- The endocytic pathways used by different viruses include clathrin-mediated endocytosis, uptake via caveolae, macropinocytosis, and novel nonclathrin, noncaveolae pathways that have been recently described (Figure1). (medscape.com)
- MARV assembles and buds from the host cell plasma where MARV matrix protein (mVP40) dimers associate with anionic lipids at the plasma membrane inner leaflet and undergo a dynamic and extensive self-oligomerization into the structural matrix layer. (uci.edu)
- The authors hypothesized that G protein-coupled receptor/inhibitory G protein (G i ) activation leads to caveolin trafficking to mitochondria. (silverchair.com)
- By immunocytochemistry, it was shown that podocalyxin and the actin binding protein ezrin are co-expressed in podocytes and co-localize along the apical plasma membrane, where they form a co-immunoprecipitable complex. (embl-heidelberg.de)
- Viral fusion proteins at the surface of enveloped viruses mediate apposition and fusion of the viral and cellular membranes, allowing the viral nucleocapsid to enter the cell. (medscape.com)
- Trafficking of caveolin to mitochondria is essential for adaptation to cellular stress though the trafficking mechanisms remain unknown. (silverchair.com)
- [ 25 ] An alternative explanation is that peptides generated by the trypsin cleavage of VP4 activate the membrane-destabilizing properties of the viral outer capsid proteins. (medscape.com)