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Burkitt LymphomaLymphomaLymphoma, B-CellLymphoma, Non-HodgkinLymphoma, Large B-Cell, DiffuseLymphoma, T-CellHerpesvirus 4, HumanLymphoma, FollicularLymphoma, AIDS-RelatedTranslocation, GeneticChromosomes, Human, 6-12 and XLymphoma, B-Cell, Marginal ZoneEpstein-Barr Virus Nuclear AntigensChromosomes, Human, 13-15Glutamate FormimidoyltransferaseGenes, mycProto-Oncogene Proteins c-mycB-LymphocytesEpstein-Barr Virus InfectionsLymphoma, Mantle-CellLymphoma, T-Cell, CutaneousHodgkin DiseaseLymphoma, T-Cell, PeripheralLymphoma, Large-Cell, AnaplasticChromosomes, Human, Pair 14VincristineTumor Cells, CulturedGerminal CenterOncogenesAntibodies, Monoclonal, Murine-DerivedCyclophosphamideIn Situ Hybridization, FluorescenceAntigens, CD20Chromosomes, Human, 1-3Genes, Immunoglobulin Heavy ChainCell Line, TumorImmunophenotypingImmunoglobulin Heavy ChainsCell LineSesquiterpenes, GuaianeLeukemia, B-CellDoxorubicinGene RearrangementSesquiterpenes, EudesmaneChromosomes, Human, Pair 8NeprilysinCytogeneticsAntineoplastic Combined Chemotherapy ProtocolsLymphoma, Large-Cell, ImmunoblasticViral Matrix ProteinsHLA-A11 AntigenGenes, mybImmunohistochemistryGene Expression Regulation, NeoplasticProto-Oncogene Proteins c-bcl-2Genes, bcl-2PlasmacytomaCytarabineBase SequenceApoptosisAntibodies, MonoclonalTanacetum partheniumFlow CytometryVirus LatencyAntigens, ViralPrednisoneInhibitor of Differentiation ProteinsLymphoproliferative DisordersDNA, NeoplasmGenes, ImmunoglobulinChromosome BandingKaryotypingTreatment OutcomeMethotrexateReceptors, Antigen, B-CellCell Transformation, ViralNeoplasm ProteinsAntineoplastic AgentsEtoposideMolecular Sequence DataProto-OncogenesLeukemia, LymphoidPrognosisLymphocytesRemission InductionLymphoma, Extranodal NK-T-CellCell Transformation, NeoplasticTumor Markers, BiologicalTranscription, GeneticCell Line, TransformedPolymerase Chain ReactionGene Expression Regulation, ViralDNA, ViralChaperonin Containing TCP-1BiopsyHybrid CellsVirus ActivationNational Cancer Institute (U.S.)
Burkitt's LymphomaDiffuseTreatment of Burkitt LymphomaEndemicSubtypesSporadicMantleLymphoblastic lymphomaLeukemiaMalignantDiagnosisTumorAggressive B-cellPerson's riskHigh-grade lyMature B-cell lymChemotherapyLymph nodePrognosisAdultsMorphologyCellDLBCLOrgan transplant recipientsABSTRACTGerminal centerTherapyAfricaRecipientsInfectionSymptomsGenomeTranslocationDiseaseOutcomesPatientsRearrangementCancersAdultCellsClinicalIntensiveLymphatic systemDevelops
Burkitt's Lymphoma25
  • Burkitt's lymphoma in a patient with adenosine deaminase deficiency-severe combined immunodeficiency treated with polyethylene glycol-adenosine deaminase. (medscape.com)
  • Burkitt's lymphoma: clinicopathologic features and differential diagnosis. (medscape.com)
  • Virus particles in cultured lymphoblasts from Burkitt's lymphoma. (medscape.com)
  • On episode #374 of the science show This Week in Virology, the TWiVniks consider the role of a cell enzyme that removes a protein linked to the 5′-end of the picornavirus genome, and the connection between malaria, Epstein-Barr virus, and endemic Burkitt's lymphoma. (virology.ws)
  • Materials and Methods: We have adapted the Burkitt's lymphoma line Ramos to a serum-free medium that supports long-term survival and studied gene expression changes that occurred during the adaptation process. (lu.se)
  • Here, we report that in T-cell acute lymphoblastic leukemia (T-ALL) and Burkitt's lymphoma the MYC oncogene causes overexpression of DNA methyltransferase (DNMT) 1 and 3B, which contributes to tumor maintenance. (diagenode.com)
  • By utilizing a tetracycline-regulated MYC transgene in a mouse T-ALL (EμSRα-tTA;tet-o- MYC) and human Burkitt's lymphoma (P493-6) model, we demonstrated that DNMT1 and DNMT3B expression depend on high MYC levels, and that their transcription decreased upon MYC-inactivation. (diagenode.com)
