• Galactokinase catalyzes the second step of the Leloir pathway, a metabolic pathway found in most organisms for the catabolism of α-D-galactose to glucose 1-phosphate. (wikipedia.org)
  • An enzyme that catalyzes the reversible reaction of α-d-glucose 1-phosphate UDPgalactose to produce UDPglucose and α-d-galactose 1-phosphate. (theodora.com)
  • MS = An enzyme that catalyzes the transfer of UMP from UDPglucose to galactose 1-phosphate, forming UDPgalactose and glucose 1-phosphate. (doctorinternet.com)
  • Cytosolic galactose-1-phosphate uridylyltransferase (GALT) catalyzes the reaction of alpha-D-galactose 1-phosphate and UDP glucose to form D-glucose 1-phosphate and UDP galactose (Reichardt & Woo 1991). (reactome.org)
  • The causative mutation in LUAb7 turned out to be a missense mutation in gtaB , a UTP-glucose-1-phosphate uridylyltransferase. (biologists.com)
  • GtaB (known as GalU in E. coli ) catalyzes glucose-1-phosphate to UDP-glucose conversion, which is required for cell wall synthesis. (biologists.com)
  • The enzyme glucose-1-phosphate thymidylyltransferase (RffH), the product of therffh gene, catalyzes one of the steps in the synthesis of enterobacterial common antigen (ECA), a cell surface glycolipid found in Gram-negative enteric bacteria. (canada.ca)
  • This enzyme catalyzes conversion of galactose-1-phosphate and UDP glucose to UDP galactose and glucose-1-phosphate. (medscape.com)
  • Glucose 1-phosphate is the direct product of the reaction in which glycogen phosphorylase cleaves off a molecule of glucose from a greater glycogen structure. (ecmdb.ca)
  • In glycogenesis, free glucose 1-phosphate can also react with UTP to form UDP-glucose, by using the enzyme UDP-glucose pyrophosphorylase. (ecmdb.ca)
  • Periplasmic acid glucose-1-phosphatase (G-1-Pase) encoded by gene Agp is necessary for the growth of Escherichia coli in a minimal medium containing glucose-1-phosphate (G-1-P) as the sole source of carbon. (ecmdb.ca)
  • Comment: In the Leloir pathway, galactokinase (galK) forms galactose 1-phosphate, a uridyltransferase (galT) uses glucose 1-phosphate to form UDP-galactose, an epimerase (galE) forms UDP-glucose, and this is converted to glucose 1-phosphate by the same uridyltransferase. (lbl.gov)
  • Glucose-1-Phosphate Adenylyltransferase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (wakehealth.edu)
  • An ATP-dependent enzyme that catalyzes the addition of ADP to alpha-D-glucose 1-phosphate to form ADP-glucose and diphosphate. (wakehealth.edu)
  • This graph shows the total number of publications written about "Glucose-1-Phosphate Adenylyltransferase" by people in this website by year, and whether "Glucose-1-Phosphate Adenylyltransferase" was a major or minor topic of these publications. (wakehealth.edu)
  • Below are the most recent publications written about "Glucose-1-Phosphate Adenylyltransferase" by people in Profiles. (wakehealth.edu)
  • Three enzymes are required in the Leloir pathway: galactokinase, galactose-1-phosphate uridylyltransferase, and UDP-galactose 4-epimerase. (wikipedia.org)
  • [ 9 ] Both patients probably had galactose-1-phosphate uridyltransferase (GALT) deficiency, which is the most common enzyme deficiency that causes hypergalactosemia. (medscape.com)
  • It reversibly catalyzes the conversion of UDPglucose to UDPgalactose. (doctorinternet.com)
  • The Leloir pathway catalyzes the conversion of galactose to glucose. (wikipedia.org)
  • Overview: Lactose utilization in GapMind is based on MetaCyc pathway lactose degradation II via 3'-ketolactose ( link ), pathway III via beta-galactosidase ( link ), or uptake by a PTS system followed by hydrolysis of lactose 6'-phosphate. (lbl.gov)
  • Comment: The tagatose 6-phosphate pathway involves the isomerization of galactose 6-phosphate to tagatose-6-phosphate (by lacAB), phosphorylation to tagatose 1,6-bisphosphate (by lacC), and an aldolase. (lbl.gov)
  • The enzyme is found predominantly in the nuclei and catalyzes the final reaction in the major pathway for the biosynthesis of NAD in mammals. (uams.edu)
  • Galactokinase is an enzyme (phosphotransferase) that facilitates the phosphorylation of α-D-galactose to galactose 1-phosphate at the expense of one molecule of ATP. (wikipedia.org)
  • Galactokinase catalyzes the first committed step of galactose catabolism, forming galactose 1-phosphate. (wikipedia.org)
  • Galactose is phophorylated at C1 by ATP in a reaction catalyzed by galactokinase. (flashcardmachine.com)
  • Galactokinase converts galactose to galactose-1-phosphate and is not a common deficiency. (medscape.com)
  • By using a genomic approach, we found that in macrophages, MLL4 (also known as Wbp7) was required for the expression of Pigp, an essential component of the GPI-GlcNAc transferase, the enzyme catalyzing the first step of glycosylphosphatidylinositol (GPI) anchor synthesis. (gsea-msigdb.org)
