• Common inbred strains include BALB/c, C3H, C57BL/6 and DBA. (uwm.edu)
  • Reproductive performance consisting of mean litter size, number of pups that wean (wean: born ratio) and mean reproductive index of three inbred mice strains, which are BALB/cMlac, C57BL/6Mlac and DBA/2Mlac, were investigated to provide some basic information on the breeding and maintaining of a foundation colony. (mahidol.ac.th)
  • This study was performed to produce reference data for eye toxicity tests and to investigate the ophthalmic diseases of 408 ICR mice and 119 BALB/c mice, which are commonly used as subjects in toxicity tests. (go.jp)
  • BALB/c mice, 31.9%) and the incidence gradually decreased with age. (go.jp)
  • Strain differences in susceptibility regarding stomach carcinogenesis due to N-methyl-N-nitrosourea were examined in males of six strains of mice: BALB/cA (BALB), C57BL/6N (C57BL6), CBA/JN (CBA), C3H/HeN (C3H), DBA/2N (DBA/2), and CD-1 (ICR). (jax.org)
  • There are over 400 documented inbred strains of mice. (uwm.edu)
  • Differences in hepatic fibrosis and granuloma size in several strains of mice infected with Schistosoma japonicum. (rsbmt.org.br)
  • An inbred strain of mouse. (ouhsc.edu)
  • An inbred strain of mouse that is widely used in BIOMEDICAL RESEARCH . (nih.gov)
  • One naturally occurring genetic defect in mice results in an animal with no hair that is called a nude. (uwm.edu)
  • Mice, Inbred C57BL" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (uchicago.edu)
  • Mice, Inbred DBA" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings) . (ouhsc.edu)
  • Here, using a genetic labeling method in adult mice, we found that continuous neurogenesis results in the replacement of the majority of granule neurons in the olfactory bulb and a substantial addition of granule neurons to the hippocampal dentate gyrus. (nih.gov)
  • Genetic ablation of newly formed neurons in adult mice led to a gradual decrease in the number of granule cells in the olfactory bulb, inhibition of increases in the granule cell number in the dentate gyrus and impairment of behaviors in contextual and spatial memory, which are known to depend on hippocampus. (nih.gov)
  • This strain is commonly used as genetic background for transgenic mouse models. (uchicago.edu)
  • Genetic-linked variation in susceptibility of mice to Schistosomiasis mansoni . (rsbmt.org.br)
  • Inbred strains are the result of at least 20 generations of brother-sister mating. (uwm.edu)
  • After inbreeding for 20 generations, a surprisingly high incidence of hydronephrosis was encountered and we finally obtained a strain of mice with a very high incidence of severe hydronephrosis affected on both sides of kidney and in both sexes as the process of inbreeding has been increased. (mahidol.ac.th)
  • This substrain is at least (a number>20 by definition) generations removed from the originating JAXR Mice strain and has NOT been re-infused with pedigreed stock from The Jackson Laboratory. (nomura-siam.com)
  • Previously, a low incidence of mild hydronephrosis was observed mostly in male mice and found only on the right kidney. (mahidol.ac.th)
  • These mice are known for their low incidence of mammary cancers and their resistance to exogenous tumor induction and are widely used for studies on cancer and immunology and for those in the field of toxicity and microbiology. (nomura-siam.com)
  • Analysis of a quantitative trait locus for seizure susceptibility in mice using bacterial artificial chromosome-mediated gene transfer. (jefferson.edu)
  • The most commonly used methods for catching and picking up mice are grasping the animal near the tip of the tail, between thumb and forefinger, or by grasping the tail near the base or the neck between the ends of a smooth tipped forceps. (uwm.edu)
  • Young mice ( pups) should be grasped by the cupping the hands around the whole body or by grasping the skin across the shoulder blades with a forceps. (uwm.edu)
  • This study was designed to assess the effectiveness of carbon monoxide (CO) as an alternative euthanasia agent for mouse and rat pups on postnatal days (PND) 0 to 12. (bvsalud.org)
  • We demonstrate that TRPC6 deficiency in mice not only results in anxious and depressive behavior, but also reduces excitability of hippocampal CA1 pyramidal neurons and dentate gyrus granule cells. (afpm.org.my)
  • Methamphetamine self-administration in mice decreases GIRK channel-mediated currents in midbrain dopamine neurons. (ouhsc.edu)
  • More laboratory mice are used in research every year than any other animal species. (uwm.edu)
  • C57BL/6, was introduced to the Jackson Laboratory to form the C57BL/6J strain. (nomura-siam.com)
  • C57BL/6J mice were introduced from the Jackson Laboratory to NIH and were maintained as C57BL6N. (nomura-siam.com)
  • In addition, C57BL/6J mice at F166 were introduced from the Jackson Laboratory to CLEA Japan, Inc., in 1989, at which time their production and supply was started. (nomura-siam.com)
  • Differences in hepatic fibrosis in ICR, C3H, and C57 BL/6 mice infected with Schistosoma manson . (rsbmt.org.br)
  • C57BL/6NJcl mice grow slightly better than C57BL/6JJcl mice, but there are no marked differences between the two sublines. (nomura-siam.com)
  • Scholars@Duke publication: Cadherin-11 expressed in association with mesenchymal morphogenesis in the head, somite, and limb bud of early mouse embryos. (duke.edu)
  • To determine the developmental expression pattern of this molecule, we performed in situ hybridization analysis on early mouse embryos. (duke.edu)
  • Genome-edited mice were also obtained using frozen-warmed pronuclear embryos with clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated system (Cas) nucleases introduced using the technique for animal knockout system by electroporation (TAKE) method, which were transferred to females with pseudopregnancy induced on the day of embryo transfer. (nature.com)