  • Hence, shRNA-mediated knock-down of endogenous MYC in human T-ALL and Burkitt's lymphoma cell lines, downregulated DNMT3B expression. (diagenode.com)
  • We are a support and advocacy non-profit organization for Burkitt's Lymphoma patients and caregivers. (burkittslymphomasociety.com)
  • I'm not one to reach out or write reviews on books or products but feel compelled this time to let Joane know that she has truly changed my life and the lives of both my 6 year old warrior (burkitt's lymphoma survivor) and his younger brother. (gouldingconsultants.com)
  • Neurological manifestations of Burkitt's lymphoma in Ghana. (edu.gh)
  • Over a period of 2 1/4 years, 75 patients with histologically confirmed Burkitt's lymphoma were evaluated at the Korle Bu Teaching Hospital in Accra. (edu.gh)
  • Burkitt's lymphoma is characterized as being a non-Hodgkin's Lymphoma undifferentiated B cells with highly aggressive character. (bvsalud.org)
  • In this paper we aim to report a case of Burkitt's lymphoma in a child of 4 years old, explaining its clinical, tomographic and histopathological. (bvsalud.org)
  • that I was diagnosed with Burkitt's lymphoma at the age of 15 my biggest concern was maintaining my body my strength really diminished a lot. (4inspiration.ca)
  • A 9-year-old boy with a large mass in the right lower quadrant of the abdomen was diagnosed as having disseminated Burkitt's lymphoma by pleural fluid aspirate. (elsevierpure.com)
  • Ashfaq, R & Timmons, CF 1992, ' Xanthomatous pseudotumor of the small intestine following treatment for Burkitt's lymphoma ', Archives of Pathology and Laboratory Medicine , vol. 116, no. 3, pp. 299-301. (elsevierpure.com)
  • On January 3, 2020, I was diagnosed with Burkitt's lymphoma(BL)with brain metastasis, and kidney and liver failure. (lls.org)
  • Oro-facial manifestations of Burkitt's lymphoma: an analysis of 680 cases from Malawi. (bvsalud.org)
  • Burkitt's lymphoma (BL) is a highly aggressive, fast growing, mature B- cell non-Hodgkin's Lymphoma (NHL) and has one of the highest proliferation rates of any human tumour. (bvsalud.org)
  • Results: We found that Pim-1 can be located in the cytoplasm, the cytoplasm and nucleus, or the nucleus of cells of normal lymph nodes, but is only located in the nucleus in Burkitt's lymphoma cells. (elsevierpure.com)
  • An ovarian involvement by non-Hodgkin lymphoma (NHL) may include one of the four subtypes of lymphoma: diffuse large B-cell lymphoma, Burkitt's lymphoma (BL), lymphoblastic lymphoma or anaplastic large cell lymphoma. (biomedcentral.com)
  • Burkitt's lymphoma is a rare entity with a specific poorly differentiated pattern. (biomedcentral.com)
  • Here we report a case of a primary ovarian Burkitt's lymphoma with bilateral involvement in a 57 year old patient. (biomedcentral.com)
  • In Africa, EBV infection is linked to Burkitt's lymphoma. (daviddarling.info)
Diffuse11
  • Among peripheral B-cell lymphomas, the major difficulty is to differentiate BL from diffuse large B-cell lymphoma (DLBCL) , lymphoblastic lymphoma , and blastic mantle cell lymphoma (MCL) . (medscape.com)
  • In the 2008 World Health Organization (WHO) classification system, these are referred to as "B-cell lymphoma, unclassifiable, with features intermediate between diffuse large B-cell lymphoma and Burkitt lymphoma. (medscape.com)
  • Histologically, they were high grade B-cell lymphoma, not otherwise specified (8 cases), diffuse large B-cell lymphoma (2 cases) and only one was considered as atypical Burkitt lymphoma. (cun.es)
  • Burkitt-like lymphoma with 11q aberration had frequent gains of 12q12-q21.1 and losses of 6q12.1-q21, and lacked common Burkitt lymphoma or diffuse large B-cell lymphoma alterations. (cun.es)
