Cancer patients breast neoplasms. Medical search. Frequent questions

Breast cancer metastatic mouse models are experimental approaches in which mice are genetically manipulated to develop a mammary tumor leading to distant focal lesions of mammary epithelium created by metastasis. (wikipedia.org)
Metastasis is a process of migration of tumour cells from the primary cancer site to a distant location where the cancer cells form secondary tumors. (wikipedia.org)
Breast cancer phenotypes periodically express genes in metastasis that are indispensable for the metastatic process. (wikipedia.org)
It is widely accepted that tumor metastasis is a formidable barrier to effective treatment of lung cancer. (hindawi.com)
Bone metastasis is a major determinant of treatment outcome, quality of life, and survival for lung cancer patients [ 12 - 14 ]. (hindawi.com)
Most transcriptomic signatures were highly prognostic for distant metastasis, but considerable discordance was observed on the individual patient level. (lu.se)
Within the MET141 low-risk subgroup (lowest 25th percentile of scores), 95% of patients were free of metastasis at 15 years, even in the absence of adjuvant endocrine therapy. (lu.se)
Brain metastasis is a dreaded complication that significantly reduces the quality of life in breast cancer patients . (bvsalud.org)
The data of breast cancer patients with brain metastasis who were treated with WBRT using cobalt -60 equipment between 2005 and 2009 were retrospectively collected from the departmental medical record unit. (bvsalud.org)
WBRT is an effective treatment modality for patients with brain metastasis in our resource -poor environment . (bvsalud.org)

BACKGROUND: The purpose of this study was to compare the rates of all-cause and breast cancer-specific mortality after breast-conserving surgery (BCS) only, BCS plus radiation therapy (RT), mastectomy, and the receipt of adjuvant tamoxifen in a large population-based cohort of older women with early-stage disease. (healthpartners.com)
Automated administrative databases, medical records, and tumor registries were used to identify women aged 65 years or older who received BCS or mastectomy to treat stage I or II breast cancer diagnosed from January 1, 1990, through December 31, 1994. (healthpartners.com)
Compared with women receiving mastectomy, those receiving BCS without RT were twice as likely to die of breast cancer (adjusted hazards ratio [HR]=2.19, 95% confidence interval [CI], 1.51 to 3.18). (healthpartners.com)
Breast cancer mortality rates were similar between women receiving BCS plus RT and women receiving mastectomy (adjusted HR=1.08, 95% CI, 0.79 to 1.48). (healthpartners.com)
CONCLUSIONS: Our findings indicate that older women receiving BCS alone have higher rates of breast cancer death than those receiving BCS + RT or mastectomy and that the survival benefit from tamoxifen increases with increasing duration of treatment. (healthpartners.com)
All patients underwent a mastectomy, while 4% received anthracycline chemotherapy, 8% received human epidermal growth factor receptor 2 (HER2)-targeted therapy, 16% received radiation and 71% received hormone therapy. (acc.org)
breast cancer can kill · breast cancer can be effectively treated if detected early and need not kill · the signs and symptoms of breast cancer · most breast lumps are not cancer · breast cancer is diagnosed by biopsy rather than mastectomy. (who.int)
Patients-- Commercially-insured women aged 18-64 years with ICD-9-CM procedure or CPT-4 codes for mastectomy from 1/1/2004-12/31/2011. (cdc.gov)

The observed bimodal patterns of breast cancer incidence in the U.S. suggested that breast cancer may be viewed as more than one biological entity. (duke.edu)
The incidence of CRF in breast cancer patients is higher than that in other types of cancers [ 1 ], among which up to 33% of patients experience fatigue five years after the end of breast cancer treatment [ 8 ]. (springer.com)
The incidence and 10-year survival of interval breast cancers in Wales. (medigraphic.com)
The global incidence of breast cancer (BC) is rising, especially in low- and middle-income countries. (karger.com)
BC has the highest incidence rate of all cancers in women worldwide (1.67 million) and accounts for over 500,000 deaths annually [ 2 ]. (karger.com)
In light of widespread statin consumption and increases in cancer incidence, the association between statins and cancer incidence may be relevant for cancer prevention. (cdc.gov)
Early pregnancy and early oophorectomy lower the incidence of breast neoplasm. (who.int)
In contrast, late menopause is associated with an increase in the incidence of breast cancer. (who.int)
The following table presents the incidence of various breast pathology. (who.int)
The purpose of this health consultation is to evaluate cancer incidence in a population living near the Zonolite/W.R. Grace facility in Hamilton, New Jersey. (cdc.gov)
The Zonolite study area (see Figure 2) for the evaluation of cancer incidence consisted of the population residing in select census tracts (CT) or census block groups (BG) in three municipalities. (cdc.gov)
Objective-- The National Healthcare Safety Network classifies breast operations as clean procedures with an expected 1-2% surgical site infection (SSI) incidence. (cdc.gov)
In contrast to the low incidence reported by NHSN, breast surgery SSI rates reported from individual institutions vary widely. (cdc.gov)

