• There are several risk factors that contribute to the manifestation of tooth decay such as a high component of cariogenic bacteria, inadequate salivary flow, reduced exposure to fluoride, poor or incorrect oral hygiene, incorrect methods of feeding newborns, and poverty [ 4 ]. (hindawi.com)
  • 16. Caesalpinia sappan: A promising natural source of antimicrobial agent for inhibition of cariogenic bacteria. (nih.gov)
  • The silver acts as an antimicrobial agent against cariogenic bacteria and the fluoride works to help prevent further demineralization of the tooth. (colgateprofessional.com)
  • Sodium hypochlorite (NaOCl) is a highly active cytotoxic oxidant recognized to be among the most potent antiseptic and disinfectant agents against bacteria, fungi, and viruses. (medscape.com)
  • As antimicrobial agents, green tea catechins can destroy cariogenic (cavity-causing) bacteria. (purenaturenutrition.com)
  • Research shows that green tea catechins not only suppress the formation of plaque by cariogenic bacteria but also kill the bacteria themselves. (purenaturenutrition.com)
  • Moreover, the latest research indicated that cariogenic bacteria may severely influence the course of SARS-CoV-2 infection and increase risk of COVID-19 complications. (bvsalud.org)
  • Moreover, a diet rich in polyphenols prevents cariogenic bacteria and reduces the accumulation of dental plaque. (bvsalud.org)
  • The results suggest that the clove oil and eugenol could be employed as a natural antibacterial agent against cariogenic and periodontopathogenic bacteria. (campwander.com)
  • Furthermore, EPS-embedded bacteria also create highly protected and acidic microenvironments that promote cariogenic biofilm build-up and acid-dissolution of tooth enamel. (rochester.edu)
  • Cavity disinfection using antibacterial agents before cavity restoration ensures to a great extent elimination of cariogenic bacteria in the residual dental tissues and a long term restoration success. (researchsquare.com)
  • Reductions of cariogenic bacteria in mothers for the purpose of interfering or delaying transmission to the child has been shown to reduce both transmission and caries in children. (dentistryiq.com)
  • Streptococcus mutans , a commensal bacteria of the oral microflora, is the primary etiological agent strongly linked to dental caries. (informaticsjournals.com)
  • It is characterized by the demineralization of tooth enamel caused by acid produced by cariogenic dental bacteria growing on tooth surfaces, termed bacterial biofilms. (tmc.edu)
  • One of the factors of dental caries etiology is cariogenic bacteria known as Lactobacillus acidophilus . (nstproceeding.com)
  • Contains Xylitol, a sugar-free sweetener, known to reduce the number of cariogenic bacteria in the plaque, and to decrease the amount of insoluble plaque polysaccharides, making the plaque less adhesive and easier to remove through brushing. (swident.com)
  • [ 6 ] Of potentially great clinical significance, povidone-iodine can kill the major cariogenic bacterium Streptococcus mutans , and caries-prone children who received a povidone-iodine application to their entire dentition every 2-3 months experienced a marked reduction in new caries lesions compared with control children. (medscape.com)
  • 2021-03-04 · Cariogenic Streptococcus mutans is known as a predominant etiological agent of dental caries due to its exceptional capacity to form biofilms. (netlify.app)
  • Klein MI, Hwang G, Santos PH, Campanella OH, Koo H. Streptococcus mutans-derived extracellular matrix in cariogenic oral biofilms. (informaticsjournals.com)
  • The development of novel chemotherapeutic approaches against cariogenic biofilms is challenging. (rochester.edu)
  • Aim 3 will evaluate the efficacy of the developed CT-NPC in disrupting cariogenic biofilms and reducing dental caries in vivo using a rodent model of dental caries under clinically-relevant topical treatment regimen. (rochester.edu)
  • Four types of analysis were performed: 1) fluorescence microscopy of biofilms stained with Syto 9 and hexidium idodine to determine the biofilm architecture, 2) quantitative PCR (qPCR) to determine the cell number of each species per cm2, 3) vertical scanning interferometry (VSI) to determine the cariogenic potential of the biofilms, and 4) tomographic pH imaging using radiometric fluorescence microscopy after exposure to pH sensitive nanoparticles to measure the micro-environmental pH. (tmc.edu)
  • Sodium fluoride was the most commonly used caries preventive agent. (bvsalud.org)
  • Meta-analysis showed no significant difference between sodium fluoride formulations and other fluoride agents. (bvsalud.org)
  • Fluoride treatment when incorporated with re-mineralising agent had no significant effect on caries prevention CONCLUSION: Fluoride prevents radiation caries. (bvsalud.org)
  • To overcome these remarkable challenges, our previous NIH supported (DE018023) studies developed a potent anti-caries approach by combining food-derived antibiofilm agents (myricetin and farnesol) with fluoride. (rochester.edu)
  • We hypothesize that NPC will substantially amplify the efficacy of our combination therapy (CT) via increased solubility, retention and pH-activated release of active agents with fluoride. (rochester.edu)