  • These results suggest that Burkitt-like lymphoma with 11q aberration is a germinal center derived lymphoma closer to high grade B-cell lymphoma or diffuse large B-cell lymphoma rather than Burkitt lymphoma. (cun.es)
  • HGBL, not otherwise specified (NOS) is a heterogeneous, aggressive, mature B-cell lymphoma that does not meet criteria for BL, DHL, or diffuse large B-cell lymphoma NOS. (cancernetwork.com)
  • Aggressive B-cell lymphomas (Burkitt lymphoma, diffuse large B-cell lymphoma) with CD10 expression can be difficult to distinguish from follicular lymphoma by flow cytometry. (learnflowcytometry.ca)
  • Leukemic presentation of diffuse large B-cell lymphoma: an unusual pattern associated with splenic involvement. (rochester.edu)
  • CT scan of mediastinum shows diffuse lymphatic swelling (arrow) over right supraclavicular (A) , pre-vascular (B-D) and aortopulmonary (C) station with inhomogeneous enhancing after contrast media, suggestive for lymphoma. (biomedcentral.com)
  • The purpose of the study is to find out if an investigational drug called PRGN-3007 UltraCAR-T cells (PRGN-3007 T cells) can help people with ROR1-positive hematologic chronic lymphocytic leukemia (CLL), mantle cell lymphoma (MCL), acute lymphoblastic leukemia (ALL), diffuse large B-cell lymphoma (DLBCL) and solid tumor triple negative breast cancer (TNBC) malignancies. (moffitt.org)
  • I. Determine the response rate (complete and partial) in patients with relapsed or refractory Burkitt's, mantle cell or diffuse large cell non-Hodgkin's lymphoma treated with FR901228 (depsipeptide). (knowcancer.com)
Treatment of Burkitt Lymphoma1
  • This paper describes the treatment of Burkitt lymphoma (BL) from the time of its discovery in Africa up to the present. (hindawi.com)
Endemic9
  • Burkitt lymphoma can be divided into three main clinical variants: the endemic, the sporadic, and the immunodeficiency-associated variants. (wikipedia.org)
  • The sporadic type of Burkitt lymphoma (also known as "non-African") is the most common variant found in places where malaria is not endemic such as North America and parts of Europe. (wikipedia.org)
  • The tumor cells have a similar appearance to the those of the classical endemic Burkitt lymphoma. (wikipedia.org)
  • The endemic variant of Burkitt lymphoma is in almost all cases associated with EBV infection. (wikipedia.org)
  • However, the almost ubiquitous presence of the virus in the endemic variant of Burkitt lymphoma suggests that it contributes to the development and/or progression of this variant. (wikipedia.org)
  • Burkitt lymphoma (BL) is an aggressive B-cell malignancy with endemic, sporadic and immunodeficiency-associated variants. (bmj.com)
  • Burkitt lymphoma (BL) can be classified into three forms which differ in geographic distribution and Epstein-Barr virus (EBV) association: endemic (eBL), sporadic (sBL) and HIV-associated BL ( table 1 ). (bmj.com)
  • Classic Burkitt lymphoma is endemic in central Africa and constitutes 30% of childhood lymphomas in the US. (msdmanuals.com)
  • Subtypes of Burkitt lymphoma include African endemic, sporadic and immunodeficiency-associated. (utoronto.ca)
Subtypes1
  • 1 A significant minority of these cases were the especially aggressive B-cell lymphomas Burkitt lymphoma (BL) and high-grade B-cell lymphoma (HGBL), the latter of which includes the histologic subtypes HGBL with MYC and BCL2 and/or BCL6 translocations (conventionally referred to as double-hit lymphoma [DHL]) and HGBL, not otherwise specified (NOS). (cancernetwork.com)
Sporadic1
  • In sporadic (non-African) Burkitt lymphoma , abdominal disease predominates, often arising in the region of the ileocecal valve or the mesentery. (msdmanuals.com)
Mantle1
Lymphoblastic lymphoma1
  • Lymphoblastic lymphoma may be histologically similar to Burkitt lymphoma (BL), however, it is a T-cell lymphoma that expresses T-cell markers in addition to TdT, which are usually negative in BL cases. (medscape.com)