Experimental Design: We performed a whole-transcriptome analysis of SweBCG91-RT, a randomized phase III trial of ± radiotherapy after breast-conserving surgery for node-negative stage I-IIA breast cancer. (lu.se)
METHODS: This 5-year retrospective study included patients treated with repeat-radiotherapy for recurrent BM at the "Instituto Nacional de Cancerología" of Mexico between 2015 and 2019. (bvsalud.org)
Objective Our objective was to determine whether a delay in adjuvant radiotherapy is related to a decrease in relapse-free survival and disease-specific survival of women with operable breast cancer. (bvsalud.org)
Results This study found no statistical difference for delays in adjuvant radiotherapy in patients with early breast cancer, but we noted a statistical decrease in disease-specific survival in patients with locally advanced breast cancer receiving radiotherapy after a delay of at least 60 days. (bvsalud.org)
Conclusion Waiting times for radiotherapy should be as short as reasonably achievable, given the specific risk factors in the individual patient. (bvsalud.org)
Approximately 80% of the population diagnosed with pelvic cancers present with locally advanced tumors and require concomitant chemoradiotherapy, sequential chemoradiotherapy, or radiotherapy alone. (bvsalud.org)
Radiotherapy is a fundamental part of the treatment of pelvic neoplasms. (bvsalud.org)

Patients with suspected diagnosis of locally recurrent or metastatic breast cancer, either at first relapse or after successive disease progressions, who had an appropriately preserved sample from a primary tumor and were scheduled for a biopsy of the recurrent lesion, were included. (springer.com)
It also offers the advantage of enabling simultaneous sentinel lymph node biopsy for invasive cancers. (hkmj.org)
There are two basic types of breast biopsy -- needle and surgical. (medpagetoday.com)
Fine-needle aspiration ( FNA ) biopsy is performed using a small needle to obtain samples of tissue and fluid from solid or cystic breast lesions. (medpagetoday.com)
Benefits include the ability to sample a cystic solid mass and obtain multiple samples without removing the biopsy device, although VAD presents challenges when performing multiple biopsies within the same breast. (medpagetoday.com)
A margin or edge of normal breast tissue around the tumor may also be removed, depending on the reason for the biopsy. (medpagetoday.com)
These include proliferative breast disorders, which are also associated with breast cancer development, especially if the biopsy shows a typical hyperplasia. (who.int)
Often the only way to know for sure that you have ovarian cancer is by having a biopsy of the tissue. (medlineplus.gov)

Reasons for these discrepancies may include the possibility that the molecular profile of breast cancers evolves over time and that biomarkers are heterogeneously expressed within the tumor [ 4 ] and technical inconsistencies in both tissue processing and sample evaluation. (springer.com)
Cancer Epidemiology Biomarkers and Prevention. (elsevierpure.com)

Age-specific differences in oncogenic pathway deregulation seen in human breast tumors. (duke.edu)
The highest average survival was found in patients aged between 71-80 and over 80 years who had a lobular carcinoma, who had tumors in clinical stage IIa and who were subject to radical mastectomies. (medigraphic.com)
The objective of this study was to determine the conversion rate of human epidermal growth factor receptor 2 (HER2), estrogen receptor (ER) and progesterone receptor (PR) between primary tumors and metastatic lesions in advanced breast cancer. (springer.com)
Recently, the 12th St Gallen International Breast Cancer Conference Expert Panel recommends that the subtype classification of breast cancer, namely 'HR positive' (including 'luminal A' and 'luminal B' tumors), 'HER2 amplified' and 'triple negative,' should guide the treatment plan for breast cancer patients. (springer.com)
We analyzed 223 patients (25 with preinvasive tumors and 198 with invasive and metastatic breast cancers) and 153 noncancer controls. (aacrjournals.org)
PRAME (preferentially expressed antigen in melanoma), a member of the cancer-testis antigen family, has been shown to have increased expression in solid tumors. (pipelinereview.com)
It has been said that African patients present late with aggressive tumors and face a lack of therapeutic options, resulting in short survival duration. (karger.com)
In this article, we will approach key aspects in nutrition as well as the epidemiological characteristics and toxicities in patients affected by these pelvic tumors. (bvsalud.org)
Some other rarer types of ovarian cancer are malignant germ cell tumors and stromal tumors. (medlineplus.gov)