  • Then, Aim 2 will evaluate the efficacy of optimized NPCs containing Myr and Far with fluoride (CT-NPC) using our in vitro cariogenic biofilm model. (rochester.edu)
  • In the last issue, we discussed several remineralizing agents, but did not review fluoride. (dentistryiq.com)
  • The principal mode of action of fluoride, and the other remineralizing agents, is to increase the resistance of enamel to demineralization and to promote remineralization. (dentistryiq.com)
  • Fluoride is a proven anti-caries agent, used in toothpaste to strengthen the tooth enamel and protect against demineralization. (com.bo)
  • Fluoride is the only anti-caries agent accepted by the Food and Drug Administration (FDA). (com.bo)
  • Used as a desensitizing agent in products like Colgate Gel-Kam , stannous fluoride works by occluding the dentinal tubules with a tin-rich deposit, thereby preventing the fluid movement within the dentinal tubules that is associated with pain from sensitivity. (com.bo)
  • Among the most common anti-plaque, anti-gingivitis agents are stannous fluoride and zinc citrate, both of which help to reduce biofilm and have a proven anti-gingivitis effect. (com.bo)
  • AKBA can be useful compound for the development of antibacterial agent against oral pathogens and it has great potential for use in mouthwash for preventing and treating oral infections. (biomedcentral.com)
  • However, this delicate balance is often skewed towards demineralization with poor oral hygiene and a cariogenic diet. (nih.gov)
  • The qualitative and quantitative results reveal the expected dynamics of the community profile when exposed to different sucrose conditions and the cariogenic potential of this in vitro four-species anaerobic biofilm model, thus confirming its usefulness for future analysis of primary and secondary dental caries. (tmc.edu)
  • When tooth enamel is attacked by cariogenic acids, teeth become porous, and white spot lesions appear. (dradampollockdds.com)
  • Many of these ecological approaches aim for long-term caries control by either disrupting cariogenic virulence factors without affecting bacterial viability, or include measures that can enhance the growth of health-associated, microbially diverse communities in the oral microbiome. (karger.com)
  • Dental caries or tooth decay is a prevalent global disease whose causative agent is the oral biofilm known as plaque. (whiterose.ac.uk)
  • It showed that propolis could be a useful agent in decreasing the accumulation of dental plaque. (bvsalud.org)
  • The rationale for use of chemotherapeutic agents for the control or prevention of dental caries dictates a more holistic understanding of the plaque microcommunity. (dentistryiq.com)
  • Chemotherapeutic approaches must be better targeted against specific microbes with the goal of re-establishing an ecologically stable non-cariogenic plaque. (dentistryiq.com)
  • The current research targeting microbial biofilm inhibition has attracted a great deal of attention, and the search for effective antimicrobial agents against these oral pathogens could lead to identification of new agents for the prevention of dental caries and periodontal diseases arising out of dental plaque formation [ 6 ]. (biomedcentral.com)
  • To evaluate in vitro the effect of a red propolis ethanolic extract (RPE) in the prevention of growth of a cariogenic biofilm and its cytotoxic potential. (bvsalud.org)
  • Excitingly, NPC respond to acidic pH to release agents more rapidly at acidic (pathological) versus neutral (physiological) pH, greatly improving (~20-fold more effective than free agents) antibiofilm activity in vitro. (rochester.edu)
  • Ingredient Specialties, Inc. introduces Züeit® brand Sucralose, a non-caloric, non-cariogenic, high intensity sweetener made from sugar. (garudaint.com)
  • Here we employ agent-based mathematical modelling to simulate a biofilm consisting of two competing, distinct types of bacterial populations, each parameterised by their nutrient uptake and aciduricity, periodically subjected to an acid challenge resulting from the metabolism of dietary carbohydrates. (whiterose.ac.uk)
  • As dental caries with its bacterial agents is an infectious disease, and shows a vertical transmission, the control of bacterial transmission of Mutans streptococci (MS) from mother to child is desirable. (dentistryiq.com)
  • Neem: Neem is known as one of the strongest anti-bacterial agents and is used for dental care. (ayurvedant.com)
  • We demonstrated that these agents in combination severely compromise EPS-matrix assembly and cariogenic biofilm development, resulting in a highly effective anti-caries therapy in vivo. (rochester.edu)
  • Cariogenic Agents" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (ucdenver.edu)
  • EN] This article analyses, the replacement of sucrose in muffins with nine different combinations of isomaltulose and oligofructose. (upv.es)
  • Cariogenesis is a complex biological process that is influence by multiple factors and is not attributed to a sole causative agent. (tmc.edu)
  • The anti-histaminic medicines evaluated have a high erosive and cariogenic potential, as they present low pH and a high total soluble solids content. (bvsalud.org)
  • The review aims to explain the cariogenic antibacterial potential of Stevia rebaudiana Bertoni leaves extract against Lactobacillus acidophilus . (nstproceeding.com)
