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  • composition
  • It is also possible to adjust the composition of bioactive glass to find out the number of hours it can persist in the body before it degrades to provide the necessary support as long as is needed. (idataresearch.com)
  • In this study, six differing compositions of calcium-strontium-sodium-zinc-silicate (Ca-Sr-Na-Zn-Si) glass bone grafts were immersed in pH 7.4 and pH 3 solutions to study the effect of glass composition on zinc and strontium release in a normal and extreme physiological environment. (springer.com)
  • grafts
  • this is particularly true for block grafts, in which a small block of bone is placed whole in the area being grafted. (wikipedia.org)
  • For these types of grafts, extraction of the part of the periosteum and accompanying blood vessels along with donor bone is required. (wikipedia.org)
  • tissues
  • The ability to bond to living tissues and the high pore volume allow to exploit mesoporous bioactive materials also simply for local drug delivery allowing to overcome the limitations of systemic delivery: therapeutic concentrations at the site of infection, but for short periods of time, forcing repeated dosing for longer periods. (springer.com)
  • This layer enables the bioactive glass to form a firm bonding with both soft and hard tissues. (idataresearch.com)
  • vitro
  • In vivo study confirmed that BMSCs combined with Lap initiated a less severe immune response and had an improved effect on bone regeneration compared with Lap alone, which corresponded with the in vitro evaluation. (springer.com)
  • Fixation
  • Fixation devices such as guided bone regeneration membranes, collagen membranes, titanium mesh, and bone screws may be used to counteract mechanical stresses on the graft during healing. (dentalproductshopper.com)
  • In this context, given the wide use of calcium phosphates (CaPs) and bisphosphonates (BPs) for the therapy of bone-related affections, there was great interest to investigate the chemistry taking place when combining the two systems since: (i) it could provide better insight in the mechanism of BP fixation on bones (ii) such combination could act as efficient BP delivery systems when implanted in bone defects. (scientific.net)
  • ceramics
  • Mark's research has mainly been applying solid state NMR to inorganic materials which has included, ceramics, clay processing, sol-gel formed materials, aluminosilicate glasses and their interaction with water, oxides, energy materials and metallic alloys. (lancaster.ac.uk)
  • marrow
  • Hematoxylin and eosin (HE) staining and toluidine blue staining were used to analyze the number of bone marrow osteoblasts and adipocytes. (healinglightseminars.com)
  • the bone histomorphology analysis results indicated that LLLI could increase BFR and mineral apposition rate (MAR), increase the number of osteoblasts and decrease the number of adipocytes in the bone marrow in the old group. (healinglightseminars.com)
  • biological
  • Duchène P. Stimulation of biological function with bioactive glass. (springer.com)
  • The choice of which physical, chemical and biological cues to use is based on the properties of the nerve environment, which is critical in creating the most desirable environment for axon regeneration. (wikipedia.org)
  • osteoporosis
  • Influence of N-methyl pyrrolidone on the activity of the pulp-dentine complex and bone integrity during osteoporosis. (uzh.ch)
  • Incorporating trace elements, such as zinc and strontium, known to have beneficial and therapeutic effects on bone may provide a more viable bone graft option for those suffering from metabolic bone diseases such as osteoporosis. (springer.com)
  • graft material
  • As native bone grows, it will generally replace the graft material completely, resulting in a fully integrated region of new bone. (wikipedia.org)
  • Osteoconduction occurs when the bone graft material serves as a scaffold for new bone growth that is perpetuated by the native bone. (wikipedia.org)
  • Osteoblasts from the margin of the defect that is being grafted utilize the bone graft material as a framework upon which to spread and generate new bone. (wikipedia.org)
  • In the very least, a bone graft material should be osteoconductive. (wikipedia.org)
  • A bone graft material that is osteoconductive and osteoinductive will not only serve as a scaffold for currently existing osteoblasts but will also trigger the formation of new osteoblasts, theoretically promoting faster integration of the graft. (wikipedia.org)
  • osteoblasts
  • Osteoinduction involves the stimulation of osteoprogenitor cells to differentiate into osteoblasts that then begin new bone formation. (wikipedia.org)
  • 1990
  • Leblanc AD, Schneider VS, Evans HJ, Engelbretson DA, Krebs JM (1990) Bone mineral loss and recovery after 17 weeks of bed rest. (springer.com)
  • allograft
  • The pathology of bone allograft. (springer.com)
