Calcifying nanoparticles (CNPs) play an important role in kidney stone formation, but the mechanism(s) are unclear. (nih.gov)
The term "calcifying nanoparticles" (CNPs) has also been used as a conservative name regarding their possible status as a life form. (wikipedia.org)
Atherosclerotic2
Here we revealed that CPB isolated from calcified atherosclerotic plaques and artificially synthesised CPB are morphologically and chemically indistinguishable entities. (bvsalud.org)
PEG forms strong ionic bonds with hydroxyl apatite (HAp), the primary component of calcified atherosclerotic lesions¹⁴. (philips.hu)
Composites1
Ayyub OB, Kofinas P. Enzyme Induced Stiffening of Nanoparticle-Hydrogel Composites with Structural Color. (ctsicn.org)
Calcium2
Calcium phosphate bions (CPB) are biomimetic mineralo-organic nanoparticles which represent a physiological mechanism regulating the function, transport and disposal of calcium and phosphorus in the human body. (bvsalud.org)
In all species, hydrated and anhydrous amorphous calcium carbonate nanoparticles were precursors for skeletal growth, as previously observed in a single species. (news-oceanacidification-icc.org)
Calcification3
The research team developed a nanoparticle, known as a micelle, which attaches itself and lights up calcification to make it easier for smaller blockages that are prone to rupture to be seen during imaging. (usc.edu)
In our case, we demonstrated that our nanoparticle binds to calcification in the most commonly used mouse model for atherosclerosis and also works in calcified vascular tissue derived from patients," Chin said. (usc.edu)
The company's lead asset ELT-001 is an EDTA-loaded nanoparticle conjugated with a proprietary monoclonal antibody for the treatment of vascular calcification. (elastrin.com)
Proteins1
The cytotoxicity of different representative molecules, namely small organic molecules, proteins and nanoparticles (NP), was measured after 24 h of exposure using the fluorescent dye pair Hoechst 33342 and SYTOX orange. (nature.com)
Gelatin1
In this study, a porous piezoelectric hydrogel bone scaffold was fabricated by incorporating polydopamine (PDA)-modified ceramic hydroxyapatite (PDA-hydroxyapatite, PHA) and PDA-modified barium titanate (PDA-BaTiO 3 , PBT) nanoparticles into a chitosan/gelatin (Cs/Gel) matrix. (biomedcentral.com)
Vascular1
The team has tested their nanoparticle on calcified cells in a dish, within a mouse model of atherosclerosis, as well as using patient-derived artery samples provided by vascular surgeon, Magee, which shows their applicability not only in small animals but in human tissues. (usc.edu)
MeSH1
Nanoparticles" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (ctsicn.org)
20221
Greenville, SC, U.S, April 7, 2022 - Elastrin Therapeutics Inc., a privately held biotechnology company leveraging a platform to develop therapeutics that render calcified tissue and organs supple again, today announced the closing of a $10 million funding round led by Kizoo Technology Capital, a leading early-stage investor in breakthrough rejuvenation technologies. (elastrin.com)
Corals1
Such ion-by-ion diffusion and attachment may occur from the supersaturated calcifying fluid known to exist in corals, or from a dense liquid precursor, observed in synthetic systems but never in biogenic ones. (news-oceanacidification-icc.org)
Cells1
Our micelle nanoparticles demonstrate minimal toxicity to cells and tissue and are highly specific to hydroxyapatite calcifications," Chin said. (usc.edu)
Applications1
Vojtech JM, Cano-Mejia J, Dumont MF, Sze RW, Fernandes R. Biofunctionalized prussian blue nanoparticles for multimodal molecular imaging applications. (ctsicn.org)
Formation1
Zinc transport is important to nanoparticle formation. (newswise.com)
Potential2
Mussel-inspired polydopamine composite mesoporous bioactive glass nanoparticles: an exploration of potential metal-ion loading platform and in vitro bioactivity. (us.es)
Effect of boron-doped mesoporous bioactive glass nanoparticles on C2C12 cell viability and differentiation: potential for muscle tissue application. (us.es)
Size1
Dr. Chi calls the beginnings of the stones "calcified nanoparticles" and puts their size into perspective. (newswise.com)