  • Chemotherapy of viral infections is difficult because of the timing of events of the disease process versus appearance of clinical symptoms and lack of effective agents with selective toxicity. (nih.gov)
  • Clinical trials with long‑term follow‑up demonstrated cariogenic microorganisms persist under restorations and have an important role in the development of secondary caries. (researchsquare.com)
  • To support our hypothesis, Aim 1 will optimize physicochemical properties of NPC to improve targeted delivery of our agents, and thereby potentiate their antibiofilm efficacy. (rochester.edu)
  • Moreover, because the contents of inflamed periodontal pockets are emptied into the oral cavity every 90 seconds, and relatively small amounts of antimicrobial agents are applied subgingivally, the risk for antiseptics entering the gingival tissue and causing systemic damage is virtually nonexistent. (medscape.com)
  • Ketoconazole, an orally active systemic antifungal agent, may be used for monilial infections of the oral cavity refractory to nystatin. (nih.gov)
  • The National Institute of Dental and Craniofacial Research (NIDCR) invites the small business community to apply cutting edge-technology to the design and development of novel delivery systems for rapid and/or sustained, on-demand release of therapeutic agents (e.g. antimicrobial, anti-inflammatory, antibodies, peptides, nucleotides, small molecule receptor agonists/antagonists) in the oral cavity. (nih.gov)
  • As propolis mouth rinses and propolis-based toothpastes stop the growth of pathogens of gingivitis and periodontitis, they seem to be promising not only as preventive but also as therapeutic agents [30, 45, 48, 49]. (stackexchange.com)
  • Application of the DMFT index in epidemiologic surveys throughout the United States in the 1930s and 1940s allowed quantitative distinctions in dental caries experience among communities--an innovation that proved critical in identifying a preventive agent and evaluating its effects. (cdc.gov)
  • Nystatin remains a first-choice agent for treatment of oral candidal infections. (nih.gov)
  • The aromatic molecules derived from natural sources are being explored extensively as alternative agents in oral care products. (biomedcentral.com)
  • In addition, retention of these agents at tooth-biofilm interface could be enhanced to maximize their efficacy in vivo. (rochester.edu)
  • After years of personal field investigations, McKay concluded that an agent in the public water supply probably was responsible for mottled enamel. (cdc.gov)
  • The identification of a possible etiologic agent for mottled enamel led to the establishment in 1931 of the Dental Hygiene Unit at the National Institute of Health headed by Dr. H. Trendley Dean. (cdc.gov)
  • [ 4 ] Antiseptics attack multiple components of infectious agents, practically eliminating the risk for development of resistance, and do not interact with prescription medications. (medscape.com)
  • In a sub-group analysis in this same study they found that in cariogenic shock, Noradrenaline was superior to dopamine in terms of reduction in mortality. (resus.com.au)
  • This graph shows the total number of publications written about "Cariogenic Agents" by people in this website by year, and whether "Cariogenic Agents" was a major or minor topic of these publications. (ucdenver.edu)
  • With therapeutic purpose, sick cats (two groups of 8 animals/group) were administered: anti-microbial agent (5% solution of Enrofloxacin), spasmolytic medicinal agent - RiabalReg. (cranberryinstitute.org)
  • Bartzatt, R. Central Nervous System Agents in Medicinal Chemistry, 2012. (nih.gov)
  • Potassium nitrate, as found in the Colgate Sensitive range, is another commonly used desensitizing agent. (com.bo)
  • Orange slices have been osmotically dehydrated using as osmotic agents new healthy sweeteners: isomaltulose, oligofructose and aqueous extract of stevia. (upv.es)
  • Lemon slices were osmotically dehydrated using the following healthy sweeteners as osmotic agents: tagatose, isomaltulose, oligofructose and aqueous extract of stevia. (upv.es)
  • ES] A pesar del placer asociado al consumo de golosinas, los problemas de caries, sobrepeso y aumento de glucosa en sangre asociadas a las mismas implican un control en su ingesta. (upv.es)
  • Ahora que la COVID-19 ha resaltado la importancia del control de infecciones en los consultorios dentales, hablaremos acerca del papel de los enjuagues bucales antes del procedimiento para reducir las cargas virales y bacterianas. (com.bo)
  • Ascorbic acid, one of the chief components of C. limon fruit, is a promising agent for the development of anti-caries products. (informaticsjournals.com)
  • Fermentable sugar, host factors, and cariogenic microbial flora are several agents that influence dental structure. (hindawi.com)
  • Iodophors (iodine-releasing agents) developed in the 1950s were solutions of iodine complexed with an organic carrier that largely overcame the negative aspects of iodine treatment. (medscape.com)
  • Is an excellent moisturising, texturizing and anti-crystallising agent. (zukan.es)
  • In addition to providing sweetness, it is an excellent humectant and texturizing agent. (ambujagroup.com)