Leukemia9
  • Adult Burkitt leukemia and lymphoma. (medscape.com)
  • The Leukemia & Lymphoma Society (LLS)gave my family so much help during my journey. (lls.org)
  • The Leukemia & Lymphoma Society® (LLS) is a global leader in the fight against blood cancer. (lls.org)
  • The LLS mission: Cure leukemia, lymphoma, Hodgkin disease and myeloma, and improve the quality of life of patients and their families. (lls.org)
  • The Leukemia & Lymphoma Society is a 501(c)(3) organization, and all monetary donations are tax deductible to the fullest extent allowed by tax laws. (lls.org)
  • B Lymphoblastic Leukemia/Lymphoma With Burkitt-like Morphology and IGH/MYC Rearrangement: Report of 3 Cases in Adult Patients. (ipathology.cn)
  • Isolated MYC rearrangement without other recurrent genetic abnormalities is rare in B lymphoblastic leukemia/lymphoma (B-ALL/LBL), with most cases reported in pediatric patients. (ipathology.cn)
  • Human T-cell leukemia/lymphoma virus (HTLV-1): Infection with HTLV-1 increases a person's risk of lymphoma and leukemia. (daviddarling.info)
  • Lymphoma Australia is the only incorporated charity in Australia dedicated to solely providing education, support, awareness and advocacy initiatives for Australians touched by lymphoma and chronic lymphocytic leukemia (CLL). (lymphoma.org.au)
Malignant7
  • Malignant lymphoma in African children. (medscape.com)
  • Non-Hodgkin Lymphomas Non-Hodgkin lymphomas are a heterogeneous group of disorders involving malignant monoclonal proliferation of lymphoid cells in lymphoreticular sites, including lymph nodes, bone marrow, the. (msdmanuals.com)
  • Burkitt lymphoma is the most rapidly growing human tumor, and pathology reveals a high mitotic rate, a monoclonal proliferation of B cells, and a "starry-sky" pattern of benign macrophages that have engulfed apoptotic malignant lymphocytes. (msdmanuals.com)
  • Malignant lymphoma - mixed small and large cell: (single agent) 40 to 50 mg/kg IV in divided doses over 2 to 5 days OR 10 to 15 mg/kg IV every 7 to 10 days OR 3 to 5 mg/kg IV twice weekly. (wikidoc.org)
  • Malignant lymphoma - mixed small and large cell: (single agent) oral cyclophosphamide is usually administered at dosages in the range of 1 to 5 mg/kg/day for both initial and maintenance dosing. (wikidoc.org)
  • The diagnosis of malignant lymphoma was established after bilateral adnexectomy and histological study of the excised tissue. (biomedcentral.com)
  • This malignant disease makes up about 85 percent of non-Hodgkin lymphomas (NHL) in the United States. (newhopemedicalcenter.com)
Diagnosis3
Tumor2
  • Burkitt lymphoma (BL) must be distinguished from other primary abdominal tumors in childhood, including Wilms tumor , neuroblastoma , and peripheral neuroectodermal tumor . (medscape.com)
  • We investigated the potential of lymphoblastoid cell lines (LCL) and Burkitt lymphoma (BL) cell lines to produce and respond to the cytotoxins, tumor necrosis factor-alpha (TNF-alpha) and lymphotoxin (LT). Transformation in vitro of peripheral blood B cells by EBV from seven different donors resulted in spontaneous production of both LT (11,542 pg/ml +/- 7546, mean +/- SD) and, to a lesser extent, TNF-alpha (197 pg/ml +/- 174). (ox.ac.uk)
Aggressive B-cell2
  • The aggressive B-cell lymphomas BL, DHL, and HGBL, NOS are unique diseases with specific pathogenesis and biology. (cancernetwork.com)
  • Burkitt lymphoma is an aggressive B-cell non-Hodgkin lymphoma occurring in children and adults. (msdmanuals.com)
Person's risk2
High-grade ly1
  • Treatment protocols varied, including both high-risk ALL-type (protocol 8707) and high-grade lymphoma regimens (hyper-CVAD [cyclophosphamide, vincristine, adriamycin, and dexamethasone]), but no patient achieved continuous complete remission. (ipathology.cn)
Mature B-cell lym2