  • In 1921, Littel obtained mice from Lathrop and named a strain of mice that was derived from the mating of female 57 and male 52 and that consistently exhibited black hair as C57BL. (nomura-siam.com)
  • Independent variation in susceptibilities of six different mouse strains to induction of pepsinogen-altered pyloric glands and gastric tumor intestinalization by N-methyl-N-nitrosourea. (jax.org)
  • C57BL/6N mice at F121 were introduced from NIH to the Central Institute for Experimental Animals in 1978, and then to CLEA Japan, Inc. at F121+25 in 1988. (nomura-siam.com)
  • In mice and rats, females require mating stimulation for the maintenance of pregnancy. (nature.com)
  • The production of female mice with pseudopregnancy induced using sonic vibration was as efficient as rats. (nature.com)
  • However, relatively little information is available on humane aspects of anesthesia and euthanasia in neonatal mice and rats. (bvsalud.org)
  • The study demonstrates that CO may be a potential alternative for preweanling mice and rats at PND6 or older but is not appropriate for neonates at PND5 or younger. (bvsalud.org)
  • The current study was designed based on existing literature regarding minimal exposure times for preweanling rats and mice euthanized with carbon dioxide. (bvsalud.org)
  • The study evaluated the minimal time that adult rats and mice must remain in 100% carbon dioxide for death to be irreversible on removal. (bvsalud.org)
  • Adult rats (14 stocks and strains) and mice (more than 40 stocks and strains) were euthanized using a 50% volume per minute displacement rate of carbon dioxide for 2 min. (bvsalud.org)
  • The goal of this study was to determine whether DNA methylation plays an important role in guiding transcriptional changes during the first 2 wk of mouse heart development, which is an important period for cardiomyocyte maturation, loss of proliferative capacity and loss of regenerative potential. (nih.gov)
  • Gene expression profiling (RNA-seq) and genome-wide sequencing of methylated DNA (MBD-seq) identified dynamic changes in the cardiac methylome during postnatal development [2545 differentially methylated regions (DMRs) from P1 to P14 in the mouse]. (nih.gov)
  • Systems genetics analysis of mouse chondrocyte differentiation. (jefferson.edu)
  • We found that TWK10 not only enhanced muscle strength in young mice, but also prevented the aging-related loss of muscle strength in aged mice, which was accompanied by elevated muscle glycogen levels. (frontiersin.org)
  • Foxe1 Deletion in the Adult Mouse Is Associated With Increased Thyroidal Mast Cells and Hypothyroidism. (uchicago.edu)
  • Kallikrein genes are associated with lupus and glomerular basement membrane-specific antibody-induced nephritis in mice and humans. (ouhsc.edu)
  • This study examined the application of this method for the induction of pseudopregnancy in mice. (nature.com)
  • This study demonstrated that induction of pseudopregnancy by sonic vibration was also possible in mice. (nature.com)
  • This graph shows the total number of publications written about "Mice, Inbred C57BL" by people in this website by year, and whether "Mice, Inbred C57BL" was a major or minor topic of these publications. (uchicago.edu)
  • The major SNTX, CTX and PLA2 toxins were isolated with intravenous median lethal doses determined as 0.13, 1.06 and 0.50μg/g in mice , respectively. (afpm.org.my)
  • Fine mapping of a major QTL influencing morphine preference in C57BL/6 and DBA/2 mice using congenic strains. (jefferson.edu)
  • Immunoglobulin G subclasses confer protection against Staphylococcus aureus bloodstream dissemination through distinct mechanisms in mouse models. (uchicago.edu)
  • TWK10-treated mice also experienced an increase in short-chain fatty acid (SCFA)-producing bacteria and higher overall levels of gut SCFA. (frontiersin.org)
  • Effects of Depilatory Cream Formulation and Contact Time on Mouse Skin. (uchicago.edu)
  • We synthesized the hyperforin analog Hyp13, which shows similar binding to TRPC6 and recapitulates TRPC6-dependent anxiolytic and antidepressant effects in mice . (afpm.org.my)
  • Hydronephrosis was accidentally observed when autopsied the out bred ICR mice in routine health monitoring program. (mahidol.ac.th)
  • Applications Tested: This 17A2 antibody has been tested by flow cytometric analysis of mouse splenocytes. (thermofisher.com)
  • Plastic restraint devices can be used to hold mice and other rodents for longer periods of time. (uwm.edu)
  • To study the function and expression of this molecule, we cloned mouse, cad-11 cDNA. (duke.edu)
  • These mice have deficiencies in their immune systems and thereby prove valuable in the study of immune diseases and cancer. (uwm.edu)
  • This study examined the application of sonic vibration to induce pseudopregnancy in mice. (nature.com)
  • In this study, the effect of TWK10 on the progression of age-related impairments was investigated in mice. (frontiersin.org)
  • Single CAR-T cell treatment controls disseminated ovarian cancer in a syngeneic mouse model. (uchicago.edu)
  • Retinal ganglion cell protection by 17-beta-estradiol in a mouse model of inherited glaucoma. (ouhsc.edu)
  • Outbred mouse stocks are also used in research. (uwm.edu)
  • Breeder selection for breeding was carried out by using the progeny selection method, which selects offspring based on their characteristics, in combination with the breeding principle of maximum avoidance of inbreeding and the rotational mating system. (mahidol.ac.th)
  • Gut microbiota modulates bleomycin-induced acute lung injury response in mice. (uchicago.edu)
  • Re-evaluation of 1,2-dimethylhydrazine in the mouse bone marrow micronucleus assay: Observation of a positive response. (cdc.gov)
  • Figure 1) If the skin is grasped too far from the head the mouse will be able to turn and bite the handler. (uwm.edu)