Antibody-mediated blockade of PD-L1 induced durable tumor regression (objective response rate of 6 to 17%) and prolonged stabilization of disease (rates of 12 to 41% at 24 weeks) in patients with advanced cancers, including non-small-cell lung cancer, melanoma, and renal-cell cancer. (nih.gov)
Another way to model human breast cancer is done through the targeted inhibition of a tumor suppressor gene. (wikipedia.org)
Besides the socio-demographic variables, it was analyzed: Affected breast, Tumor location, Histological type, Clinical state at the moment of the operation and surgical technique used. (medigraphic.com)
We strongly believe that molecular targets (tumor-related and bone microenvironment based) that have been implicated in lung cancer bone metastases hold great promise in lung cancer therapeutics. (hindawi.com)
Although there are currently some available palliative treatment options for patients with bone metastases from any solid tumor origin such as radiation therapy and bone targeted/bone strengthening treatments (bisphosphonates and denosumab) that are used in clinical practice, none of them is specific for lung cancer metastases and they do not affect the poor survival outcome of this disease. (hindawi.com)
Oncologists altered their treatment plans in 31 % of patients whose tumor subtype had changed. (springer.com)
Being aware of the benefits that the correct systemic therapy provides to patients with advanced breast cancer, the Spanish Breast Cancer Research Group (GEICAM) performed a prospective, observational study to determine the conversion rate of receptor status (ER, PR and HER2) between the primary tumor and the recurrent lesion. (springer.com)
PRAME was first identified as a tumor-associated antigen through analysis of the specificity of tumor-reactive T-cell clones derived from a patient with metastatic cutaneous melanoma. (pipelinereview.com)
Studies have suggested that HOXB9 expression in breast cancer cells promotes cellular invasiveness, metastatic ability, and tumor neovascularization in the surrounding tissue in in vitro and in vivo assays. (elsevierpure.com)
These findings imply that HOXB9 overexpression may alter tumor-specific cell fates and the tumor stromal microenvironment, contributing to breast cancer progression. (elsevierpure.com)
HOXB9 expression, which promotes tumor proliferation and angiogenesis, is a significant prognostic factor in breast cancer. (elsevierpure.com)
Cancer is a disease in which abnormal cells in the body grow out of control and form a tumor. (medlineplus.gov)
Ovarian cancer is a cancerous tumor that forms in the tissues of an ovary. (medlineplus.gov)

We did a phase 3 trial to assess a neoadjuvant regimen for HER2-positive breast cancer that replaces traditional systemic chemotherapy with targeted treatment. (nih.gov)
In the subset of 886 chemotherapy-naive women treated with tamoxifen, those treated with tamoxifen for less than 1 year had a substantially higher breast cancer mortality rate than those exposed 5 years or more (adjusted HR=6.26, 95% CI, 3.10 to 12.64). (healthpartners.com)
After two courses of a highly intensive induction chemotherapy regimen with DAC (decitabine) and HAA (homoharringtonine, cytarabine), the patient suffered from severe and persistent bone marrow failure (BMF). (frontiersin.org)
Consequently, she developed ovarian cancer and secondary t-CMML and then suffered from BMF and delayed post−chemotherapy bone marrow recovery after several chemotherapy courses. (frontiersin.org)
Unfortunately, she developed ovarian cancer, secondary t-CMML, and post−chemotherapy BMF sequentially in her fifties. (frontiersin.org)
Given the unique trial design of SweBCG91-RT, where adjuvant endocrine and chemotherapy were largely unadministered, we sought to evaluate the potential of transcriptomic profiling for identifying patients who may be spared adjuvant endocrine therapy. (lu.se)
Ninety-two percent of patients were untreated by both adjuvant endocrine therapy and chemotherapy. (lu.se)
Data about sociodemographic characteristics, the type of neoplasm and the chemotherapy scheme proposed were collected. (bvsalud.org)
Significant differences in survival were revealed when comparison was made with developing countries, for people with cancers that can be successfully treated by chemotherapy (malignant lymphomas, leukaemia, testicular tumours) and modest differences for neoplasms that can be cured by early detection and surgical intervention. (who.int)

There are various patterns of prevalence of genetic mutations in the genomes of primary breast tumour and its metastases. (wikipedia.org)
Male breast cancer patients may have a high prevalence of cardiovascular conditions, according to a small study of this rare patient population which will be presented as part of ACC's Advancing the Cardiovascular Care of the Oncology Patient Virtual course, taking place Feb. 5 6. (acc.org)
According to the researchers, the high prevalence of cardiovascular conditions in male breast cancer patients requires further investigation to better understand the risk of preexisting heart disease on long-term outcomes for these patients. (acc.org)
Depression prevalence in patients with cancer varies from 3% to 55% among different studies. (bvsalud.org)
Mexico has seen an increase in cancer prevalence in its entire population as well as particular age ranges, predominantly the older segment. (bvsalud.org)
6XUYLYDO RI FDQFHU SDWLHQWV Survival data allow the calculation of the prevalence of organ-specific neoplasms in a given country and provide a basis for national cancer control strategies to be pursued in collaboration with the WHO programme on cancer control. (who.int)

4) Outcomes ▪ In 2017, after implementing the Program-2006, the MOH, for the first time, approved 38 national clinical guidelines for various malignant neoplasms(5). (slideshare.net)
Subsequently, it has been shown that PRAME is expressed in many malignant neoplasms, including cutaneous melanoma, breast carcinoma, non-small cell lung cancer, and leukemia, whereas normal healthy tissues express minimal or no PRAME , with the exception of the testis and endometrium. (pipelinereview.com)

In comparison, axillary lymphadenectomy, also called axillary lymph node dissection , is a surgical procedure where the lymph nodes are dissected out within the axilla en bloc. (medpagetoday.com)