Chemotherapy5
  • [ 49 , 50 ] Moreover, patients with a Burkitt lymphoma (BL) signature who were treated with CHOP-like (cyclophosphamide, hydroxydaunorubicin hydrochloride [doxorubicin hydrochloride], vincristine and prednisone) regimens had a worse prognosis than those patients who were treated with more intense chemotherapy regimens. (medscape.com)
  • People with Burkitt lymphoma most often receive a combination of chemotherapy and targeted therapy drugs. (mylymphomateam.com)
  • Children with Burkitt lymphoma receive a combination of several chemotherapy drugs. (mylymphomateam.com)
  • Pediatric Burkitt lymphoma may be treated with between two to eight cycles of chemotherapy , depending on how advanced the cancer is. (mylymphomateam.com)
  • Adults with Burkitt lymphoma use different chemotherapy regimens (treatment plans). (mylymphomateam.com)
Lymph node2
Prognosis3
  • Burkitt lymphoma is uncommon in adults, in whom it has a worse prognosis. (wikipedia.org)
  • Two different studies explored gene-expression profiling by microarray technology as a tool to accurately diagnose Burkitt lymphoma (BL) and differentiate it from DLBCL due to the significant difference in prognosis and treatment approaches for these diseases. (medscape.com)
  • Non-Hodgkin lymphoma (NHL) represents a heterogeneous group of malignancies of different biology and prognosis. (medscape.com)
Adults4
Morphology3
  • The National Cancer Institute's Working Formulation, originally proposed in 1982, classified and grouped lymphomas by morphology and clinical behavior (ie, low, intermediate, or high grade) with 10 subgroups labeled A to J. (medscape.com)
  • The leukemic and lymphoma cells in all 3 cases demonstrated Burkitt lymphoma-like morphology with deeply basophilic cytoplasm and numerous cytoplasmic vacuoles. (ipathology.cn)
  • The Working Formulation, originally proposed in 1982, classified and grouped lymphomas by morphology and clinical behavior (ie, low, intermediate, or high grade) with 10 subgroups labeled A to J.{Ref 1} In 1994, the Revised European-American Lymphoma (REAL) classification attempted to apply immunophenotypic and genetic features in identifying distinct clinicopathologic NHL entities. (medscape.com)
Cell22
  • It makes up 40% of the HIV associated lymphomas, and it usually occurs in those with normal CD4+ T cell counts. (wikipedia.org)
  • Burkitt lymphoma is commonly associated with the infection of B cell lymphocytes with the EBV and in these cases is considered to be one form of the Epstein-Barr virus-associated lymphoproliferative diseases. (wikipedia.org)
  • To improve the understanding of Burkitt-like lymphoma with 11q aberration we have performed an analysis of copy number alterations and targeted sequencing of a large panel of B-cell lymphoma related genes in 11 cases. (cun.es)
  • P. Connor Johnson, MD, and Jeremy S. Abramson MD, MMSc, discuss available treatments for patients with Burkitt lymphoma and high-grade B-cell lymphoma. (cancernetwork.com)
  • This article reviews the current data and future directions in the management of Burkitt lymphoma (BL) and high-grade B-cell lymphoma (HGBL). (cancernetwork.com)
  • 1 BL tumour cells usually express IgM, 13 - 15 B-cell markers such as CD19, CD20 and CD22 and markers of germinal centre (GC) centroblasts such as CD10, BCL6 4 and the human germinal centre-associated lymphoma (HGAL) protein. (bmj.com)
  • Burkitt lymphoma develops in a type of white blood cell called a B lymphocyte. (mylymphomateam.com)
  • Burkitt lymphoma is a clinically aggressive form of non-Hodgkin B-cell lymphoma with an extremely rapid rate of growth, reflected by the presence of tingible body macrophages containing phagocytosed nuclear debris imparting a 'starry sky pattern. (utoronto.ca)
