Ceftizoxime is a third-generation cephalosporin available for parenteral administration. (wikipedia.org)
Ceftizoxime is a third-generation cephalosporin with broad-spectrum gram-negative activity. (medscape.com)
Cefizox2
Cefizox ® (ceftizoxime for injection, USP) is a sterile, semisynthetic, broad‐spectrum, beta‐lactamase resistant cephalosporin antibiotic for parenteral (IV, IM) administration. (nih.gov)
Cefizox is supplied in ADD-vantage ® vials as ceftizoxime sodium equivalent to 1 gram or 2 grams ceftizoxime. (nih.gov)
Sodium3
Its sodium content is approximately 60 mg (2.6 mEq) per gram of ceftizoxime activity. (nih.gov)
Ceftizoxime Sodium is soluble in aqueous solution. (toku-e.com)
Ceftizoxime Sodium is commonly used in clinical in vitro microbiological antimicrobial susceptibility tests (panels, discs, and MIC strips) against Gram-positive and Gram-negative microbial isolates. (toku-e.com)
Bactericidal1
The bactericidal action of Ceftizoxime results from inhibition of cell‐wall synthesis. (nih.gov)
Imipenem1
In contrast, incubation of intraphagocytic L. pneumophila in the presence of antibiotics without intracellular activity (ceftizoxime, imipenem or amoxycillin-clavulanic acid) did not have any effect. (nih.gov)
Organisms1
Ceftizoxime is highly resistant to a broad spectrum of beta‐lactamases (penicillinase and cephalosporinase), including Richmond types I, II, III, TEM, and IV, produced by both aerobic and anaerobic gram‐positive and gram‐negative organisms. (nih.gov)
Cephalosporin1
Neu, HC (1984) Ceftizoxime: A beta‐lactamase‐stable, broad‐spectrum cephalosporin. (toku-e.com)
Injection1
Ceftizoxime for injection, USP is a white to pale yellow crystalline powder. (nih.gov)
Aerobic1
Ceftizoxime is a broad-spectrum antibiotic targeting a wide variety of Gram-positive and Gram-negative bacteria, both aerobic and anaeobic. (toku-e.com)
Effect1
Ceftizoxime had no effect on growth of Molt-4 cells at levels of 0.3 to 50 uM and no effect on L 5178y mouse lymphoma cells at 0.1 and 50 µM. (toku-e.com)
Platform1
In this study, gold nanoparticles (AuNPs) were deposited onto graphene oxide (GO) modified pencil graphite electrode (PGE) in order to construct a disposable sensor platform for the electrochemical detection of ceftizoxime (CFX). (hacettepe.edu.tr)
Presence1
however, ceftizoxime is stable in the presence of these inactivating enzymes. (toku-e.com)
Administration1
Les données sur l'acte chirurgical, le choix des antibiotiques et leur administration ont été collectées pour toutes les interventions chirurgicales réalisées chez des patients hospitalisés pendant 15 jours en mars 2010. (who.int)
Cephalosporins3
Unlike other third-generation cephalosporins, the whole C-3 side chain in ceftizoxime has been removed to prevent deactivation by hydrolytic enzymes. (wikipedia.org)
NOTE: Methicillin-resistant staphylococci are resistant to cephalosporins, including ceftizoxime. (nih.gov)
For ceftizoxime alapivoxil to compete in this segment, it would have to demonstrate excellent bioavailability, better dosing than existing cephalosporins, activity against resistant gram-positive strains, minimal side effects, and cost-effectiveness. (antiinfectivemeds.com)
Drugs1
With bmt, gvhd prophylactic immunosuppressant regimens include ceftizoxime mg im as single dose of g/kg per minute, and rel-ative valve stenosis, occasionally generalized hypertrophic cardiomyopathy in the summer and is administered in oral form is often low meq/l as a result of noninfectious virions integration of all types have been a recent study showed some children with gpd deficiency, because exposure to drugs during resuscitation. (albionfoundation.org)
Milk3
Limited information indicates that ceftizoxime produces low levels in milk that are not expected to cause adverse effects in breastfed infants. (nih.gov)
After a single 1 gram intravenous dose of ceftizoxime in 2 women, milk levels ranged from 0.31 to 0.43 mg/L from 2 to 8 hours after the dose. (nih.gov)
In six women given 1 gram of ceftizoxime intravenously, average milk levels were 0.25 mg/L 1 hour after the dose. (nih.gov)
Clinical3
Basic and clinical studies of ceftizoxime in obstetrics and gynecology. (nih.gov)
Clinical and laboratory studies on ceftizoxime (CZX) in the field of obstetrics and gynecology. (nih.gov)
Phase II clinical trials have been completed in which ceftizoxime alapivoxil 100 mg or 200 mg twice daily was orally administered to a total of 1,595 patients. (antiinfectivemeds.com)
Treatment1
8. A comparison of the efficacy and safety of ceftizoxime with doxycycline versus conventional CDC therapies in the treatment of upper genital tract infection with or without a mass. (nih.gov)
Results1
The bactericidal action of ceftizoxime results from inhibition of cell-wall synthesis. (nih.gov)
Active1
The limited data available suggest that this orally active pro-drug of ceftizoxime may be a promising antibacterial agent. (antiinfectivemeds.com)