role of the internal structure of the nucleus in the cellular stress response. (jcnnewswire.com)
Processes4
- Creating cellular organizations fundamentally involves mimicking processes that occur in natural processes. (wikipedia.org)
- Professors Brent B. Allred, Raymond E. Miles, and Charles C. Snow have cited instances of cellular organization in terms of the telecommunications industry in Australia, specifically referring to the firm Technical Computing and Graphics (TCG) as an example due to how its processes have created successful work for partners such as Hitachi and Telstra. (wikipedia.org)
- When compared with traditional manufacturing processes, Additive Manufacturing (AM) has enabled the designers and engineers to fabricate intricate geometries having cellular structures for various applications in automotive, aerospace, biomedical, and footwear industries. (scholarsresearchlibrary.com)
- [10] Mitochondrial biogenesis is in turn temporally coordinated with these cellular processes. (wikipedia.org)
Molecular structure2
- Our cellular and molecular structure and function research interests range from computational protein folding to stem cell biology. (utoronto.ca)
- The left image shows the molecular structure of the tube. (lumenlearning.com)
Actin2
- They function in cellular movement, have a diameter of about 7 nm, and are made of two intertwined strands of a globular protein called actin (Figure 2). (lumenlearning.com)
- This enables actin to engage in cellular events requiring motion, such as cell division in animal cells and cytoplasmic streaming, which is the circular movement of the cell cytoplasm in plant cells. (lumenlearning.com)
Differentiation1
- MAPK pathways refer to various cellular functions, including cell proliferation, differentiation and migration. (springer.com)
Function5
- Modules within the network provide insight into cellular and genomic structure and function, such as genes functioning in distinct cellular compartments and DNA replication. (biorxiv.org)
- Please, add references to quantify this concept, many authors seem to use different words for the same thing -- not sure what it is, some structure with function -definitions -- perhaps there exists some easy category-theoretic description for them? (stackexchange.com)
- Each organelle has its distinct structure and function, contributing to the cell's overall metabolism, energy production, and maintenance of homeostasis. (samarpanphysioclinic.com)
- Genome stability through successive cell divisions is central to maintaining normal cellular function. (utoronto.ca)
- Topics covered include cell structure and function, DNA replication and the flow of genetic information, enzyme function, metabolism and physiology of microorganisms, plants, and animals. (sfu.ca)
Nanoparticle1
- Darkfield microscopy was employed to observe nanoparticle -cellular interactions, and within 5 min both pure and doped CeO2 began to associate with cells. (cdc.gov)
Biology1
- A non-biological entity with a cellular organizational structure (also known as a cellular organization, cellular system, nodal organization, nodal structure, et cetera) is set up in such a way that it mimics how natural systems within biology work, with individual 'cells' or 'nodes' working somewhat independently to establish goals and tasks, administer those things, and troubleshoot difficulties. (wikipedia.org)
Organization2
- Business and economics portal Society portal Systems science portal Antifragility Complexity theory and organizations Engineering of systems Enterprise modelling Flat organization Information management Hierarchical organization Organizational architecture Organizational culture Organizational structure Psychology of organizations Social group Spontaneous order Systems theory Clandestine cell system Unorganisation Schley, Don G. (November 2009). (wikipedia.org)
- New spatial technologies, such as single-cell spatial transcriptomics and high-plex spatial multiomics single-cell imaging, offer high-resolution spatial mapping of tertiary lymphoid structures and provide more details on cell types, functional states and cellular organization. (mdanderson.org)
20231
- TSUKUBA, Japan, Nov 21, 2023 - (ACN Newswire) - By giving living cells a 'nano-poke' and monitoring the resulting changes in the intra-cellular environment, researchers have gotten their first glimpse of how whole cells respond to external mechanical pressure. (jcnnewswire.com)
Pathways1
- Geneset enrichment of these findings has identified pathways significant in metabolism, immune signaling, other psychiatric disorders, neurological signaling, and cellular structure. (cdc.gov)
Search1
- Connect and share knowledge within a single location that is structured and easy to search. (stackexchange.com)
Apoptosis1
- while Stats 3 and 5 are involved in promoting cell cycle progression and cellular transformation and preventing apoptosis. (nih.gov)
Composition1
- These methods provide the spatial location and cellular composition of tertiary lymphoid structures, but they lack the resolution and depth needed for a comprehensive understanding. (mdanderson.org)
Organelles1
- It also gives the cell and its organelles structure, support, and protection. (samarpanphysioclinic.com)
Membranes1
- Further study of reactive oxygen species was conducted using analysis of cellular H2O2 generation, lipid peroxidation of cellular membranes and DNA damage. (cdc.gov)
Largely1
- Cellular structures are largely found in nature such as wood, bones, cork, honeycomb etc., due to excellent properties, for example excellent energy absorption, high strength-to-weight-ratio, and lightweight. (scholarsresearchlibrary.com)
Mechanisms1
- That ability to adapt relies on rapid feedback mechanisms to keep the cell intact and healthy, and there's growing evidence that the failure of this cellular response underlies a range of ailments, including diabetes, Parkinson's disease, heart attacks, and cancer. (jcnnewswire.com)
Absorption1
- A number of algorithms have been developed to correct for effects such as atmospheric absorption, light scattering by cellular structures and varying baseline levels. (lu.se)
Probes1
- The method uses nanoscale probes, with tips just a few billionths of a metre in size, to measure and map how force gets distributed across the cellular surface and throughout the cell. (jcnnewswire.com)