The Global Burden of Disease Study 2020 [ 1 ] indicated that breast cancer remains the leading cancer diagnosis among females [ 2 ]. (springer.com)
Approximately 2.3 million cases of breast cancer were diagnosed worldwide in 2020 , and most were found with breast imaging. (medpagetoday.com)
115 214 patients died before age 60 years [27.7%]) of any age in the US in 2011 to 2020. (lu.se)

This underscores the need to assess molecular targets that can be exploited in prevention or clinical management of lung cancer metastases to bone. (hindawi.com)
The initial aim was to increase prevention, early detection, and treatment rates of oncological diseases and reduce cancer mortality and disability rates. (slideshare.net)
Cancer Prevention Research. (elsevierpure.com)
Asian Pacific Journal of Cancer Prevention. (edu.pe)
6FLHQWLILF VWUDWHJ\ The Agency pursues three main objectives: the identification of the causes of human cancer, the elucidation of the mechanisms of carcinogenesis and the development of scientific strategies for cancer prevention. (who.int)

All-cause mortality is decreased in women undergoing annual mammography before breast cancer diagnosis. (medigraphic.com)
Lung cancer is the second most common cancer and the leading cause of cancer related mortality in both men and women. (hindawi.com)
It is generally believed that the high mortality rate of lung cancer cases may be a result of the aggressiveness and invasive and metastatic potential of the disease and the fact that it is not easily detectable until it reaches advanced stages [ 2 ]. (hindawi.com)
Involvement of bone in lung cancer metastases is a major source of morbidity and mortality arising from skeletal related events (SREs) [ 10 ]. (hindawi.com)
IMPORTANCE: Breast cancer (BC) is the second leading cause of cancer death in women, and there is a substantial disparity in BC mortality by race, especially for early-onset BC in Black women. (lu.se)
DESIGN, SETTING, AND PARTICIPANTS: This nationwide population-based cross-sectional study was conducted using data on BC mortality in female patients in the US who died of BC in 2011 to. (lu.se)
MAIN OUTCOMES AND MEASURES: Disease-specific mortality due to invasive BC in female patients. (lu.se)
Mortality correlates with the prognosis of the primary cancer. (medscape.com)
Cancer is the leading cause of death in Israel (approximately 25% of all-cause mortality) and is a major cause of morbidity in the population (3). (cdc.gov)
Our previous study (14) demonstrated a strong negative association between persistent use of statins and all-cause mortality reduction among patients with and without a history of coronary heart disease (CHD). (cdc.gov)

abstract = "It is important to identify predictors of psychological health among breast cancer patients that can be relatively easily identified by medical care providers. (ttu.edu)
SEE NAMCS PATIENT DATASET NAMES FOR DSN ABSTRACT General Information This material provides documentation for users of the Micro-Data tapes of the National Ambulatory Medical Care Survey (NAMCS) conducted by the National Center for Health Statistics. (cdc.gov)

The group of patients object of study showed an elevated global survival, which was mainly associated to older ages, the early diagnosis of the disease and the performance of radical surgery. (medigraphic.com)
This case highlights the importance of genetic counseling in patients with hematopoietic neoplasms with high clinical suspicion for carrying cancer susceptibility gene mutations, which require timely diagnosis and personalized management. (frontiersin.org)
On a more personal level, cancer patients are already surprised by their cancer diagnosis. (acc.org)
ACC's Advancing the Cardiovascular Care of the Oncology Patient Virtual course features cardiology and oncology experts providing clinically relevant, best practice strategies for a multidisciplinary team regarding the assessment, diagnosis and management of cardiovascular concerns for cancer patients, as well as those requiring survivorship care. (acc.org)
The diagnosis of breast neoplasms usually represents an emotional burden, and it may lead to adjustment reactions and even be the trigger for affective disorders (mainly depression), anxiety or psychosis. (bvsalud.org)
The objective was to identify factors related to post-traumatic growth from the diagnosis and treatment of breast cancer. (bvsalud.org)
Background: Breast cancer diagnosis is considered meaningful stressor and often accompanied by anxiety. (unair.ac.id)
Most patients were women (75.4%) with a mean age at BM diagnosis of 51.4 years. (bvsalud.org)
The follow-up period was from the date of first statin dispensation (index date) to the date of first cancer diagnosis, death, leaving the HMO, or September 1, 2007, whichever occurred first. (cdc.gov)
Physicians should consider a diagnosis of listeriosis when treating patients who have concurrent conditions. (cdc.gov)

Introduction Women with a strong family history of breast cancer (BC) and without a known gene mutation have an increased risk of developing BC. (unimi.it)
Methods An individual patient data (IPD) meta-analysis was conducted using IPD from six prospective screening trials that had included women at increased risk for BC: only women with a strong familial risk for BC and without a known gene mutation were included in this analysis. (unimi.it)
Patients with FA gene mutation are hypersensitive to DNA damage and unable to successfully repair damaged DNA when exposed to DNA-crosslinking agents, cytotoxic chemotherapeutics, and ionizing radiation ( 3 , 4 ). (frontiersin.org)
Throughout the lifetime of patients with an FA gene mutation, DNA damage increasing accumulates, which would lead to a complex clinically and genetically heterogeneous disorder characterized by developmental abnormalities, bone marrow failure (BMF), immune deficiency, and a high risk of developing various cancers (e.g. (frontiersin.org)
The TGFBR1*6A allele was not significantly associated with breast cancer patients and only one somatic mutation was found in 71 breast cancers. (aacrjournals.org)
A total of 18 of 20 patients had at least one somatic mtDNA mutation in their tumour samples. (upm.edu.my)