  • We believe that the small-bowel xanthoma in this child is an unusual, nonneoplastic, treatment- related sequela of lymphoma cell lysis and histiocytic scavenging of lipid- membranous debris. (elsevierpure.com)
  • Whether similar disparities exist among AYA with aggressive mature B-cell non-Hodgkin lymphoma (B-NHL) is unknown. (nih.gov)
  • More recent medications that doctors can use to treat TLS include B cell lymphoma-2 protein inhibitors and oral kinase inhibitors. (medicalnewstoday.com)
  • Trends in utilization and outcomes after autologous or allogeneic hematopoietic cell transplantation (HCT) for Burkitt lymphoma were analyzed in 241 recipients reported to the Center for International Blood and Marrow Transplant Research between 1985 and 2007. (elsevierpure.com)
  • Lymphotoxin acts as an autocrine growth factor for Epstein-Barr virus-transformed B cells and differentiated Burkitt lymphoma cell lines. (ox.ac.uk)
  • A histopathological examination revealed a high grade B-cell ovarian lymphoma. (biomedcentral.com)
  • Hematoxylin and eosin-stained sections (original magnifications X20, X100 and X400) show a lymphoid proliferation of small B-cells with a widely monotonous growth pattern, suggestive for high-grade B-cell lymphoma. (biomedcentral.com)
  • Survive B-cell lymphoma. (newhopemedicalcenter.com)
  • B-cell lymphomas are cancers of the lymph nodes. (newhopemedicalcenter.com)
  • Signs of B-cell lymphoma vary according to the type of B-cell lymphoma and how advanced it is. (newhopemedicalcenter.com)
  • In most cases, doctors do not know the exact causes of B-cell lymphoma and other non-Hodgkin lymphomas. (newhopemedicalcenter.com)
  • To diagnose B-cell lymphoma, your doctor will begin with a complete review of your medical history, risk factors, and other medical conditions to rule out other possible causes of your symptoms. (newhopemedicalcenter.com)
  • Why Choose Us for B-Cell Lymphoma Alternative Treatments? (newhopemedicalcenter.com)
  • New Hope Unlimited is known for its groundbreaking treatments for challenging and complex cancers, including B-cell lymphomas. (newhopemedicalcenter.com)
DLBCL1
  • DLBCL typically has larger cells, but some Burkitt lymphoma (BL) cases might have centroblast-like (large) cells intermixed with the more common medium-sized monoclonal lymphocytes, resulting in some degree of a diagnostic dilemma, especially when considering that up to 15% of DLBCL cases might test positive for the c- myc translocation. (medscape.com)
Organ transplant recipients2
  • Burkitt lymphoma arising in organ transplant recipients: a clinicopathologic study of five cases. (medscape.com)
  • Title : Burkitt lymphoma risk in U.S. solid organ transplant recipients Personal Author(s) : Mbulaiteye, Sam M.;Clarke, Christina A.;Morton, Lindsay M.;Gibson, Todd M.;Pawlish, Karen;Weisenburger, Dennis D.;Lynch, Charles F.;Goodman, Marc T.;Engels, Eric A. (cdc.gov)
ABSTRACT1
  • abstract = "Background: The Pim-1 33-kDa protein is a serine/threonine protein kinase that is capable of enhancing the rate of occurrence of c-Myc-induced lymphomas, and functions to block factor-withdrawal and genotoxic stress-induced apoptosis. (elsevierpure.com)
Germinal center1
Therapy2
  • Although Burkitt lymphoma grows quickly, it also responds quickly to therapy. (mylymphomateam.com)
  • Most people with Burkitt lymphoma receive a targeted therapy called rituximab ( Rituxan ). (mylymphomateam.com)
Africa2
  • It is named after Denis Parsons Burkitt, the Irish surgeon who first described the disease in 1958 while working in equatorial Africa. (wikipedia.org)
  • There is a low background incidence of BL worldwide (sBL), which is rarely associated with EBV and accounts for 1-2% of adult lymphoma in Western Europe and America, but eBL is associated with (EBV) in over 95% of cases and is predominant in the equatorial belt of Africa and other parts of the world where malaria is hyperendemic. (bmj.com)