Genetic1
- This article empirically assesses a coarse-fine approach for diversity tuning in cellular Genetic Algorithms (cGAs). (aece.ro)
Immune2
- Tertiary lymphoid structures are highly organized clusters of immune cells that form in non-lymphoid tissues. (mdanderson.org)
- Together, tertiary lymphoid structures drive an antitumor immune response. (mdanderson.org)
Periodic1
- Cellular structures are made up of an interconnected network of plates (closed- cell structures), solid struts (open-cell structures) or small unit cells (periodic structures). (scholarsresearchlibrary.com)
Ribosome1
- We discuss cell structure (vacuole, ribosome, vesicle diagram) and also use a graphic to explain prokaryotes versus eukaryotes, and then we move on to what can and can't get through the phospholipid bilayer (selectively permeable). (fiveable.me)
Surface1
- These particles possess a large specific surface area which can enhance their reactivity on cellular surfaces as well as small size that allows translocation across cellular barriers once deposited in the lungs. (cdc.gov)
Consists1
- A typical cellular raft foundation consists of a series of deep reinforced concrete beams connecting a suspended slab with the bearing slab. (structurescentre.com)
Researchers2
- In this study, authors aim to present a comprehensive review of design, optimization, and AM of various cellular structure morphologies investigated by different researchers. (scholarsresearchlibrary.com)
- This review would provide a more precise understanding and the state-of-the-art of AM with the cellular structures for engineers and researchers in both academia and industrial applications. (scholarsresearchlibrary.com)
Protein structure1
- The study of protein structure and protein interactions represents another theme among group members. (utoronto.ca)
Principles1
- Structures from first principles! (structurescentre.com)
Interactions1
- They also provide insights into the interactions between tertiary lymphoid structures, cancer cells and other cells in the tumor microenvironment. (mdanderson.org)
Typically1
- A long structural system with an unstable (subcritical)post-buckling response that subsequently restabilizes typically deformsin a cellular manner, with localized buckles first forming and thenlocking up in sequence. (tue.nl)
Regulation1
- Structure-guided mutational analysis of gene regulation by the Bacillus subtilis pbuE adenine-responsive riboswitch in a cellular context. (ucdenver.edu)
Research2
- All major industries have been exploiting the benefits of cellular structures due to their prevalence over a wide range of research fields. (scholarsresearchlibrary.com)
- Furthermore, major gaps, limitations and new areas that needs to be investigated in cellular structures for AM area of research. (scholarsresearchlibrary.com)
Components1
- It serves as a barrier between the inside cellular components and the surrounding environment. (samarpanphysioclinic.com)
Cells5
- So far, studies of these cellular responses have been limited by the techniques used - for example, some methods require that cells be pre-fitted with sensors, so they can only measure a small part of the response. (jcnnewswire.com)
- The findings not only illuminate the complex intracellular mechanics of the stress response, but the discovery of different responses in cancer cells could offer a new way to distinguish healthy and cancerous cells - a diagnostic tool based on cellular mechanics. (jcnnewswire.com)
- We demonstrate the library's potential diagnostic abilities on miRNA and mRNA combinations in cell lysate and its ability to operate in a cellular environment by using beacon-like c-jun mimicking substrate in living mammalian cells. (nature.com)
- Wang worked with colleagues from the University of Pennsylvania and Emory University to develop state-of-the-art computational tools that effectively integrate histology data to create an advanced spatial profile of tumor-infiltrating T cells, B cells and plasma cells both within and outside of tertiary lymphoid structures. (mdanderson.org)
- Additionally, cellular deconvolution highlighted an enrichment in CD4 T cells and eosinophils in responders with PTSD compared to controls. (cdc.gov)
Methods1
- Traditional methods of studying tertiary lymphoid structures include histology, immunohistochemistry, multiplex immunofluorescence and flow cytometry. (mdanderson.org)
Mechanical1
- The primary functions include providing structure to the cell and mechanical resistance to deformation, and the contractile nature of the filaments aids in movement during cytokinesis. (samarpanphysioclinic.com)
Content1
- PubMed as a general reference for the access to content of the IDbases, and quote the IDR home page address, http://structure.bmc.lu.se/idbase/ . (lu.se)
Predict1
- Although, depending on the application, the overall porosity (and therefore density) and the average pore size can be controlled to some degree, the lack of control at the microstructural level makes it difficult to predict the long-term stability in structure and performance of such materials. (nature.com)
Diameter1
- and ( b ) an additively manufactured (AM) foam with the face-centered-tetragonal (FCT) lattice structure, the diameter of each cylindrical strut being 250 μm. (nature.com)
Form2
- This depends on the depth of overburden required to be removed and the required flexural moment capacity of the cellular form. (structurescentre.com)
- To form the AND gate , an additional binding loop was added consisting of a complementary sequence for the second input, followed by a 'caging' sequence which is complementary to the DNAzyme arm to form a stem-loop structure ( Fig. 1c ). (nature.com)
Mesh1
- This I think is a Stencil, Cellular automaton, a grid, a mesh, easily described with Markov Chain -- and a structure. (stackexchange.com)
Review1
- Structures of alkaloids involved in this review. (springer.com)
Main1
- a The parent structure of main alkaloids in Rhizoma coptidis. (springer.com)
Findings1
- Although these findings hint at possible controls on cellular and soft tissue preservation in fossil bones, they should be viewed cautiously as they are demonstrably biased by uneven sampling. (lu.se)