As of February 24, 2012, a total of 207 patients--75 with non-small-cell lung cancer, 55 with melanoma, 18 with colorectal cancer, 17 with renal-cell cancer, 17 with ovarian cancer, 14 with pancreatic cancer, 7 with gastric cancer, and 4 with breast cancer--had received anti-PD-L1 antibody. (nih.gov)
Among patients with a response that could be evaluated, an objective response (a complete or partial response) was observed in 9 of 52 patients with melanoma, 2 of 17 with renal-cell cancer, 5 of 49 with non-small-cell lung cancer, and 1 of 17 with ovarian cancer. (nih.gov)
Herceptin) in patients with HER-2/neu overexpressing unresectable or metastatic non-small cell lung cancer (closed to accrual as of 4/16/01) or refractory locally advanced or metastatic breast cancer. (knowcancer.com)
Each year, more people die of lung cancer than of colon, breast, and prostate cancers combined. (hindawi.com)
The bone is one of the frequent metastatic sites for lung cancer occurring in a large number of patients. (hindawi.com)
Bone metastases can cause a wide range of symptoms that could impair quality of life of lung cancer patients and shorten their survival. (hindawi.com)
Thus, this paper discusses some of the emerging molecular targets that have provided insights into the cascade of metastases in lung cancer with the focus on bone invasion. (hindawi.com)
It is anticipated that the information gathered might be useful in future efforts of optimizing lung cancer treatment strategies. (hindawi.com)
Lung cancer is a significant public health burden in the USA. (hindawi.com)
It is estimated that, in 2014, there will be approximately 224,000 newly diagnosed cases of lung cancer and 159,000 deaths from lung cancer [ 1 ]. (hindawi.com)
There are two main subcategories of lung cancer: nonsmall cell lung cancer (NSCLC) and small cell lung cancer (SCLC). (hindawi.com)
In fact, over two-thirds of lung cancer patients have regional lymph-node involvement or distant metastases at the time of presentation [ 3 ]. (hindawi.com)
The bone is one of the most common metastatic sites for lung cancer [ 8 , 9 ]. (hindawi.com)
Thus, in this report, we will assess the data on lung cancer bone metastases with the intention of evaluating key molecular targets that could be applied in optimizing lung cancer treatment strategies. (hindawi.com)
Alongside, patients underwent screenings for breast, rectal and lung cancers. (slideshare.net)
Lung and breast cancer were the most prevalent neoplasms (43.9% each). (bvsalud.org)
lung and breast cancers are more likely to affect the thoracic spine. (medscape.com)
Leptomeningeal metastases spread by means of diffuse or multifocal seeding of the meninges from systemic cancer (eg, lung or breast cancer, melanoma, lymphoma). (medscape.com)
It is well documented that exposure to asbestos is strongly associated with malignant and nonmalignant respiratory diseases, including asbestosis, mesothelioma, and lung cancer, and to a lesser extent, with digestive cancers (ATSDR 2001). (cdc.gov)
A major epidemiological study on environmental tobacco smoke has been completed and revealed a significant dose-response relationship between passive smoking (at home or at the workplace) and lung cancer. (who.int)

Localization of palpable breast masses can be done manually by palpation or with imaging guidance via mammography, MRI, or ultrasound. (medpagetoday.com)

It also confirms the genetic heterogeneity between the primary neoplasm of breast cancer patients and their respective metastases. (wikipedia.org)
These results reinforce the recommendation for performing confirmatory biopsies of metastases, not only to avoid misdiagnosis of breast cancer relapse, but also to optimize treatment (clinicaltrials.gov identifier: NCT01377363). (springer.com)
BACKGROUND: Most studies evaluating factors associated with the survival of patients with brain metastases (BM) have focused on patients with newly diagnosed BM. (bvsalud.org)
Patients with more than three brain deposits accounted for 71.2% of all the brain metastases . (bvsalud.org)

Metastatic breast cancer represents the most devastating attribute of cancer and it is considered an advanced-stage event. (wikipedia.org)
Background: Metastatic breast cancer patients are now living longer but cope with potential symptoms of metastatic disease and prolonged cancer treatment. (psu.edu)
Objective: To qualitatively assess nutritional problems and concerns of women with metastatic breast cancer and to explore how to address these problems within an existing eHealth platform. (psu.edu)
Methods: Semistructured interviews were conducted with 21 women with metastatic breast cancer participating in an ongoing eHealth study. (psu.edu)
The respondents reported diverse experiences and perspectives regarding nutrition and diet in the context of metastatic breast cancer within each theme. (psu.edu)
Conclusion: Findings indicate the importance of providing women with metastatic breast cancer with information about nutrition that is tailored to their specific disease, as these patients report both nutritional problems and uncertainty regarding nutritional strategies. (psu.edu)