  • For example, enamel matrix derivative has been shown to enhance the osteoinductive effect of demineralized freeze dried bone allograft (DFDBA), but will not stimulate new bone growth alone. (wikipedia.org)
  • microstructure
  • The bone density, μCT microstructure, biomechanical properties, and the immunohistochemical and biochemical indicators of angiogenesis were also measured. (springer.com)
  • The SCI group showed significantly reduced tibial metaphysis bone density, μCT bone microstructure, tibial biomechanical properties, indicators of angiogenesis, and intraosseous blood vessel parameters compared to the NX group. (springer.com)
  • The rats in the treatment group were treated with LLLI for 12 weeks, and then the microstructure of bones was analyzed by micro-computed tomography (micro-CT) scanning. (healinglightseminars.com)
  • Micro-CT results showed that compared with those in the young group, the bone mineral density (BMD) in the old group was significantly decreased, and the trabecular microstructure was seriously damaged. (healinglightseminars.com)
  • facilitate
  • Bioactive glass is brittle in nature, but offers a strong, lightweight and biodegradable framework to facilitate healing. (idataresearch.com)
  • For the regenerative purposes BCPs show better performance than HA because of the higher solubility of β-TCP compound, which facilitate the subsequent bone ingrowth in the implant. (scientific.net)
  • A nerve guidance conduit (also referred to as an artificial nerve conduit or artificial nerve graft, as opposed to an autograft) is an artificial means of guiding axonal regrowth to facilitate nerve regeneration and is one of several clinical treatments for nerve injuries. (wikipedia.org)
  • trabecular
  • Waarsing JH, Day JS, Verhaar JA, Ederveen AG, Weinans H (2006) Bone loss dynamics result in trabecular alignment in aging and ovariectomized rats. (springer.com)
  • autograft
  • An autograft - a bone taken from another part of the body - is the preferred implant for repairing the bone since it will not be at risk of infection. (idataresearch.com)
  • In the Zn-HA group the area of neoformed bone was larger than in the HA group, but smaller than in the autograft. (scientific.net)
  • An autograft may also be performed without a solid bony structure, for example using bone reamed from the anterior superior iliac spine. (wikipedia.org)
  • bioactivity
  • Branda F, Arcobello-Varlese F, Costantini A, Luciani G. Effect of the substitution of M 2 O 3 (M=La,Y,In,Ga,Al) for CaO on the bioactivity of 2.5CaO _ 2SiO 2 glass. (springer.com)
  • orthopedic
  • Doctors that do bone graft procedures are commonly orthopedic surgeons, otolaryngology head and neck surgeon, neurosurgeons, craniofacial surgeons, oral and maxillofacial surgeons, podiatric surgeons and periodontists, dental surgeons, oral surgeons and implantologists. (wikipedia.org)
  • spinal
  • Jiang SD, Shen C, Jiang LS, Dai LY (2007) Differences of bone mass and bone structure in osteopenic rat models caused by spinal cord injury and ovariectomy. (springer.com)
  • Liu D, Zhao CQ, Li H, Jiang SD, Jiang LS, Dai LY (2008) Effects of spinal cord injury and hindlimb immobilization on sublesional and supralesional bones in young growing rats. (springer.com)
  • Dauty M, Perrouin Verbe B, Maugars Y, Dubois C, Mathe JF (2000) Supralesional and sublesional bone mineral density in spinal cord-injured patients. (springer.com)
  • Similar techniques are also being explored for nerve repair in the spinal cord but nerve regeneration in the central nervous system poses a greater challenge because its axons do not regenerate appreciably in their native environment. (wikipedia.org)
  • screws
  • Also, it may be necessary to use implanted devices, such as joint replacements, plates or screws to replace or reinforce damaged or weak bones and joints. (idataresearch.com)
  • mechanically
  • Also, the implant must be morphologically and mechanically compatible to maintain good contact with the recipient bone to support the growth of bone cells. (idataresearch.com)
  • formation
  • Carlisle E. Silicon: a requirement in bone formation independent of vitamin D1. (springer.com)
  • These results suggest that BMSCs could ameliorate the inflammation induced by Lap and enhance its bone formation. (springer.com)
  • Towler DA (2007) Vascular biology and bone formation: hints from HIF. (springer.com)
  • The bone formation rate (BFR) was analyzed by double fluorescent labeling with calcein and tetracycline. (healinglightseminars.com)
  • rats
  • Nian H, Qin LP, Chen WS, Zhang QY, Zheng HC, Wang Y (2006) Protective effect of steroidal saponins from rhizome of Anemarrhena asphodeloides on ovariectomy-induced bone loss in rats. (springer.com)
  • Iwamoto J, Takeda T, Ichimura S, Sato Y, Yeh JK (2003) Comparative effects of orchidectomy and sciatic neurectomy on cortical and cancellous bone in young growing rats. (springer.com)