  • It cannot travel down many metabolic pathways and must be interconverted by the enzyme phosphoglucomutase in order to become glucose 6-phosphate. (ecmdb.ca)
  • FBP is the product of the reaction 3 of glycolysis, so it acts as a feed-forward activator of the enxyme that catalyzes step 10. (flashcardmachine.com)
  • The incidence of galactosemia is approximately 1 case per 40,000-60,000 persons. (medscape.com)
  • Or, both uptake and phosphorylation are catalyzed by a PTS system. (lbl.gov)
  • What is the advantage of activating pyruvate kinase with fructose-1,6-bisphosphate? (flashcardmachine.com)
  • Comment: Glucose can be taken up and then phosphorylated to glucose 6-phosphate by the kinase glk. (lbl.gov)
  • Nitrate reductase is phosphorylated in the dark by the calcium-dependent protein kinase (CDPK) and the sucrose non-fermenting related kinase 1 (SnRK1) that initiates the interaction of the enzyme with the 14-3-3 proteins and its inactivation. (biomedcentral.com)
  • Or, glucose is oxidized to glucono-1,5-lactone in the periplasm (by gdh), hydrolyzed to gluconate (by gnl), oxidized to 2-ketogluconate (by gadh123), taken up by kguT, phosphorylated to 2-dehydro-6-phosphogluconate (by kguK), reduced to gluconate 6-phosphate (by kguD), dehydrated by edd to 2-dehydro-3-deoxy-gluconate 6-phosphate, and cleaved by aldolase eda to pyruvate and D-glyceraldehyde 3-phosphate. (lbl.gov)
  • mitochondrial pyruvate carrier 1. (gsea-msigdb.org)
  • Each monomer has an overall α/β fold and consists of two domains, a larger nucleotide binding domain (residues 1-115, 222-291) and a smaller sugar-binding domain (116-221), with the active site located at the domain interface. (canada.ca)
  • Glycogen phosphorylase, the product of the glgP Gene, catalyzes glycogen breakdown by removing glucose units from the nonreducing ends in Escherichia coli. (ecmdb.ca)
  • In mammals, trimethylation of lysine 4 in histone H3, a modification localized at the transcription start sites of active genes, is catalyzed by six enzymes (SET1a and SET1b, MLL1?MLL4) whose specific functions are largely unknown. (gsea-msigdb.org)
  • GALM (glactose mutorotase, aldose1-epimerase) catalyzes the interconversion of the alpha and the beta anomers of hexose sugars like glucose and galactose and is not common. (medscape.com)
  • Chitin is a linear copolymer of N -acetyl- d -glucosamine (GlcNAc) and d -glucosamine units, linked by a β -(1-4) glycosidic bond, although predominantly comprising GlcNAc units [ 2 ] . (encyclopedia.pub)
  • 1069\930\BAD95974.1\Azospirillum brasilense\Azospirillum brasilense genes for dihydrodipicolinatesynthase/N-acetylneuraminate lyase, L-Arabinose 1-dehydrogenase,ABC-type sugar transport system periplasmic component, partial andcomplete cds. (or.jp)
  • An enzyme that catalyzes the conversion of ATP into a series of (2'-5') linked oligoadenylates and pyrophosphate in the presence of double-stranded RNA. (umassmed.edu)
  • An enzyme that catalyzes reversibly the transfer of the adenylyl moiety of ATP to the phosphoryl group of NMN to form NAD+ and pyrophosphate. (uams.edu)
  • Incidence widely varies (ie, 1 case in 70,000 people in the UK but 1 case in 16,476 people in Ireland. (medscape.com)
  • strong class="kwd-title" Keywords: Fingolimod, Cardiovascular, Side Effect, Multiple Sclerosis Introduction Multiple sclerosis (MS) is considered as a chronic autoimmune disease with increasing prevalence and incidence,1,2 which led to a significant expansion in the range of therapeutic options.3 Therapeutic strategies direct immune modulation and control of inflammatory processes. (himafund.org)
  • A phosphate group is transferred to the sugar, and Asp-186 may be deprotonated by water. (wikipedia.org)
  • β -(1,6)-branched glucan of the cell wall is bound to proteins or other polysaccharides, the composition of which may vary according to the fungal species, although it generally comprises highly mannosylated glycoproteins and mannoproteins. (encyclopedia.pub)
  • Its location corresponds well to that in a structurally similar domain of N-acetylglucosamine-1-phosphate uridylyltransferase (GlmU). (canada.ca)
  • This is a recognized pharmacological effect of fingolimod, mediated by modulation of S1PR subtype 1 (S1P1) on atrial myocytes, which is similar to vagal stimulation. (himafund.org)
  • As depicted in Figure 1 , the cell wall comprises a twin-layer structure, the innermost layer of which is a relatively conserved structural skeletal layer (crosslinked chitin-glucan inner layer) comprising chitin and β -(1,3)-branched glucan, whereas the heterogeneous outer layer consists of other polysaccharides and glycoproteins [ 19 ] [ 20 ] . (encyclopedia.pub)
  • Supplementary Materials01: Supplemental Figure 1. (himafund.org)
  • Results Computer contained fibrous, 1C3 m Supplementary Materials01: Supplemental Figure 1. (himafund.org)
  • Histone methyltransferases catalyze site-specific deposition of methyl groups, enabling recruitment of transcriptional regulators. (gsea-msigdb.org)