Non-FA (or underlying FA) patients harboring heterozygous germline FA gene mutations may also face an increased risk of developing bone marrow failure, primary immunodeficiency disease, and hereditary cancer predisposition syndromes. (frontiersin.org)
Ovarian cancer that is caused by inherited genetic changes is called hereditary ovarian cancer. (medlineplus.gov)

This study aimed to analyze the correlation between religious coping with serum cortisol levels and anxiety symptoms on late-stage of breast cancer patients at Dr. Soetomo Hospital, Surabaya. (unair.ac.id)
We used Brief RCOPE to assess patients' religious coping, Beck Anxiety Inventory (BAI) to measure the symptoms of anxiety, and chemiluminescence method to measure serum cortisol in the morning. (unair.ac.id)

Introduction: CHEK2 mutations are associated with increased risk of having neoplasms of various organs, including thyroid, breast, colon, renal and ovarian cancers. (endocrine-abstracts.org)
Most ovarian cancers are caused by genetic changes that happen during your lifetime. (medlineplus.gov)

Participants included 38 patients who underwent primary allogeneic bone marrow transplantation. (magiran.com)
All patients who underwent occult breast lesion localisation by either ultrasonography- or stereotactic-guided radioguided occult lesion localisation or hookwire localisation from August 2003 to December 2007 were included. (hkmj.org)
A total of 141 consecutive, invasive ductal carcinoma patients who underwent surgical treatment were examined. (elsevierpure.com)

Anti-PD-L1 antibody was administered every 14 days in 6-week cycles for up to 16 cycles or until the patient had a complete response or confirmed disease progression. (nih.gov)
We hypothesize that this germline variant may be involved in development and progression of breast cancer. (aacrjournals.org)
These data suggest that the germline Int7G24A variant may represent a risk factor for invasive breast cancer and a marker for breast cancer progression. (aacrjournals.org)
Tumour development, histology and grade of breast cancers: prognosis and progression. (who.int)

SRs/meta-analyses that explored the effects of exercise interventions on CRF in breast cancer patients compared with the routine methods of treatment and care were retrieved from nine databases. (springer.com)
METHODS/DESIGN: Breast cancer patients (N=327) having pain (ratings≥5) are recruited and randomly assigned to: 1) PCST-Full or 2) PCST-Brief. (duke.edu)
For occult breast lesions, to retrospectively compare the performance of radioguided and hookwire methods in terms of ease of localisation and surgical procedures, and the ability to obtain a specimen with a clear margin. (hkmj.org)
Methods Data on 1000 patients diagnosed with breast cancer were recorded. (bvsalud.org)

Molecular cancer therapeutics. (elsevierpure.com)

The majority of patients 79% had invasive ductal carcinoma. (acc.org)
The Int7G24A allele was evident in 32% of patients with preinvasive neoplasms and 48% of patients with invasive breast cancers compared with 26% controls ( P = 0.00008). (aacrjournals.org)
In addition, 11 (5.6%) homozygous Int7G24A carriers were found in patients with invasive breast cancers, whereas only 3 (2%) homozygous carriers were found in the control group. (aacrjournals.org)
Breast cancer can be divided into two main groups: non-invasive or carcinoma in situ, and invasive carcinoma. (who.int)

Lifestyle modifications consist of three components including diet, exercise, and cognitive-behavioral therapy which can reduce side effects of breast cancer. (magiran.com)
This overview of systematic reviews aims to critically appraise and consolidate evidence from current systematic reviews (SRs)/meta-analyses on the effects of exercise interventions on cancer-related fatigue (CRF) in breast cancer patients. (springer.com)
Exercise played a favorable role in alleviating CRF in breast cancer. (springer.com)
More rigorously designed clinical studies are needed to specify the exact exercise type, duration, frequency, and intensity to have an optimal effect on CRF in breast cancer patients. (springer.com)

It was shown that PRAME-specific CD8+ T cells isolated from healthy individuals and patients with advanced melanoma were able to recognize and lyse cells expressing HLA class I and high levels of PRAME . (pipelinereview.com)

survival analysis, breast neoplasms, surgery. (medigraphic.com)
To characterize the survival of patients with breast cancer at ten years of surgery. (medigraphic.com)
A number of 196 patients operated for breast cancer were analyzed by the Kaplan-Meier method over a period of ten years of survival after surgery. (medigraphic.com)
For instance, the five-year survival rate for patients with (stage IA) after surgical resection is close to 70% but the five-year survival rate for patients with stage IV (metastatic disease) is as low as 2% [ 4 ]. (hindawi.com)
BACKGROUND/AIMS: Pain is common in cancer patients and results in lower quality of life, depression, poor physical functioning, financial difficulty, and decreased survival time. (duke.edu)
The relapse-free survival and disease-specific survival were also calculated in relation to the number of patients. (bvsalud.org)