Recipients1
  • Case reports of Burkitt lymphoma (BL) in transplant recipients suggest that the risk is markedly elevated. (cdc.gov)
Infection5
  • Immunodeficiency-associated Burkitt lymphoma is usually associated with HIV infection, but can also occur in the setting of post-transplant patients. (wikipedia.org)
  • The mutational landscape in Burkitt lymphoma has recently been found to differ between tumors with and without EBV infection, further strengthening the role of the virus in disease origin. (wikipedia.org)
  • Having a weak immune system (from an inherited condition, HIV infection, or certain drugs) increases the risk of developing non-Hodgkin's lymphoma. (daviddarling.info)
  • People who have HIV infection are at much greater risk of some types of non-Hodgkin's lymphoma. (daviddarling.info)
  • Epstein-Barr virus (EBV): Infection with EBV has been linked to an increased risk of lymphoma. (daviddarling.info)
Symptoms3
  • Different treatments may help cure Burkitt lymphoma, stop it from spreading, relieve symptoms, or prevent it from relapsing. (mylymphomateam.com)
  • If you have swollen lymph nodes or other symptoms that suggest non-Hodgkin's lymphoma, your doctor will help you find out whether they are from cancer or some other cause. (daviddarling.info)
  • Our medical experts have prevailed at addressing lymphoma symptoms in the past, and yet our search for more powerful therapies against lymphoma continues. (newhopemedicalcenter.com)
Genome2
  • In 2019, a pair of studies described the whole-genome sequencing (WGS)-based characterization of over 100 Burkitt lymphomas (BLs). (ashpublications.org)
  • Derived from a Burkitt′s lymphoma which does not possess the EBV genome. (sigmaaldrich.com)
Translocation3
  • This type of translocation is seen in 15% of cases of Burkitt lymphoma. (wikipedia.org)
  • This type of translocation is involved in about 5% of cases of Burkitt lympohoma. (wikipedia.org)
  • These cases seem to represent a distinct biological phenomenon, in which a MYC translocation may be acquired at an immature stage of differentiation, thus manifesting features of both B-ALL/LBL and Burkitt lymphoma. (ipathology.cn)
Disease3
  • The fact that some Burkitt lymphoma cases do not involve EBV allows that many cases of the disease are not caused and/or promoted by EBV, i.e. the virus may be an innocent passenger virus in these cases. (wikipedia.org)
  • Treatment options for Burkitt lymphoma depend on a person's disease stage and age. (mylymphomateam.com)
  • Age: Although non-Hodgkin's lymphoma can occur in young people, the chance of developing this disease goes up with age. (daviddarling.info)
Outcomes1
Patients1
  • We are grateful to be able to share stories from patients and carers, donors and supporters, about their experiences with lymphoma or CLL. (lymphoma.org.au)
Rearrangement1
  • Burkitt-like lymphoma with 11q aberration is characterized by pathological features and gene expression profile resembling Burkitt lymphoma but lack MYC rearrangement and carries an 11q-arm aberration with proximal gains and telomeric losses. (cun.es)
Cancers1
  • Burkitt lymphoma (BL), in spite of its low incidence throughout most of the world, has had a major impact upon the understanding and treatment of lymphomas and doubtless upon many other cancers. (hindawi.com)
Adult1
Cells4
Clinical1
  • A non-profit organisation created to increase understanding of Burkitt Lymphoma and to produce effective research projects and clinical trials. (burkitt-lymphoma.org)
Intensive2
  • High-risk Burkitt lymphoma treatments are usually intensive (given at high doses). (mylymphomateam.com)
  • The investigations listed here are appropriate for any new patient with AML, ALL, and Burkitt-like Leukaemia/ Lymphoma who is scheduled to receive intensive treatment . (streamliners.co.nz)
Lymphatic system1
Develops1