Characteristics and results of breast cancer in elderly females treated with curative intent. (medigraphic.com)
Chi-square test was conducted and showed no statistically significant relationship between the classification of BDI and the variables tested (characteristics related to patient and cancer-specific). (bvsalud.org)
Evidence on treatment from prospective randomized trials that address the specific characteristics of African patients is lacking. (karger.com)
The current results suggest that demographic patient characteristics may indeed be useful in identifying both when and for whom depressive symptoms are particularly likely to be problematic. (ttu.edu)

Targeted expression of oncogenes in mouse mammary epithelial cells is a way of modeling human breast cancer. (wikipedia.org)

Mammary cancers in mice can be caused by genetic mutations that have been identified in human cancer. (wikipedia.org)
Here, we present the case of a 54-year-old female patient with multiple FA gene mutations. (frontiersin.org)
(B) The patient was born with four Fanconi anemia (FA) gene mutations and germline predisposition to cancers. (frontiersin.org)
She developed ovarian cancer, and then the altered FA pathway plus exposure to cytotoxic drugs promoted the emergence of acquired somatic mutations and the NUP98-HOXC11 fusion, all of which contributed to the development of secondary t-CMML. (frontiersin.org)
Coexistence of papillary thyroid cancer and malignancies of other organs in patients carrying CHEK2 gene mutations case series. (endocrine-abstracts.org)
Coexistence of thyroid and breast cancers was observed in female carriers of CHEK2 gene mutations. (endocrine-abstracts.org)
Mitochondrial DNA (mtDNA) mutations, oxidative stress and resistance to cell deaths increase one's risk for breast cancer. (upm.edu.my)
This study aims to identify the types of mtDNA mutations, levels of protein expression of oxidative stress, apoptosis, autophagy and mitophagy in breast cancer as well as the association between mtDNA mutations and the levels of protein expression. (upm.edu.my)
Ovarian cancer happens when there are changes (mutations) in the genetic material (DNA). (medlineplus.gov)

The findings also highlight the need for cardiologists and cardio-oncologists to be involved in male breast cancer treatment due to the common risk factors and potential cardiotoxic effects of breast cancer treatment. (acc.org)
We also selected articles on BC epidemiology, risk factors, clinical presentation, and cancer control in Africa. (karger.com)
Age and gender, diet and weight are risk factors for developing breast cancer. (who.int)
However, in 70% of breast cancer patients no risk factors can be identified. (who.int)

Purpose: There is currently no molecular signature in clinical use for adjuvant endocrine therapy omission in breast cancer. (lu.se)
Conclusions: Transcriptomic profiling identifies patients with an excellent outcome without any systemic adjuvant therapy in clinically low-risk patients of the SweBCG91-RT and METABRIC cohorts. (lu.se)

CONCLUSIONS: Novel RCT designs may provide information that can be used to optimize behavioral pain interventions to be adaptive, better meet patients' needs, reduce barriers, and match with clinical practice. (duke.edu)

Due to the rarity of male breast cancer, there is no cardiovascular data from larger clinical trials or population studies," explains Michael Ibrahim , fourth year medical student at Georgetown University and one of the study authors. (acc.org)

These changes have been predicted by cancer epidemiologists for many years, but even they are surprised by the speed at which these changes are occurring, e.g., the emergence of cancer of the breast, colon and prostate in several countries in which these neoplasms were hardly known only 20 to 30 years ago. (who.int)

Our study demonstrated that persistent use of statins is associated with a lower overall cancer risk and particularly the risk of incident hematopoietic malignancies. (cdc.gov)

Two hundred and twenty five breast cancer patients receiving radiation treatment completed four surveys over the course of 13 months that included measures of both their physical health and depressive symptoms. (ttu.edu)
Up to 90% of patients develop gastrointestinal symptoms as a result of acute injury to the small and large intestine, particularly in the mucosa. (bvsalud.org)
What are the symptoms of ovarian cancer? (medlineplus.gov)
Ovarian cancer may not cause early signs or symptoms. (medlineplus.gov)
By the time you do have signs or symptoms, the cancer is often advanced. (medlineplus.gov)

For cancer survivors and supporters! (knowcancer.com)
Published trials have investigated the co-efficacies of the two or three components of lifestyle modifications, especially dietary and cognitive-behavioral interventions in breast cancer survivors. (magiran.com)
This protocol is about a meta-analysis which will systematically report the simultaneous effects of dietary intervention or physical activity with cognitive-behavioral therapy, or three of them on quality of life, the recurrence levels and anthropometric measurements among patients with breast cancer and survivors. (magiran.com)

The genetic profiles of primary and metastatic lesions in breast carcinomas show a large extent of clonal pertinence between lesions. (wikipedia.org)
FNA is indicated for patients with a mammographic abnormality or palpable breast lesions. (medpagetoday.com)
Benefits include cost-effectiveness, simplicity, and ability to perform multiple biopsies of separate lesions within the same breast quadrant. (medpagetoday.com)
Metastatic lesions that involve the spinal cord affect about 5-10% of patients with cancer. (medscape.com)

Distinct Receptor Tyrosine Kinase Subsets Mediate Anti-HER2 Drug Resistance in Breast Cancer. (duke.edu)
An intronic variant ( Int7G24A ) of TGF-β receptor type I ( TGFBR1 ) is associated with kidney and bladder cancers in our recent study. (aacrjournals.org)

Several studies have shown IDPs involved by suspicious cellular proliferations seen on CNB are more commonly associated with cancer upon excision than IDPs without atypia diagnosed on CNB (see Prognosis and Predictive Factors ). (medscape.com)

Comparative performance of multiview stereoscopic and mammographic display modalities for breast lesion detection. (duke.edu)

Thus, PRAME is a potential candidate for cancer immunotherapy because it is expressed by a variety of tumours and can induce T-cell immune responses. (pipelinereview.com)
Samples were 20 matched breast tumours with corresponding normal breast tissues. (upm.edu.my)

Human breast cancer metastasizes to multiple distant organs such as the brain, lungs, bones and liver. (wikipedia.org)

The lack of large data makes it even more important to individualize cardiovascular assessment and management based on each patient's unique oncologic, therapeutic and preexisting cardiovascular risk profile to support them through cancer treatment into survivorship. (acc.org)
Breast cancer can be grouped into different subtypes, as shown below, to characterize and compare therapeutic mortalities. (who.int)

A recessive variant of XRCC4 predisposes to non- BRCA1/2 breast cancer in chinese women and impairs the DNA damage response via dysregulated nuclear localization. (duke.edu)
There are also certain genetic changes that can raise your risk of ovarian cancer, including changes called BRCA1 and BRCA2 . (medlineplus.gov)

Grade 3 or 4 toxic effects that investigators considered to be related to treatment occurred in 9% of patients. (nih.gov)
however, some patients remain at risk of relapse or death for many years after treatment of early-stage disease. (nih.gov)
Between June 25, 2014, and June 15, 2015, we randomly assigned 444 patients to neoadjuvant treatment with trastuzumab emtansine plus pertuzumab (n=223) or docetaxel, carboplatin, and trastuzumab plus pertuzumab (n=221). (nih.gov)
Fatigue and lymphatic pain are the most common and debilitating long-term adverse effects of breast cancer treatment. (duke.edu)
Tachyarrhythmia preexisted in 8% of patients and developed in 13% of patients while undergoing treatment. (acc.org)
Two patients were found to have decreased ejection fraction, and two patients developed heart failure after treatment. (acc.org)
Cardio-oncologists or cardiologists should pay close attention to the proposed treatment plan and be part of a multidisciplinary cancer care team to evaluate the patients' cardiovascular risk prior to and through cancer treatments. (acc.org)
Similar to the pretreatment consultation with radiation oncology, breast surgery, and medical oncology, an upfront cardiovascular risk assessment provides greater comfort and further minimizes psychological surprise with cardiovascular complications going into cancer treatment. (acc.org)
Female breast cancer patients (n=20) without neoadjuvant treatment were recruited with informed consents. (upm.edu.my)
Thirty women diagnosed with breast cancer undergoing treatment at the Base Hospital participated in this study. (bvsalud.org)
These results point to the importance of identifying these variables in the psychosocial profile of cancer patients, and mainly to the need to develop interventions that can promote the maintenance and development of protective factors in the face of treatment stressors. (bvsalud.org)
The mean radiation dose used for WBRT was 30 Gy in 10 fractions, and total responses recorded were 86.5% with 53.8% complete improvement in patients ' performance status 4 weeks after WBRT treatment . (bvsalud.org)
We have showed that the increase occurred in persons with cancer or other conditions whose treatment included acid-suppressing medication ( 7 ). (cdc.gov)

Anatomy10

Organisms2

Diseases69

Chemicals and Drugs49

Analytical, Diagnostic and Therapeutic Techniques and Equipment76

Psychiatry and Psychology3

Phenomena and Processes42

Disciplines and Occupations2

Anthropology, Education, Sociology and Social Phenomena2

Humanities1

Information Science7

Named Groups2

Health Care32

Geographicals3

Metastasis10

Mastectomy8

Incidence13

Radiotherapy7

Biopsy8

Biomarkers2

Tumors9

Tumor13

Chemotherapy9

Prevalence6

Malignant neoplasms2

Lymph Nodes1

20203

Prevention5

Mortality10

Abstract2

Diagnosis10

Mutation6

Lung20

Mammography1

Metastases4

Metastatic breast cancer6

Hereditary2

Serum2

Ovarian cancers2

Underwent3

Progression4

Methods4

Therapeutics1

Invasive4

Exercise4

Melanoma1

Survival6

CHARACTERISTICS4

Oncogenes1

Mutations9

Risk Factors4

Adjuvant2

Conclusions1

Clinical trials1

Prostate1

Hematopoietic1

Symptoms5

Survivors3

Lesions4

Receptor2

Prognosis1

Detection1

Tumours2

Organs1

Therapeutic2

BRCA12

Treatment13